NR1H2

General Information

Gene Name       : NR1H2
Gene ID             : ENSG00000131408.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NR1H2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NR1H2ENSG00000131408.131.1411.016.08ENCSR000AEF
HepG2NR1H2ENSG00000131408.1310.912.296.60ENCSR985KAT
K562NR1H2ENSG00000131408.1336.8316.0226.42ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NR1H2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • NR1H2 RNA is bound by 21 proteins.  







eCLIP assay for NR1H2 is not avaliable on ENCORE database.





21 proteins are bound to NR1H2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr195088610050886180+3'-UTR4.100983.34382K562APOBEC3C
chr195087975250879882+3'-UTR,5'-UTR,intron-Distal,intron-Proximal4.1844916.46444K562RBFOX2
chr195088613550886145+3'-UTR5.8247622.89009K562PABPC4
chr195088303550883079+3'-UTR,CDS,intron-Proximal3.100293.86052K562YBX3
chr195088516550885238+3'-UTR,CDS,intron-Proximal3.700717.67169K562SF3B4
chr195087978050879834+3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.482613.06830K562UPF1
chr195088243650882484+3'-UTR,CDS,intron-Proximal4.181375.47926K562AQR
chr195088612850886135+3'-UTR4.790447.71026K562PABPC4
chr195088614550886175+3'-UTR6.0781556.99362K562PABPC4
chr195088611950886176+3'-UTR4.574266.86847K562CPEB4
chr195087992950880013+3'-UTR,5'-UTR,intron-Proximal3.393064.79829K562EFTUD2
chr195087977750879857+3'-UTR,5'-UTR,intron-Distal,intron-Proximal4.372824.04372HepG2BCLAF1
chr195088171750881786+3'-UTR,CDS,intron-Proximal3.673494.13013K562SF3B4
chr195088604650886121+3'-UTR5.346824.55547K562PCBP1
chr195088610450886128+3'-UTR3.765563.18912K562PABPC4
chr195088136750881447+3'-UTR,CDS,intron-Distal,intron-Proximal5.347438.34848K562PRPF8
chr195087997550880042+3'-UTR,5'-UTR,intron-Proximal4.450684.46422K562UPF1
chr195088184050881900+3'-UTR,CDS3.474704.22917HepG2PPIG
chr195088175950881842+3'-UTR,CDS,intron-Proximal3.398387.52067K562EFTUD2
chr195088144450881497+3'-UTR,CDS,intron-Distal3.436843.61259K562ZNF622
chr195088067450880831+3'-UTR,5'-UTR,intron-Distal,intron-Proximal8.0856054.01412K562RBFOX2
chr195088203350882091+3'-UTR,CDS,intron-Proximal4.969284.68690HepG2PRPF8
chr195088611750886175+3'-UTR4.115454.86325K562DDX6
chr195088112650881175+3'-UTR,CDS,intron-Proximal5.268387.81430K562AQR
chr195087977450879839+3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.605183.01994K562BUD13
chr195087995150879996+3'-UTR,5'-UTR,intron-Proximal3.502464.25142K562BUD13
chr195088048450880553+5'-UTR,intron-Distal3.389754.07440K562PRPF8
chr195088048150880555+5'-UTR,intron-Distal4.991085.25173HepG2RBFOX2
chr195088068550880788+5'-UTR,intron-Distal,intron-Proximal4.076383.85148K562GTF2F1
chr195088058450880637+5'-UTR,intron-Distal,intron-Proximal4.473336.70492K562RBFOX2
chr195088068750880781+5'-UTR,intron-Distal,intron-Proximal6.0871612.02968K562DDX6
chr195088067650880748+5'-UTR,intron-Distal,intron-Proximal5.8806914.55922HepG2RBFOX2
chr195088045050880529+5'-UTR,intron-Distal4.391384.01425K562AKAP8L
