LTA4H

General Information

Gene Name       : LTA4H
Gene ID             : ENSG00000111144.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: LTA4H)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LTA4HENSG00000111144.962.8050.0756.44ENCSR000AEF
HepG2LTA4HENSG00000111144.955.2981.0768.18ENCSR985KAT
K562LTA4HENSG00000111144.933.1239.0736.09ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LTA4H is not avaliable on ENCORE database.



Proteins bound to RNA
  • LTA4H RNA is bound by 6 proteins.  







eCLIP assay for LTA4H is not avaliable on ENCORE database.





6 proteins are bound to LTA4H RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr129639483996394885-3'-UTR,CDS,intron-Distal3.349474.91258K562YBX3
chr129641087496410893-3'-UTR,CDS,intron-Distal,intron-Proximal3.745253.06406HepG2IGF2BP1
chr129641133396411360-3'-UTR,CDS,intron-Distal,intron-Proximal3.143163.07497K562SND1
chr129639461196394671-3'-UTR,intron-Distal,intron-Proximal5.808727.71888HepG2SUB1
chr129641133196411360-3'-UTR,CDS,intron-Distal,intron-Proximal4.222354.33846HepG2IGF2BP1
chr129639673796396772-3'-UTR,CDS,intron-Distal,intron-Proximal4.180534.72754K562YBX3
chr129641133196411360-3'-UTR,CDS,intron-Distal,intron-Proximal3.546703.08588HepG2IGF2BP3
chr129641084196410893-3'-UTR,CDS,intron-Distal,intron-Proximal4.210453.60906K562SND1
chr129641253996412624-3'-UTR,CDS,intron-Distal,intron-Proximal4.095474.33846HepG2IGF2BP1
chr129641599496416030-5'-UTR,CDS,intron-Distal,intron-Proximal3.677816.42513K562YBX3
chr129641825596418277-5'-UTR,CDS,intron-Distal,intron-Proximal3.430563.28366HepG2BCLAF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LTA4H is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LTA4H is not available on ENCORE database.

  • 106 RBPs can affect the levels of LTA4H.  








The Knockdown/knockout RNA-Seq assay for LTA4H is not available on ENCORE database.





