MRPL3

General Information

Gene Name       : MRPL3
Gene ID             : ENSG00000114686.8
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MRPL3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MRPL3ENSG00000114686.8222.68209.18215.93ENCSR000AEF
HepG2MRPL3ENSG00000114686.897.59163.36130.48ENCSR985KAT
K562MRPL3ENSG00000114686.8154.05228.68191.37ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MRPL3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MRPL3 RNA is bound by 12 proteins.  







eCLIP assay for MRPL3 is not avaliable on ENCORE database.





12 proteins are bound to MRPL3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3131181411131181509-3'-UTR,intron-Distal3.906536.79446K562IGF2BP1
chr3131181531131181711-3'-UTR,CDS,intron-Distal3.568804.31813HepG2G3BP1
chr3131181425131181616-3'-UTR,CDS,intron-Distal4.5724218.41748K562YBX3
chr3131221606131221672-5'-UTR,CDS,intron-Distal3.2474312.35407K562DDX3X
chr3131221682131221764-5'-UTR,CDS,intron-Distal6.377436.75859HepG2DDX3X
chr3131221672131221808-5'-UTR,CDS,intron-Distal,intron-Proximal4.3138025.82588K562DDX3X
chr3131221570131221664-5'-UTR,CDS,intron-Distal4.2855616.10838HepG2DDX3X
chr3131221573131221618-CDS,intron-Distal3.771499.49061K562TROVE2
chr3131219226131219289-CDS,intron-Distal,intron-Proximal3.813424.23459K562PRPF8
chr3131219240131219323-CDS,intron-Distal,intron-Proximal3.867365.43815HepG2PRPF8
chr3131217015131217115-CDS,intron-Distal,intron-Proximal4.365277.09561HepG2BCLAF1
chr3131190014131190038-CDS,intron-Distal,intron-Proximal4.185268.28294K562YBX3
chr3131190038131190055-CDS,intron-Distal5.4159411.11497K562YBX3
chr3131181623131181674-CDS,intron-Distal3.582215.00403K562IGF2BP1
chr3131208865131208915-CDS,intron-Distal,intron-Proximal3.530343.68471HepG2BCLAF1
chr3131216939131217024-CDS,intron-Distal,intron-Proximal4.676915.82778K562PRPF8
chr3131188502131188581-CDS,intron-Distal,intron-Proximal5.027023.70131HepG2PRPF8
chr3131190055131190100-CDS,intron-Distal3.401518.20394K562YBX3
chr3131190018131190070-CDS,intron-Distal3.734403.11149HepG2G3BP1
chr3131193197131193289-intron-Distal4.6100713.04492HepG2QKI
chr3131198039131198071-intron-Distal5.24287400.00000HepG2DKC1
chr3131198028131198032-intron-Distal5.51391400.00000HepG2DKC1
chr3131198004131198008-intron-Distal5.93899400.00000HepG2DKC1
chr3131198032131198036-intron-Distal5.47964400.00000HepG2DKC1
chr3131197972131197983-intron-Distal5.91504400.00000HepG2DKC1
chr3131197951131197972-intron-Distal5.85809400.00000HepG2DKC1
chr3131186035131186110-intron-Distal3.508134.82429K562TARDBP
chr3131193207131193295-intron-Distal4.9235520.73523HepG2PCBP2
chr3131198017131198025-intron-Distal5.45770400.00000HepG2DKC1
chr3131212924131212986-intron-Distal3.320193.68481HepG2HNRNPM
chr3131215104131215187-intron-Distal3.974753.16986HepG2QKI
chr3131198008131198016-intron-Distal5.56060400.00000HepG2DKC1
chr3131198071131198077-intron-Distal4.74185400.00000HepG2DKC1
chr3131197983131197990-intron-Distal5.90813400.00000HepG2DKC1
chr3131197990131198004-intron-Distal5.87492400.00000HepG2DKC1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MRPL3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MRPL3 is not available on ENCORE database.

  • 104 RBPs can affect the levels of MRPL3.  








The Knockdown/knockout RNA-Seq assay for MRPL3 is not available on ENCORE database.