chr195088044750880557+5'-UTR,intron-Distal6.0922125.64388K562DROSHA
chr195087990950879975+5'-UTR,intron-Proximal4.8597015.49920K562RBFOX2
chr195088040450880565+5'-UTR,intron-Distal7.5599035.22614K562RBFOX2
chr195088069850880741+5'-UTR,intron-Distal,intron-Proximal4.2953815.48166K562DROSHA
chr195088163750881700+CDS,intron-Distal,intron-Proximal3.837923.53569K562LIN28B
chr195088169150881771+CDS,intron-Proximal4.001215.55508K562BUD13
chr195088028350880430+intron-Distal8.5395252.76275K562DROSHA
chr195088019450880245+intron-Distal7.0076718.63236K562DROSHA
chr195088060350880643+intron-Distal,intron-Proximal4.449055.52571HepG2RBFOX2
chr195088029650880404+intron-Distal6.5093919.22773K562RBFOX2
chr195088017050880243+intron-Distal,intron-Proximal5.6913311.39317HepG2RBFOX2
chr195088028350880395+intron-Distal6.3492822.29640HepG2RBFOX2
chr195083494750835034+intron-Distal3.412613.00914HepG2PTBP1
chr195083491150835050+intron-Distal5.786388.42544K562PTBP1
chr195088019950880245+intron-Distal4.552666.26242K562RBFOX2
chr195088010650880157+intron-Proximal4.114404.77785K562RBFOX2
chr195088314350883209+intron-Proximal3.312703.01994K562BUD13
chr195088314450883191+intron-Proximal3.967667.30031K562AQR
chr195088009250880161+intron-Proximal4.9680314.94072HepG2RBFOX2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NR1H2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NR1H2 is not available on ENCORE database.

  • 111 RBPs can affect the levels of NR1H2.  








The Knockdown/knockout RNA-Seq assay for NR1H2 is not available on ENCORE database.





111 RBPs can affect the gene expression of NR1H2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NR1H2ENSG00000131408.9723.03040349.679101.047908.857607.96550HepG2AKAP1
NR1H2ENSG00000131408.9383.19790287.133300.416302.674001.91870HepG2AKAP8L
NR1H2ENSG00000131408.9461.98670289.290200.675202.772401.98760HepG2ASCC1
NR1H2ENSG00000131408.9409.75990286.481800.516202.704601.31580HepG2ATP5C1
NR1H2ENSG00000131408.9202.22230373.99100-0.887107.049206.03390HepG2AUH
NR1H2ENSG00000131408.9430.43190162.768001.4029015.7152014.45590HepG2BOP1
NR1H2ENSG00000131408.9461.34490274.858500.747104.028803.10490HepG2CIRBP
NR1H2ENSG00000131408.9446.17660285.722500.642906.461905.52280HepG2CKAP4
NR1H2ENSG00000131408.9425.49710132.129801.6871014.0921012.41690HepG2CNOT7
NR1H2ENSG00000131408.9215.56460149.420000.528602.001701.40600HepG2CPSF6
NR1H2ENSG00000131408.9444.29380261.476400.764705.809004.24750HepG2CPSF7
NR1H2ENSG00000131408.9355.14590176.832501.0059010.999709.67640HepG2DAZAP1
NR1H2ENSG00000131408.9157.1362081.713300.943304.437102.98850HepG2DDX1
NR1H2ENSG00000131408.9629.95370334.880400.911504.285403.52150HepG2DDX3X
NR1H2ENSG00000131408.9274.34410149.347500.877203.497302.64040HepG2DDX55
NR1H2ENSG00000131408.9748.68680287.871001.378803.496502.80910HepG2DDX6
NR1H2ENSG00000131408.9226.6547080.122801.5001013.1567011.71410HepG2DNAJC21
NR1H2ENSG00000131408.9222.6534079.423701.4871014.3849013.01240HepG2DNAJC2