106 RBPs can affect the gene expression of LTA4H :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LTA4HENSG00000111144.51719.338002220.99750-0.369406.797905.93070HepG2ACO1
LTA4HENSG00000111144.53265.818005299.00930-0.698308.077907.22040HepG2AKAP1
LTA4HENSG00000111144.52174.734702967.16790-0.448203.674602.48370HepG2AKAP8
LTA4HENSG00000111144.51777.252402231.42030-0.328304.885503.89100HepG2AKAP8L
LTA4HENSG00000111144.52872.620204384.54770-0.610107.492006.22850HepG2ASCC1
LTA4HENSG00000111144.51323.033102011.73340-0.604607.871706.92590HepG2BOP1
LTA4HENSG00000111144.53051.638304165.60200-0.448904.524303.54870HepG2CIRBP
LTA4HENSG00000111144.51743.552702999.75370-0.782806.242705.09430HepG2CNOT7
LTA4HENSG00000111144.52177.103802779.56820-0.352505.444804.59850HepG2CELF1
LTA4HENSG00000111144.52650.405602054.097800.367607.624106.35520HepG2DDX19B
LTA4HENSG00000111144.51668.190902172.05710-0.380803.759202.97970HepG2DDX21
LTA4HENSG00000111144.52662.209402125.610600.324603.371002.35710HepG2DDX24
LTA4HENSG00000111144.52562.554405076.18410-0.9862017.7313016.29290HepG2DDX3X
LTA4HENSG00000111144.51390.369004360.23150-1.6489038.6511036.73990HepG2DDX6
LTA4HENSG00000111144.51810.883202124.88900-0.230702.585701.92820HepG2DKC1
LTA4HENSG00000111144.51554.938601998.79010-0.362304.396303.60810HepG2DNAJC2
LTA4HENSG00000111144.51373.937402302.94860-0.7452010.127408.50460HepG2EEF2
LTA4HENSG00000111144.52312.719704191.90960-0.8580013.6594012.41000HepG2EIF2S1
LTA4HENSG00000111144.51476.181001869.50340-0.340802.316701.48280HepG2EIF3D
LTA4HENSG00000111144.51792.572704632.70440-1.3698027.5753025.59510HepG2EIF4A3
LTA4HENSG00000111144.51812.559404510.29860-1.3152020.2441018.50260HepG2EIF4B
LTA4HENSG00000111144.53816.181602824.532700.434004.660703.62060HepG2EIF4G2
LTA4HENSG00000111144.52991.701202354.161600.345703.252302.07170HepG2ESF1
LTA4HENSG00000111144.52343.138403962.12560-0.7578027.6488026.08170HepG2ETF1
LTA4HENSG00000111144.51821.966502170.29850-0.252402.061001.34180HepG2EWSR1
LTA4HENSG00000111144.52401.421404673.74610-0.9607017.4052015.83440HepG2FXR1
LTA4HENSG00000111144.52028.031904335.82600-1.0962019.7420018.04190HepG2G3BP1
LTA4HENSG00000111144.53670.528504602.72000-0.326502.649601.77950HepG2G3BP2
LTA4HENSG00000111144.51443.825802151.59220-0.575505.730004.25120HepG2GNB2L1
LTA4HENSG00000111144.51061.665002093.53660-0.9796014.2447012.90080HepG2GPKOW
LTA4HENSG00000111144.51113.209602035.68090-0.8708015.8917014.54990HepG2HNRNPA1
LTA4HENSG00000111144.51427.784602264.39640-0.665309.844508.60350HepG2HNRNPC
LTA4HENSG00000111144.52411.254602722.52330-0.175202.461501.82190HepG2HNRNPL
LTA4HENSG00000111144.51515.827701997.90350-0.398403.365402.67840HepG2HNRNPLL
LTA4HENSG00000111144.52733.040202249.419800.280903.070802.43500HepG2HNRNPU
LTA4HENSG00000111144.51827.445302202.53430-0.269302.327501.66150HepG2IGF2BP1
LTA4HENSG00000111144.51924.282704407.35820-1.1956025.9687024.15510HepG2IGF2BP2
LTA4HENSG00000111144.52238.261404135.76980-0.885804.416103.18050HepG2IGF2BP3
LTA4HENSG00000111144.53290.517104432.88870-0.429902.985601.93780HepG2KHSRP
LTA4HENSG00000111144.52537.679203526.15270-0.474603.534002.59440HepG2LARP4
LTA4HENSG00000111144.51466.838504675.37570-1.6724046.3233043.91790HepG2MAGOH
