PSMB6

General Information

Gene Name       : PSMB6
Gene ID             : ENSG00000142507.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PSMB6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PSMB6ENSG00000142507.990.24140.59115.41ENCSR000AEF
HepG2PSMB6ENSG00000142507.9246.46211.04228.75ENCSR985KAT
K562PSMB6ENSG00000142507.9195.09164.72179.91ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PSMB6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PSMB6 RNA is bound by 11 proteins.  







eCLIP assay for PSMB6 is not avaliable on ENCORE database.





11 proteins are bound to PSMB6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1747013954701430+3'-UTR,CDS4.515705.23727HepG2G3BP1
chr1747016644701739+3'-UTR,CDS5.3343819.22875HepG2LARP4
chr1747013184701381+3'-UTR,CDS3.735093.14078HepG2GRSF1
chr1747010664701098+3'-UTR,CDS4.691545.41965HepG2G3BP1
chr1747016614701720+3'-UTR,CDS4.876636.59389HepG2G3BP1
chr1747017364701774+3'-UTR,polyA_signal5.6729211.15381K562PABPC4
chr1747010904701107+3'-UTR,CDS,intron-Proximal4.973579.22045K562LIN28B
chr1747015994701661+3'-UTR,CDS3.318505.99947HepG2G3BP1
chr1747013034701366+3'-UTR,CDS,intron-Proximal4.601728.90122K562RPS3
chr1747013024701344+3'-UTR,CDS,intron-Proximal4.8703416.96193K562LIN28B
chr1747015754701664+3'-UTR,CDS4.0406413.10389HepG2LARP4
chr1747013024701341+3'-UTR,CDS,intron-Proximal4.211346.88279HepG2LIN28B
chr1747010464701069+3'-UTR,CDS3.308743.81620HepG2LARP4
chr1747013194701349+3'-UTR,CDS3.867993.08171K562APOBEC3C
chr1747013124701421+3'-UTR,CDS4.1123314.82699HepG2LARP4
chr1746994714699592+5'-UTR,CDS,intron-Proximal3.9852221.99127K562DDX3X
chr1747008594700905+CDS,intron-Proximal5.072517.36776HepG2PRPF8
chr1747000394700086+CDS4.390179.36586K562LIN28B
chr1747000704700160+CDS,intron-Proximal5.371336.75320K562AQR
chr1747009784700999+CDS,intron-Proximal3.634623.01531K562YBX3
chr1746995014699544+CDS3.534035.15615HepG2RPS3
chr1747000224700086+CDS,intron-Proximal4.238097.67223HepG2G3BP1
chr1747007684700842+CDS3.072976.56754K562YBX3
chr1747000314700086+CDS3.830327.61854HepG2RPS3
chr1746995604699589+CDS3.376634.04629HepG2G3BP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PSMB6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PSMB6 is not available on ENCORE database.

  • 93 RBPs can affect the levels of PSMB6.  








The Knockdown/knockout RNA-Seq assay for PSMB6 is not available on ENCORE database.





