NELFB

General Information

Gene Name       : NELFB
Gene ID             : ENSG00000188986.6
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: NELFB)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NELFBENSG00000188986.63.1312.367.74ENCSR000AEF
HepG2NELFBENSG00000188986.645.2915.2330.26ENCSR985KAT
K562NELFBENSG00000188986.638.1919.0728.63ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NELFB is not avaliable on ENCORE database.



Proteins bound to RNA
  • NELFB RNA is bound by 35 proteins.  







eCLIP assay for NELFB is not avaliable on ENCORE database.





35 proteins are bound to NELFB RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr9140167750140167834+3'-UTR5.7656612.69138K562UPF1
chr9140167852140167944+3'-UTR3.192143.52299HepG2AKAP1
chr9140167672140167758+3'-UTR3.614208.24027K562DDX55
chr9140167346140167441+3'-UTR,CDS4.325279.87725HepG2UPF1
chr9140167672140167752+3'-UTR4.295248.34313K562DDX6
chr9140167535140167592+3'-UTR5.256179.46220HepG2UPF1
chr9140167667140167739+3'-UTR3.340993.26413K562ZC3H11A
chr9140167385140167476+3'-UTR4.011093.72123HepG2AKAP1
chr9140167751140167834+3'-UTR4.445624.92727HepG2AKAP1
chr9140167827140167861+3'-UTR4.039536.57313K562PABPC4
chr9140167875140167939+3'-UTR4.000517.11247HepG2UPF1
chr9140167764140167825+3'-UTR5.220979.75816HepG2UPF1
chr9140167668140167755+3'-UTR5.5417410.64766HepG2UPF1
chr9140167674140167749+3'-UTR3.592603.38753K562FAM120A
chr9140167907140167976+3'-UTR4.442807.04643K562PUM2
chr9140167550140167609+3'-UTR3.363176.37005K562UPF1
chr9140167747140167827+3'-UTR4.721548.50867K562PABPC4
chr9140167834140167943+3'-UTR4.010188.04798K562UPF1
chr9140167669140167793+3'-UTR3.320879.78821HepG2DDX55
chr9140167825140167875+3'-UTR4.811266.96152HepG2UPF1
chr9140167678140167731+3'-UTR3.087513.27723HepG2AKAP1
chr9140167473140167535+3'-UTR4.535559.06961HepG2UPF1
chr9140167681140167750+3'-UTR4.6638910.92855K562UPF1
chr9140149882140149982+5'-UTR,CDS4.1062720.45660K562GEMIN5
chr9140149785140149832+5'-UTR3.3338213.44373HepG2DDX3X
chr9140149905140149984+5'-UTR,CDS3.718296.02920HepG2PRPF4
chr9140149887140150015+5'-UTR,CDS3.232277.35441HepG2GRSF1
chr9140149754140149868+5'-UTR3.170019.33311K562NCBP2
chr9140149832140149884+5'-UTR3.9239816.10838HepG2DDX3X
chr9140149757140149873+5'-UTR3.756617.70534HepG2PRPF4
chr9140149898140150003+5'-UTR,CDS3.9656936.56605HepG2DDX3X
chr9140149764140149858+5'-UTR4.444664.42691HepG2GTF2F1
chr9140149744140149815+5'-UTR3.033653.65608HepG2RBFOX2
chr9140149910140149979+5'-UTR,CDS3.1338010.88164K562DDX24