LTA4HENSG00000111144.51593.051004701.61780-1.5614036.3948034.31910HepG2MATR3
LTA4HENSG00000111144.51852.656902221.02740-0.261602.062401.35890HepG2MSI2
LTA4HENSG00000111144.51544.915404812.42790-1.6392042.7879040.52270HepG2NCBP2
LTA4HENSG00000111144.52459.300002963.62980-0.269102.971702.18200HepG2NOL12
LTA4HENSG00000111144.51974.562702741.59490-0.473502.341101.53690HepG2PABPC1
LTA4HENSG00000111144.51873.501504286.05940-1.1939024.2620022.17770HepG2PABPC4
LTA4HENSG00000111144.52269.216004320.08610-0.9289041.0874039.24680HepG2PCBP1
LTA4HENSG00000111144.53305.266802400.277000.4615010.070308.72910HepG2PRPF4
LTA4HENSG00000111144.51766.490904396.04890-1.3153064.4310062.60570HepG2PTBP1
LTA4HENSG00000111144.51737.945002829.03710-0.7029012.3920011.25040HepG2PUF60
LTA4HENSG00000111144.52278.851703003.13970-0.3982010.167109.18010HepG2PUM1
LTA4HENSG00000111144.52088.438003000.95110-0.523008.897607.72880HepG2PUM2
LTA4HENSG00000111144.51483.216902262.22790-0.6090016.5709015.28890HepG2PUS1
LTA4HENSG00000111144.52552.721304760.60390-0.8991028.8286027.13780HepG2QKI
LTA4HENSG00000111144.51508.953402384.45450-0.660103.995603.15410HepG2RAVER1
LTA4HENSG00000111144.53737.042803027.347800.303703.744302.76330HepG2RBM15
LTA4HENSG00000111144.52709.437704320.71480-0.6733013.0516011.64930HepG2RBM25
LTA4HENSG00000111144.52268.972504892.21440-1.1084054.0273052.35460HepG2NELFE
LTA4HENSG00000111144.53426.671804556.73380-0.411209.260908.23310HepG2RECQL
LTA4HENSG00000111144.51602.666202409.25640-0.588107.772906.71890HepG2RPLP0
LTA4HENSG00000111144.51685.746302341.65350-0.474102.768101.82430HepG2RPS10
LTA4HENSG00000111144.51209.892201819.09450-0.588308.285107.28810HepG2RPS19
LTA4HENSG00000111144.51214.440702344.01610-0.9487016.3702014.54030HepG2RPS2
LTA4HENSG00000111144.51804.098103011.65400-0.739307.068005.80070HepG2RPS3A
LTA4HENSG00000111144.51778.703302392.65910-0.427803.780202.51370HepG2RPS5
LTA4HENSG00000111144.52558.434002003.162000.352906.914505.96360HepG2SAFB2
LTA4HENSG00000111144.51423.477801825.76790-0.359102.747701.81240HepG2SERBP1
LTA4HENSG00000111144.51831.246002791.65050-0.608304.597803.71730HepG2SF3A3
LTA4HENSG00000111144.52334.545304576.49620-0.9711044.5412042.71920HepG2SF3B4
LTA4HENSG00000111144.51576.376302335.94810-0.567409.753108.66260HepG2SMN1
LTA4HENSG00000111144.54332.063603740.320100.211803.390502.85350HepG2SRFBP1
LTA4HENSG00000111144.52124.528104777.01740-1.1690059.9637058.40640HepG2SRSF1
LTA4HENSG00000111144.52063.186402793.25230-0.437108.848907.81200HepG2SRSF5
LTA4HENSG00000111144.51832.471302197.43970-0.262002.995202.27550HepG2SRSF7
LTA4HENSG00000111144.52207.251503886.48400-0.8162033.8104032.29500HepG2SRSF9
LTA4HENSG00000111144.51972.413003247.46780-0.7194024.9207023.72440HepG2SSB
LTA4HENSG00000111144.52681.861503176.70580-0.244303.998303.27490HepG2SUCLG1
LTA4HENSG00000111144.51247.741101754.58380-0.491804.052903.25810HepG2SUPV3L1
LTA4HENSG00000111144.53192.744603945.33160-0.305303.232902.33330HepG2TIA1
LTA4HENSG00000111144.51053.031602185.43990-1.0534026.1426024.89930HepG2TIAL1
LTA4HENSG00000111144.52063.120702763.83620-0.421805.323604.06890HepG2TUFM
LTA4HENSG00000111144.51616.941002475.77000-0.6146017.2408015.78890HepG2UPF1
