PTPN3

General Information

Gene Name       : PTPN3
Gene ID             : ENSG00000070159.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PTPN3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PTPN3ENSG00000070159.130.230.160.20ENCSR000AEF
HepG2PTPN3ENSG00000070159.135.146.845.99ENCSR985KAT
K562PTPN3ENSG00000070159.130.000.000.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PTPN3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PTPN3 RNA is bound by 7 proteins.  







eCLIP assay for PTPN3 is not avaliable on ENCORE database.





7 proteins are bound to PTPN3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr9112199230112199251-CDS,intron-Distal,intron-Proximal4.554104.78529HepG2BCLAF1
chr9112200393112200420-CDS,intron-Distal,intron-Proximal4.310054.04372HepG2BCLAF1
chr9112200458112200537-CDS,intron-Distal,intron-Proximal3.346093.55754HepG2U2AF2
chr9112149029112149081-intron-Distal4.809027.59209HepG2SUGP2
chr9112149816112149851-intron-Distal4.379304.86548HepG2SUGP2
chr9112149181112149354-intron-Distal3.450764.84707HepG2HNRNPK
chr9112150332112150395-intron-Distal3.314625.35016HepG2SUGP2
chr9112148281112148344-intron-Distal4.028696.51675HepG2SUGP2
chr9112150852112150927-intron-Distal5.255978.94499HepG2SUGP2
chr9112148404112148465-intron-Distal5.111278.67089HepG2SUGP2
chr9112148708112148780-intron-Distal3.240577.25521HepG2SUGP2
chr9112148208112148281-intron-Distal5.093727.65425HepG2SUGP2
chr9112147517112147563-intron-Distal4.232044.51735HepG2QKI
chr9112150962112151036-intron-Distal3.614968.14948HepG2SUGP2
chr9112150551112150606-intron-Distal3.686935.56133HepG2SUGP2
chr9112260104112260283-intron-Distal4.355334.86859HepG2CSTF2T
chr9112149140112149211-intron-Distal3.373545.35016HepG2SUGP2
chr9112150625112150723-intron-Distal3.401678.75882HepG2SUGP2
chr9112219369112219434-intron-Distal,intron-Proximal3.106543.22368HepG2TIAL1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PTPN3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PTPN3 is not available on ENCORE database.

  • 90 RBPs can affect the levels of PTPN3.  








The Knockdown/knockout RNA-Seq assay for PTPN3 is not available on ENCORE database.





