PPFIBP2

General Information

Gene Name       : PPFIBP2
Gene ID             : ENSG00000166387.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PPFIBP2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PPFIBP2ENSG00000166387.1243.9938.2941.14ENCSR000AEF
HepG2PPFIBP2ENSG00000166387.1217.4015.6216.51ENCSR985KAT
K562PPFIBP2ENSG00000166387.121.102.281.69ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PPFIBP2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PPFIBP2 RNA is bound by 7 proteins.  







eCLIP assay for PPFIBP2 is not avaliable on ENCORE database.





7 proteins are bound to PPFIBP2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1176315357631595+3'-UTR,CDS,intron-Distal3.239993.21309HepG2GRWD1
chr1176745537674665+3'-UTR,intron-Distal,intron-Proximal3.964513.80435HepG2LSM11
chr1176143697614459+5'-UTR,CDS,intron-Distal,intron-Proximal3.315995.39266HepG2GRWD1
chr1176507427650799+CDS,intron-Distal,intron-Proximal4.020836.34662HepG2PRPF8
chr1176506887650763+CDS,intron-Distal,intron-Proximal3.610917.10944HepG2PPIG
chr1176495217649580+CDS,intron-Distal,intron-Proximal3.727944.68902HepG2PPIG
chr1176610487661104+CDS,intron-Distal,intron-Proximal3.005163.99124HepG2PPIG
chr1176576757657738+intron-Distal3.535274.08528HepG2SUGP2
chr1176590527659158+intron-Distal3.5419010.35946HepG2SUGP2
chr1176613627661441+intron-Distal4.473986.90077HepG2PTBP1
chr1176586807658765+intron-Distal3.183809.13358HepG2SUGP2
chr1176607687660839+intron-Distal3.516544.08528HepG2SUGP2
chr1176614567661564+intron-Distal4.918307.55717HepG2PTBP1
chr1176585897658639+intron-Distal3.873546.25619HepG2SUGP2
chr1176257377625834+intron-Distal4.229058.18013HepG2HNRNPL
chr1176576267657675+intron-Distal3.384073.84025HepG2SUGP2
chr1176593927659455+intron-Distal3.369678.04518HepG2SUGP2
chr1176589937659010+intron-Distal4.233483.84389HepG2SUGP2
chr1176600797660112+intron-Distal4.173694.28663HepG2SUGP2
chr1176582457658295+intron-Distal3.662155.78794HepG2SUGP2
chr1176603267660368+intron-Distal3.457214.84410HepG2SUGP2
chr1176594557659519+intron-Distal3.921576.73852HepG2SUGP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PPFIBP2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PPFIBP2 is not available on ENCORE database.

  • 101 RBPs can affect the levels of PPFIBP2.  








The Knockdown/knockout RNA-Seq assay for PPFIBP2 is not available on ENCORE database.





