MAP3K8

General Information

Gene Name       : MAP3K8
Gene ID             : ENSG00000107968.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MAP3K8)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MAP3K8ENSG00000107968.927.5426.5927.06ENCSR000AEF
HepG2MAP3K8ENSG00000107968.98.3012.0310.16ENCSR985KAT
K562MAP3K8ENSG00000107968.98.338.068.20ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MAP3K8 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MAP3K8 RNA is bound by 5 proteins.  







eCLIP assay for MAP3K8 is not avaliable on ENCORE database.





5 proteins are bound to MAP3K8 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr103072329730723384+5'-UTR,intron-Proximal3.1916510.11479HepG2PRPF8
chr103072330630723313+5'-UTR,intron-Proximal5.511398.34710K562AQR
chr103073944130739498+CDS,intron-Proximal4.603314.65563K562AQR
chr103073944330739513+CDS,intron-Proximal4.692765.33214K562PRPF8
chr103074812230748229+CDS,intron-Proximal3.539793.96535HepG2AQR
chr103074842130748472+CDS,intron-Proximal4.761775.27173HepG2PRPF8
chr103072795330728022+CDS3.145963.55800HepG2BCLAF1
chr103074720930747304+intron-Distal,intron-Proximal4.184883.31283K562PRPF8
chr103072331330723355+intron-Proximal6.0135811.56697K562AQR
chr103072333330723398+intron-Proximal5.538969.52435HepG2RBM22
chr103072333230723392+intron-Proximal3.462483.13705K562BUD13
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MAP3K8 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MAP3K8 is not available on ENCORE database.

  • 88 RBPs can affect the levels of MAP3K8.  








The Knockdown/knockout RNA-Seq assay for MAP3K8 is not available on ENCORE database.





