MAN2B1

General Information

Gene Name       : MAN2B1
Gene ID             : ENSG00000104774.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MAN2B1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MAN2B1ENSG00000104774.1218.6541.1029.88ENCSR000AEF
HepG2MAN2B1ENSG00000104774.1242.8918.9430.91ENCSR985KAT
K562MAN2B1ENSG00000104774.1212.987.6610.32ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MAN2B1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MAN2B1 RNA is bound by 12 proteins.  







eCLIP assay for MAN2B1 is not avaliable on ENCORE database.





12 proteins are bound to MAN2B1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr191275735512757467-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.740457.71063HepG2LARP4
chr191276317512763250-3'-UTR,CDS,intron-Distal,intron-Proximal4.811598.30668K562YBX3
chr191277741512777525-5'-UTR,CDS,intron-Distal,intron-Proximal3.4647911.13092HepG2DDX3X
chr191276652712766606-CDS,intron-Distal4.318703.67707K562METAP2
chr191275902612759075-CDS,intron-Distal5.153663.48040HepG2SND1
chr191276903612769046-CDS,intron-Distal,intron-Proximal5.407919.31998HepG2LIN28B
chr191277660312776619-CDS,intron-Distal3.173663.08258K562TIA1
chr191276909912769146-CDS,intron-Distal,intron-Proximal3.100293.86052K562YBX3
chr191275998112760025-CDS,intron-Distal4.026213.33639K562METAP2
chr191276095612761005-CDS,intron-Distal4.3743611.40770K562YBX3
chr191276889812768957-CDS,intron-Distal,intron-Proximal6.1548522.29028K562LIN28B
chr191276914612769159-CDS,intron-Distal,intron-Proximal4.156824.55095K562YBX3
chr191276903712769047-CDS,intron-Distal,intron-Proximal4.862378.55117K562LIN28B
chr191276737612767456-CDS,intron-Distal,intron-Proximal3.173683.22545HepG2PPIG
chr191276890212768956-CDS,intron-Distal,intron-Proximal4.8304722.57080HepG2LIN28B
chr191277201612772086-CDS,intron-Distal,intron-Proximal4.704034.68690HepG2PRPF8
chr191276923912769286-CDS,intron-Distal,intron-Proximal4.737856.92025K562YBX3
chr191275808412758148-CDS,intron-Distal3.558763.84718K562METAP2
chr191277616712776261-CDS,intron-Distal3.435287.24294K562YBX3
chr191276688812766997-intron-Distal4.932155.68967HepG2PCBP2
chr191276733912767374-intron-Distal,intron-Proximal5.251803.62536K562AQR
chr191276737412767384-intron-Distal,intron-Proximal4.942343.11721K562AQR
chr191276686912767024-intron-Distal4.259354.76505K562HNRNPK
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MAN2B1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MAN2B1 is not available on ENCORE database.

  • 95 RBPs can affect the levels of MAN2B1.  








The Knockdown/knockout RNA-Seq assay for MAN2B1 is not available on ENCORE database.





