SIGMAR1

General Information

Gene Name       : SIGMAR1
Gene ID             : ENSG00000147955.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SIGMAR1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SIGMAR1ENSG00000147955.1640.8751.7146.29ENCSR000AEF
HepG2SIGMAR1ENSG00000147955.1687.9760.5774.27ENCSR985KAT
K562SIGMAR1ENSG00000147955.1654.3253.8354.08ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SIGMAR1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SIGMAR1 RNA is bound by 17 proteins.  







eCLIP assay for SIGMAR1 is not avaliable on ENCORE database.





17 proteins are bound to SIGMAR1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr93463535434635479-3'-UTR,intron-Distal,intron-Proximal3.9517214.01675K562HNRNPL
chr93463529634635354-3'-UTR,intron-Distal4.900548.16758K562HNRNPL
chr93463550334635628-3'-UTR,intron-Distal4.619116.08927HepG2IGF2BP3
chr93463523834635334-3'-UTR,intron-Distal4.8660512.32753HepG2UPF1
chr93463480034634823-3'-UTR,intron-Distal3.5834321.27628HepG2HNRNPL
chr93463533134635405-3'-UTR,intron-Distal,intron-Proximal3.331444.86917HepG2LIN28B
chr93463501034635147-3'-UTR,intron-Distal4.9827642.68573HepG2PCBP2
chr93463483534634877-3'-UTR,intron-Distal3.5055419.74885HepG2HNRNPL
chr93463556534635643-3'-UTR,CDS,intron-Distal4.0697616.70503HepG2LARP4
chr93463537334635449-3'-UTR,intron-Distal,intron-Proximal4.6089613.89495HepG2UPF1
chr93463502334635095-3'-UTR,intron-Distal3.935937.32810HepG2UPF1
chr93463527834635327-3'-UTR,intron-Distal3.436918.01516HepG2LARP4
chr93463548134635591-3'-UTR,intron-Distal,intron-Proximal4.206246.14390K562PABPC4
chr93463503734635103-3'-UTR,intron-Distal3.461046.91779HepG2LARP4
chr93463532134635421-3'-UTR,intron-Distal,intron-Proximal5.3430212.95331HepG2IGF2BP3
chr93463564334635693-3'-UTR,CDS,intron-Distal3.7681016.84765HepG2LARP4
chr93463482334634828-3'-UTR,intron-Distal3.4843718.11050HepG2HNRNPL
chr93463480134634871-3'-UTR,intron-Distal4.9188735.66362K562HNRNPL
chr93463479234634800-3'-UTR,intron-Distal3.5211212.41106HepG2HNRNPL
chr93463504034635093-3'-UTR,intron-Distal3.207234.50569K562GTF2F1
chr93463479634634844-3'-UTR,intron-Distal3.7926017.41715K562AGGF1
chr93463503434635092-3'-UTR,intron-Distal3.023583.09950HepG2IGF2BP3
chr93463475134634801-3'-UTR,intron-Distal5.3348534.27498K562HNRNPL
chr93463550834635613-3'-UTR,intron-Distal5.3355712.10389K562HNRNPL
chr93463474834634792-3'-UTR,intron-Distal5.4712931.29521HepG2HNRNPL
chr93463474934634792-3'-UTR,intron-Distal4.371655.00970HepG2IGF2BP3
chr93463563434635686-3'-UTR,CDS,intron-Distal3.267805.63550HepG2IGF2BP1
chr93463488234634933-3'-UTR,intron-Distal3.199433.07801K562UPF1
chr93463502434635121-3'-UTR,intron-Distal3.803035.58194HepG2HNRNPK
chr93463534034635426-3'-UTR,intron-Distal,intron-Proximal3.4655410.11039HepG2IGF2BP1
chr93463551534635634-3'-UTR,CDS,intron-Distal3.5450210.21169HepG2IGF2BP1