104 RBPs can affect the gene expression of MRPL3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MRPL3ENSG00000114686.41205.046301517.66770-0.332804.672803.92150HepG2ACO1
MRPL3ENSG00000114686.41134.964201748.95190-0.623806.603605.41530HepG2ASCC1
MRPL3ENSG00000114686.41816.152802638.85990-0.5390012.5116011.23790HepG2AUH
MRPL3ENSG00000114686.4977.178601428.55390-0.547904.588903.45480HepG2BCLAF1
MRPL3ENSG00000114686.41722.846302337.75990-0.440304.619703.87010HepG2BOP1
MRPL3ENSG00000114686.41269.593201610.95420-0.343502.969101.69560HepG2BUD13
MRPL3ENSG00000114686.41697.365102636.16010-0.635105.595404.18530HepG2CCAR1
MRPL3ENSG00000114686.41265.808101661.62150-0.392503.014502.20850HepG2CIRBP
MRPL3ENSG00000114686.4834.225002146.23180-1.3633030.8324028.87610HepG2CPSF6
MRPL3ENSG00000114686.41865.186702248.75140-0.269804.611003.69150HepG2DAZAP1
MRPL3ENSG00000114686.4607.142401282.29130-1.0786019.7187018.11030HepG2DDX21
MRPL3ENSG00000114686.42594.409702024.823800.357502.684502.06710HepG2DDX3X
MRPL3ENSG00000114686.41175.436301616.45880-0.459603.312202.47670HepG2DDX55
MRPL3ENSG00000114686.41742.786302437.19040-0.483802.317401.42560HepG2DDX59
MRPL3ENSG00000114686.41174.579201739.31560-0.566404.752203.96220HepG2DDX6
MRPL3ENSG00000114686.41139.232201451.99820-0.350004.413703.59420HepG2DKC1
MRPL3ENSG00000114686.41246.251401522.68260-0.289004.097503.33480HepG2DNAJC2
MRPL3ENSG00000114686.41140.938401672.09580-0.551405.178804.38200HepG2EIF2S1
MRPL3ENSG00000114686.41192.082101847.88640-0.632405.980905.04410HepG2EIF4A3
MRPL3ENSG00000114686.42110.861103029.78710-0.5214012.4283011.30340HepG2ETF1
MRPL3ENSG00000114686.41201.758201729.51230-0.525204.539903.69680HepG2G3BP1
MRPL3ENSG00000114686.4797.598401065.06220-0.417202.979302.04730HepG2GEMIN5
MRPL3ENSG00000114686.4879.068501286.49940-0.549404.473803.17040HepG2GNB2L1
MRPL3ENSG00000114686.41355.241002433.03280-0.8442011.206209.98490HepG2GPKOW
MRPL3ENSG00000114686.41139.738901550.94920-0.444404.667203.85730HepG2HNRNPA1
MRPL3ENSG00000114686.4861.958601725.14970-1.0010018.5832016.95770HepG2HNRNPC
MRPL3ENSG00000114686.41682.601402316.19620-0.461108.658907.48060HepG2HNRNPF
MRPL3ENSG00000114686.41827.430202048.48820-0.164702.085801.48990HepG2HNRNPL
MRPL3ENSG00000114686.41192.751702321.87790-0.9610016.1468014.80120HepG2HNRNPLL
MRPL3ENSG00000114686.41218.814001713.74370-0.491709.265508.20440HepG2HNRNPU
MRPL3ENSG00000114686.41642.545402280.80100-0.473606.477105.41180HepG2IGF2BP1
MRPL3ENSG00000114686.41268.250801758.02500-0.471104.105603.29810HepG2IGF2BP2
MRPL3ENSG00000114686.41333.567801750.53150-0.392507.685106.52740HepG2ILF2
MRPL3ENSG00000114686.41191.500801387.34210-0.219502.429001.47300HepG2KIF1C
MRPL3ENSG00000114686.42017.430802782.43340-0.463803.404502.48320HepG2LARP4
MRPL3ENSG00000114686.41437.221601865.01790-0.375902.752902.09990HepG2MAGOH
MRPL3ENSG00000114686.41218.434901875.46800-0.622205.869104.97610HepG2MATR3
MRPL3ENSG00000114686.41535.267402367.76910-0.625004.666503.38740HepG2MTPAP
MRPL3ENSG00000114686.4813.850402229.84880-1.4541054.3556051.44390HepG2NOL12
MRPL3ENSG00000114686.41586.196202058.70760-0.376203.301702.48450HepG2NSUN2
MRPL3ENSG00000114686.41237.812601709.62240-0.465903.865403.02280HepG2PABPC4
MRPL3ENSG00000114686.4885.686301815.46770-1.0355034.3074032.57920HepG2PCBP1
MRPL3ENSG00000114686.41516.238801756.00740-0.211802.135001.44780HepG2PRPF4
MRPL3ENSG00000114686.41438.147901847.30940-0.361204.882804.19970HepG2PTBP1
MRPL3ENSG00000114686.41530.172302257.87160-0.561309.456308.25480HepG2PUM2
MRPL3ENSG00000114686.41190.593501545.84380-0.376705.813904.98040HepG2PUS1
