PTK2B

General Information

Gene Name       : PTK2B
Gene ID             : ENSG00000120899.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PTK2B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PTK2BENSG00000120899.1750.4495.7373.09ENCSR000AEF
HepG2PTK2BENSG00000120899.171.801.281.54ENCSR985KAT
K562PTK2BENSG00000120899.1725.7121.5823.64ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PTK2B is not avaliable on ENCORE database.



Proteins bound to RNA
  • PTK2B RNA is bound by 19 proteins.  







eCLIP assay for PTK2B is not avaliable on ENCORE database.





19 proteins are bound to PTK2B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr82731652427316598+3'-UTR4.630339.04751K562UPF1
chr82731646927316534+3'-UTR6.4407533.67477K562PUM2
chr82731653427316590+3'-UTR6.1683819.47388K562PUM2
chr82731675527316863+3'-UTR3.890719.11208K562MATR3
chr82731661627316650+3'-UTR4.067923.31330K562UPF1
chr82731675027316846+3'-UTR4.4195110.21863HepG2PTBP1
chr82731674827316863+3'-UTR4.6266174.77521K562PTBP1
chr82731647727316512+3'-UTR4.013063.01428K562UCHL5
chr82731646827316524+3'-UTR4.887625.24231K562UPF1
chr82731654427316665+3'-UTR3.128393.56007K562DDX6
chr82731653127316664+3'-UTR3.680139.75296K562DDX55
chr82728845327288532+5'-UTR,CDS3.110787.63960K562UCHL5
chr82728853327288581+5'-UTR,intron-Proximal3.649864.41130K562AQR
chr82728885227288975+5'-UTR,CDS,intron-Proximal4.3251921.76344K562DDX24
chr82728885427288937+5'-UTR,CDS,intron-Proximal3.6132410.34300K562SF3B4
chr82728859127288665+5'-UTR,intron-Distal,intron-Proximal3.508394.23459K562PRPF8
chr82728886127288897+5'-UTR,CDS,intron-Proximal4.919265.24929K562ZNF622
chr82728841727288468+5'-UTR,CDS3.548846.87242K562DDX24
chr82728863927288680+5'-UTR,intron-Distal3.047453.01994K562BUD13
chr82718316627183195+5'-UTR4.331784.42734K562UCHL5
chr82728839127288417+5'-UTR,CDS,intron-Proximal4.189485.20093K562DDX24
chr82729691427296943+CDS,intron-Proximal3.540077.16774K562AQR
chr82729499627295013+CDS3.168015.44868K562ZNF622
chr82729494727295014+CDS,intron-Proximal3.8449510.52099K562DDX24
chr82729528027295373+CDS,intron-Proximal3.003889.79455K562ZNF622
chr82730835827308383+CDS3.831783.01428K562UCHL5
chr82729463927294700+CDS3.051115.41277K562UCHL5
chr82727741127277437+CDS,intron-Proximal4.419195.23082K562DDX24
chr82729326727293351+CDS,intron-Proximal5.603319.95272K562AQR
chr82730900727309083+CDS,intron-Proximal4.704435.70555K562PRPF8
chr82729527927295344+CDS,intron-Proximal4.8038914.63362K562DDX24
chr82729497827295015+CDS,intron-Proximal3.231776.02234K562UCHL5
chr82729458827294648+CDS,intron-Proximal4.203226.10653K562SF3B4
chr82731209827312130+CDS,intron-Proximal3.059624.30396K562UCHL5
chr82728789327287933+CDS4.863217.50842K562DDX24
chr82729528027295380+CDS,intron-Proximal4.599066.94434K562GRWD1
chr82727741127277516+CDS,intron-Proximal3.003656.26074K562UCHL5
chr82730820427308309+CDS,intron-Proximal3.824686.71722K562SF3B4
chr82727982027279883+CDS,intron-Proximal4.192698.55862K562DDX24
chr82729106727291176+CDS,intron-Distal,intron-Proximal3.681377.22920K562AQR
chr82729795727298022+CDS,intron-Proximal4.3509110.30697K562AQR
chr82728976927289799+CDS,intron-Proximal3.284413.01994K562BUD13
chr82727746027277501+CDS4.123453.70678K562BUD13
chr82729095027291003+CDS,intron-Proximal4.746076.08900K562BUD13
chr82730035227300406+CDS,intron-Proximal3.911646.79537K562AQR
chr82729527827295319+CDS,intron-Proximal3.453026.02234K562UCHL5
chr82730902727309120+CDS,intron-Proximal3.092936.19808K562AQR
chr82730167227301727+CDS,intron-Proximal5.283457.81477K562SF3B4
chr82728981727289879+CDS,intron-Proximal5.066929.94700K562DDX24
chr82729095127290992+CDS,intron-Proximal5.863218.32974K562DDX24
chr82729768227297782+CDS,intron-Proximal4.3854114.68530K562AQR
chr82726255927262614+intron-Distal4.961843.55787K562PTBP1
chr82726140027261442+intron-Distal4.685563.92866K562PTBP1
chr82725464727254809+intron-Distal4.135804.67922K562PTBP1
chr82723614327236210+intron-Distal4.078863.22972K562TARDBP
chr82730344727303549+intron-Distal,intron-Proximal5.185529.48346K562RBFOX2
chr82718374927183820+intron-Distal4.086753.69425K562TARDBP
chr82730415927304263+intron-Distal4.955957.30165K562QKI
chr82718347227183520+intron-Distal4.440734.19739K562EIF4G2
chr82718444527184501+intron-Distal,intron-Proximal4.067423.31153K562GTF2F1
chr82723564127235718+intron-Distal3.804148.52685K562PTBP1
chr82726144227261536+intron-Distal5.7174114.79190K562PTBP1
chr82729697827297028+intron-Distal,intron-Proximal4.116076.01372K562AQR
chr82729207727292159+intron-Proximal4.458623.89565K562PRPF8
chr82729694327296961+intron-Proximal4.530167.53589K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PTK2B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PTK2B is not available on ENCORE database.