chr9140149765140149888+5'-UTR5.4110710.01529HepG2NCBP2
chr9140149876140149974+5'-UTR,CDS3.729695.23852K562DDX3X
chr9140151231140151297+CDS,intron-Proximal4.507524.92499HepG2AQR
chr9140161351140161405+CDS,intron-Proximal4.478664.28193HepG2AQR
chr9140160794140160824+CDS3.512365.58370HepG2PPIG
chr9140166479140166545+CDS,intron-Proximal4.6065211.40024HepG2SF3B4
chr9140161789140161845+CDS,intron-Proximal3.132174.71929HepG2PRPF8
chr9140161355140161413+CDS,intron-Proximal3.647725.14244K562DROSHA
chr9140151275140151286+CDS,intron-Proximal3.647443.32039HepG2PPIG
chr9140161747140161793+CDS4.069333.83925K562YBX3
chr9140151488140151506+CDS3.884004.66686K562DDX24
chr9140157488140157505+CDS,intron-Proximal3.627125.86107HepG2PPIG
chr9140158647140158700+CDS,intron-Proximal3.940517.30826HepG2SF3B4
chr9140150810140150879+CDS3.443475.10493HepG2AQR
chr9140166669140166717+CDS,intron-Proximal3.315224.22621HepG2PRPF8
chr9140150787140150820+CDS3.835204.97821K562BUD13
chr9140151482140151506+CDS3.423924.51003HepG2PPIG
chr9140158759140158810+CDS,intron-Proximal3.390545.08732HepG2PPIG
chr9140151309140151337+CDS3.264974.24993HepG2PPIG
chr9140150808140150882+CDS,intron-Proximal3.531787.60977HepG2PPIG
chr9140150752140150786+CDS,intron-Proximal4.422564.92499HepG2AQR
chr9140150058140150127+CDS,intron-Proximal4.8912213.47152HepG2PRPF8
chr9140161323140161397+CDS,intron-Proximal5.185619.69835HepG2PRPF4
chr9140151342140151415+CDS3.925103.43526K562GRWD1
chr9140150518140150559+CDS,intron-Proximal4.235954.27476HepG2AQR
chr9140160910140160981+intron-Distal,intron-Proximal3.223276.95640HepG2RBFOX2
chr9140157914140158041+intron-Distal3.639254.59821K562ILF3
chr9140160921140161007+intron-Distal,intron-Proximal4.4324011.61767HepG2PRPF4
chr9140165505140165636+intron-Distal4.833786.40665K562NONO
chr9140158197140158307+intron-Distal4.090613.34601K562HNRNPK
chr9140160930140160995+intron-Distal,intron-Proximal3.140793.62708K562CSTF2T
chr9140157876140157983+intron-Distal6.2117728.47642HepG2DDX59
chr9140161084140161176+intron-Distal4.510454.53244K562HNRNPM
chr9140160667140160705+intron-Distal,intron-Proximal4.163464.32536HepG2SF3B4
chr9140160916140161002+intron-Distal,intron-Proximal3.194373.69530HepG2CSTF2T
chr9140165924140166047+intron-Distal3.224704.83226HepG2HNRNPM
chr9140158186140158315+intron-Distal4.0407310.67605HepG2DDX59
chr9140161279140161334+intron-Distal,intron-Proximal4.301186.85082HepG2FAM120A
chr9140157721140157789+intron-Distal,intron-Proximal5.525089.83537HepG2PCBP2
chr9140166247140166339+intron-Distal3.608514.09699HepG2HNRNPK
