PLEKHA4

General Information

Gene Name       : PLEKHA4
Gene ID             : ENSG00000105559.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PLEKHA4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PLEKHA4ENSG00000105559.110.942.411.68ENCSR000AEF
HepG2PLEKHA4ENSG00000105559.118.052.605.33ENCSR985KAT
K562PLEKHA4ENSG00000105559.1113.317.6910.50ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PLEKHA4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PLEKHA4 RNA is bound by 6 proteins.  







eCLIP assay for PLEKHA4 is not avaliable on ENCORE database.





6 proteins are bound to PLEKHA4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr194935554749355637-3'-UTR,CDS,intron-Distal,intron-Proximal5.276727.41223K562SF3B4
chr194934038449340447-3'-UTR,intron-Distal,intron-Proximal3.473183.42164K562UPF1
chr194935707349357139-5'-UTR,CDS,intron-Distal,intron-Proximal3.648438.79534K562TIA1
chr194935613749356201-intron-Distal4.424883.41592K562XRCC6
chr194935637449356476-intron-Distal4.338004.92524K562TARDBP
chr194934856249348627-intron-Distal,intron-Proximal4.612276.77156K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PLEKHA4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PLEKHA4 is not available on ENCORE database.

  • 99 RBPs can affect the levels of PLEKHA4.  








The Knockdown/knockout RNA-Seq assay for PLEKHA4 is not available on ENCORE database.