90 RBPs can affect the gene expression of PTPN3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PTPN3ENSG00000070159.9882.95930608.810400.536304.893903.50820HepG2AATF
PTPN3ENSG00000070159.9531.93280839.32850-0.658005.652104.35820HepG2ABCF1
PTPN3ENSG00000070159.91023.81410721.918000.503907.575706.67020HepG2ACO1
PTPN3ENSG00000070159.9483.65410670.37230-0.471003.263402.18580HepG2ADAR
PTPN3ENSG00000070159.91403.21590829.286800.758707.389606.56550HepG2AKAP1
PTPN3ENSG00000070159.91451.674801033.780900.489703.934102.69740HepG2AKAP8
PTPN3ENSG00000070159.9889.98750686.186800.375102.340601.61550HepG2ASCC1
PTPN3ENSG00000070159.91460.45260974.559200.5835010.880009.66840HepG2AUH
PTPN3ENSG00000070159.9488.17990660.51250-0.436202.314601.46010HepG2BCCIP
PTPN3ENSG00000070159.91135.91670718.047600.661607.612006.67960HepG2BOP1
PTPN3ENSG00000070159.9948.24560654.255700.535305.591504.54390HepG2CALR
PTPN3ENSG00000070159.9866.76590651.917700.410902.718501.95280HepG2CIRBP
PTPN3ENSG00000070159.9895.84350691.084700.374302.637701.55720HepG2CPSF7
PTPN3ENSG00000070159.9283.57110407.97900-0.524803.186802.03650HepG2CSTF2
PTPN3ENSG00000070159.91253.77640941.227300.413605.474904.62710HepG2CELF1
PTPN3ENSG00000070159.91160.803001011.957300.197902.014301.36650HepG2DAZAP1
PTPN3ENSG00000070159.91093.94110649.426400.752206.628705.49310HepG2DDX55
PTPN3ENSG00000070159.9513.30870693.88530-0.434902.887801.85530HepG2DDX5
PTPN3ENSG00000070159.91519.17890682.331701.1546016.2691014.93430HepG2DDX6
PTPN3ENSG00000070159.9483.32370690.65140-0.515005.428104.53730HepG2DKC1
PTPN3ENSG00000070159.9402.45200664.38910-0.723206.052704.73670HepG2EEF2
PTPN3ENSG00000070159.9836.33500618.468700.435302.466401.42680HepG2AGO1
PTPN3ENSG00000070159.91042.66880656.050200.668306.269705.39610HepG2EIF2S1
PTPN3ENSG00000070159.9483.41050634.18910-0.391702.734001.65870HepG2EIF3G
PTPN3ENSG00000070159.91202.27740705.852600.768206.149805.15380HepG2EIF4B
PTPN3ENSG00000070159.9713.76530956.42550-0.422203.050502.19630HepG2EIF4G2
PTPN3ENSG00000070159.9544.27600726.99360-0.417602.896001.77920HepG2ESF1
PTPN3ENSG00000070159.91326.542701118.951400.245402.346801.78540HepG2ETF1
PTPN3ENSG00000070159.9878.96420705.345100.317402.245801.49380HepG2EWSR1
PTPN3ENSG00000070159.91143.51800847.495100.432102.520101.78180HepG2FIP1L1
PTPN3ENSG00000070159.9394.59840660.33780-0.742802.729101.71980HepG2FTO
PTPN3ENSG00000070159.9697.34140432.405100.689406.589405.40620HepG2FUBP3
PTPN3ENSG00000070159.9929.80050731.401800.346202.075701.47260HepG2FXR1
PTPN3ENSG00000070159.9911.58170678.565700.425802.766202.10100HepG2G3BP1
PTPN3ENSG00000070159.9217.87440480.17450-1.1401012.5518010.74760HepG2GEMIN5
PTPN3ENSG00000070159.9557.66980747.25830-0.422202.426001.82230HepG2GPKOW
PTPN3ENSG00000070159.9984.81290689.158200.514907.417205.91390HepG2HDGF
PTPN3ENSG00000070159.9380.67940681.50410-0.840108.973207.90710HepG2HNRNPA1
PTPN3ENSG00000070159.91151.75660930.062700.308303.314202.30320HepG2HNRNPA2B1
PTPN3ENSG00000070159.9571.60100758.04370-0.407302.771402.07750HepG2HNRNPC
PTPN3ENSG00000070159.91068.03360686.914800.636706.494305.45470HepG2HNRNPK
PTPN3ENSG00000070159.91065.05310689.776800.626605.861904.91560HepG2IGF2BP2
PTPN3ENSG00000070159.9774.784301129.35780-0.543603.634802.68370HepG2LARP4
PTPN3ENSG00000070159.9530.13060709.78850-0.421002.699801.50530HepG2LIN28B
PTPN3ENSG00000070159.9514.20380731.65640-0.508803.459602.72450HepG2MAGOH
PTPN3ENSG00000070159.9496.99630735.77710-0.566003.719302.99810HepG2MATR3
PTPN3ENSG00000070159.9750.06170575.891900.381102.587401.41390HepG2NAA15
PTPN3ENSG00000070159.9460.17110753.12980-0.710705.869204.96370HepG2NCBP2
PTPN3ENSG00000070159.91397.139401003.459800.477406.424305.26580HepG2NOL12