chr9140160957140160987+intron-Distal,intron-Proximal3.998104.49024K562AQR
chr9140157381140157483+intron-Distal,intron-Proximal4.120713.82050HepG2SF3B4
chr9140161276140161390+intron-Distal,intron-Proximal3.552427.29501HepG2RBFOX2
chr9140160958140161024+intron-Distal,intron-Proximal4.265436.71940K562PRPF8
chr9140157917140157983+intron-Distal3.869943.06617K562HNRNPK
chr9140160912140161018+intron-Distal,intron-Proximal3.905305.97419K562RBFOX2
chr9140160652140160744+intron-Distal,intron-Proximal3.641543.60408HepG2XPO5
chr9140157791140157889+intron-Distal6.1425912.91829HepG2PCBP2
chr9140161292140161382+intron-Distal,intron-Proximal4.563745.84876HepG2GTF2F1
chr9140161247140161317+intron-Distal,intron-Proximal4.832335.84281K562GTF2F1
chr9140160933140161089+intron-Distal,intron-Proximal5.9378111.61399K562GTF2F1
chr9140157893140158037+intron-Distal3.586558.07504HepG2HNRNPK
chr9140160563140160606+intron-Distal3.321843.61733HepG2XPO5
chr9140161827140161909+intron-Distal,intron-Proximal6.8089823.70045HepG2RBM22
chr9140160664140160705+intron-Distal,intron-Proximal5.361688.26501K562SF3B4
chr9140157728140157826+intron-Distal,intron-Proximal4.897647.72290HepG2HNRNPK
chr9140157889140157980+intron-Distal5.5828223.00862HepG2PCBP2
chr9140166195140166331+intron-Distal4.4814613.11176HepG2PCBP2
chr9140157983140158038+intron-Distal4.7935515.14188HepG2DDX59
chr9140164174140164241+intron-Distal6.2175411.24011HepG2XPO5
chr9140166331140166402+intron-Distal5.243628.17201HepG2PCBP2
chr9140161338140161392+intron-Proximal3.415294.25667K562CSTF2T
chr9140151238140151267+intron-Proximal4.408234.69223K562SF3B4
chr9140150880140150924+intron-Proximal4.473858.01338K562AQR
chr9140150534140150575+intron-Proximal4.395798.79285K562AQR
chr9140150525140150580+intron-Proximal3.130953.94281K562PRPF8
chr9140150549140150582+intron-Proximal4.161094.07072K562UCHL5
chr9140151216140151238+intron-Proximal5.443075.90023K562SF3B4
chr9140151529140151586+intron-Proximal3.365924.31340HepG2RBM22
chr9140161350140161394+intron-Proximal4.074154.12529K562GTF2F1
chr9140151198140151240+intron-Proximal4.869947.23689K562BUD13
chr9140161334140161387+intron-Proximal4.170128.26134HepG2FAM120A
chr9140150522140150534+intron-Proximal3.997436.80869K562AQR
chr9140161327140161387+intron-Proximal4.202774.14056K562EWSR1
chr9140151510140151549+intron-Proximal5.082405.65342K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NELFB is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NELFB is not available on ENCORE database.

