PARP2

General Information

Gene Name       : PARP2
Gene ID             : ENSG00000129484.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PARP2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PARP2ENSG00000129484.1345.8041.4143.60ENCSR000AEF
HepG2PARP2ENSG00000129484.1352.7367.6160.17ENCSR985KAT
K562PARP2ENSG00000129484.1327.3930.8229.11ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PARP2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PARP2 RNA is bound by 15 proteins.  







eCLIP assay for PARP2 is not avaliable on ENCORE database.





15 proteins are bound to PARP2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr142082587320825924+3'-UTR,CDS5.947835.06516K562PUM2
chr142082575320825839+3'-UTR,CDS,intron-Proximal3.071577.94218K562BUD13
chr142082227820822382+3'-UTR,CDS3.321407.32216K562UCHL5
chr142082578220825796+3'-UTR,intron-Proximal5.056926.77181K562U2AF2
chr142082310320823121+3'-UTR,CDS,intron-Proximal4.049854.00320K562AQR
chr142082307720823138+3'-UTR,CDS,intron-Proximal5.440994.68690HepG2PRPF8
chr142082596220826013+3'-UTR3.093113.69127HepG2BCLAF1
chr142082296920822999+3'-UTR,CDS,intron-Proximal4.754074.37348HepG2BCLAF1
chr142082595020825978+3'-UTR,CDS3.255563.31745K562ZNF622
chr142082579620825836+3'-UTR,CDS,intron-Proximal4.231946.67262K562U2AF2
chr142082581120825832+3'-UTR,CDS3.162936.51847HepG2U2AF2
chr142082044020820505+3'-UTR,CDS4.6209410.22656K562ZNF622
chr142082577620825855+3'-UTR,CDS,intron-Proximal3.260886.52802K562ZNF622
chr142082578220825811+3'-UTR,CDS,intron-Proximal3.140037.11994HepG2U2AF2
chr142082043520820507+3'-UTR,CDS,intron-Proximal3.622016.94506K562DDX24
chr142082227920822321+3'-UTR,CDS3.437703.59112HepG2PPIG
chr142082578320825835+3'-UTR,CDS,intron-Proximal4.703227.08280K562SF3B4
chr142082227820822345+3'-UTR,CDS4.065389.03438K562ZNF622
chr142082234520822406+3'-UTR,CDS3.675737.90527K562ZNF622
chr142082574120825783+3'-UTR,intron-Proximal3.496534.50936K562SF3B4
chr142082577520825826+3'-UTR,CDS,intron-Proximal3.296116.27771K562SMNDC1
chr142082238220822406+3'-UTR,CDS3.852105.30520K562UCHL5
chr142081868420818708+CDS,intron-Distal,intron-Proximal3.179133.84771K562ZNF622
chr142081920420819254+CDS,intron-Distal,intron-Proximal3.085335.08512HepG2BCLAF1
chr142082391620823971+CDS3.491515.26861K562DDX24
chr142081871620818781+CDS,intron-Distal3.718609.25963HepG2GRWD1
chr142081355320813572+CDS3.314884.33023K562ZNF622
chr142081920520819261+CDS,intron-Distal,intron-Proximal4.5910115.15328K562ZNF622
chr142081872220818781+CDS,intron-Distal3.603325.35431HepG2BCLAF1
chr142082474720824832+CDS,intron-Proximal3.049135.08732HepG2PPIG
chr142081923320819275+CDS,intron-Distal3.051115.41277K562UCHL5
chr142082475020824785+CDS3.687844.51739HepG2BCLAF1
chr142081872220818770+CDS,intron-Distal3.6456410.31263K562ZNF622
chr142082475320824843+CDS3.957768.00190HepG2GRWD1
chr142082391820823949+CDS4.683584.72838K562UCHL5
chr142081920520819253+CDS,intron-Distal,intron-Proximal3.263924.99980K562XRCC6
chr142081873620818782+CDS,intron-Distal,intron-Proximal3.936607.89918K562DDX24
chr142081920520819233+CDS,intron-Distal,intron-Proximal3.670817.79255K562UCHL5
chr142081356620813619+CDS4.193513.25089HepG2AQR
chr142082475020824801+CDS3.725917.25346K562UCHL5
chr142081503520815072+CDS3.639895.65306K562ZNF622
chr142081872420818781+CDS,intron-Distal3.617366.43326K562UCHL5
chr142081319320813281+CDS,intron-Proximal4.0637110.53109K562DDX24