95 RBPs can affect the gene expression of MAN2B1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MAN2B1ENSG00000104774.82043.466301579.124300.371802.386401.51100HepG2ABCF1
MAN2B1ENSG00000104774.81531.450501267.370200.273003.373502.71240HepG2ACO1
MAN2B1ENSG00000104774.82580.038501649.614500.645203.865603.25260HepG2AKAP1
MAN2B1ENSG00000104774.82012.277801448.963700.473703.845102.62190HepG2AKAP8
MAN2B1ENSG00000104774.81799.666501273.228800.499109.213007.91680HepG2AKAP8L
MAN2B1ENSG00000104774.81042.424001266.97950-0.281503.399302.67610HepG2CKAP4
MAN2B1ENSG00000104774.81832.514701174.693500.641402.295101.70050HepG2CELF1
MAN2B1ENSG00000104774.81110.05990828.799900.421402.992601.79240HepG2DDX1
MAN2B1ENSG00000104774.81255.55860901.764100.477404.716203.85670HepG2DDX21
MAN2B1ENSG00000104774.82374.002201579.894100.587403.882903.15250HepG2DDX3X
MAN2B1ENSG00000104774.82719.934801357.895801.0021010.114609.01360HepG2DDX6
MAN2B1ENSG00000104774.81068.15200805.596400.406904.606303.80030HepG2DNAJC2
MAN2B1ENSG00000104774.81958.832101304.649600.586203.590102.91880HepG2EIF2S1
MAN2B1ENSG00000104774.81521.233101197.574100.345002.919901.71700HepG2EIF2S2
MAN2B1ENSG00000104774.8836.377101404.11560-0.747402.401201.75920HepG2EIF4B
MAN2B1ENSG00000104774.8836.416501238.34480-0.566106.847705.53750HepG2EWSR1
MAN2B1ENSG00000104774.81018.16700775.432000.392803.302002.01060HepG2FAM120A
MAN2B1ENSG00000104774.81832.774301349.552400.441401.909201.35160HepG2G3BP1
MAN2B1ENSG00000104774.81130.66710772.233700.550004.807203.62690HepG2GEMIN5
MAN2B1ENSG00000104774.81517.039801173.350600.370502.421601.81870HepG2GPKOW
MAN2B1ENSG00000104774.81568.28230980.873500.676905.036603.53210HepG2GRSF1
MAN2B1ENSG00000104774.81095.92630820.449000.417602.810302.15870HepG2HNRNPA1
MAN2B1ENSG00000104774.8638.83510912.63440-0.514603.908703.09540HepG2HNRNPC
MAN2B1ENSG00000104774.82171.894801367.853800.666904.607203.72460HepG2HNRNPK
MAN2B1ENSG00000104774.81912.902601150.210500.7338011.6608010.36180HepG2HNRNPL
MAN2B1ENSG00000104774.81429.266401119.756300.352002.455901.85760HepG2HNRNPLL
MAN2B1ENSG00000104774.81208.34640906.597900.414403.162902.51850HepG2HNRNPU
MAN2B1ENSG00000104774.81411.29550926.053500.607809.724008.43160HepG2ILF2
MAN2B1ENSG00000104774.81348.044901158.463600.218602.371601.42690HepG2KIF1C
MAN2B1ENSG00000104774.8922.647801455.93060-0.658102.298801.69920HepG2MAGOH
MAN2B1ENSG00000104774.82073.152101290.040800.6843010.434508.96670HepG2MSI2
MAN2B1ENSG00000104774.82049.777801498.248000.452102.285301.70760HepG2NCBP2
MAN2B1ENSG00000104774.81773.390501252.191600.502005.112004.08020HepG2NOL12
MAN2B1ENSG00000104774.81265.70930897.330900.496107.599206.30670HepG2PARN
MAN2B1ENSG00000104774.8851.116801490.32130-0.8082019.8361018.45100HepG2PCBP1
MAN2B1ENSG00000104774.81266.87690808.606500.647703.186102.40010HepG2PPIL4
MAN2B1ENSG00000104774.8499.49540670.27680-0.424301.991401.30140HepG2PRPF8
MAN2B1ENSG00000104774.81676.645801195.409100.488006.090205.25100HepG2PUF60
MAN2B1ENSG00000104774.81663.686501269.076400.390506.062905.25510HepG2PUM1
MAN2B1ENSG00000104774.81977.743701599.923200.305803.170502.25900HepG2RBM15
MAN2B1ENSG00000104774.81084.682201593.02920-0.554506.643505.92360HepG2RBM22
MAN2B1ENSG00000104774.8976.615901490.54540-0.610008.229507.11570HepG2RBM25
MAN2B1ENSG00000104774.81388.57520844.093000.7180010.262109.16700HepG2RPS19
MAN2B1ENSG00000104774.81248.90870807.344000.6293012.8770011.63910HepG2SAFB2
MAN2B1ENSG00000104774.82026.033101502.002900.431702.782002.10630HepG2SF3A3
MAN2B1ENSG00000104774.8772.308501108.29770-0.521104.894603.97840HepG2SF3B1
MAN2B1ENSG00000104774.81112.348401578.81350-0.505208.596707.64360HepG2SF3B4
MAN2B1ENSG00000104774.81483.62600748.552800.986902.860901.38300HepG2SFPQ
MAN2B1ENSG00000104774.81668.786801146.409800.541609.029407.87630HepG2SLBP
MAN2B1ENSG00000104774.81302.15560941.463100.467808.501007.47190HepG2SMN1
MAN2B1ENSG00000104774.81374.50680839.811100.710704.229703.02730HepG2SMNDC1
MAN2B1ENSG00000104774.81256.44730689.512700.865602.628001.36290HepG2SNRNP200
MAN2B1ENSG00000104774.8922.902601799.21030-0.9631015.0092014.08960HepG2SRFBP1
MAN2B1ENSG00000104774.8723.724301647.95370-1.1872040.4569039.11250HepG2SRSF1
MAN2B1ENSG00000104774.8817.237201192.64530-0.545303.739302.55620HepG2SRSF3