88 RBPs can affect the gene expression of MAP3K8 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MAP3K8ENSG00000107968.5193.47270314.16630-0.699403.979303.27490HepG2ACO1
MAP3K8ENSG00000107968.5109.74490257.54590-1.230707.192506.37940HepG2AKAP1
MAP3K8ENSG00000107968.583.86080184.83980-1.140206.048405.20350HepG2BOP1
MAP3K8ENSG00000107968.5501.93850314.018000.676607.717306.71300HepG2CKAP4
MAP3K8ENSG00000107968.5213.15810369.69910-0.794407.001206.06740HepG2CELF1
MAP3K8ENSG00000107968.5194.79690290.52200-0.576704.173403.17360HepG2DDX19B
MAP3K8ENSG00000107968.5130.87430199.36740-0.607202.693001.55010HepG2DDX1
MAP3K8ENSG00000107968.5355.71120188.326600.917407.183106.14160HepG2DDX21
MAP3K8ENSG00000107968.5168.33760246.71920-0.551502.225001.65820HepG2DDX3X
MAP3K8ENSG00000107968.5116.24870185.56150-0.674702.135101.44760HepG2DDX55
MAP3K8ENSG00000107968.5150.42830259.79520-0.788304.534703.25700HepG2DDX5
MAP3K8ENSG00000107968.5300.87150211.914100.505602.020001.48490HepG2DDX6
MAP3K8ENSG00000107968.5179.55890300.55130-0.743203.847403.07390HepG2DKC1
MAP3K8ENSG00000107968.5136.80180195.49680-0.515102.195901.56190HepG2DNAJC21
MAP3K8ENSG00000107968.5132.42230212.22980-0.680502.754101.83640HepG2EEF2
MAP3K8ENSG00000107968.5106.34520176.91970-0.734303.041701.88240HepG2EFTUD2
MAP3K8ENSG00000107968.5363.23430203.740800.834105.470304.65310HepG2EIF2S1
MAP3K8ENSG00000107968.5106.67290177.92560-0.738103.309902.14190HepG2EIF3G
MAP3K8ENSG00000107968.5454.35190225.168501.012708.364507.25560HepG2EIF4A3
MAP3K8ENSG00000107968.5122.32790219.21220-0.841603.349002.59680HepG2EIF4B
MAP3K8ENSG00000107968.5597.92320392.173800.608406.484105.29780HepG2EIF4G1
MAP3K8ENSG00000107968.5199.60120306.92560-0.620803.714902.74800HepG2EWSR1
MAP3K8ENSG00000107968.5104.86750210.73460-1.006905.341504.43040HepG2G3BP1
MAP3K8ENSG00000107968.5327.59290187.920500.801704.157002.79550HepG2GRSF1
MAP3K8ENSG00000107968.5215.94260299.89030-0.473802.944601.94120HepG2HDGF
MAP3K8ENSG00000107968.5486.70440213.347201.1897012.2130010.84850HepG2HNRNPK
MAP3K8ENSG00000107968.5102.89280218.07730-1.083708.106107.10800HepG2HNRNPU
MAP3K8ENSG00000107968.5337.87550240.791700.488602.718702.00130HepG2IGF2BP1
MAP3K8ENSG00000107968.5147.98390222.76030-0.590103.432002.62190HepG2ILF2
MAP3K8ENSG00000107968.5120.55260197.90360-0.715102.701101.40210HepG2ILF3
MAP3K8ENSG00000107968.5123.91810193.45190-0.642602.500501.38090HepG2KHDRBS1
MAP3K8ENSG00000107968.5176.85720302.49250-0.774303.866702.88220HepG2LARP4
MAP3K8ENSG00000107968.5137.69730216.98610-0.656103.314402.43250HepG2MSI2
MAP3K8ENSG00000107968.5291.62420394.16680-0.434702.633501.88970HepG2NOL12
MAP3K8ENSG00000107968.5408.37750208.319600.971007.809406.61190HepG2PABPC4
MAP3K8ENSG00000107968.5398.23110226.583200.813504.747403.41310HepG2PCBP2
MAP3K8ENSG00000107968.5322.00630173.194900.894605.891403.54430HepG2PHF6
MAP3K8ENSG00000107968.560.46030142.47180-1.236606.282404.47510HepG2PKM
MAP3K8ENSG00000107968.5121.02370194.50910-0.684503.496602.67770HepG2PPIL4
MAP3K8ENSG00000107968.5122.05170238.18960-0.964604.697203.14370HepG2PRPF6
MAP3K8ENSG00000107968.5132.31650376.26980-1.5078016.7375015.44110HepG2PUF60
MAP3K8ENSG00000107968.5165.87900399.43060-1.2678017.7423016.50760HepG2PUM1
MAP3K8ENSG00000107968.5189.71670319.98700-0.754205.859805.02360HepG2PUS1
MAP3K8ENSG00000107968.5419.89510218.640500.941404.860203.94050HepG2RAVER1
MAP3K8ENSG00000107968.5201.10590320.88180-0.674104.350803.73930HepG2RBM22
MAP3K8ENSG00000107968.577.15630167.63990-1.119505.852604.99800HepG2RPS19
MAP3K8ENSG00000107968.5301.68930203.863200.565402.396101.64850HepG2RPS3A
MAP3K8ENSG00000107968.5127.53710194.21270-0.606702.937502.27840HepG2SAFB2
MAP3K8ENSG00000107968.5146.59930319.01380-1.121703.068301.62490HepG2SF1
MAP3K8ENSG00000107968.5118.37190309.44920-1.386403.995902.19440HepG2SFPQ
MAP3K8ENSG00000107968.5122.09370226.49370-0.891506.160805.26030HepG2SMN1
MAP3K8ENSG00000107968.5445.75130188.748701.2397018.3403017.14900HepG2SRSF9
MAP3K8ENSG00000107968.5528.44360329.861700.679804.501202.89710HepG2SSRP1
MAP3K8ENSG00000107968.5103.13450177.34660-0.782003.382202.15250HepG2STIP1
MAP3K8ENSG00000107968.5308.74820422.51230-0.452603.241002.57860HepG2SUCLG1
MAP3K8ENSG00000107968.5268.72170181.034600.569702.675201.74790HepG2SUPT6H
MAP3K8ENSG00000107968.586.65580184.73490-1.092104.532703.69840HepG2SUPV3L1
MAP3K8ENSG00000107968.5312.17440211.936300.558603.357902.81660HepG2TIAL1
MAP3K8ENSG00000107968.5171.41300389.10860-1.182708.264106.78680HepG2UBE2L3
MAP3K8ENSG00000107968.5184.77640109.136300.759503.594702.73200HepG2UCHL5
MAP3K8ENSG00000107968.5226.30220296.43240-0.389502.083401.46290HepG2UPF1
MAP3K8ENSG00000107968.5168.69220286.19400-0.762605.330304.54400HepG2UTP3
MAP3K8ENSG00000107968.572.60560193.33690-1.4130010.603609.43040HepG2ZC3H8
MAP3K8ENSG00000107968.5514.64050344.638400.578405.395604.64480K562AGGF1
MAP3K8ENSG00000107968.5496.86930378.715700.391702.405501.49850K562AKAP8
MAP3K8ENSG00000107968.5496.74990358.614400.470003.093702.40180K562AKAP8L
MAP3K8ENSG00000107968.5473.98110376.277500.332902.130201.33610K562ATP5C1
MAP3K8ENSG00000107968.5297.08710155.070800.937905.964504.67350K562BOP1
MAP3K8ENSG00000107968.5288.65620164.880400.807802.136701.43890K562CPSF6
MAP3K8ENSG00000107968.5277.60220173.273100.679903.454702.43020K562EFTUD2
MAP3K8ENSG00000107968.5398.35400261.713100.606004.728903.82010K562EIF2S2
MAP3K8ENSG00000107968.5273.54660185.488700.560402.312801.37660K562EIF3D
MAP3K8ENSG00000107968.5289.65910181.063800.677803.630002.31200K562FKBP4
MAP3K8ENSG00000107968.5317.15980167.770300.918606.265804.96210K562FMR1
MAP3K8ENSG00000107968.5233.14390142.204100.713203.373002.35600K562FTO
MAP3K8ENSG00000107968.5190.55910253.96280-0.414401.832301.31970K562FXR1
MAP3K8ENSG00000107968.5247.45710157.416700.652503.158602.31200K562GPKOW
MAP3K8ENSG00000107968.5357.27690258.701800.465702.684901.62860K562HNRNPA1
MAP3K8ENSG00000107968.5208.47320286.47750-0.458602.487801.64010K562HNRNPU
MAP3K8ENSG00000107968.5532.87590380.570800.485503.047502.17850K562KIF1C
MAP3K8ENSG00000107968.5221.41850134.423400.719902.795401.85640K562KRR1
MAP3K8ENSG00000107968.5206.21230298.03320-0.531302.847801.99430K562MAGOH
MAP3K8ENSG00000107968.5266.97040153.657700.796904.647603.49120K562METAP2
MAP3K8ENSG00000107968.5317.29220236.508100.423802.321701.57920K562MTPAP
MAP3K8ENSG00000107968.5360.30800504.76000-0.486402.883001.41460K562PNPT1
MAP3K8ENSG00000107968.5204.23250289.55520-0.503602.773702.10840K562PTBP1
MAP3K8ENSG00000107968.5350.26500536.00960-0.613803.600002.67210K562PUF60
MAP3K8ENSG00000107968.5578.35140355.629300.701506.001305.23920K562PUS1
MAP3K8ENSG00000107968.5106.81780170.69940-0.676302.623201.65960K562RCC2
MAP3K8ENSG00000107968.5344.04820241.287100.511802.542301.34750K562STAU1
MAP3K8ENSG00000107968.5195.59920287.29010-0.554602.831102.11610K562TARDBP
MAP3K8ENSG00000107968.5340.18160238.434100.512602.943202.04110K562WDR3
MAP3K8ENSG00000107968.5604.97800434.720600.476703.703702.20170K562WRN
MAP3K8ENSG00000107968.5572.07950413.188100.469303.407302.43420K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MAP3K8 is not available on ENCORE database.