LTA4HENSG00000111144.51193.435001606.55990-0.428902.329301.41440HepG2UPF2
LTA4HENSG00000111144.52084.200002390.25430-0.197702.205301.65720HepG2UTP3
LTA4HENSG00000111144.51991.288202368.76630-0.250403.806203.04050HepG2ZC3H8
LTA4HENSG00000111144.51203.667402722.86910-1.1777069.0098067.23690HepG2ZNF622
LTA4HENSG00000111144.5864.886401120.34900-0.373403.042801.79810K562AARS
LTA4HENSG00000111144.52567.792101706.569700.5893014.9703013.75960K562AGGF1
LTA4HENSG00000111144.52461.901501775.770400.471205.649004.69660K562AKAP8L
LTA4HENSG00000111144.51128.113901744.55250-0.628907.523906.63340K562AQR
LTA4HENSG00000111144.52560.739601863.224300.458707.767906.11730K562ATP5C1
LTA4HENSG00000111144.51466.174501777.61020-0.277903.159202.46960K562DDX47
LTA4HENSG00000111144.52239.710701910.810700.229002.496301.66960K562DKC1
LTA4HENSG00000111144.5642.61470924.61650-0.524903.311201.90290K562EEF2
LTA4HENSG00000111144.5454.48170680.27530-0.581902.773901.76870K562EIF3A
LTA4HENSG00000111144.5696.69010956.52780-0.457302.881601.82520K562EIF3D
LTA4HENSG00000111144.5724.742701070.58590-0.562907.250205.97220K562EIF3G
LTA4HENSG00000111144.5775.446201205.86840-0.637007.558806.20420K562EIF4A3
LTA4HENSG00000111144.52007.280102327.43950-0.213502.413101.53190K562EIF4G2
LTA4HENSG00000111144.5781.926701254.05560-0.6815011.9095010.74490K562FXR1
LTA4HENSG00000111144.51865.353501365.998400.449402.436501.77980K562G3BP2
LTA4HENSG00000111144.5657.50950974.29120-0.567305.620804.49310K562GPKOW
LTA4HENSG00000111144.5888.438701225.64720-0.464204.659103.90390K562HNRNPC
LTA4HENSG00000111144.52866.539101884.510900.605006.420105.04270K562KIF1C
LTA4HENSG00000111144.51038.584901428.99060-0.460404.001602.98490K562MAGOH
LTA4HENSG00000111144.5984.296501426.19320-0.535004.911003.64080K562MATR3
LTA4HENSG00000111144.52982.342202111.131700.498306.354704.86910K562MBNL1
LTA4HENSG00000111144.52361.824401479.752700.674406.218804.69650K562NAA15
LTA4HENSG00000111144.5926.732001388.30390-0.583105.469304.56300K562PTBP1
LTA4HENSG00000111144.51870.651202539.36260-0.440905.355404.22390K562PUF60
LTA4HENSG00000111144.53039.601401761.025300.7874012.9638011.83520K562PUS1
LTA4HENSG00000111144.52660.809901715.896700.6328013.5682012.25010K562RBM15
LTA4HENSG00000111144.5987.170501331.58260-0.431802.906302.04110K562RBM22
LTA4HENSG00000111144.51041.236501401.19240-0.428402.666401.59520K562NELFE
LTA4HENSG00000111144.5866.382601578.73840-0.865704.671503.32600K562RPS3
LTA4HENSG00000111144.51194.347201573.88280-0.398106.559105.18820K562SRPK2
LTA4HENSG00000111144.5863.604201360.92570-0.656106.443205.37560K562SRSF1
LTA4HENSG00000111144.52008.873101517.157300.404903.586502.01630K562SSRP1
LTA4HENSG00000111144.51016.705901377.50720-0.438203.710002.88550K562TARDBP
LTA4HENSG00000111144.5791.945401056.98940-0.416502.912401.95070K562TIAL1
LTA4HENSG00000111144.51759.158901324.237000.409602.976001.83580K562U2AF1
LTA4HENSG00000111144.51621.961001367.602500.246002.057801.36580K562U2AF2
LTA4HENSG00000111144.52672.818801785.548400.581902.608901.36680K562UTP18
LTA4HENSG00000111144.51032.867501468.83220-0.508009.784808.29980K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LTA4H is not available on ENCORE database.