chr142081920520819276+CDS,intron-Distal,intron-Proximal3.7471011.82429HepG2PPIG
chr142082455720824588+CDS3.526883.87469HepG2BCLAF1
chr142082554420825587+CDS,intron-Distal,intron-Proximal3.367623.16095HepG2U2AF2
chr142081920420819274+CDS,intron-Distal,intron-Proximal4.0609013.78659K562DDX24
chr142081324220813282+CDS,intron-Proximal3.240684.56061K562BUD13
chr142082524620825307+CDS3.096698.82455K562ZNF622
chr142082415020824182+CDS3.867413.34184HepG2GRWD1
chr142081321020813281+CDS,intron-Proximal4.074279.42122K562ZNF622
chr142082296920822982+CDS,intron-Proximal3.755784.49347K562UCHL5
chr142081312920813179+CDS3.327426.97987K562ZNF622
chr142081356920813619+CDS3.241283.39306HepG2GRWD1
chr142081877020818781+CDS,intron-Distal3.810658.04012K562ZNF622
chr142081312720813268+CDS,intron-Proximal3.971747.31178K562ZNF800
chr142082523120825303+CDS3.045686.91015HepG2GRWD1
chr142081920520819245+CDS,intron-Distal,intron-Proximal5.003067.71151HepG2GRWD1
chr142082533720825415+intron-Distal,intron-Proximal3.687126.21987K562AQR
chr142082312120823167+intron-Proximal5.492117.28294K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PARP2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PARP2 is not available on ENCORE database.

  • 101 RBPs can affect the levels of PARP2.  








The Knockdown/knockout RNA-Seq assay for PARP2 is not available on ENCORE database.





101 RBPs can affect the gene expression of PARP2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PARP2ENSG00000129484.9656.935801021.81100-0.637306.403704.96470HepG2ADAR
PARP2ENSG00000129484.9910.952401134.30970-0.316403.347502.51390HepG2AKAP8L
PARP2ENSG00000129484.9601.42080979.18560-0.703206.084304.94110HepG2ASCC1
PARP2ENSG00000129484.9626.26790956.42090-0.610904.477903.35750HepG2BCLAF1
PARP2ENSG00000129484.9999.105301551.90810-0.635307.839306.89580HepG2BOP1
PARP2ENSG00000129484.91155.002001436.26670-0.314402.835602.05490HepG2CALR
PARP2ENSG00000129484.9892.383801128.74650-0.339004.326503.53010HepG2CKAP4
PARP2ENSG00000129484.9898.457601147.53430-0.353003.063901.90420HepG2CPSF7
PARP2ENSG00000129484.91343.169101589.79740-0.243202.232501.64440HepG2CELF1
PARP2ENSG00000129484.9730.783601000.17560-0.452704.354703.19960HepG2DDX24
PARP2ENSG00000129484.9773.882101133.56990-0.550704.642003.84760HepG2DDX3X
PARP2ENSG00000129484.9820.875401082.07300-0.398601.995601.32760HepG2DDX55
PARP2ENSG00000129484.9950.667001247.19210-0.391703.067202.00980HepG2DDX5
PARP2ENSG00000129484.9816.358401028.92240-0.333903.190802.44010HepG2DNAJC21
PARP2ENSG00000129484.9818.172001019.81800-0.317803.769603.03050HepG2DNAJC2
PARP2ENSG00000129484.9611.22630881.02510-0.527503.661902.63070HepG2EIF3D
PARP2ENSG00000129484.9683.767401007.36330-0.559003.464702.69830HepG2EIF4B
PARP2ENSG00000129484.91137.608701615.48130-0.506005.048303.96830HepG2EIF4G2
PARP2ENSG00000129484.9919.318901427.15250-0.634502.349301.41990HepG2FTO
PARP2ENSG00000129484.9759.74700968.27920-0.349902.056501.47950HepG2G3BP1
PARP2ENSG00000129484.91052.018301615.14200-0.618505.864204.95610HepG2GPKOW
PARP2ENSG00000129484.91144.528601570.96030-0.456906.768705.41730HepG2HNRNPA2B1
PARP2ENSG00000129484.9849.411801155.44400-0.443903.879603.06930HepG2HNRNPC
PARP2ENSG00000129484.9995.267401402.15630-0.494507.862306.73260HepG2HNRNPF
PARP2ENSG00000129484.9959.062601380.72780-0.525706.608905.53200HepG2IGF2BP1
PARP2ENSG00000129484.9673.70000984.14780-0.546804.510103.66600HepG2IGF2BP2
PARP2ENSG00000129484.91005.136701172.44630-0.222102.408001.71830HepG2ILF2