  • 79 RBPs can affect the levels of NELFB.  








The Knockdown/knockout RNA-Seq assay for NELFB is not available on ENCORE database.





79 RBPs can affect the gene expression of NELFB :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NELFBENSG00000188986.4395.09560676.26970-0.775407.796506.10790HepG2AATF
NELFBENSG00000188986.41071.924401233.64220-0.202701.874201.35600HepG2ACO1
NELFBENSG00000188986.4728.560201202.91400-0.723402.416501.67710HepG2ASCC1
NELFBENSG00000188986.41930.919801651.403500.225502.364101.72050HepG2AUH
NELFBENSG00000188986.4298.28260467.68610-0.648904.970703.97360HepG2CALR
NELFBENSG00000188986.4352.69930469.63270-0.413102.259401.62970HepG2CPSF6
NELFBENSG00000188986.4385.21900692.66010-0.846506.497204.14300HepG2CSTF2T
NELFBENSG00000188986.4711.90520841.11280-0.240601.850701.30500HepG2CELF1
NELFBENSG00000188986.4506.23180745.57020-0.558503.805203.02240HepG2DDX21
NELFBENSG00000188986.4424.37100730.06240-0.782709.143807.51660HepG2DDX24
NELFBENSG00000188986.42009.826701196.880600.747704.547403.77190HepG2DDX6
NELFBENSG00000188986.4983.013001180.22510-0.263802.453401.80900HepG2DKC1
NELFBENSG00000188986.4628.44660463.489800.439204.733203.91750HepG2DNAJC2
NELFBENSG00000188986.4418.67610686.95300-0.714405.199803.68190HepG2AGO1
NELFBENSG00000188986.4366.94330551.87890-0.588803.139902.18290HepG2EIF3D
NELFBENSG00000188986.4541.59420704.38060-0.379102.744401.66610HepG2EIF3G
NELFBENSG00000188986.4606.70840892.26000-0.556507.295206.05100HepG2EIF4G1
NELFBENSG00000188986.41642.384401896.12980-0.207302.332801.77250HepG2ETF1
NELFBENSG00000188986.4496.07410710.74580-0.518804.415003.02090HepG2FASTKD2
NELFBENSG00000188986.4606.42640927.24750-0.612606.524705.34510HepG2FUBP3
NELFBENSG00000188986.4717.295201189.49700-0.729702.541801.90210HepG2G3BP1
NELFBENSG00000188986.41047.94950823.950700.346804.102403.29420HepG2HNRNPL
NELFBENSG00000188986.4390.66730508.01180-0.378901.919801.38710HepG2HNRNPLL
NELFBENSG00000188986.4705.419901216.30550-0.786002.714101.72220HepG2KHSRP
NELFBENSG00000188986.4789.36800604.850000.384002.363501.32000HepG2LARP7
NELFBENSG00000188986.41271.04420896.888100.502906.231605.09010HepG2NOL12
NELFBENSG00000188986.4706.98510465.237100.603607.097705.95880HepG2PPIL4
NELFBENSG00000188986.4424.63960692.78540-0.706209.500008.19220HepG2PRPF4
NELFBENSG00000188986.41090.23290856.133300.348602.582602.00430HepG2PUF60
NELFBENSG00000188986.41282.71760908.794000.497109.079108.13640HepG2PUM1
NELFBENSG00000188986.41009.512501256.52410-0.315803.847003.14450HepG2PUS1
NELFBENSG00000188986.41015.497401402.53180-0.465802.212201.64270HepG2QKI
NELFBENSG00000188986.41023.959801584.79330-0.6301011.4582010.55650HepG2RBM22
NELFBENSG00000188986.4820.89020592.283000.470802.798301.73230HepG2RCC2
NELFBENSG00000188986.4382.05110537.07280-0.491402.989902.35500HepG2RPS19
NELFBENSG00000188986.4726.88640464.513500.645909.200508.13410HepG2SAFB2
NELFBENSG00000188986.4341.30130538.92490-0.659005.316404.02290HepG2SERBP1
NELFBENSG00000188986.41031.97360820.838400.330102.238901.59670HepG2SLBP
NELFBENSG00000188986.4661.80340541.686800.288802.341201.74270HepG2SMN1
NELFBENSG00000188986.4215.35200559.47080-1.3774011.516009.93840HepG2SNRNP70
NELFBENSG00000188986.41397.759101789.92970-0.356805.878605.22400HepG2SRFBP1
NELFBENSG00000188986.4794.994501407.42390-0.824007.281206.59860HepG2SRSF1
NELFBENSG00000188986.41124.03150845.271900.411105.004104.20190HepG2SRSF5
NELFBENSG00000188986.4727.798101145.08710-0.653805.974005.21840HepG2SRSF9
NELFBENSG00000188986.41264.361001554.01990-0.297603.867303.28350HepG2SSB
NELFBENSG00000188986.41282.46800961.337000.415706.033205.17900HepG2SUCLG1
NELFBENSG00000188986.4433.65840742.64590-0.776102.541401.89000HepG2SUPV3L1