  • 110 RBPs can affect the levels of PTK2B.  








The Knockdown/knockout RNA-Seq assay for PTK2B is not available on ENCORE database.





110 RBPs can affect the gene expression of PTK2B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PTK2BENSG00000120899.13398.55250164.250401.278809.227307.66700HepG2ABCF1
PTK2BENSG00000120899.13235.88350125.765700.907205.069804.29020HepG2BOP1
PTK2BENSG00000120899.13306.80020150.632201.026206.138704.65330HepG2CCAR1
PTK2BENSG00000120899.13268.96410178.892700.588202.662601.90360HepG2CIRBP
PTK2BENSG00000120899.13189.36070118.047000.681702.202201.52510HepG2CNOT7
PTK2BENSG00000120899.13163.6261086.409100.921004.656903.33840HepG2YBX3
PTK2BENSG00000120899.13136.3613078.738500.792203.071001.94110HepG2CSTF2
PTK2BENSG00000120899.13356.80540190.944000.901905.216804.24520HepG2DAZAP1
PTK2BENSG00000120899.13252.48940144.524300.804804.609203.75900HepG2DDX21
PTK2BENSG00000120899.13210.21600141.557200.570402.472701.61260HepG2DDX24
PTK2BENSG00000120899.13234.43190117.250800.999504.422502.84570HepG2DDX27
PTK2BENSG00000120899.13152.8824081.829600.901604.052802.88100HepG2DHX30
PTK2BENSG00000120899.13289.53280158.341100.870606.561005.60260HepG2DKC1
PTK2BENSG00000120899.13185.4109084.838401.127807.140406.05340HepG2DNAJC21
PTK2BENSG00000120899.13314.77420180.016600.806104.785404.01770HepG2EIF2S1
PTK2BENSG00000120899.13452.51200198.935101.1856010.693809.46260HepG2EIF4A3
PTK2BENSG00000120899.13310.32950180.475600.781903.085102.22660HepG2EIF4G2
PTK2BENSG00000120899.13294.73390142.196801.051405.131103.68670HepG2ESF1
PTK2BENSG00000120899.13534.06850267.813100.9957012.9284011.78720HepG2ETF1
PTK2BENSG00000120899.1349.91280165.82570-1.732204.680503.70010HepG2FIP1L1
PTK2BENSG00000120899.13340.71840115.666501.558507.349905.70520HepG2FTO
PTK2BENSG00000120899.13268.49570186.200000.527902.248101.64490HepG2G3BP1
PTK2BENSG00000120899.13320.26960197.684300.696003.888002.82090HepG2G3BP2
PTK2BENSG00000120899.13679.38170130.851202.3762040.0907038.00620HepG2GPKOW
PTK2BENSG00000120899.13315.4478085.651301.8808019.4350017.97650HepG2HNRNPA1
PTK2BENSG00000120899.13285.3149095.275501.5823013.2045011.79510HepG2HNRNPC
PTK2BENSG00000120899.13239.96910146.333500.713504.263503.39400HepG2HNRNPF
PTK2BENSG00000120899.13337.55020124.875701.4345012.5053011.29260HepG2HNRNPLL
PTK2BENSG00000120899.13196.3494094.645301.052707.021006.09110HepG2HNRNPU
PTK2BENSG00000120899.13308.19730144.095601.096709.522308.25400HepG2IGF2BP1
PTK2BENSG00000120899.13386.23350189.265701.029008.210307.11150HepG2IGF2BP2
PTK2BENSG00000120899.13224.0910096.676301.212705.669404.65200HepG2ILF2
PTK2BENSG00000120899.13221.40230115.073700.944004.406502.71350HepG2ILF3
PTK2BENSG00000120899.13214.51750151.279500.503802.500701.52980HepG2KIF1C
PTK2BENSG00000120899.13256.56740159.063600.689603.079002.20000HepG2LARP4
PTK2BENSG00000120899.13301.43250127.405701.242307.153605.55830HepG2MTPAP
PTK2BENSG00000120899.13179.04930112.622000.668802.552101.38610HepG2NAA15
PTK2BENSG00000120899.13313.64090206.677000.601602.855602.21280HepG2NCBP2
PTK2BENSG00000120899.13251.33280110.742401.182304.698403.73260HepG2NSUN2
PTK2BENSG00000120899.13321.08920184.051200.802804.985004.02620HepG2PABPC4
PTK2BENSG00000120899.13252.84070170.978700.564302.923902.30290HepG2PCBP1
PTK2BENSG00000120899.13142.8906084.415300.759203.252202.45880HepG2PPIL4
PTK2BENSG00000120899.13398.98480180.751901.1422011.8505010.73580HepG2PUF60
PTK2BENSG00000120899.13224.67560168.578700.414301.887201.35840HepG2PUS1