101 RBPs can affect the gene expression of PPFIBP2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PPFIBP2ENSG00000166387.7609.980701079.93930-0.824108.997807.44840HepG2ABCF1
PPFIBP2ENSG00000166387.7203.75570766.61580-1.9117024.5747023.17140HepG2ACO1
PPFIBP2ENSG00000166387.7442.55390692.46180-0.645905.601004.25170HepG2ADAR
PPFIBP2ENSG00000166387.7427.519901526.28580-1.8360035.6269034.00060HepG2AKAP1
PPFIBP2ENSG00000166387.7671.163701344.75650-1.0026013.1233011.06860HepG2AKAP8
PPFIBP2ENSG00000166387.7481.54580770.06960-0.677305.935704.84950HepG2AKAP8L
PPFIBP2ENSG00000166387.7824.743601262.88600-0.614705.851704.73240HepG2ASCC1
PPFIBP2ENSG00000166387.7752.78690974.43030-0.372302.746301.34860HepG2ATP5C1
PPFIBP2ENSG00000166387.7753.03260461.382300.706605.635204.39960HepG2BCLAF1
PPFIBP2ENSG00000166387.7885.386701167.29630-0.398802.206901.34490HepG2CCAR1
PPFIBP2ENSG00000166387.7568.93080766.27120-0.429603.261502.55020HepG2CKAP4
PPFIBP2ENSG00000166387.7364.99330692.66080-0.924306.342805.18570HepG2CNOT7
PPFIBP2ENSG00000166387.7955.37780513.767500.8949011.234709.95250HepG2CPSF6
PPFIBP2ENSG00000166387.7160.66720327.97680-1.029508.072506.39310HepG2CSTF2
PPFIBP2ENSG00000166387.7380.91020964.14990-1.3398032.9237031.20730HepG2CELF1
PPFIBP2ENSG00000166387.71201.533001036.654200.212802.124701.46210HepG2DAZAP1
PPFIBP2ENSG00000166387.7457.08370708.92800-0.633205.730604.58920HepG2DDX19B
PPFIBP2ENSG00000166387.7946.98140649.168200.544605.088004.19710HepG2DDX21
PPFIBP2ENSG00000166387.71168.53180915.519100.351902.656701.38390HepG2DDX47
PPFIBP2ENSG00000166387.7562.445801255.90460-1.1589015.4037014.10590HepG2DDX6
PPFIBP2ENSG00000166387.7552.01410765.95120-0.472503.135102.15890HepG2EEF2
PPFIBP2ENSG00000166387.7465.13440638.54310-0.457102.951801.80880HepG2EFTUD2
PPFIBP2ENSG00000166387.7838.925601299.11270-0.630904.430703.57090HepG2EIF4B
PPFIBP2ENSG00000166387.7569.273901090.46310-0.9377010.081808.73540HepG2FIP1L1
PPFIBP2ENSG00000166387.7818.965401002.28390-0.291402.088401.39770HepG2FUBP3
PPFIBP2ENSG00000166387.7528.20140726.70120-0.460302.345501.31290HepG2FUS
PPFIBP2ENSG00000166387.7765.162001346.20440-0.815109.857308.62280HepG2FXR1
PPFIBP2ENSG00000166387.7812.905801248.85090-0.619405.580604.64900HepG2G3BP1
PPFIBP2ENSG00000166387.7923.398001325.75140-0.521804.633303.46970HepG2G3BP2
PPFIBP2ENSG00000166387.7405.77000553.62220-0.448202.615001.74700HepG2GEMIN5
PPFIBP2ENSG00000166387.71379.56890582.396701.2440019.3152017.78260HepG2GPKOW
PPFIBP2ENSG00000166387.7425.22910641.18060-0.592503.286302.06670HepG2GRSF1
PPFIBP2ENSG00000166387.7409.13330585.59920-0.517302.683701.34000HepG2HNRNPA0
PPFIBP2ENSG00000166387.7412.54710703.94740-0.770907.795706.79420HepG2HNRNPA1
PPFIBP2ENSG00000166387.7380.17610571.85800-0.589003.586101.98980HepG2HNRNPAB
PPFIBP2ENSG00000166387.7779.23750506.101500.622507.823606.69700HepG2HNRNPF
PPFIBP2ENSG00000166387.7911.468701264.46050-0.472304.118503.28010HepG2HNRNPK