PARP2ENSG00000129484.9822.998101032.06290-0.326603.925602.71520HepG2KIF1C
PARP2ENSG00000129484.91187.989601717.02780-0.531403.956302.96000HepG2LARP4
PARP2ENSG00000129484.91334.694001694.95680-0.344703.673302.79250HepG2NOL12
PARP2ENSG00000129484.91104.505401366.65740-0.307302.069501.41820HepG2NSUN2
PARP2ENSG00000129484.9720.64520956.96730-0.409202.705201.99040HepG2PABPC4
PARP2ENSG00000129484.9900.763401136.13860-0.334903.646702.68780HepG2PARN
PARP2ENSG00000129484.9823.96380965.15710-0.228201.830401.31960HepG2PCBP1
PARP2ENSG00000129484.9742.685001023.75180-0.463005.508004.49860HepG2PPIL4
PARP2ENSG00000129484.91753.411201155.229100.601903.946502.50320HepG2PRPF6
PARP2ENSG00000129484.9889.736301618.01500-0.8628014.8521013.61780HepG2PUF60
PARP2ENSG00000129484.91168.189601717.63000-0.5561013.4169012.31740HepG2PUM1
PARP2ENSG00000129484.91144.878501716.35320-0.584208.755007.59390HepG2PUM2
PARP2ENSG00000129484.9979.347701150.01950-0.231802.188101.62510HepG2PUS1
PARP2ENSG00000129484.9758.826701216.56040-0.681006.659705.11500HepG2RBM27
PARP2ENSG00000129484.91292.867801092.964800.242202.119701.63360HepG2NELFE
PARP2ENSG00000129484.91170.959001510.40350-0.367203.167802.44420HepG2RPLP0
PARP2ENSG00000129484.9688.947001041.57590-0.596303.609102.53100HepG2RPS10
PARP2ENSG00000129484.9544.30420857.24360-0.655307.133406.19950HepG2RPS19
PARP2ENSG00000129484.9876.257101122.05220-0.356702.142001.43270HepG2RPS2
PARP2ENSG00000129484.9571.10070944.05400-0.725104.863603.80140HepG2RPS3A
PARP2ENSG00000129484.9631.28320860.42910-0.446803.012102.02880HepG2SERBP1
PARP2ENSG00000129484.9905.290101525.67360-0.7530010.241408.96180HepG2SF3B1
PARP2ENSG00000129484.9802.540601022.47510-0.349403.518802.86310HepG2SF3B4
PARP2ENSG00000129484.91156.326001551.49720-0.424107.272906.21990HepG2SLBP
PARP2ENSG00000129484.9951.059701192.03510-0.325804.370103.59440HepG2SMN1
PARP2ENSG00000129484.9692.022801697.56580-1.2946014.6034012.82810HepG2SNRNP70
PARP2ENSG00000129484.92022.061601067.243100.9218029.4414028.26080HepG2SRSF1
PARP2ENSG00000129484.92196.490301641.522700.420102.849101.83130HepG2SRSF3
PARP2ENSG00000129484.91127.386901597.59680-0.502908.588207.56330HepG2SRSF5
PARP2ENSG00000129484.9997.644501377.55780-0.465506.995205.96920HepG2SRSF7
PARP2ENSG00000129484.9706.84240868.25960-0.296702.703102.15650HepG2SRSF9
PARP2ENSG00000129484.91756.743601334.709400.396306.570305.84330HepG2SSB
PARP2ENSG00000129484.9568.82110950.07120-0.7401010.314308.60650HepG2SUPT6H
PARP2ENSG00000129484.9642.621001077.25770-0.745306.189905.23760HepG2SUPV3L1
PARP2ENSG00000129484.91667.32930959.281200.7974017.6223016.38210HepG2TAF15
PARP2ENSG00000129484.9853.037201502.16930-0.8164011.6130010.28290HepG2TARDBP
PARP2ENSG00000129484.9446.18910722.09110-0.694505.296603.98180HepG2TFIP11
PARP2ENSG00000129484.9650.447001115.33070-0.7780012.4742011.54470HepG2TIAL1
PARP2ENSG00000129484.9655.860501125.27590-0.7788016.4883015.26490HepG2TRIM56
PARP2ENSG00000129484.91061.915901580.79030-0.574007.469905.92050HepG2TUFM
PARP2ENSG00000129484.9870.711601203.75900-0.467304.344303.56610HepG2U2AF1
PARP2ENSG00000129484.91309.866601673.27980-0.353302.113501.38800HepG2UBE2L3
PARP2ENSG00000129484.9841.662501125.77170-0.419605.776704.82610HepG2UPF1
PARP2ENSG00000129484.9909.635701157.15490-0.347203.725102.52810HepG2UTP18
PARP2ENSG00000129484.91507.543901086.892200.471907.636006.72210HepG2UTP3
PARP2ENSG00000129484.91415.66790969.228500.5465011.013009.82330HepG2ZC3H8