NR1H2ENSG00000131408.9601.48670276.537101.121006.194705.32610HepG2EIF2S1
NR1H2ENSG00000131408.9141.95630297.64090-1.068102.311201.67980HepG2EIF4B
NR1H2ENSG00000131408.9111.03800174.44480-0.651702.696101.86740HepG2EIF4G1
NR1H2ENSG00000131408.9282.77780167.109000.758804.386503.37560HepG2EIF4G2
NR1H2ENSG00000131408.9657.42330429.370300.614506.119005.28530HepG2ETF1
NR1H2ENSG00000131408.9206.35810111.609800.886602.544901.42590HepG2FAM120A
NR1H2ENSG00000131408.960.00020124.28500-1.050603.368901.97340HepG2FKBP4
NR1H2ENSG00000131408.9444.89900286.061000.637102.731802.06980HepG2G3BP1
NR1H2ENSG00000131408.9376.66350272.854600.465003.305302.24280HepG2HDGF
NR1H2ENSG00000131408.9172.6997080.890501.094102.830402.17680HepG2HNRNPA1
NR1H2ENSG00000131408.9225.30500109.307401.043405.146303.21110HepG2HNRNPAB
NR1H2ENSG00000131408.9228.1058089.978501.342002.283401.64830HepG2HNRNPC
NR1H2ENSG00000131408.9268.73350188.848200.508802.933202.19610HepG2HNRNPF
NR1H2ENSG00000131408.9345.41510161.084801.1004012.3992011.06620HepG2HNRNPL
NR1H2ENSG00000131408.9346.30590161.618401.099403.735603.01390HepG2HNRNPLL
NR1H2ENSG00000131408.9231.0942089.383401.3703012.3243011.12060HepG2HNRNPU
NR1H2ENSG00000131408.9273.81930185.962700.558102.506801.81690HepG2IGF2BP1
NR1H2ENSG00000131408.9475.87950290.719900.710903.479202.73040HepG2IGF2BP2
NR1H2ENSG00000131408.9175.3040091.301700.941005.761004.73780HepG2ILF2
NR1H2ENSG00000131408.9241.92430126.134500.939502.571601.43360HepG2KHDRBS1
NR1H2ENSG00000131408.9487.99450317.599100.619602.042201.49380HepG2NCBP2
NR1H2ENSG00000131408.9410.59360175.346001.2274014.8340013.13440HepG2NOL12
NR1H2ENSG00000131408.9175.4355082.272101.092404.304702.52320HepG2NOLC1
NR1H2ENSG00000131408.9334.64060137.241601.285806.172204.49990HepG2NONO
NR1H2ENSG00000131408.9294.61850120.839701.285704.813303.61660HepG2PABPC1
NR1H2ENSG00000131408.9168.1492088.470800.926404.869403.78450HepG2PARN
NR1H2ENSG00000131408.9257.5211079.722401.6915018.0245016.25800HepG2PPIL4
NR1H2ENSG00000131408.9360.40290167.379501.106409.512608.49840HepG2PUF60
NR1H2ENSG00000131408.9391.66100177.676401.1403014.8035013.65870HepG2PUM1
NR1H2ENSG00000131408.9292.04420177.549300.717903.962303.16370HepG2PUM2
NR1H2ENSG00000131408.9326.98730111.237701.555507.851506.08980HepG2RCC2
NR1H2ENSG00000131408.9280.79570381.34850-0.441602.564002.04010HepG2NELFE
NR1H2ENSG00000131408.9253.77770355.19270-0.485002.913002.28220HepG2RECQL
NR1H2ENSG00000131408.9216.01000121.458300.830502.654202.05080HepG2RPS19
NR1H2ENSG00000131408.9233.04540132.902400.810102.689201.90060HepG2RPS3A
NR1H2ENSG00000131408.9249.5166079.598201.6482017.1580015.75020HepG2SAFB2
NR1H2ENSG00000131408.9584.02040278.055001.070509.495608.19010HepG2SF3A3
NR1H2ENSG00000131408.9290.79170160.482000.857506.996705.96200HepG2SLBP
NR1H2ENSG00000131408.9188.2104092.822201.019706.367005.45520HepG2SMN1
NR1H2ENSG00000131408.9310.96540141.602701.134804.429203.19860HepG2SMNDC1
NR1H2ENSG00000131408.9199.1523069.948801.509402.856001.52170HepG2SNRNP200