chr93463552634635553-3'-UTR,intron-Distal4.096445.43041K562AGGF1
chr93463550434635565-3'-UTR,intron-Distal4.8569211.47399HepG2LARP4
chr93463475134634796-3'-UTR,intron-Distal4.2871921.29810K562AGGF1
chr93463558434635644-3'-UTR,CDS,intron-Distal4.807717.21030HepG2UPF1
chr93463497234635088-3'-UTR,intron-Distal4.0116012.96325K562FAM120A
chr93463526134635349-3'-UTR,intron-Distal3.714893.92922HepG2AKAP1
chr93463482834634835-3'-UTR,intron-Distal3.4480317.38677HepG2HNRNPL
chr93463534034635416-3'-UTR,intron-Distal,intron-Proximal3.370188.91909K562AGGF1
chr93463503034635098-3'-UTR,intron-Distal5.193249.29441HepG2IGF2BP1
chr93463754334637625-5'-UTR,CDS,intron-Distal3.757985.23852K562DDX3X
chr93463735234637382-5'-UTR,CDS,intron-Distal4.6902320.55404HepG2DDX3X
chr93463769134637745-5'-UTR,CDS,intron-Distal,intron-Proximal5.0662165.83221HepG2DDX3X
chr93463759534637746-5'-UTR,CDS,intron-Distal,intron-Proximal4.226989.69624HepG2RPS3
chr93463774534637781-5'-UTR,intron-Distal,intron-Proximal5.0185026.47889HepG2DDX3X
chr93463699334637003-5'-UTR,CDS,intron-Distal,intron-Proximal4.415184.94988HepG2SND1
chr93463701134637055-5'-UTR,CDS,intron-Distal3.678983.57831HepG2SND1
chr93463757634637691-5'-UTR,CDS,intron-Distal,intron-Proximal5.81173400.00000HepG2DDX3X
chr93463764134637696-5'-UTR,CDS,intron-Distal,intron-Proximal4.752664.26442K562DDX3X
chr93463706634637216-5'-UTR,CDS,intron-Distal,intron-Proximal5.4872010.58731HepG2AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SIGMAR1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SIGMAR1 is not available on ENCORE database.

  • 93 RBPs can affect the levels of SIGMAR1.  








The Knockdown/knockout RNA-Seq assay for SIGMAR1 is not available on ENCORE database.





93 RBPs can affect the gene expression of SIGMAR1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SIGMAR1ENSG00000147955.121090.957901364.99250-0.323301.977301.44710HepG2ACO1
SIGMAR1ENSG00000147955.121385.175402255.14330-0.703207.269906.45220HepG2AKAP1
SIGMAR1ENSG00000147955.121499.209501975.76090-0.398206.315405.34610HepG2AUH
SIGMAR1ENSG00000147955.122854.555501926.734100.567007.605606.67420HepG2BOP1
SIGMAR1ENSG00000147955.121065.751401671.26820-0.6491011.037009.92080HepG2CELF1
SIGMAR1ENSG00000147955.122494.692801796.740400.4734012.9369011.53230HepG2DAZAP1
SIGMAR1ENSG00000147955.12866.225501090.09340-0.331602.646501.32030HepG2DDX52
SIGMAR1ENSG00000147955.121225.633702008.62770-0.712704.281003.07990HepG2DDX59
SIGMAR1ENSG00000147955.121330.115601855.86160-0.480503.611402.91370HepG2DDX6
SIGMAR1ENSG00000147955.121320.932001022.533000.369303.113702.07610HepG2DHX30
SIGMAR1ENSG00000147955.121935.356001305.845200.567509.649008.54140HepG2DKC1
SIGMAR1ENSG00000147955.121527.500101060.177900.526808.445807.27030HepG2DNAJC21
SIGMAR1ENSG00000147955.121637.247201300.555100.332002.299501.45710HepG2EEF2