PARP2ENSG00000129484.9925.566601238.13690-0.419806.894906.13250HepG2ZNF622
PARP2ENSG00000129484.93400.466901899.020700.8404032.7801030.91230K562AGGF1
PARP2ENSG00000129484.92639.287701976.049400.417404.846203.97280K562AKAP8L
PARP2ENSG00000129484.91419.260901746.17450-0.299102.602201.40080K562APOBEC3C
PARP2ENSG00000129484.92178.683301493.563300.544606.533405.69420K562AQR
PARP2ENSG00000129484.92555.042902073.412600.301203.086302.11880K562ATP5C1
PARP2ENSG00000129484.91252.927401519.80630-0.278602.745601.64470K562CPEB4
PARP2ENSG00000129484.91197.558001572.46730-0.392905.666604.78460K562DDX47
PARP2ENSG00000129484.92934.596102126.168200.464809.177807.38880K562DKC1
PARP2ENSG00000129484.9676.86660984.01230-0.539806.996205.92910K562EIF2S2
PARP2ENSG00000129484.9572.26530797.54000-0.478902.896801.83610K562EIF3D
PARP2ENSG00000129484.91508.496801978.97720-0.391605.651204.33130K562EIF4G2
PARP2ENSG00000129484.91179.26180930.882100.341103.362601.37580K562FUBP3
PARP2ENSG00000129484.9771.308801026.15270-0.411904.444303.70160K562FXR1
PARP2ENSG00000129484.91423.415601053.265700.434404.354402.52390K562G3BP1
PARP2ENSG00000129484.91605.400301170.561500.455602.937702.20650K562G3BP2
PARP2ENSG00000129484.9918.344801132.96980-0.303002.150001.44700K562GPKOW
PARP2ENSG00000129484.93035.297901802.300200.751903.823802.31270K562HNRNPA2B1
PARP2ENSG00000129484.9764.721201044.39230-0.449704.088803.37860K562HNRNPC
PARP2ENSG00000129484.91168.51260891.014400.391102.483301.60350K562HNRNPM
PARP2ENSG00000129484.93012.830302096.969100.522707.835906.27270K562KIF1C
PARP2ENSG00000129484.92794.727002007.407300.477302.914301.80390K562MAK16
PARP2ENSG00000129484.9936.310101155.47530-0.303402.367001.51960K562MATR3
PARP2ENSG00000129484.92716.980001646.594600.722405.263503.91060K562NAA15
PARP2ENSG00000129484.91465.709501259.253000.218902.567601.84490K562NSUN2
PARP2ENSG00000129484.92620.172401576.473900.732903.683802.49640K562PABPN1
PARP2ENSG00000129484.91418.044201131.745100.325302.947601.55360K562PCBP1
PARP2ENSG00000129484.9679.00770875.79500-0.367203.152302.29350K562POLR2G
PARP2ENSG00000129484.9943.98420724.815400.381002.608501.87960K562PRPF8
PARP2ENSG00000129484.9786.148001124.88980-0.516905.946005.00510K562PTBP1
PARP2ENSG00000129484.91807.512602250.22970-0.316104.150602.96680K562PUM2
PARP2ENSG00000129484.94464.755501959.468001.1880030.1141028.30030K562PUS1
PARP2ENSG00000129484.93133.102501909.397700.7144012.7563011.48330K562RBM15
PARP2ENSG00000129484.91574.014401243.457100.340003.107901.39840K562RBM17
PARP2ENSG00000129484.91389.596401110.328400.323602.617801.33190K562RBM25
PARP2ENSG00000129484.9797.456301051.46790-0.398902.897201.47650K562RBM34
PARP2ENSG00000129484.9654.908401135.10860-0.793509.837907.71640K562NELFE
PARP2ENSG00000129484.9863.307801451.53950-0.749608.735606.84660K562RPS3
PARP2ENSG00000129484.92986.696401655.740400.851004.369002.71660K562SNRNP200
PARP2ENSG00000129484.91024.571401401.32010-0.451804.653403.22330K562SRSF4
PARP2ENSG00000129484.91407.401901132.731900.313103.201301.93860K562SRSF7
PARP2ENSG00000129484.91026.26670806.513300.347502.919801.59940K562SSB
PARP2ENSG00000129484.9730.423201116.07730-0.611606.276705.17150K562TARDBP
PARP2ENSG00000129484.9891.795501076.58010-0.271702.009701.31900K562TIA1
PARP2ENSG00000129484.93057.002501986.929800.621502.512401.30200K562UTP18
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PARP2 is not available on ENCORE database.