20 RBPs can affect the splicing of LTA4H :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELTA4HENSG00000111144.5chr12-9639761596397698963967379639684296400091964001870.077000.001120.08304includedHepG2G3BP1
SELTA4HENSG00000111144.5chr12-963976159639769896396667963968429640009196400187-0.230000.000100.00613excludedK562PRPF8
SELTA4HENSG00000111144.5chr12-963976159639769896396737963968429640009196400187-0.148000.000000.00009excludedHepG2U2AF1
SELTA4HENSG00000111144.5chr12-9639761596397698963967379639684296400091964001870.095000.000000.00034includedHepG2ILF3
SELTA4HENSG00000111144.5chr12-963976159639769896396737963968429640009196400187-0.145000.000000.00000excludedHepG2DDX59
SELTA4HENSG00000111144.5chr12-963976159639769896396737963968429640009196400187-0.223000.000000.00000excludedHepG2U2AF2
SELTA4HENSG00000111144.5chr12-964075279640770896402871964070369640863296408856-0.073000.002410.02559excludedK562AQR
SELTA4HENSG00000111144.5chr12-9640553096405643964028719640292696406965964070360.111000.000090.01065includedHepG2FTO
SELTA4HENSG00000111144.5chr12-963976159639769896396737963968429640009196400187-0.162000.000880.04678excludedK562EFTUD2
SELTA4HENSG00000111144.5chr12-9639761596397698963967379639684296400091964001870.241000.000000.00119includedK562ILF3
SELTA4HENSG00000111144.5chr12-9639761596397698963967379639684296400091964001870.095000.000040.00326includedHepG2MATR3
SELTA4HENSG00000111144.5chr12-963976159639769896396737963968429640009196400187-0.212000.000000.00002excludedK562U2AF1
SELTA4HENSG00000111144.5chr12-963976159639769896396737963968429640009196400187-0.173000.000000.00000excludedHepG2HNRNPL
SELTA4HENSG00000111144.5chr12-9639761596397698963967379639684296400091964001870.079000.000470.03842includedHepG2IGF2BP3
SELTA4HENSG00000111144.5chr12-963976159639769896396737963968429640009196400187-0.146000.000040.00525excludedHepG2TIAL1
SELTA4HENSG00000111144.5chr12-963976159639775996396767963968429640009196400187-0.081000.001000.09200excludedHepG2RBFOX2
SELTA4HENSG00000111144.5chr12-9639761596397698963967379639684296400091964001870.087000.000000.00039includedHepG2SF3B4
SELTA4HENSG00000111144.5chr12-9639761596397698963967379639684296400091964001870.131000.000020.00644includedK562UPF1
SELTA4HENSG00000111144.5chr12-963976159639769896396737963968429640009196400187-0.434000.000000.00000excludedK562U2AF2
SELTA4HENSG00000111144.5chr12-963976159639769896396737963968429640009196400187-0.265000.000000.00000excludedK562TARDBP
SELTA4HENSG00000111144.5chr12-963976159639769896396737963968429640009196400187-0.246000.000000.00000excludedHepG2HNRNPC
SELTA4HENSG00000111144.5chr12-963976159639769896396737963968429640009196400187-0.121000.000070.02463excludedHepG2FUS
SELTA4HENSG00000111144.5chr12-9639761596397698963967379639684296400091964001870.108000.000250.05049includedK562NPM1
SELTA4HENSG00000111144.5chr12-963976159639769896396667963968429640009196400187-0.350000.000000.00000excludedK562HNRNPC
A3SSLTA4HENSG00000111144.5chr12-9641294596413034964129459641301896414862964149460.077000.000020.00024longerK562AQR
A3SSLTA4HENSG00000111144.5chr12-9639761596397790963976159639769896400091964001870.082000.000000.00001longerK562AQR
RILTA4HENSG00000111144.5chr12-9640287196407036964028719640292696406965964070360.087000.000000.00000includedHepG2MATR3
MXELTA4HENSG00000111144.5chr12-96412945964130349641592496416052964125409641268196418256964183250.068000.000330.003461includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LTA4H is not avaliable on ENCORE database.