SIGMAR1ENSG00000147955.121220.556301783.84030-0.547405.234204.43380HepG2EIF2S1
SIGMAR1ENSG00000147955.121487.870401772.83870-0.252802.478301.67760HepG2EIF4G1
SIGMAR1ENSG00000147955.12702.16700943.62570-0.426404.110202.65770HepG2FAM120A
SIGMAR1ENSG00000147955.121646.284802435.86620-0.565205.275404.24020HepG2FIP1L1
SIGMAR1ENSG00000147955.121255.767401739.42800-0.470005.398304.31070HepG2FUBP3
SIGMAR1ENSG00000147955.121546.454901989.25130-0.363302.723102.03760HepG2FXR1
SIGMAR1ENSG00000147955.121410.443701845.13410-0.387602.778502.11200HepG2G3BP1
SIGMAR1ENSG00000147955.122554.130002004.991400.349102.432301.82810HepG2GPKOW
SIGMAR1ENSG00000147955.121359.589101651.39250-0.280502.884501.93300HepG2HNRNPA2B1
SIGMAR1ENSG00000147955.121704.048001190.537900.517305.775804.80180HepG2HNRNPC
SIGMAR1ENSG00000147955.121252.122301868.80480-0.577706.673105.62310HepG2HNRNPK
SIGMAR1ENSG00000147955.122743.752501913.408900.519903.701002.98330HepG2HNRNPLL
SIGMAR1ENSG00000147955.123004.434602001.026700.586305.790304.90270HepG2MATR3
SIGMAR1ENSG00000147955.122052.352801696.671900.274501.986201.34730HepG2NSUN2
SIGMAR1ENSG00000147955.121684.42320773.261601.123103.799001.64030HepG2NUFIP2
SIGMAR1ENSG00000147955.12415.81340673.64200-0.696003.660802.62830HepG2PABPC1
SIGMAR1ENSG00000147955.121478.368001823.76240-0.302901.927201.31600HepG2PABPC4
SIGMAR1ENSG00000147955.121374.474201170.652400.231502.193901.43140HepG2PARN
SIGMAR1ENSG00000147955.12833.144401249.05430-0.584203.688802.49680HepG2PCBP2
SIGMAR1ENSG00000147955.121283.364501054.847000.282802.676701.94990HepG2PPIL4
SIGMAR1ENSG00000147955.12576.80770851.06370-0.561203.466702.57270HepG2PRPF8
SIGMAR1ENSG00000147955.121545.564701971.52330-0.351202.860702.30640HepG2PTBP1
SIGMAR1ENSG00000147955.122178.932101700.828200.357303.810203.12330HepG2PUF60
SIGMAR1ENSG00000147955.122020.001601390.286600.538907.057606.15060HepG2PUS1
SIGMAR1ENSG00000147955.121013.926302135.51880-1.0746013.7047012.46640HepG2QKI
SIGMAR1ENSG00000147955.12765.497901205.09300-0.654703.567702.76990HepG2RAVER1
SIGMAR1ENSG00000147955.121724.799802253.14990-0.385504.597003.52650HepG2RBM15
SIGMAR1ENSG00000147955.12942.460501896.01950-1.0085028.0378026.73150HepG2RBM22
SIGMAR1ENSG00000147955.121239.562801938.00330-0.644706.700905.69200HepG2RBM25
SIGMAR1ENSG00000147955.121618.760202194.23710-0.438803.388302.80200HepG2NELFE
SIGMAR1ENSG00000147955.121548.324902043.41420-0.400303.608002.91700HepG2RECQL
SIGMAR1ENSG00000147955.121123.62930740.174200.602104.201103.21460HepG2RPS3A
SIGMAR1ENSG00000147955.12521.42640841.82690-0.691104.536203.55970HepG2RRP9
SIGMAR1ENSG00000147955.121416.144701053.224400.427107.012906.05450HepG2SAFB2
SIGMAR1ENSG00000147955.121573.46710751.955301.065103.517601.94510HepG2SF1
SIGMAR1ENSG00000147955.121661.760702303.96340-0.471403.093002.37980HepG2SF3A3
SIGMAR1ENSG00000147955.121436.959501893.84190-0.398303.715702.90910HepG2SF3B1
