LIMS1

General Information

Gene Name       : LIMS1
Gene ID             : ENSG00000169756.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: LIMS1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LIMS1ENSG00000169756.1631.0732.1831.62ENCSR000AEF
HepG2LIMS1ENSG00000169756.1639.4943.5141.50ENCSR985KAT
K562LIMS1ENSG00000169756.1663.1066.2464.67ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LIMS1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • LIMS1 RNA is bound by 29 proteins.  







eCLIP assay for LIMS1 is not avaliable on ENCORE database.





29 proteins are bound to LIMS1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2109303558109303647+3'-UTR3.749687.17455K562CPSF6
chr2109301218109301372+3'-UTR4.634338.82933HepG2FUBP3
chr2109302153109302209+3'-UTR3.9250510.65059K562IGF2BP1
chr2109289424109289487+3'-UTR,CDS,intron-Proximal4.318704.32860K562METAP2
chr2109301311109301377+3'-UTR4.800917.30074K562IGF2BP1
chr2109301377109301505+3'-UTR3.6680811.56537K562IGF2BP1
chr2109302543109302624+3'-UTR4.7480413.37425K562YBX3
chr2109289478109289486+3'-UTR,CDS,intron-Proximal3.247248.42259K562YBX3
chr2109302497109302520+3'-UTR3.456093.88742K562FAM120A
chr2109301743109301828+3'-UTR3.7799412.13863K562FAM120A
chr2109302407109302470+3'-UTR3.645348.55909K562FAM120A
chr2109300637109300683+3'-UTR3.756547.47553K562FAM120A
chr2109302247109302290+3'-UTR4.719595.64683K562YBX3
chr2109301049109301100+3'-UTR4.004194.00100K562TIA1
chr2109302810109302859+3'-UTR4.603119.43510K562UPF1
chr2109301274109301320+3'-UTR3.6596011.60690K562PUM2
chr2109301036109301107+3'-UTR3.2819732.69626K562PUM2
chr2109302810109302858+3'-UTR3.008033.29157K562FAM120A
chr2109300472109300563+3'-UTR3.7530913.72241K562YBX3
chr2109301534109301572+3'-UTR3.054744.13494K562PUM2
chr2109302158109302239+3'-UTR3.258787.43930K562YBX3
chr2109302891109302925+3'-UTR3.523415.35486K562UPF1
chr2109150936109151019+5'-UTR3.329776.75993K562DDX3X
chr2109150974109151010+5'-UTR4.738686.22987HepG2SRSF1
chr2109271427109271511+5'-UTR,intron-Distal3.919583.76295K562LIN28B
chr2109150973109151009+5'-UTR3.305336.59473HepG2GRWD1
chr2109151010109151084+5'-UTR,CDS,intron-Proximal3.056963.43095HepG2SRSF1
chr2109150922109150974+5'-UTR3.711264.17442HepG2SRSF1
chr2109151009109151060+5'-UTR,CDS,intron-Proximal3.257135.74981HepG2GRWD1
chr2109292332109292343+CDS,intron-Proximal3.005877.22304K562YBX3
chr2109292333109292409+CDS,intron-Proximal4.627034.49458K562METAP2
chr2109297172109297227+CDS,intron-Proximal3.140383.87559K562YBX3
chr2109151021109151056+CDS,intron-Proximal3.366973.73423K562UCHL5
chr2109292385109292462+CDS3.019564.35865K562YBX3
chr2109151047109151067+CDS,intron-Proximal4.463793.59236HepG2AQR
chr2109215598109215684+intron-Distal6.3593311.89523K562QKI
chr2109168455109168484+intron-Distal3.550083.14580K562ILF3
chr2109180994109181058+intron-Distal3.176774.25290HepG2CSTF2
chr2109180715109180803+intron-Distal4.3123612.07004HepG2CSTF2
chr2109168431109168490+intron-Distal4.717609.84223HepG2ILF3
chr2109157406109157489+intron-Distal3.406804.49514HepG2XPO5
chr2109168490109168516+intron-Distal4.806216.79267HepG2ILF3
chr2109164934109165049+intron-Distal4.294743.73609HepG2KHSRP
chr2109156378109156465+intron-Distal4.812069.53330K562PTBP1
chr2109172226109172313+intron-Distal3.686587.88662HepG2HNRNPM
chr2109215602109215666+intron-Distal5.4077010.11308HepG2PCBP2
chr2109209837109209873+intron-Distal4.6358014.79954K562PTBP1
chr2109157900109157951+intron-Distal3.265933.42785HepG2HNRNPM
chr2109217375109217473+intron-Distal4.7670919.37190HepG2PTBP1
chr2109152582109152648+intron-Distal3.856155.76537HepG2PCBP2
chr2109173468109173588+intron-Distal4.397688.08956HepG2PCBP2
chr2109217397109217416+intron-Distal4.6833424.70296K562PTBP1
chr2109156370109156461+intron-Distal4.6735914.63885HepG2PTBP1
chr2109212042109212146+intron-Distal4.097748.55611K562KHSRP
chr2109196650109196734+intron-Distal6.5935318.97615HepG2XPO5
chr2109195060109195116+intron-Distal4.596675.87146HepG2HNRNPC
chr2109217416109217455+intron-Distal4.4365021.06121K562PTBP1
chr2109211168109211230+intron-Distal3.695093.37923K562KHDRBS1
chr2109217350109217397+intron-Distal4.8392810.97098K562PTBP1
chr2109209794109209837+intron-Distal4.7967617.77790K562PTBP1
chr2109209792109209872+intron-Distal4.4148316.30459HepG2PTBP1
chr2109156072109156129+intron-Distal3.627164.38996HepG2HNRNPM
chr2109169860109169885+intron-Distal4.475957.56262K562RPS3
chr2109177928109178021+intron-Distal3.115224.24221K562TARDBP
chr2109205936109206043+intron-Distal3.255624.59863HepG2PTBP1
chr2109229911109230016+intron-Distal3.832007.71013HepG2PCBP2
chr2109169046109169143+intron-Distal4.505215.79092K562TARDBP
chr2109160486109160544+intron-Distal3.142624.30137HepG2PTBP1
chr2109175613109175695+intron-Distal3.374824.51091HepG2HNRNPL
chr2109160485109160538+intron-Distal3.478057.16876K562PTBP1
chr2109237558109237660+intron-Distal5.2611311.45916K562LIN28B
chr2109163251109163427+intron-Distal3.248928.11893K562KHSRP
chr2109173064109173108+intron-Distal3.868883.03891HepG2PTBP1
chr2109215601109215683+intron-Distal5.6709122.11754HepG2QKI
chr2109169036109169150+intron-Distal4.2111611.98653K562ILF3
chr2109184467109184553+intron-Distal4.327805.62025K562KHSRP
chr2109209793109209862+intron-Distal3.993073.72005K562MATR3
chr2109162741109162862+intron-Distal3.5550111.44321HepG2HNRNPC
chr2109176173109176258+intron-Distal3.006673.20028K562TARDBP
chr2109212074109212168+intron-Distal4.455193.97018HepG2HNRNPM
chr2109156317109156370+intron-Distal3.101393.45713HepG2PTBP1
chr2109192259109192340+intron-Distal3.728643.08314K562TARDBP
chr2109211675109211782+intron-Distal3.590628.76747HepG2QKI
chr2109217355109217454+intron-Distal3.504254.26619K562MATR3
chr2109244723109244789+intron-Distal4.007303.41738HepG2PTBP1
chr2109167427109167575+intron-Distal3.688503.61097K562ILF3
chr2109211977109212058+intron-Distal4.082345.16181K562PTBP1
chr2109175536109175613+intron-Distal3.564234.88761HepG2HNRNPL
chr2109205226109205321+intron-Distal3.692838.89894K562KHSRP
chr2109151067109151087+intron-Proximal4.338263.25089HepG2AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LIMS1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LIMS1 is not available on ENCORE database.