MRPL3ENSG00000114686.41278.128402000.67520-0.6465012.1168010.94440HepG2QKI
MRPL3ENSG00000114686.41800.146102532.33660-0.492408.971508.16100HepG2RBM22
MRPL3ENSG00000114686.41282.070701815.74380-0.502106.318905.33730HepG2RBM25
MRPL3ENSG00000114686.41040.704801519.79750-0.546305.332603.94180HepG2RBM27
MRPL3ENSG00000114686.41536.858702055.87540-0.419807.011906.21940HepG2NELFE
MRPL3ENSG00000114686.41508.718401914.77320-0.343804.941904.14870HepG2RECQL
MRPL3ENSG00000114686.41603.169802494.97650-0.638109.174008.04580HepG2RPLP0
MRPL3ENSG00000114686.41669.782802298.26510-0.460904.801003.89300HepG2SF3B1
MRPL3ENSG00000114686.41463.887501923.28200-0.393806.192105.36670HepG2SF3B4
MRPL3ENSG00000114686.41605.366202040.83480-0.346306.403505.40640HepG2SLBP
MRPL3ENSG00000114686.41505.363101779.75650-0.241603.224002.53820HepG2SMN1
MRPL3ENSG00000114686.41890.972802557.19970-0.435402.351501.63370HepG2SNRNP70
MRPL3ENSG00000114686.41274.971902860.17260-1.1656057.2687055.74930HepG2SRFBP1
MRPL3ENSG00000114686.41650.812302101.56390-0.348305.492204.65390HepG2SRSF5
MRPL3ENSG00000114686.41569.517702275.55520-0.5359011.4996010.24670HepG2SRSF7
MRPL3ENSG00000114686.41051.768201633.20380-0.6349014.6686013.57830HepG2SRSF9
MRPL3ENSG00000114686.41864.500702483.29230-0.413507.573606.80690HepG2SSB
MRPL3ENSG00000114686.41347.706902390.10970-0.8266030.8696029.17140HepG2SUCLG1
MRPL3ENSG00000114686.4780.387301466.10400-0.9097016.5463014.40790HepG2SUPT6H
MRPL3ENSG00000114686.4741.573601609.15440-1.1176016.3312014.92910HepG2SUPV3L1
MRPL3ENSG00000114686.41437.669401804.41850-0.327803.851303.20860HepG2TAF15
MRPL3ENSG00000114686.41071.604602262.81540-1.0783021.8880020.21530HepG2TARDBP
MRPL3ENSG00000114686.41375.132801658.00820-0.269902.274001.51420HepG2TIA1
MRPL3ENSG00000114686.4689.308701665.20150-1.2725035.8244034.39690HepG2TIAL1
MRPL3ENSG00000114686.41346.385101680.10940-0.319504.391503.71390HepG2TRIM56
MRPL3ENSG00000114686.41500.332102200.96960-0.552905.135503.97450HepG2UBE2L3
MRPL3ENSG00000114686.4737.62970950.57330-0.365902.338001.63910HepG2UCHL5
MRPL3ENSG00000114686.41296.102401625.19180-0.326404.536403.67790HepG2UPF1
MRPL3ENSG00000114686.4747.157801473.47830-0.9797010.014908.04750HepG2UPF2
MRPL3ENSG00000114686.41933.231001569.053400.301004.113303.40520HepG2UTP3
MRPL3ENSG00000114686.41209.806001584.03620-0.388802.879602.14030HepG2XRN2
MRPL3ENSG00000114686.41194.413801732.95960-0.5369012.1497010.91000HepG2ZC3H8
MRPL3ENSG00000114686.4893.497301787.39490-1.0003040.0091038.56350HepG2ZNF622
MRPL3ENSG00000114686.44521.106005579.39160-0.303402.747201.52900K562ABCF1
MRPL3ENSG00000114686.42767.165204329.67580-0.6459010.633009.59370K562AQR
MRPL3ENSG00000114686.42026.032802433.30430-0.264303.729402.60700K562BCLAF1
MRPL3ENSG00000114686.42217.245703381.08930-0.608704.594203.45910K562BOP1
MRPL3ENSG00000114686.41978.223203595.12090-0.8618021.0071018.82160K562CPSF6
MRPL3ENSG00000114686.42623.381103093.96310-0.238003.057801.78240K562DDX21
MRPL3ENSG00000114686.45756.732004414.431900.382908.449407.39170K562DDX47
MRPL3ENSG00000114686.44305.688803297.507400.384806.613805.17100K562DKC1
MRPL3ENSG00000114686.42329.354303671.48450-0.6564017.5503015.96560K562EIF2S2
MRPL3ENSG00000114686.42336.184401935.863000.271102.886102.07480K562EIF3G
MRPL3ENSG00000114686.41665.572102001.12060-0.264802.020501.31640K562EIF4A3
MRPL3ENSG00000114686.42497.078403657.84800-0.550807.242305.82330K562FMR1
MRPL3ENSG00000114686.42114.126003100.31170-0.552406.142304.72610K562FTO
MRPL3ENSG00000114686.42860.114402081.076600.458608.590707.59560K562FXR1