SIGMAR1ENSG00000147955.121389.673802052.87140-0.562905.487204.70300HepG2SF3B4
SIGMAR1ENSG00000147955.121498.619401228.248700.286904.107103.34960HepG2SMN1
SIGMAR1ENSG00000147955.121475.03020672.247601.133604.175902.48810HepG2SNRNP200
SIGMAR1ENSG00000147955.121045.805902141.46940-1.0340041.3385039.99870HepG2SRFBP1
SIGMAR1ENSG00000147955.121459.109002142.64670-0.554305.253704.65520HepG2SRSF1
SIGMAR1ENSG00000147955.121216.104602037.93650-0.744807.316105.62360HepG2SRSF3
SIGMAR1ENSG00000147955.121099.124201743.06540-0.665307.195606.38000HepG2SRSF9
SIGMAR1ENSG00000147955.122345.490201859.276600.335005.428904.75770HepG2SSB
SIGMAR1ENSG00000147955.122982.607701507.224100.984606.065904.55040HepG2TBRG4
SIGMAR1ENSG00000147955.121232.700801769.67660-0.521703.883002.90130HepG2TIA1
SIGMAR1ENSG00000147955.121539.071801149.224500.421303.514702.96470HepG2TIAL1
SIGMAR1ENSG00000147955.121697.616901159.452700.5500011.1133010.09480HepG2TRIM56
SIGMAR1ENSG00000147955.122071.841001661.787200.318103.324902.36070HepG2TUFM
SIGMAR1ENSG00000147955.121116.713302083.45460-0.8997015.2041013.68510HepG2U2AF1
SIGMAR1ENSG00000147955.121350.123401759.07420-0.381702.041701.32830HepG2UBE2L3
SIGMAR1ENSG00000147955.122949.223102043.259500.5294014.1973012.84780HepG2UPF1
SIGMAR1ENSG00000147955.12408.775601182.79450-1.5328030.0309028.29950K562AQR
SIGMAR1ENSG00000147955.12611.98160777.25080-0.344903.031601.64840K562BCCIP
SIGMAR1ENSG00000147955.12567.380701076.09930-0.923407.541306.07360K562BOP1
SIGMAR1ENSG00000147955.12805.146901144.22340-0.507005.588204.48100K562CPSF6
SIGMAR1ENSG00000147955.121438.157602122.54730-0.561608.585706.90760K562CELF1
SIGMAR1ENSG00000147955.121227.192101660.46550-0.436207.020706.04900K562DDX47
SIGMAR1ENSG00000147955.12407.14890703.44650-0.788908.033306.40950K562EFTUD2
SIGMAR1ENSG00000147955.12422.04270753.06840-0.835407.469105.63360K562EIF3D
SIGMAR1ENSG00000147955.121280.396401726.35740-0.431105.687504.36260K562EIF4G2
SIGMAR1ENSG00000147955.12619.40480838.32520-0.436602.908401.74920K562FKBP4
SIGMAR1ENSG00000147955.12646.327201164.17920-0.8490011.565109.74640K562FMR1
SIGMAR1ENSG00000147955.12549.04740986.72910-0.845709.485807.68930K562FTO
SIGMAR1ENSG00000147955.12253.26330382.48870-0.594802.982102.24410K562G3BP2
SIGMAR1ENSG00000147955.12679.945001092.46870-0.684108.127106.76430K562GPKOW
SIGMAR1ENSG00000147955.12787.099001092.39010-0.472904.886403.47420K562HNRNPA1
SIGMAR1ENSG00000147955.12733.50570965.30610-0.396203.219402.58190K562HNRNPC
SIGMAR1ENSG00000147955.12576.52410932.78770-0.694205.253703.91340K562KRR1
SIGMAR1ENSG00000147955.12666.713101066.36420-0.677608.316606.74700K562METAP2
SIGMAR1ENSG00000147955.12942.789601327.58090-0.493807.890506.58880K562MTPAP
SIGMAR1ENSG00000147955.121252.017501475.12930-0.236603.024502.24780K562NSUN2
SIGMAR1ENSG00000147955.12304.91500489.10350-0.681705.408204.03090K562PCBP2
SIGMAR1ENSG00000147955.121067.960701398.01420-0.388502.769501.93820K562PCBP3