10 RBPs can affect the splicing of MAP3K8 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMAP3K8ENSG00000107968.5chr10+3072610430726335307231723072330730727844307284100.441000.000390.00962includedK562SRSF1
SEMAP3K8ENSG00000107968.5chr10+307261043072633530723172307233073072784430728410-0.335000.000000.00008excludedK562AKAP8L
SEMAP3K8ENSG00000107968.5chr10+3072610430726335307228653072330730727844307284100.491000.000050.00332includedK562FXR1
SEMAP3K8ENSG00000107968.5chr10+307261043072633530723172307233073072784430728410-0.307000.000020.00054excludedK562PUS1
SEMAP3K8ENSG00000107968.5chr10+3072624130726335307230693072330730727844307284100.548000.000300.02568includedK562HNRNPL
SEMAP3K8ENSG00000107968.5chr10+307261043072633530723172307233073072784430728410-0.429000.000440.09249excludedHepG2NOL12
SEMAP3K8ENSG00000107968.5chr10+307261043072633530723172307233073072784430728410-0.293000.001020.03459excludedK562UTP18
SEMAP3K8ENSG00000107968.5chr10+307261043072633530723172307233073072784430728410-0.308000.000070.00333excludedK562RBM15
SEMAP3K8ENSG00000107968.5chr10+307261043072633530723172307233073072784430728410-0.367000.000000.00000excludedK562AGGF1
SEMAP3K8ENSG00000107968.5chr10+307261043072633530723172307233073072784430728410-0.448000.000080.02404excludedK562NPM1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MAP3K8 is not avaliable on ENCORE database.