93 RBPs can affect the gene expression of PSMB6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PSMB6ENSG00000142507.53008.466902379.732400.338102.168201.69080HepG2AKAP1
PSMB6ENSG00000142507.52134.411902747.65220-0.364406.178405.21680HepG2AUH
PSMB6ENSG00000142507.51167.434001509.24170-0.370502.626501.74830HepG2BCLAF1
PSMB6ENSG00000142507.51002.369801277.95260-0.350403.053701.75940HepG2BUD13
PSMB6ENSG00000142507.52621.922101870.665400.487004.876003.86480HepG2CIRBP
PSMB6ENSG00000142507.51150.646001532.01280-0.413007.335606.34880HepG2CKAP4
PSMB6ENSG00000142507.53160.851502279.441000.471504.401003.62610HepG2DDX3X
PSMB6ENSG00000142507.5642.610901024.92220-0.673507.124705.10110HepG2DDX52
PSMB6ENSG00000142507.51094.599101374.83020-0.328904.769103.95040HepG2DNAJC2
PSMB6ENSG00000142507.51400.916301882.34460-0.426203.511602.84800HepG2EIF2S1
PSMB6ENSG00000142507.51576.526802025.55020-0.361601.955401.37010HepG2EIF4B
PSMB6ENSG00000142507.51940.565602371.84390-0.289503.970903.00010HepG2EIF4G1
PSMB6ENSG00000142507.51824.158702272.06800-0.316802.516501.73800HepG2EIF4G2
PSMB6ENSG00000142507.51061.792701477.60330-0.476804.637003.26150HepG2ESF1
PSMB6ENSG00000142507.51108.938301421.52100-0.358302.723701.46640HepG2FKBP4
PSMB6ENSG00000142507.51256.623201583.93070-0.334002.981102.16730HepG2FUBP3
PSMB6ENSG00000142507.51646.563602067.41430-0.328402.417801.58630HepG2G3BP2
PSMB6ENSG00000142507.51900.446602209.47100-0.217402.291901.43310HepG2HNRNPA2B1
PSMB6ENSG00000142507.51636.225502042.12560-0.319704.458203.57210HepG2HNRNPF
PSMB6ENSG00000142507.52467.717901972.236900.323202.624801.94300HepG2HNRNPK
PSMB6ENSG00000142507.51236.606001547.36500-0.323404.267203.52760HepG2HNRNPU
PSMB6ENSG00000142507.51445.058301990.74960-0.462203.119902.04650HepG2KHSRP
PSMB6ENSG00000142507.5751.313501400.82150-0.8988024.8603022.24650HepG2KIF1C
PSMB6ENSG00000142507.51575.086002111.61560-0.422903.128202.46090HepG2MATR3
PSMB6ENSG00000142507.5779.587601071.75220-0.459202.281201.40700HepG2MTPAP
PSMB6ENSG00000142507.5909.987401170.51550-0.363202.942501.68840HepG2NAA15
PSMB6ENSG00000142507.51837.617502383.91740-0.375504.902503.89100HepG2NOL12
PSMB6ENSG00000142507.5718.60610996.31660-0.471402.088801.33400HepG2PABPC1
PSMB6ENSG00000142507.51342.487701924.42510-0.519504.828603.88640HepG2PABPC4
PSMB6ENSG00000142507.51556.878502064.28460-0.407007.015306.12130HepG2PCBP1
PSMB6ENSG00000142507.51206.297501505.18230-0.319403.219902.39150HepG2PRPF4
PSMB6ENSG00000142507.51011.837701317.23260-0.380502.844202.02380HepG2PRPF8
PSMB6ENSG00000142507.51458.859402100.49610-0.5259010.374309.44590HepG2PTBP1
PSMB6ENSG00000142507.52113.559202415.73780-0.192802.524001.95210HepG2PUM1
PSMB6ENSG00000142507.51341.131602274.86930-0.7623017.0716015.71100HepG2QKI
PSMB6ENSG00000142507.5741.813201356.10850-0.870305.933004.92740HepG2RAVER1
PSMB6ENSG00000142507.52114.466902636.74540-0.318501.931501.47810HepG2RBM22
PSMB6ENSG00000142507.51329.825102064.59760-0.634609.937308.71630HepG2RBM25
PSMB6ENSG00000142507.51656.279302337.64280-0.497108.362307.51370HepG2NELFE
PSMB6ENSG00000142507.51506.011702177.21060-0.5317011.2662010.15170HepG2RECQL
PSMB6ENSG00000142507.5922.144001302.98740-0.498803.998703.07530HepG2RRP9
PSMB6ENSG00000142507.52308.083401483.381300.637702.955702.25800HepG2SF3A3
PSMB6ENSG00000142507.51506.890602186.87090-0.5373011.4136010.34060HepG2SF3B4
PSMB6ENSG00000142507.51842.613602182.04110-0.243903.452802.68340HepG2SLBP
PSMB6ENSG00000142507.51883.669201606.986800.229103.224002.53820HepG2SMN1
PSMB6ENSG00000142507.52410.091402978.09330-0.305305.548104.90600HepG2SRFBP1
PSMB6ENSG00000142507.51914.010702246.90900-0.231302.648402.03290HepG2SRSF5
PSMB6ENSG00000142507.51673.182802006.31900-0.262003.167902.42860HepG2SRSF7
PSMB6ENSG00000142507.51313.468201857.04420-0.4996010.119709.18020HepG2SRSF9
PSMB6ENSG00000142507.51997.750402585.66650-0.372206.978406.23490HepG2SSB
PSMB6ENSG00000142507.51585.737302051.73270-0.371704.843304.13420HepG2TAF15
PSMB6ENSG00000142507.51341.167701885.24280-0.491306.535605.25670HepG2TIA1
PSMB6ENSG00000142507.51687.371802353.29610-0.479903.950202.94040HepG2UBE2L3
PSMB6ENSG00000142507.5773.764501004.25750-0.376202.671301.92460HepG2UCHL5
PSMB6ENSG00000142507.51060.099801315.53480-0.311403.773402.97770HepG2UPF1
PSMB6ENSG00000142507.51509.585001270.093500.249102.688102.09780HepG2UTP3