NELFBENSG00000188986.4485.080501265.28190-1.3832015.2838014.12440HepG2TAF15
NELFBENSG00000188986.4351.57710495.25920-0.494303.078602.31910HepG2TARDBP
NELFBENSG00000188986.4751.518401162.37300-0.629203.343002.42800HepG2TIA1
NELFBENSG00000188986.4705.47760511.381600.464105.011804.29760HepG2TRIM56
NELFBENSG00000188986.41176.79950836.358200.492603.549502.54670HepG2TUFM
NELFBENSG00000188986.4476.31360839.22960-0.817205.792404.90070HepG2U2AF1
NELFBENSG00000188986.41291.24670885.240700.544502.066501.34920HepG2UBE2L3
NELFBENSG00000188986.4399.26280683.68740-0.7760012.0516010.81610HepG2ZC3H8
NELFBENSG00000188986.41888.635701135.443000.7340016.4373015.17730K562AGGF1
NELFBENSG00000188986.41663.968201247.716300.415203.481002.34810K562AKAP8
NELFBENSG00000188986.41610.782201181.488800.447104.060803.26860K562AKAP8L
NELFBENSG00000188986.41268.283201950.48470-0.621007.319706.43880K562AQR
NELFBENSG00000188986.41115.02900863.179500.369204.009302.83730K562BCLAF1
NELFBENSG00000188986.4956.89770654.850600.547106.048004.40340K562CSTF2
NELFBENSG00000188986.42075.345002616.42490-0.334204.282003.05970K562CELF1
NELFBENSG00000188986.4978.07500756.708000.370103.828102.24200K562DDX27
NELFBENSG00000188986.41427.260601137.881700.326803.566802.03160K562DDX6
NELFBENSG00000188986.4459.54760645.02800-0.489103.484601.96390K562DNAJC21
NELFBENSG00000188986.4607.72120448.115600.439403.644502.73940K562EIF3G
NELFBENSG00000188986.41271.561701023.533600.312902.909701.57990K562EWSR1
NELFBENSG00000188986.4835.85860658.551300.343902.341901.56200K562FIP1L1
NELFBENSG00000188986.4122.31490347.37300-1.5059012.9560011.18360K562G3BP2
NELFBENSG00000188986.41262.99620640.051400.980503.728302.46830K562IGF2BP2
NELFBENSG00000188986.41173.08230671.750300.804204.504503.42490K562MAGOH
NELFBENSG00000188986.41775.953802267.54790-0.352503.546702.26680K562MSI2
NELFBENSG00000188986.4742.074201062.29820-0.517602.304201.54570K562PCBP3
NELFBENSG00000188986.41084.19670747.672600.536005.221104.03660K562PPIG
NELFBENSG00000188986.41123.70720652.716200.783603.535802.79620K562PTBP1
NELFBENSG00000188986.42091.849802469.41560-0.239402.628101.59050K562PUM1
NELFBENSG00000188986.41542.482801171.649400.396603.516202.91530K562PUS1
NELFBENSG00000188986.41516.621501141.648300.409604.718003.96380K562RBM15
NELFBENSG00000188986.4539.82680361.028400.580305.161303.97410K562SF3B4
NELFBENSG00000188986.4280.74440411.47760-0.551603.460901.64590K562SND1
NELFBENSG00000188986.4984.89990639.982600.621802.217301.57560K562SRSF1
NELFBENSG00000188986.41004.66780604.670500.732403.383302.20230K562SRSF5
NELFBENSG00000188986.4189.45680340.97260-0.847802.847201.35980K562TAF15
NELFBENSG00000188986.41178.61730647.481900.864104.024903.16440K562TARDBP
NELFBENSG00000188986.41166.22500624.627800.900704.991203.84140K562TIA1
NELFBENSG00000188986.41119.59520613.471600.867803.993302.64290K562TRA2A
NELFBENSG00000188986.4189.46570336.51670-0.828704.257602.84140K562U2AF1
NELFBENSG00000188986.4165.05650347.61410-1.0745010.497108.93170K562U2AF2
NELFBENSG00000188986.4971.643601210.25800-0.316803.905202.91100K562WDR43
NELFBENSG00000188986.4619.225901042.53670-0.751603.169601.43740K562YTHDC2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NELFB is not available on ENCORE database.





2 RBPs can affect the splicing of NELFB :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENELFBENSG00000188986.4chr9+140161691140161798140160782140160878140166532140166674-0.159000.004290.06702excludedHepG2U2AF1
A3SSNELFBENSG00000188986.4chr9+1401669381401670671401669581401670671401665321401666740.053000.000010.00006longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NELFB is not avaliable on ENCORE database.