MRPL3ENSG00000114686.43026.587302112.058400.518903.948803.06790K562G3BP2
MRPL3ENSG00000114686.41539.473002054.87310-0.416603.290401.71820K562GEMIN5
MRPL3ENSG00000114686.42362.382703432.49790-0.539007.736206.40360K562GPKOW
MRPL3ENSG00000114686.41560.746302897.88190-0.8928012.4398011.24990K562HNRNPC
MRPL3ENSG00000114686.41916.806302587.43460-0.432803.631302.30820K562HNRNPF
MRPL3ENSG00000114686.42989.172502290.188400.384203.321601.95380K562HNRNPK
MRPL3ENSG00000114686.44550.785503298.673400.464104.308503.13180K562HNRNPM
MRPL3ENSG00000114686.42214.794302930.81440-0.404102.583301.68500K562KRR1
MRPL3ENSG00000114686.41890.321503350.48320-0.8257017.2177014.95310K562METAP2
MRPL3ENSG00000114686.42734.389203265.86090-0.256204.100503.13230K562MTPAP
MRPL3ENSG00000114686.44481.659706119.10290-0.449305.352703.22830K562NOL12
MRPL3ENSG00000114686.42708.165403628.80010-0.4222014.2924012.78040K562NSUN2
MRPL3ENSG00000114686.42127.930302852.66140-0.422903.905202.08760K562NUSAP1
MRPL3ENSG00000114686.41929.731702886.25160-0.580806.356105.09330K562PCBP3
MRPL3ENSG00000114686.41600.747902213.77480-0.467806.404705.19240K562POLR2G
MRPL3ENSG00000114686.42853.970201994.529900.516806.134405.01700K562PRPF8
MRPL3ENSG00000114686.41756.762402598.14970-0.564606.532505.04700K562PSIP1
MRPL3ENSG00000114686.44901.211906361.40510-0.376206.752905.23470K562PUM2
MRPL3ENSG00000114686.41874.575202369.96870-0.338303.576602.45040K562RCC2
MRPL3ENSG00000114686.42621.002303580.49830-0.450009.202007.78000K562SF3A3
MRPL3ENSG00000114686.42286.603203264.27350-0.513604.960503.63120K562SF3B1
MRPL3ENSG00000114686.43052.379203668.27970-0.265205.069403.84910K562SRPK2
MRPL3ENSG00000114686.41937.457302295.12650-0.244402.062301.44150K562SRSF1
MRPL3ENSG00000114686.41763.289402167.46160-0.297702.376301.41430K562SRSF5
MRPL3ENSG00000114686.42163.799202761.15600-0.351705.518103.85310K562SRSF7
MRPL3ENSG00000114686.43928.719805325.80290-0.438906.985904.77050K562SUCLG1
MRPL3ENSG00000114686.41260.203201931.51080-0.616106.039304.49410K562SUPV3L1
MRPL3ENSG00000114686.43055.705402220.582500.460506.902805.59220K562SYNCRIP
MRPL3ENSG00000114686.41910.126202322.91570-0.282302.028401.41660K562TARDBP
MRPL3ENSG00000114686.41837.971002240.68880-0.285802.656801.85630K562TIA1
MRPL3ENSG00000114686.41500.172702499.04680-0.736207.912406.26300K562TIAL1
MRPL3ENSG00000114686.42049.714602654.34920-0.372903.530602.43680K562TRIM56
MRPL3ENSG00000114686.43735.320204691.85300-0.328902.835201.43120K562TRIP6
MRPL3ENSG00000114686.41438.726102044.07880-0.506704.858903.46930K562UCHL5
MRPL3ENSG00000114686.42621.357403847.68290-0.5537016.7836015.18450K562UPF1
MRPL3ENSG00000114686.42412.017103218.75500-0.416305.244402.94540K562UPF2
MRPL3ENSG00000114686.42358.686303292.35830-0.481106.929405.50370K562WDR3
MRPL3ENSG00000114686.43696.590704877.85920-0.400104.754403.57600K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MRPL3 is not available on ENCORE database.





4 RBPs can affect the splicing of MRPL3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMRPL3ENSG00000114686.4chr3-131220687131220768131220374131220559131221573131221827-0.057000.000850.01790excludedHepG2U2AF1
SEMRPL3ENSG00000114686.4chr3-131217022131217121131208824131208924131219273131219365-0.140000.000000.00000excludedK562SUPV3L1
SEMRPL3ENSG00000114686.4chr3-131220687131220768131220374131220559131221573131221827-0.080000.000440.07741excludedK562SBDS
A3SSMRPL3ENSG00000114686.4chr3-1311885751311886301311885751311886171311900141311901230.054000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MRPL3 is not avaliable on ENCORE database.