PTK2BENSG00000120899.13371.10700188.444600.977608.342607.34600HepG2QKI
PTK2BENSG00000120899.1364.62910144.43010-1.160103.815502.99220HepG2RAVER1
PTK2BENSG00000120899.13219.06400119.715000.871602.982401.88080HepG2RCC2
PTK2BENSG00000120899.13330.15220193.613700.769903.640503.03700HepG2NELFE
PTK2BENSG00000120899.13525.94790157.654601.7381025.2997023.66940HepG2RPLP0
PTK2BENSG00000120899.13290.90140141.914101.035405.916404.56550HepG2RPS10
PTK2BENSG00000120899.13229.83390113.209701.021506.207005.32760HepG2RPS19
PTK2BENSG00000120899.13313.33640135.955801.204508.796407.43160HepG2RPS2
PTK2BENSG00000120899.13225.37720118.488100.927504.475503.45940HepG2RPS3A
PTK2BENSG00000120899.13167.5709084.283300.991405.603604.73960HepG2SAFB2
PTK2BENSG00000120899.13386.01120145.450901.408004.601102.75180HepG2SF1
PTK2BENSG00000120899.13144.82580260.64910-0.847804.467803.60030HepG2SF3A3
PTK2BENSG00000120899.13265.34370123.589401.102207.316806.21770HepG2SF3B1
PTK2BENSG00000120899.13338.31980181.149200.901104.115703.41780HepG2SF3B4
PTK2BENSG00000120899.13246.16250173.334300.506002.851502.13940HepG2SLBP
PTK2BENSG00000120899.13224.57770137.519500.707502.396301.67120HepG2SNRNP70
PTK2BENSG00000120899.13263.89010133.019200.988205.143503.74050HepG2SRSF3
PTK2BENSG00000120899.13259.67400143.771900.852806.114205.14400HepG2SRSF7
PTK2BENSG00000120899.13657.78470219.496201.5833035.9203034.55610HepG2SSB
PTK2BENSG00000120899.13274.56460202.968700.435802.368501.78490HepG2SUCLG1
PTK2BENSG00000120899.13237.10400124.738300.926504.644903.80290HepG2SUPV3L1
PTK2BENSG00000120899.13248.38420121.774301.028306.285405.25300HepG2TARDBP
PTK2BENSG00000120899.13379.73140194.388700.965904.126102.84090HepG2TBRG4
PTK2BENSG00000120899.13398.6332091.949602.1160032.6210031.24700HepG2TIAL1
PTK2BENSG00000120899.13155.4795092.788800.744603.476202.85970HepG2TRIM56
PTK2BENSG00000120899.1346.75550151.21420-1.693404.262703.02500HepG2U2AF2
PTK2BENSG00000120899.13288.56520186.943700.626202.441401.65890HepG2UBE2L3
PTK2BENSG00000120899.13314.42950231.155100.443801.946301.34330HepG2UPF1
PTK2BENSG00000120899.13193.72550114.251800.761702.851301.83220HepG2UPF2
PTK2BENSG00000120899.13138.71100223.17240-0.686103.567902.90330HepG2UTP3
PTK2BENSG00000120899.13170.25490106.127400.681802.497201.46300HepG2XPO5
PTK2BENSG00000120899.13296.05790122.790901.269609.011807.72080HepG2XRN2
PTK2BENSG00000120899.132071.615602515.60170-0.280102.209001.34130K562AKAP8
PTK2BENSG00000120899.132984.843402382.119700.325303.084202.39380K562AKAP8L
PTK2BENSG00000120899.131747.757703368.40150-0.9466019.1257017.74820K562AQR
PTK2BENSG00000120899.132094.861402499.42190-0.254702.312401.48490K562ATP5C1
PTK2BENSG00000120899.132379.755701914.456000.313805.083003.76470K562BCLAF1
PTK2BENSG00000120899.132749.424601703.216800.690806.694704.75540K562CIRBP
PTK2BENSG00000120899.135988.578103607.942500.730905.330303.79580K562CNOT7
PTK2BENSG00000120899.131842.770601452.399600.343304.199102.86140K562CSTF2
PTK2BENSG00000120899.135680.793104797.545300.243702.695401.73350K562CELF1
PTK2BENSG00000120899.132413.566103098.45970-0.360406.442205.50600K562DDX47
PTK2BENSG00000120899.132599.399601827.169500.508504.543402.40320K562DDX51
PTK2BENSG00000120899.131927.588802563.31510-0.411206.383604.96920K562DKC1
PTK2BENSG00000120899.132467.900601750.384200.495503.346001.93200K562EEF2
PTK2BENSG00000120899.132218.845601690.876000.391902.586001.70660K562EFTUD2
PTK2BENSG00000120899.131544.521302503.65220-0.696906.767305.71570K562EIF2S2
PTK2BENSG00000120899.13996.848101575.96580-0.660804.067802.82110K562EIF3A