99 RBPs can affect the gene expression of PLEKHA4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PLEKHA4ENSG00000105559.7343.15440227.562200.592504.528003.78690HepG2ACO1
PLEKHA4ENSG00000105559.7426.29430229.341400.894305.743305.00870HepG2AKAP1
PLEKHA4ENSG00000105559.7201.60070287.48700-0.512002.366001.80760HepG2BOP1
PLEKHA4ENSG00000105559.7357.57510236.580100.595803.451702.08370HepG2BUD13
PLEKHA4ENSG00000105559.7551.63970195.676601.4952028.1109026.51180HepG2CELF1
PLEKHA4ENSG00000105559.7105.96500179.27780-0.758603.337902.33030HepG2DDX24
PLEKHA4ENSG00000105559.7340.34920219.664800.631603.240402.57030HepG2DDX3X
PLEKHA4ENSG00000105559.7279.35420169.736900.718702.957302.16230HepG2DDX55
PLEKHA4ENSG00000105559.7467.27140188.759801.3076012.1452010.95890HepG2DDX6
PLEKHA4ENSG00000105559.7212.96810122.130000.802105.297704.44010HepG2DNAJC2
PLEKHA4ENSG00000105559.7266.78480181.396700.556402.386301.83400HepG2EIF2S1
PLEKHA4ENSG00000105559.7185.57440273.55770-0.559802.800801.70110HepG2ESF1
PLEKHA4ENSG00000105559.7300.83800202.321600.572202.692102.00970HepG2FXR1
PLEKHA4ENSG00000105559.7426.65200190.109901.1661010.760709.46510HepG2HNRNPK
PLEKHA4ENSG00000105559.7317.40090191.605300.728106.307405.32990HepG2HNRNPL
PLEKHA4ENSG00000105559.793.37720285.53090-1.6125013.1985011.96090HepG2HNRNPLL
PLEKHA4ENSG00000105559.7279.46110413.77090-0.566202.145601.42180HepG2LARP4
PLEKHA4ENSG00000105559.7388.05630203.510500.931106.166705.25390HepG2MATR3
PLEKHA4ENSG00000105559.7174.79990291.17960-0.736203.129302.09370HepG2MTPAP
PLEKHA4ENSG00000105559.7284.98670208.591400.450102.485301.76480HepG2NOL12
PLEKHA4ENSG00000105559.7374.78980155.900301.265405.667404.06790HepG2NONO
PLEKHA4ENSG00000105559.7297.39490103.714201.519709.864608.15030HepG2PABPC1
PLEKHA4ENSG00000105559.7196.87710136.045300.533102.343101.55660HepG2PARN
PLEKHA4ENSG00000105559.7508.76110186.156001.4504024.8811023.36870HepG2PCBP1
PLEKHA4ENSG00000105559.7136.02630216.28910-0.669103.724002.83850HepG2PRPF4
PLEKHA4ENSG00000105559.7408.93850189.424601.1102012.8891011.88160HepG2PTBP1
PLEKHA4ENSG00000105559.7131.96610205.14320-0.636502.797902.17010HepG2QKI
PLEKHA4ENSG00000105559.7443.38940274.094200.693805.772904.59220HepG2RBM15
PLEKHA4ENSG00000105559.7305.41510210.808200.534703.014502.45440HepG2NELFE
PLEKHA4ENSG00000105559.7315.89360196.345000.685904.733403.95610HepG2RECQL
PLEKHA4ENSG00000105559.7151.32830243.40080-0.685703.376102.63210HepG2RPLP0
PLEKHA4ENSG00000105559.7294.98640197.208400.580803.461202.80940HepG2SF3B4
PLEKHA4ENSG00000105559.7392.31240182.471001.104202.924101.42280HepG2SFPQ
PLEKHA4ENSG00000105559.7235.69900142.737000.723504.620503.82470HepG2SMN1
PLEKHA4ENSG00000105559.7283.27070162.073000.805404.362703.14180HepG2SMNDC1
PLEKHA4ENSG00000105559.7146.28330314.46830-1.104106.042004.88080HepG2SNRNP70
PLEKHA4ENSG00000105559.7415.85530333.506500.318301.928101.48710HepG2SRFBP1
PLEKHA4ENSG00000105559.7120.47650205.84580-0.772803.921003.38220HepG2SRSF1
PLEKHA4ENSG00000105559.7297.03960196.629900.595103.229902.56240HepG2SRSF5
PLEKHA4ENSG00000105559.7334.93140167.469000.9999010.401309.45010HepG2SRSF9
PLEKHA4ENSG00000105559.7222.53660289.56370-0.379801.881101.43700HepG2SSB
PLEKHA4ENSG00000105559.7154.9750099.181700.643802.339501.34180HepG2STIP1
PLEKHA4ENSG00000105559.7353.00480223.607700.658605.643004.81300HepG2SUCLG1
PLEKHA4ENSG00000105559.7190.36180113.240100.749302.890301.87290HepG2TFIP11
PLEKHA4ENSG00000105559.7256.26660134.750600.927307.216306.38020HepG2TRIM56
PLEKHA4ENSG00000105559.7353.25970205.960100.778303.767002.78310HepG2UBE2L3
PLEKHA4ENSG00000105559.7332.88810227.219400.550903.700802.50880HepG2UTP18
PLEKHA4ENSG00000105559.7179.24940272.49680-0.604303.026501.78530K562AARS
PLEKHA4ENSG00000105559.7732.44060335.209301.1275012.035509.60140K562ABCF1
PLEKHA4ENSG00000105559.7824.48830604.756500.447004.435303.74680K562AGGF1
PLEKHA4ENSG00000105559.7400.31040261.005500.616904.751802.94940K562BCCIP
PLEKHA4ENSG00000105559.7474.41100252.201600.9115010.787608.88440K562BCLAF1
PLEKHA4ENSG00000105559.7534.18070334.427200.675505.008903.82120K562BOP1
PLEKHA4ENSG00000105559.7363.13150233.504700.636903.620301.94700K562BUD13
PLEKHA4ENSG00000105559.7404.84550275.155100.557003.534902.07480K562CIRBP