15 RBPs can affect the splicing of PARP2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPARP2ENSG00000129484.9chr14+208255542082567920825209208253082082579620826063-0.184000.000000.00083excludedHepG2G3BP1
SEPARP2ENSG00000129484.9chr14+2082555420825679208252092082530820825796208260630.093000.004100.06471includedK562SRSF1
SEPARP2ENSG00000129484.9chr14+208192052081928120818547208187812082040320820506-0.090000.000030.00099excludedK562SF3B4
SEPARP2ENSG00000129484.9chr14+208255542082567920825209208253082082579620826063-0.214000.000010.01643excludedK562TROVE2
SEPARP2ENSG00000129484.9chr14+208255542082567920825209208253082082579620826063-0.109000.000780.02190excludedHepG2HNRNPK
SEPARP2ENSG00000129484.9chr14+208255542082567920825176208253082082579620826064-0.241000.000000.00000excludedK562AQR
SEPARP2ENSG00000129484.9chr14+208238512082397420822993208231062082405520824190-0.055000.006430.05722excludedK562AQR
SEPARP2ENSG00000129484.9chr14+208192052081928120818684208187812082040320820506-0.117000.000000.00000excludedK562AQR
SEPARP2ENSG00000129484.9chr14+208255542082567920825209208253082082579620826063-0.214000.000000.00000excludedK562PUS1
SEPARP2ENSG00000129484.9chr14+208255542082567920825209208253082082579620826063-0.143000.000100.01000excludedHepG2NCBP2
SEPARP2ENSG00000129484.9chr14+208192052081928120818684208187812082040320820506-0.094000.000010.00065excludedHepG2SF3A3
SEPARP2ENSG00000129484.9chr14+208255542082567920825209208253082082579620826063-0.175000.000000.00023excludedK562HNRNPUL1
SEPARP2ENSG00000129484.9chr14+208255542082567920825209208253082082579620826063-0.117000.003630.08801excludedK562UTP18
SEPARP2ENSG00000129484.9chr14+208255542082567920825209208253082082579620826063-0.139000.000400.04739excludedHepG2TAF15
SEPARP2ENSG00000129484.9chr14+208255542082567920825209208253082082579620826063-0.279000.000000.00004excludedK562U2AF2
SEPARP2ENSG00000129484.9chr14+208255542082567920825209208253082082579620826063-0.140000.000010.00070excludedK562RBM15
A3SSPARP2ENSG00000129484.9chr14+2082037820820506208204032082050620819205208192810.087000.000000.00000longerK562AQR
A3SSPARP2ENSG00000129484.9chr14+2081352820813745208135522081374520813090208132850.155000.000000.00000longerK562AQR
A5SSPARP2ENSG00000129484.9chr14+2081309020813285208130902081324620813552208136230.190000.000040.02019longerHepG2DDX59
A5SSPARP2ENSG00000129484.9chr14+2081309020813285208130902081324620813552208136230.156000.002660.07992longerHepG2U2AF2
MXEPARP2ENSG00000129484.9chr14+20813528208136232081502120815072208130902081328520818684208187810.182000.000000.000001includedK562AQR
MXEPARP2ENSG00000129484.9chr14+20813531208136232081502120815072208130902081328520818684208187810.119000.000000.000001includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PARP2 is not avaliable on ENCORE database.