NR1H2ENSG00000131408.9169.04450372.37000-1.1393011.7943010.96330HepG2SRSF1
NR1H2ENSG00000131408.9313.12140165.257700.921908.063707.06690HepG2SRSF5
NR1H2ENSG00000131408.9295.80790185.533100.672904.965904.07520HepG2SRSF7
NR1H2ENSG00000131408.9190.92880302.95050-0.666004.750104.06380HepG2SRSF9
NR1H2ENSG00000131408.9319.72190214.126500.578302.704401.47880HepG2STAU1
NR1H2ENSG00000131408.9244.20380115.687201.077805.225203.66890HepG2STIP1
NR1H2ENSG00000131408.9345.27240187.947900.877308.094207.12470HepG2SUCLG1
NR1H2ENSG00000131408.9383.76700216.478800.825906.678505.25990HepG2SUPT6H
NR1H2ENSG00000131408.9285.64280148.641700.942304.007103.21590HepG2SUPV3L1
NR1H2ENSG00000131408.9100.96930334.72550-1.7291020.6133019.27950HepG2TAF15
NR1H2ENSG00000131408.9237.0599099.610101.250807.220605.74170HepG2TFIP11
NR1H2ENSG00000131408.9206.41850307.54080-0.575203.495602.56010HepG2TIA1
NR1H2ENSG00000131408.9287.9208086.842201.7291018.5158017.43330HepG2TIAL1
NR1H2ENSG00000131408.9303.2602087.629701.7910023.5972022.14900HepG2TRIM56
NR1H2ENSG00000131408.9343.81310163.515701.072109.233507.45660HepG2TUFM
NR1H2ENSG00000131408.9431.37200274.302300.653103.878103.13900HepG2U2AF1
NR1H2ENSG00000131408.9239.9939081.095001.565204.539303.25780HepG2U2AF2
NR1H2ENSG00000131408.9387.42210173.074201.162403.371302.44770HepG2UBE2L3
NR1H2ENSG00000131408.9153.8819087.785700.809702.848102.07800HepG2UCHL5
NR1H2ENSG00000131408.9382.17970246.591900.632005.347604.42780HepG2UPF1
NR1H2ENSG00000131408.9273.52620119.053501.200007.399205.61610HepG2XPO5
NR1H2ENSG00000131408.9513.36870271.204400.9205013.4371012.45820HepG2ZNF622
NR1H2ENSG00000131408.9946.34070749.979500.335403.273902.66590K562AGGF1
NR1H2ENSG00000131408.91703.217201094.145800.638406.762205.91000K562AQR
NR1H2ENSG00000131408.91048.48180818.816200.356603.558202.51020K562ATP5C1
NR1H2ENSG00000131408.9624.00550437.743800.511403.678802.12040K562BCCIP
NR1H2ENSG00000131408.9570.83100288.732000.983203.424401.98790K562CIRBP
NR1H2ENSG00000131408.9460.01270320.956800.519203.434002.23620K562CSTF2
NR1H2ENSG00000131408.91180.343801569.10640-0.410705.013703.69340K562CELF1
NR1H2ENSG00000131408.9842.39650494.589300.768203.732601.53470K562DDX1
NR1H2ENSG00000131408.9721.49050476.444100.598605.916704.32440K562DDX3X
NR1H2ENSG00000131408.91190.08180854.070000.478507.051706.07790K562DDX47
NR1H2ENSG00000131408.9639.65340483.035000.405103.264401.81480K562DDX6
NR1H2ENSG00000131408.9634.52480345.194600.878203.641002.14430K562EEF2
NR1H2ENSG00000131408.9512.88600333.405500.621302.356701.51590K562EFTUD2
NR1H2ENSG00000131408.9735.56790523.262500.491205.243203.55150K562EIF2S1
NR1H2ENSG00000131408.9546.07410356.773500.614002.421001.46000K562EIF3D
NR1H2ENSG00000131408.9308.63700168.041100.877006.550605.34130K562EIF3G
NR1H2ENSG00000131408.9680.07940448.217100.601405.435503.73620K562EIF4B
NR1H2ENSG00000131408.91545.560801275.953500.276502.546101.64050K562EIF4G2
NR1H2ENSG00000131408.9770.25030540.523600.510902.165101.41280K562FIP1L1