PLEKHA4ENSG00000105559.7667.30580421.833200.661604.962102.96300K562CKAP4
PLEKHA4ENSG00000105559.7602.96060355.593000.761707.879806.54400K562CPSF6
PLEKHA4ENSG00000105559.7403.61510191.332501.0768010.791608.53400K562CSTF2
PLEKHA4ENSG00000105559.7725.62100473.498900.615807.351805.34980K562DDX21
PLEKHA4ENSG00000105559.7415.91630241.697600.783005.178102.88170K562DDX51
PLEKHA4ENSG00000105559.7342.37520223.642000.614303.239902.24680K562EFTUD2
PLEKHA4ENSG00000105559.7586.60060352.036000.736607.744605.58210K562EXOSC5
PLEKHA4ENSG00000105559.7402.05590240.983600.738405.613204.38090K562FIP1L1
PLEKHA4ENSG00000105559.7639.53370361.805600.821707.912006.42010K562FMR1
PLEKHA4ENSG00000105559.7573.36390306.662100.902708.467406.77160K562FTO
PLEKHA4ENSG00000105559.7176.54530456.58670-1.3709019.4989018.00740K562FXR1
PLEKHA4ENSG00000105559.7378.47590224.225800.755103.193201.64680K562GEMIN5
PLEKHA4ENSG00000105559.7656.53990339.504600.9514010.995309.38960K562GPKOW
PLEKHA4ENSG00000105559.7780.94800427.346900.869709.801308.35410K562GRSF1
PLEKHA4ENSG00000105559.7450.13070298.066900.594604.073203.36550K562HNRNPC
PLEKHA4ENSG00000105559.7307.62200198.225400.633903.244002.22910K562HNRNPM
PLEKHA4ENSG00000105559.7674.14960534.020900.336102.482201.63570K562HNRNPU
PLEKHA4ENSG00000105559.7456.13450326.704500.481402.814602.01270K562HSPD1
PLEKHA4ENSG00000105559.7466.03830256.912600.859106.206604.40850K562IGF2BP2
PLEKHA4ENSG00000105559.7482.32920289.892600.734404.392703.18870K562KRR1
PLEKHA4ENSG00000105559.7476.53000269.244700.823507.006605.44910K562MATR3
PLEKHA4ENSG00000105559.7539.80370331.394000.703806.016104.69740K562METAP2
PLEKHA4ENSG00000105559.7342.63880220.589300.635203.261301.82960K562NONO
PLEKHA4ENSG00000105559.7820.86460566.013800.536206.346005.27780K562NSUN2
PLEKHA4ENSG00000105559.7381.80560263.835700.533103.545302.00650K562PCBP1
PLEKHA4ENSG00000105559.7330.39140240.039400.460802.217501.34650K562PCBP2
PLEKHA4ENSG00000105559.7563.19130343.448900.713407.001105.73630K562POLR2G
PLEKHA4ENSG00000105559.7557.10900273.582701.025904.825303.69600K562PPIG
PLEKHA4ENSG00000105559.7416.81390267.260400.641104.119502.98550K562PSIP1
PLEKHA4ENSG00000105559.7380.60370262.161000.537703.659802.90750K562PTBP1
PLEKHA4ENSG00000105559.7467.22830739.66110-0.662703.566502.64260K562PUF60
PLEKHA4ENSG00000105559.7535.76010787.07300-0.554903.217502.06320K562PUM1
PLEKHA4ENSG00000105559.7217.37380140.055900.634103.141901.71980K562RBM25
PLEKHA4ENSG00000105559.7420.86650245.027500.780303.522401.89290K562RBM34
PLEKHA4ENSG00000105559.7390.77700243.899100.680005.005003.66850K562RCC2
PLEKHA4ENSG00000105559.7356.25490221.614600.684803.369602.46680K562RPS19
PLEKHA4ENSG00000105559.7652.76200322.878201.015505.645704.22490K562SF3B1
PLEKHA4ENSG00000105559.7232.37970153.538100.597803.162702.24710K562SF3B4
PLEKHA4ENSG00000105559.7355.04240231.203700.618703.689002.45800K562SRFBP1
PLEKHA4ENSG00000105559.7404.07700217.410000.894106.894304.18550K562SRP68
PLEKHA4ENSG00000105559.7401.59540280.123100.519602.972401.87170K562SRSF4
PLEKHA4ENSG00000105559.7447.01420242.793000.880508.032406.14330K562SRSF5
PLEKHA4ENSG00000105559.7461.87210316.166700.546703.456401.90940K562SSRP1
PLEKHA4ENSG00000105559.7445.71650289.163200.624103.945402.40560K562STAU1
PLEKHA4ENSG00000105559.7159.55260344.51400-1.110508.601107.15030K562SYNCRIP
PLEKHA4ENSG00000105559.7584.26800260.082301.1676014.4111012.54670K562TARDBP
PLEKHA4ENSG00000105559.7324.17920192.043000.755303.530601.63430K562TFIP11
PLEKHA4ENSG00000105559.7446.01650250.890500.829907.710006.23940K562TIA1
PLEKHA4ENSG00000105559.7470.29980257.052700.871406.965905.42600K562TIAL1
PLEKHA4ENSG00000105559.7458.79470246.304100.897303.908102.57760K562TRA2A
PLEKHA4ENSG00000105559.7489.76430273.150600.842307.585805.83830K562TRIM56
PLEKHA4ENSG00000105559.7499.41520281.830800.825307.075404.72890K562TRIP6
PLEKHA4ENSG00000105559.7374.29350222.947700.747404.624403.27450K562UCHL5
PLEKHA4ENSG00000105559.7288.09130534.08600-0.890506.127104.91940K562WDR43
PLEKHA4ENSG00000105559.7443.16170227.119000.964306.426604.33190K562XRN2
PLEKHA4ENSG00000105559.71009.43300693.621600.541203.494702.50570K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PLEKHA4 is not available on ENCORE database.