PPFIBP2ENSG00000166387.7681.84840944.29940-0.469806.647005.64660HepG2HNRNPL
PPFIBP2ENSG00000166387.7736.33760555.791800.405702.517101.91240HepG2HNRNPLL
PPFIBP2ENSG00000166387.7567.00510777.84030-0.456105.216004.40420HepG2HNRNPU
PPFIBP2ENSG00000166387.71021.394001464.44130-0.519803.682002.26120HepG2HSPD1
PPFIBP2ENSG00000166387.7831.27620498.358800.738006.932205.83110HepG2IGF2BP1
PPFIBP2ENSG00000166387.7943.119001269.44700-0.428703.129202.41680HepG2IGF2BP2
PPFIBP2ENSG00000166387.7325.729501191.25120-1.8707012.3780010.44890HepG2IGF2BP3
PPFIBP2ENSG00000166387.7635.733201276.81420-1.0061010.870308.81540HepG2KHSRP
PPFIBP2ENSG00000166387.7751.010101232.84610-0.715106.090604.85120HepG2LARP4
PPFIBP2ENSG00000166387.7380.12220623.63770-0.714206.656304.93160HepG2LARP7
PPFIBP2ENSG00000166387.7605.620901354.22620-1.1610016.1118014.68470HepG2MATR3
PPFIBP2ENSG00000166387.7344.72810650.75940-0.916705.990604.49080HepG2METAP2
PPFIBP2ENSG00000166387.71009.12240566.832800.832006.136904.66270HepG2MTPAP
PPFIBP2ENSG00000166387.7779.927801386.13810-0.829709.634808.49310HepG2NCBP2
PPFIBP2ENSG00000166387.7375.30150563.89920-0.587404.498102.68850HepG2NIP7
PPFIBP2ENSG00000166387.7753.414001027.94650-0.448304.741003.74320HepG2NOL12
PPFIBP2ENSG00000166387.7676.23120492.814900.456402.962602.18920HepG2NSUN2
PPFIBP2ENSG00000166387.7214.93820633.05570-1.5584014.1057012.06410HepG2PABPC1
PPFIBP2ENSG00000166387.7531.01680769.92080-0.536004.255303.23190HepG2PARN
PPFIBP2ENSG00000166387.7763.571601319.01510-0.7886017.8440016.51820HepG2PCBP1
PPFIBP2ENSG00000166387.7346.57280621.13800-0.841805.428703.32480HepG2PNPT1
PPFIBP2ENSG00000166387.7685.26020828.42970-0.273702.152801.46270HepG2PRPF4
PPFIBP2ENSG00000166387.7467.89310723.25970-0.628302.827401.59840HepG2PRPF6
PPFIBP2ENSG00000166387.7924.172201342.13110-0.538309.099608.22320HepG2PTBP1
PPFIBP2ENSG00000166387.7566.320201041.68300-0.8792021.1249019.79610HepG2PUM1
PPFIBP2ENSG00000166387.7865.979901040.91330-0.265401.867301.31070HepG2PUM2
PPFIBP2ENSG00000166387.71023.11640780.821900.389803.969703.25660HepG2PUS1
PPFIBP2ENSG00000166387.71110.155201453.59550-0.388904.400003.63860HepG2QKI
PPFIBP2ENSG00000166387.7218.25560664.01680-1.6052013.1642011.73120HepG2RAVER1
PPFIBP2ENSG00000166387.7688.05050961.98180-0.483505.490604.82310HepG2RBM22
PPFIBP2ENSG00000166387.7741.143401319.21830-0.8319013.6620012.23150HepG2RBM25
PPFIBP2ENSG00000166387.7373.56650752.00200-1.0094011.616609.56080HepG2RBM27
PPFIBP2ENSG00000166387.7612.342501493.67640-1.2865041.4028039.86630HepG2NELFE
PPFIBP2ENSG00000166387.7742.908601391.13230-0.9050022.5227021.05830HepG2RECQL
PPFIBP2ENSG00000166387.7346.61610605.02330-0.803708.473907.46810HepG2RPS19
PPFIBP2ENSG00000166387.7539.94160707.95860-0.390902.437001.43170HepG2RPS5
PPFIBP2ENSG00000166387.7225.90270398.36770-0.818405.196504.15130HepG2RRP9
PPFIBP2ENSG00000166387.7342.07700607.23910-0.827907.583406.04950HepG2SERBP1
PPFIBP2ENSG00000166387.7524.307201063.61100-1.0205010.448609.07560HepG2SF3A3