MAN2B1ENSG00000104774.82061.106201180.408400.8040024.8394023.23540HepG2SRSF5
MAN2B1ENSG00000104774.8869.651501340.71050-0.6245012.6226011.59510HepG2SRSF9
MAN2B1ENSG00000104774.81211.593901562.04010-0.366504.348003.73520HepG2SSB
MAN2B1ENSG00000104774.81865.562401342.350300.474708.166707.19390HepG2SUCLG1
MAN2B1ENSG00000104774.81332.105001076.303700.307502.336001.46660HepG2SUPT6H
MAN2B1ENSG00000104774.81208.59670865.427600.481702.110401.50930HepG2SUPV3L1
MAN2B1ENSG00000104774.81010.979301481.28480-0.551103.642703.01420HepG2TAF15
MAN2B1ENSG00000104774.82286.070501091.598401.0663021.6154019.95310HepG2TARDBP
MAN2B1ENSG00000104774.81295.74790880.792000.556807.090406.35740HepG2TIAL1
MAN2B1ENSG00000104774.81633.99550888.813000.8784025.2699023.77930HepG2TRIM56
MAN2B1ENSG00000104774.81479.620001168.022200.341103.485702.49330HepG2TUFM
MAN2B1ENSG00000104774.8834.355201363.71730-0.708808.888707.75650HepG2U2AF1
MAN2B1ENSG00000104774.81677.833201332.047900.332904.913704.02550HepG2UPF1
MAN2B1ENSG00000104774.83961.485601464.996301.43500118.69390116.54880HepG2ZNF622
MAN2B1ENSG00000104774.8351.07040559.48540-0.672305.701203.93800K562AARS
MAN2B1ENSG00000104774.8871.38720647.008000.429403.064801.76930K562ABCF1
MAN2B1ENSG00000104774.81385.370501071.652800.370304.811304.09750K562AGGF1
MAN2B1ENSG00000104774.81550.619001177.592400.396903.744002.56230K562AKAP8
MAN2B1ENSG00000104774.81623.013801115.105300.541402.957802.28210K562AKAP8L
MAN2B1ENSG00000104774.81520.247001170.017600.377704.584703.37490K562ATP5C1
MAN2B1ENSG00000104774.8680.69510444.243500.615604.844603.67760K562BOP1
MAN2B1ENSG00000104774.8677.24050419.501500.690905.227003.67560K562CCAR1
MAN2B1ENSG00000104774.8709.77960432.636300.714107.192005.21620K562CIRBP
MAN2B1ENSG00000104774.8466.94640330.108000.500203.578202.35330K562CSTF2
MAN2B1ENSG00000104774.8849.28120562.297500.594806.626704.92630K562DDX3X
MAN2B1ENSG00000104774.8653.97170854.67540-0.386102.638302.00030K562DDX47
MAN2B1ENSG00000104774.81054.17950557.731300.9184018.0730016.46900K562EIF2S2
MAN2B1ENSG00000104774.8597.47440465.078200.361302.120801.37470K562FIP1L1
MAN2B1ENSG00000104774.8436.48030610.95650-0.485204.239703.51360K562FXR1
MAN2B1ENSG00000104774.8100.64990245.45470-1.286104.351603.42090K562G3BP2
MAN2B1ENSG00000104774.8759.21450450.914200.751607.987806.63470K562GPKOW
MAN2B1ENSG00000104774.81150.55660743.144900.630507.099205.87920K562GRSF1
MAN2B1ENSG00000104774.8360.56290611.92360-0.763107.600906.65770K562HNRNPC
MAN2B1ENSG00000104774.81067.96070772.457100.467204.618603.21800K562HNRNPL
MAN2B1ENSG00000104774.8974.87670630.557500.628506.188605.01020K562HSPD1
MAN2B1ENSG00000104774.8787.50640403.863000.963304.871703.34630K562IGF2BP2
MAN2B1ENSG00000104774.8558.78740410.702900.444103.110701.83050K562IGF2BP3
MAN2B1ENSG00000104774.8410.37180592.91800-0.530904.153202.39820K562LARP7
MAN2B1ENSG00000104774.8253.29210377.43680-0.575403.423902.33660K562PCBP2
MAN2B1ENSG00000104774.8495.25930651.23650-0.395003.048502.20640K562POLR2G
MAN2B1ENSG00000104774.8677.69600527.945300.360102.150901.43230K562PPIG
MAN2B1ENSG00000104774.8204.07800387.29810-0.924302.159101.49290K562PRPF8
MAN2B1ENSG00000104774.81698.607801105.864700.619107.758106.89560K562PUS1
MAN2B1ENSG00000104774.81342.209101077.510000.316803.135602.51020K562RBM15
MAN2B1ENSG00000104774.8531.82190385.267100.465002.846101.44760K562RBM34
MAN2B1ENSG00000104774.8174.74180404.11150-1.2095013.0553011.51950K562SRSF1
MAN2B1ENSG00000104774.8711.62750513.217700.471502.905101.81710K562SRSF4
MAN2B1ENSG00000104774.8618.93260381.708100.697206.505304.78400K562SRSF5
MAN2B1ENSG00000104774.8584.23870408.939100.514603.505702.70550K562TARDBP
MAN2B1ENSG00000104774.8659.40280394.480500.741107.563206.10710K562TIA1
MAN2B1ENSG00000104774.8621.26910387.216700.682004.405902.97220K562TRA2A
MAN2B1ENSG00000104774.8731.75050560.815000.383702.632301.71510K562TRIM56
MAN2B1ENSG00000104774.8141.68380245.46250-0.792802.725901.92700K562U2AF2
MAN2B1ENSG00000104774.81373.22130977.067300.490908.251807.09280K562UPF1
MAN2B1ENSG00000104774.8704.27890869.38880-0.303902.983302.10440K562WDR43
MAN2B1ENSG00000104774.81021.76890809.807000.335302.564801.74000K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MAN2B1 is not available on ENCORE database.