13 RBPs can affect the splicing of PLEKHA4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPLEKHA4ENSG00000105559.7chr19-493424614934252049341273493413864934440549344567-0.348000.002220.06709excludedK562PRPF8
SEPLEKHA4ENSG00000105559.7chr19-493424614934252049341273493413864934440549344567-0.350000.002720.04667excludedHepG2U2AF1
SEPLEKHA4ENSG00000105559.7chr19-493424614934252049341273493413864934440549344567-0.486000.005430.05664excludedHepG2U2AF2
SEPLEKHA4ENSG00000105559.7chr19-493424614934252049341273493413864934440549344567-0.333000.000720.05594excludedK562SUPV3L1
SEPLEKHA4ENSG00000105559.7chr19-493424614934252049341273493413864934440549344567-0.286000.002040.08542excludedK562EFTUD2
SEPLEKHA4ENSG00000105559.7chr19-493606784936075349357473493575214936211649362396-0.518000.002570.05336excludedHepG2SRSF1
SEPLEKHA4ENSG00000105559.7chr19-493477594934791049344405493445674934862649348703-0.083000.000000.00015excludedK562HNRNPC
MXEPLEKHA4ENSG00000105559.7chr19-49362116493623964936245849362596493606784936075349362725493629410.179000.000020.003791includedK562HNRNPL
MXEPLEKHA4ENSG00000105559.7chr19-49342461493425204934440549344567493412734934138649348626493487030.270000.002190.058701includedK562EFTUD2
MXEPLEKHA4ENSG00000105559.7chr19-4934246149342520493444054934456749341273493413864934862649348703-0.212000.000500.032882includedK562PHF6
MXEPLEKHA4ENSG00000105559.7chr19-49357473493575214936211649362396493572634935734449362725493629410.200000.000070.005551includedK562SBDS
MXEPLEKHA4ENSG00000105559.7chr19-4936211649362396493624584936259649360678493607534936272549362941-0.229000.002220.084822includedK562IGF2BP2
MXEPLEKHA4ENSG00000105559.7chr19-4936211649362396493624584936259649360678493607534936272549362941-0.269000.001680.076602includedK562HNRNPK
MXEPLEKHA4ENSG00000105559.7chr19-4936211649362396493624584936259649360678493607534936272549362941-0.071000.004830.061852includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PLEKHA4 is not avaliable on ENCORE database.