PPFIBP2ENSG00000166387.7874.79810550.124800.669106.706605.64920HepG2SF3B1
PPFIBP2ENSG00000166387.7734.543101397.36060-0.9278023.4061021.96980HepG2SF3B4
PPFIBP2ENSG00000166387.7403.66810807.79600-1.0008021.8247020.28540HepG2SMN1
PPFIBP2ENSG00000166387.7625.225401086.50700-0.7972016.3368015.38600HepG2SRFBP1
PPFIBP2ENSG00000166387.7641.622301458.53020-1.1847037.6463036.34320HepG2SRSF1
PPFIBP2ENSG00000166387.7396.57660591.93420-0.577803.168002.08730HepG2SRSF3
PPFIBP2ENSG00000166387.7535.95630968.88500-0.854209.583008.51110HepG2SRSF5
PPFIBP2ENSG00000166387.7760.74310497.251000.613307.457806.40450HepG2SRSF7
PPFIBP2ENSG00000166387.7390.096501186.58180-1.6049057.8849056.02580HepG2SRSF9
PPFIBP2ENSG00000166387.71128.98180943.317100.259102.460101.97070HepG2SSB
PPFIBP2ENSG00000166387.7899.370001458.83570-0.697806.889405.00410HepG2SSRP1
PPFIBP2ENSG00000166387.7304.09850604.90490-0.992208.981006.90550HepG2STIP1
PPFIBP2ENSG00000166387.7807.126401101.87470-0.449106.320905.45130HepG2SUCLG1
PPFIBP2ENSG00000166387.7978.258301477.14970-0.594504.430302.73240HepG2SUGP2
PPFIBP2ENSG00000166387.7944.32570736.271000.358902.647901.72630HepG2SUPT6H
PPFIBP2ENSG00000166387.71015.435901310.95100-0.368504.084203.42360HepG2TAF15
PPFIBP2ENSG00000166387.7751.82000541.721700.472703.436902.63890HepG2TARDBP
PPFIBP2ENSG00000166387.7459.87530666.55970-0.535502.776301.30520HepG2TRA2A
PPFIBP2ENSG00000166387.7553.49710762.57520-0.462305.164804.44320HepG2TRIM56
PPFIBP2ENSG00000166387.7330.35310494.08540-0.580803.373301.63530HepG2TROVE2
PPFIBP2ENSG00000166387.7624.24200958.68910-0.619006.910205.43150HepG2TUFM
PPFIBP2ENSG00000166387.7178.83990307.00760-0.779604.896903.88040HepG2UCHL5
PPFIBP2ENSG00000166387.7680.34750910.68100-0.420704.833104.07780HepG2UTP3
PPFIBP2ENSG00000166387.7482.61000817.52710-0.7604011.5345010.32190HepG2ZC3H8
PPFIBP2ENSG00000166387.7769.841601037.40590-0.430306.374405.63350HepG2ZNF622
PPFIBP2ENSG00000166387.727.6454056.90840-1.041602.252301.75250K562PUS1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PPFIBP2 is not available on ENCORE database.





6 RBPs can affect the splicing of PPFIBP2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPPFIBP2ENSG00000166387.7chr11+7662263766231476609627661101766270976628510.123000.000470.02872includedHepG2PTBP1
SEPPFIBP2ENSG00000166387.7chr11+767207076721967670762767088576728867673075-0.132000.000130.00460excludedHepG2SRSF1
SEPPFIBP2ENSG00000166387.7chr11+764700776471227642165764225876495157649577-0.143000.002550.06320excludedHepG2SF3A3
SEPPFIBP2ENSG00000166387.7chr11+764700776471227642165764225876495157649577-0.134000.000320.01856excludedHepG2SF3B4
SEPPFIBP2ENSG00000166387.7chr11+764700776471227642165764225876495157649577-0.203000.000380.02043excludedHepG2HNRNPU
SEPPFIBP2ENSG00000166387.7chr11+764700776471227642165764225876495157649577-0.161000.001380.04961excludedHepG2HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PPFIBP2 is not avaliable on ENCORE database.