PTPN3ENSG00000070159.9409.22040596.36990-0.543302.283601.30240HepG2NONO
PTPN3ENSG00000070159.91953.592301107.807700.818304.851003.64920HepG2PABPC1
PTPN3ENSG00000070159.9943.49330670.807300.492003.646802.82560HepG2PABPC4
PTPN3ENSG00000070159.9513.61470668.66080-0.380603.346602.50240HepG2PRPF4
PTPN3ENSG00000070159.9740.07580957.91600-0.372202.724302.13220HepG2PUF60
PTPN3ENSG00000070159.91175.188101016.900300.208602.242601.69680HepG2PUM1
PTPN3ENSG00000070159.91266.722501016.138700.317902.964002.26930HepG2PUM2
PTPN3ENSG00000070159.9581.57590735.30420-0.338403.166602.51730HepG2PUS1
PTPN3ENSG00000070159.91053.54440730.450000.528306.391505.49770HepG2QKI
PTPN3ENSG00000070159.91559.12440707.279201.140309.875408.59950HepG2RAVER1
PTPN3ENSG00000070159.91275.03960874.942200.543206.317905.08890HepG2RBM15
PTPN3ENSG00000070159.91105.94450935.230600.241801.969501.51260HepG2RBM22
PTPN3ENSG00000070159.9945.99520662.964200.512805.204204.30640HepG2RBM25
PTPN3ENSG00000070159.9590.25130815.03470-0.465503.144202.08350HepG2RBM27
PTPN3ENSG00000070159.9558.53100751.69610-0.428502.730401.93460HepG2RPS2
PTPN3ENSG00000070159.9635.541501217.49100-0.937909.247507.81770HepG2RPS3A
PTPN3ENSG00000070159.91050.56300495.542201.0840012.9453011.45150HepG2RRP9
PTPN3ENSG00000070159.9766.489101146.46180-0.580904.283802.66220HepG2SART3
PTPN3ENSG00000070159.9781.369201156.19820-0.565303.174401.51080HepG2SBDS
PTPN3ENSG00000070159.9501.52290736.00600-0.553403.345402.60220HepG2SF3A3
PTPN3ENSG00000070159.91534.64960705.848801.1204020.7230018.98710HepG2SF3B1
PTPN3ENSG00000070159.9715.60350918.55400-0.360203.839703.03410HepG2SLBP
PTPN3ENSG00000070159.9507.42960785.38120-0.630203.562702.67140HepG2SNRNP70
PTPN3ENSG00000070159.92848.711001056.298601.4312081.4452079.69850HepG2SRFBP1
PTPN3ENSG00000070159.91733.61930596.344701.5395071.9854069.96000HepG2SRSF9
PTPN3ENSG00000070159.9457.07490917.09990-1.0046021.9074020.76550HepG2SSB
PTPN3ENSG00000070159.9970.59700660.988500.554103.068801.79960HepG2SUB1
PTPN3ENSG00000070159.9903.73730572.173800.659307.426605.94520HepG2SUPT6H
PTPN3ENSG00000070159.9867.31900646.485800.423802.348601.71900HepG2SUPV3L1
PTPN3ENSG00000070159.9964.28530658.916400.549303.474502.85830HepG2TAF15
PTPN3ENSG00000070159.9625.076101101.55690-0.817403.974802.71260HepG2TBRG4
PTPN3ENSG00000070159.9945.69350605.363700.643508.260906.82310HepG2TIA1
PTPN3ENSG00000070159.9496.58000738.25160-0.572107.502706.65090HepG2TRIM56
PTPN3ENSG00000070159.9658.32700935.89260-0.507504.773203.59280HepG2TUFM
PTPN3ENSG00000070159.91031.00100724.913600.508104.028103.27600HepG2U2AF1
PTPN3ENSG00000070159.91394.14260990.660000.492803.901802.90020HepG2UBE2L3
PTPN3ENSG00000070159.9597.27060381.893500.645105.038404.00800HepG2UCHL5
PTPN3ENSG00000070159.9380.18110591.96150-0.638803.539702.39380HepG2UPF2
PTPN3ENSG00000070159.9780.311801090.54570-0.482902.793201.68990HepG2XPO5
PTPN3ENSG00000070159.91061.30440695.625900.609403.816902.32580HepG2XRCC5
PTPN3ENSG00000070159.9321.25420636.39460-0.986209.818008.47030HepG2XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PTPN3 is not available on ENCORE database.





3 RBPs can affect the splicing of PTPN3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPTPN3ENSG00000070159.9chr9-1121849971121851321121827031121828801121892291121894020.395000.001180.08964includedHepG2PRPF8
SEPTPN3ENSG00000070159.9chr9-1121849971121851321121827031121828801121892291121894020.419000.000010.00032includedHepG2HNRNPK
SEPTPN3ENSG00000070159.9chr9-112219452112219495112216775112216854112219571112219679-0.369000.000040.00220excludedHepG2SF3A3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PTPN3 is not avaliable on ENCORE database.