14 RBPs can affect the splicing of MAN2B1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMAN2B1ENSG00000104774.8chr19-127692411276932112769037127691581277207312772190-0.123000.005860.08561excludedHepG2U2AF1
SEMAN2B1ENSG00000104774.8chr19-127601541276024212759949127600301276072612760828-0.097000.001640.01849excludedK562AQR
SEMAN2B1ENSG00000104774.8chr19-127692411276932412769037127691581277207312772210-0.104000.005310.04885excludedK562AQR
SEMAN2B1ENSG00000104774.8chr19-127601541276024212759949127600301276072612760828-0.069000.000030.00264excludedHepG2PCBP1
SEMAN2B1ENSG00000104774.8chr19-127601541276024212759949127600301276072612760828-0.124000.000260.00617excludedK562HNRNPC
SEMAN2B1ENSG00000104774.8chr19-127692411276932412769037127691581277207312772190-0.244000.000000.00000excludedK562HNRNPC
A3SSMAN2B1ENSG00000104774.8chr19-1277207312772226127720731277219012774130127742760.062000.018130.08768longerK562AQR
RIMAN2B1ENSG00000104774.8chr19-1276650712767501127665071276669312767384127675010.247000.002770.05329includedK562SRSF1
RIMAN2B1ENSG00000104774.8chr19-1276650712767501127665071276669312767384127675010.099000.000060.00366includedHepG2MATR3
RIMAN2B1ENSG00000104774.8chr19-1276650712767501127665071276669312767384127675010.061000.007720.07735includedHepG2PCBP1
RIMAN2B1ENSG00000104774.8chr19-1276650712767501127665071276669312767384127675010.139000.000000.00008includedHepG2TAF15
RIMAN2B1ENSG00000104774.8chr19-1276650712767501127665071276669312767384127675010.266000.000000.00000includedHepG2U2AF1
RIMAN2B1ENSG00000104774.8chr19-1276650712767501127665071276669312767384127675010.061000.001770.02256includedHepG2NCBP2
RIMAN2B1ENSG00000104774.8chr19-1276650712767501127665071276669312767384127675010.072000.002800.02194includedHepG2SF3B4
RIMAN2B1ENSG00000104774.8chr19-1276650712767501127665071276669312767384127675010.073000.003020.05954includedHepG2PTBP1
MXEMAN2B1ENSG00000104774.8chr19-1275994912760030127601541276024212758988127592161276072612760828-0.134000.007370.094962includedHepG2U2AF1
MXEMAN2B1ENSG00000104774.8chr19-1275994912760030127601541276024212758988127592161276072612760828-0.239000.000170.008822includedK562UCHL5
MXEMAN2B1ENSG00000104774.8chr19-1275994912760030127601541276024212758988127592161276072612760828-0.203000.001490.044462includedK562XRN2
MXEMAN2B1ENSG00000104774.8chr19-1275994912760030127607261276082812758988127592161276091712761036-0.233000.002670.041172includedK562SRSF1
MXEMAN2B1ENSG00000104774.8chr19-1275994912760030127601541276024212758988127592161276072612760828-0.114000.009440.075892includedHepG2SFPQ
MXEMAN2B1ENSG00000104774.8chr19-1275994912760030127601541276024212758988127592161276072612760828-0.230000.000330.065442includedK562GEMIN5

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MAN2B1 is not avaliable on ENCORE database.