PTK2BENSG00000120899.13868.065701661.15610-0.9363016.7489014.59660K562EIF4A3
PTK2BENSG00000120899.131945.696601495.973200.379104.933403.32680K562EIF4B
PTK2BENSG00000120899.132679.730202090.285700.358303.348502.40830K562FIP1L1
PTK2BENSG00000120899.131147.056901727.53460-0.5908010.948309.83100K562FXR1
PTK2BENSG00000120899.13383.72200955.49750-1.316209.941208.44190K562G3BP2
PTK2BENSG00000120899.133616.768802667.698800.439007.793105.95440K562GLRX3
PTK2BENSG00000120899.133558.430902356.569000.594509.238107.78000K562GPKOW
PTK2BENSG00000120899.131974.469103335.97090-0.756607.043205.82780K562GRSF1
PTK2BENSG00000120899.132210.930301667.354400.407004.419802.93540K562HNRNPF
PTK2BENSG00000120899.132026.768402800.09080-0.466306.117604.48390K562HNRNPL
PTK2BENSG00000120899.131182.051601719.31890-0.540504.832503.56340K562HNRNPM
PTK2BENSG00000120899.133329.995902814.629900.242502.662801.78650K562HNRNPU
PTK2BENSG00000120899.131426.468902833.94280-0.9904019.8713017.89170K562HSPD1
PTK2BENSG00000120899.132760.506601590.294200.795506.877204.96850K562IGF2BP2
PTK2BENSG00000120899.13905.256101670.19320-0.883606.612905.28620K562MAGOH
PTK2BENSG00000120899.135420.404604158.756700.382104.012702.65330K562MSI2
PTK2BENSG00000120899.132456.375502804.75060-0.191302.218801.49100K562MTPAP
PTK2BENSG00000120899.133721.803703116.255700.256105.859404.83070K562NSUN2
PTK2BENSG00000120899.134837.867603466.170900.480902.924001.65200K562PABPC1
PTK2BENSG00000120899.132972.005004009.08590-0.431805.369103.46160K562PNPT1
PTK2BENSG00000120899.131068.952001645.43160-0.622304.382903.44020K562PRPF8
PTK2BENSG00000120899.133281.524104256.98590-0.375504.267003.26020K562PUF60
PTK2BENSG00000120899.133255.938004528.12260-0.475808.432206.48450K562PUM1
PTK2BENSG00000120899.133319.924304436.51030-0.418308.029506.36730K562PUM2
PTK2BENSG00000120899.132791.480502301.809100.278203.269902.63370K562RBM15
PTK2BENSG00000120899.132017.239801527.583600.401004.617603.33220K562RCC2
PTK2BENSG00000120899.13958.461901675.64250-0.805906.648305.37320K562RPS19
PTK2BENSG00000120899.131274.008102173.86730-0.770903.041001.75940K562SF1
PTK2BENSG00000120899.133800.477803075.059300.305504.655303.62070K562SF3A3
PTK2BENSG00000120899.13779.903701012.39910-0.376403.912202.34970K562SSB
PTK2BENSG00000120899.132060.202002742.54440-0.412704.046002.38220K562SSRP1
PTK2BENSG00000120899.131757.480502985.78740-0.764603.498301.83000K562SUPT6H
PTK2BENSG00000120899.132174.189101592.391900.449202.511201.54820K562SUPV3L1
PTK2BENSG00000120899.131345.784102529.06270-0.9102022.5309020.33110K562SYNCRIP
PTK2BENSG00000120899.132172.995901609.915700.432602.217401.58010K562TARDBP
PTK2BENSG00000120899.132293.649101609.933500.510504.942703.65810K562TIAL1
PTK2BENSG00000120899.132203.820201524.627400.531404.918303.38700K562TRA2A
PTK2BENSG00000120899.132292.132601710.787500.421902.777001.82870K562TRIM56
PTK2BENSG00000120899.134554.910003615.105800.333306.204804.27580K562TROVE2
PTK2BENSG00000120899.13464.41240925.52280-0.9949011.577009.14910K562U2AF1
PTK2BENSG00000120899.13541.20650956.08110-0.821009.872908.35300K562U2AF2
PTK2BENSG00000120899.132410.662601685.721700.516005.104503.67840K562UCHL5
PTK2BENSG00000120899.132847.776303304.23780-0.214502.853202.12330K562UPF1
PTK2BENSG00000120899.132100.838002697.77940-0.360803.942501.92600K562UPF2
PTK2BENSG00000120899.132067.699003235.72580-0.646107.363405.45080K562UTP3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PTK2B is not available on ENCORE database.