SIGMAR1ENSG00000147955.12432.99540684.53720-0.660805.596904.52890K562PRPF8
SIGMAR1ENSG00000147955.12790.68760534.110600.565905.954105.01240K562PTBP1
SIGMAR1ENSG00000147955.121485.588301883.60440-0.342502.568701.78350K562PUF60
SIGMAR1ENSG00000147955.12995.286101319.55640-0.406903.881301.97030K562RBM17
SIGMAR1ENSG00000147955.12260.07020362.90210-0.480702.805701.46760K562RBM25
SIGMAR1ENSG00000147955.121044.62860789.774800.403403.667802.52720K562RCC2
SIGMAR1ENSG00000147955.12761.96120574.891600.406302.298601.39700K562RPS3
SIGMAR1ENSG00000147955.121223.96810955.589100.357002.346801.35400K562SAFB
SIGMAR1ENSG00000147955.12903.451701455.47550-0.688009.169107.74990K562SF3A3
SIGMAR1ENSG00000147955.12507.214401038.91490-1.0344012.5475010.39910K562SF3B1
SIGMAR1ENSG00000147955.121000.33130748.674900.418002.856201.81040K562SRFBP1
SIGMAR1ENSG00000147955.121191.820301491.15700-0.323304.614303.44090K562SRPK2
SIGMAR1ENSG00000147955.12502.01070662.63780-0.400502.268001.35370K562SUPV3L1
SIGMAR1ENSG00000147955.121238.00990884.506700.485004.694903.38690K562TRIM56
SIGMAR1ENSG00000147955.12234.78160370.87270-0.659603.780202.46020K562U2AF1
SIGMAR1ENSG00000147955.12239.33610382.99260-0.678305.255304.15500K562U2AF2
SIGMAR1ENSG00000147955.12504.10240701.39160-0.476503.347402.22000K562UCHL5
SIGMAR1ENSG00000147955.121056.370801564.10550-0.5662010.126008.86260K562UPF1
SIGMAR1ENSG00000147955.12938.773201338.36440-0.511606.031604.71170K562WDR3
SIGMAR1ENSG00000147955.12935.164001391.68360-0.5735011.8669010.25890K562WDR43
SIGMAR1ENSG00000147955.12876.069901332.45840-0.605007.346205.82380K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SIGMAR1 is not available on ENCORE database.





8 RBPs can affect the splicing of SIGMAR1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESIGMAR1ENSG00000147955.12chr9-346369933463708634634718346358553463721634637729-0.057000.000580.00893excludedHepG2U2AF2
SESIGMAR1ENSG00000147955.12chr9-346369933463710934634718346358553463721634637417-0.065000.001290.05143excludedHepG2MATR3
SESIGMAR1ENSG00000147955.12chr9-346369933463708634634718346358553463721634637729-0.094000.007110.09107excludedK562HNRNPC
RISIGMAR1ENSG00000147955.12chr9-3463699334637417346369933463708634637216346374170.131000.000320.01110includedHepG2UCHL5
RISIGMAR1ENSG00000147955.12chr9-346369933463741734636993346370863463721634637417-0.051000.000220.04768excludedHepG2DKC1
RISIGMAR1ENSG00000147955.12chr9-346369933463741734636993346370863463721634637417-0.076000.000500.07320excludedHepG2NOL12
RISIGMAR1ENSG00000147955.12chr9-3463699334637417346369933463708634637216346374170.126000.000010.00025includedHepG2RBM22
RISIGMAR1ENSG00000147955.12chr9-3463699334637417346369933463708634637216346374170.186000.005240.04828includedK562EFTUD2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SIGMAR1 is not avaliable on ENCORE database.