PSMB6ENSG00000142507.5940.166801334.35600-0.505202.513001.31990HepG2XRCC5
PSMB6ENSG00000142507.52604.225101446.833100.8479037.6605036.24510HepG2ZNF622
PSMB6ENSG00000142507.52335.054601466.009300.6715018.1062016.77680K562AGGF1
PSMB6ENSG00000142507.52297.412601610.959500.512006.493904.82660K562AKAP8
PSMB6ENSG00000142507.52220.744901525.458200.541707.052205.96880K562AKAP8L
PSMB6ENSG00000142507.5622.62230929.01410-0.577305.385803.80280K562CCAR1
PSMB6ENSG00000142507.52066.443901754.141600.236302.725502.07850K562DDX47
PSMB6ENSG00000142507.52041.623601641.445400.314704.085102.99120K562DKC1
PSMB6ENSG00000142507.51714.792102019.91740-0.236302.497601.80810K562EIF2S2
PSMB6ENSG00000142507.51137.79400779.777800.545007.342906.05810K562EIF3G
PSMB6ENSG00000142507.51464.729901048.854500.481705.053203.94190K562EIF4A3
PSMB6ENSG00000142507.51238.45090915.555600.435704.852603.04940K562EWSR1
PSMB6ENSG00000142507.51599.902701128.582500.503402.053401.31950K562FIP1L1
PSMB6ENSG00000142507.5698.51870941.76580-0.431102.934901.76980K562FKBP4
PSMB6ENSG00000142507.51662.704501090.767900.608105.980305.14060K562FXR1
PSMB6ENSG00000142507.5247.94430732.42500-1.5627016.9895014.86340K562G3BP2
PSMB6ENSG00000142507.53235.376802691.588900.265402.344101.64550K562GRSF1
PSMB6ENSG00000142507.51592.806301924.45700-0.272902.383901.39080K562HNRNPA1
PSMB6ENSG00000142507.5815.722901084.90340-0.411403.543802.87870K562HNRNPC
PSMB6ENSG00000142507.51721.49680928.456700.890707.681406.00530K562HNRNPM
PSMB6ENSG00000142507.51758.369302131.22840-0.277402.959502.03610K562HNRNPU
PSMB6ENSG00000142507.52563.272503242.76770-0.339204.112001.72700K562CCAR2
PSMB6ENSG00000142507.51327.969201618.86060-0.285802.166801.44770K562KIF1C
PSMB6ENSG00000142507.51333.924901050.481200.344502.781401.38910K562LARP7
PSMB6ENSG00000142507.51673.661701153.925400.536406.663405.33230K562MAGOH
PSMB6ENSG00000142507.52135.794001813.537200.235902.083201.31020K562MBNL1
PSMB6ENSG00000142507.52424.513503000.53750-0.307502.634801.53550K562MSI2
PSMB6ENSG00000142507.52173.614801220.303000.832804.682603.30150K562PABPN1
PSMB6ENSG00000142507.51535.863402138.12460-0.477304.172803.14980K562PCBP3
PSMB6ENSG00000142507.52085.073201281.426100.702203.018502.15710K562PPIG
PSMB6ENSG00000142507.52142.429801271.662600.7524010.687209.20060K562PRPF8
PSMB6ENSG00000142507.51293.67220972.719500.411303.464102.43740K562PSIP1
PSMB6ENSG00000142507.51703.360201121.164900.603309.007007.85350K562PTBP1
PSMB6ENSG00000142507.52685.629603200.93630-0.253203.115402.09920K562PUM2
PSMB6ENSG00000142507.53106.408701512.771201.0380021.2804019.80070K562PUS1
PSMB6ENSG00000142507.51989.244301474.021300.432406.288405.41920K562RBM15
PSMB6ENSG00000142507.51099.69090761.176600.530704.652403.53320K562SF3B4
PSMB6ENSG00000142507.51984.583301281.592500.630802.592101.42000K562SNRNP200
PSMB6ENSG00000142507.51397.918501615.70510-0.208902.266601.41070K562SRPK2
PSMB6ENSG00000142507.51644.988701099.196600.581505.308204.33500K562SRSF1
PSMB6ENSG00000142507.51454.251401866.75800-0.360303.895902.08640K562SRSF9
PSMB6ENSG00000142507.52102.129901644.973100.353703.659402.71580K562SYNCRIP
PSMB6ENSG00000142507.51235.73860993.899000.314102.264201.42190K562TRIM56
PSMB6ENSG00000142507.51448.673301694.58250-0.226202.468401.78830K562UPF1
PSMB6ENSG00000142507.51125.539001449.99750-0.365403.482702.50280K562WDR3
PSMB6ENSG00000142507.51990.270502652.80030-0.414602.504601.69160K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PSMB6 is not available on ENCORE database.





5 RBPs can affect the splicing of PSMB6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSPSMB6ENSG00000142507.5chr17+4701554470179047015744701790470130347014480.052000.000000.00000longerK562AQR
MXEPSMB6ENSG00000142507.5chr17+470002247000904700732470086446994384699591470097647011060.158000.000190.009401includedK562UCHL5
MXEPSMB6ENSG00000142507.5chr17+470002247000904700732470086446994384699591470097647011060.088000.001030.045341includedHepG2BCCIP
MXEPSMB6ENSG00000142507.5chr17+470002247000904700732470086446994384699591470097647011060.135000.000010.002121includedK562PHF6
MXEPSMB6ENSG00000142507.5chr17+470002247000904700732470086446994384699591470097647011060.087000.001330.045801includedHepG2SUPV3L1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PSMB6 is not avaliable on ENCORE database.