9 RBPs can affect the splicing of PTK2B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPTK2BENSG00000120899.13chr8+273033102730343627301722273017882730826527308412-0.239000.000010.00117excludedK562PRPF8
SEPTK2BENSG00000120899.13chr8+273033102730343627301722273017882730826527308412-0.224000.000000.00254excludedK562RBFOX2
SEPTK2BENSG00000120899.13chr8+273033102730343627301722273017882730826527308412-0.119000.000560.05020excludedK562XRCC6
SEPTK2BENSG00000120899.13chr8+273033102730343627301722273017882730826527308412-0.065000.003230.04440excludedK562PUS1
SEPTK2BENSG00000120899.13chr8+273033102730343627301722273017882730826527308412-0.085000.000250.05008excludedK562MTPAP
SEPTK2BENSG00000120899.13chr8+2730331027303436273017222730178827308265273084120.086000.000100.02539includedK562LARP4
SEPTK2BENSG00000120899.13chr8+273033102730343627301722273017882730826527308412-0.400000.000000.00000excludedK562TARDBP
SEPTK2BENSG00000120899.13chr8+273033102730343627301722273017882730826527308412-0.538000.000000.00000excludedK562HNRNPK
SEPTK2BENSG00000120899.13chr8+2718078327180943271799182718001627183080271831980.613000.005210.07149includedK562HNRNPC
SEPTK2BENSG00000120899.13chr8+272977532729795827296825272969152730039127300500-0.132000.000000.00002excludedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PTK2B is not avaliable on ENCORE database.