NR1H2ENSG00000131408.9152.62220352.70620-1.2085010.200607.85920K562FKBP4
NR1H2ENSG00000131408.938.31180128.58720-1.746908.348706.98310K562G3BP2
NR1H2ENSG00000131408.9695.44460405.876700.776808.248307.26640K562HNRNPC
NR1H2ENSG00000131408.9535.02560362.542800.561404.047002.63360K562HNRNPF
NR1H2ENSG00000131408.9770.96180269.730101.515002.806101.77290K562IGF2BP2
NR1H2ENSG00000131408.9472.47690274.215600.784803.988702.50040K562IGF2BP3
NR1H2ENSG00000131408.9360.06010589.31890-0.710803.505501.87460K562ILF2
NR1H2ENSG00000131408.9447.58050282.512500.663702.514801.63850K562MATR3
NR1H2ENSG00000131408.9588.38200329.009200.838503.790302.21930K562NONO
NR1H2ENSG00000131408.9473.19220888.00340-0.908109.749308.19330K562PCBP3
NR1H2ENSG00000131408.9380.56500681.13710-0.8398010.729909.19780K562POLR2G
NR1H2ENSG00000131408.9561.08470324.447100.790103.505102.66010K562PRPF8
NR1H2ENSG00000131408.9540.51570363.937300.570503.211502.22500K562PSIP1
NR1H2ENSG00000131408.9482.80660275.111700.811305.063604.18900K562PTBP1
NR1H2ENSG00000131408.91106.850401392.13190-0.330802.259801.52350K562PUF60
NR1H2ENSG00000131408.91120.961201480.96110-0.401804.600403.19860K562PUM1
NR1H2ENSG00000131408.9455.16420263.614900.787902.339801.57160K562RBM22
NR1H2ENSG00000131408.9479.27520257.115400.898304.071002.28570K562RBM34
NR1H2ENSG00000131408.9666.11700332.172101.0037013.3864011.21100K562RCC2
NR1H2ENSG00000131408.9577.41730330.338800.805602.206901.48070K562RPS19
NR1H2ENSG00000131408.9418.96430268.856700.639903.088402.02600K562RPS3
NR1H2ENSG00000131408.9465.81710627.45900-0.429802.746101.30890K562SDAD1
NR1H2ENSG00000131408.9207.47180133.671100.634103.202702.28240K562SF3B4
NR1H2ENSG00000131408.9548.35240314.877200.800207.323105.42930K562SRFBP1
NR1H2ENSG00000131408.9432.33560269.739100.680502.176401.54080K562SRSF1
NR1H2ENSG00000131408.9447.21750259.514900.785106.111904.43750K562SRSF4
NR1H2ENSG00000131408.9485.42540254.842100.929504.303802.94810K562SRSF5
NR1H2ENSG00000131408.9557.38360313.871900.828403.676502.49030K562SUPV3L1
NR1H2ENSG00000131408.9447.15400683.18690-0.611506.295505.05090K562SYNCRIP
NR1H2ENSG00000131408.9754.56080272.911901.4671016.6550014.62760K562TARDBP
NR1H2ENSG00000131408.9571.40850263.275801.1178010.349608.64520K562TIA1
NR1H2ENSG00000131408.9579.46140350.031400.727102.923601.96040K562TIAL1
NR1H2ENSG00000131408.9488.45690258.545200.917706.794204.89280K562TRA2A
NR1H2ENSG00000131408.9582.63610372.004300.647205.385603.96250K562TRIM56
NR1H2ENSG00000131408.9790.70760945.12480-0.257402.365901.57870K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NR1H2 is not available on ENCORE database.





1 RBPs can affect the splicing of NR1H2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSNR1H2ENSG00000131408.9chr19+5088080950880905508808435088090550879975508800830.156000.000000.00000longerK562AQR
RINR1H2ENSG00000131408.9chr19+5087972950880083508797295087983350879975508800830.090000.000000.00000includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NR1H2 is not avaliable on ENCORE database.