  • 108 RBPs can affect the levels of LIMS1.  








The Knockdown/knockout RNA-Seq assay for LIMS1 is not available on ENCORE database.





108 RBPs can affect the gene expression of LIMS1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LIMS1ENSG00000169756.121011.994101394.08370-0.462107.870506.95100HepG2ACO1
LIMS1ENSG00000169756.121592.286602399.31960-0.591505.398804.68520HepG2AKAP1
LIMS1ENSG00000169756.121494.205601985.24410-0.409903.318502.45740HepG2ASCC1
LIMS1ENSG00000169756.121913.113702176.71900-0.186201.975101.37810HepG2AUH
LIMS1ENSG00000169756.12696.883201383.07330-0.9889011.615409.63490HepG2BCCIP
LIMS1ENSG00000169756.121081.607801728.05530-0.676006.157305.30500HepG2BOP1
LIMS1ENSG00000169756.121377.107301778.69900-0.369204.034203.12590HepG2CALR
LIMS1ENSG00000169756.121243.256501886.11580-0.601306.558705.40410HepG2CIRBP
LIMS1ENSG00000169756.121114.050601393.80280-0.323204.546403.73430HepG2CKAP4
LIMS1ENSG00000169756.121535.628102075.42310-0.434609.527108.27960HepG2DAZAP1
LIMS1ENSG00000169756.121041.155501289.33780-0.308403.981003.00240HepG2DDX19B
LIMS1ENSG00000169756.121533.891401138.536500.429904.614203.42460HepG2DDX24
LIMS1ENSG00000169756.121652.465302298.38510-0.476004.279303.51580HepG2DDX3X
LIMS1ENSG00000169756.121388.396801740.26090-0.325902.677201.39950HepG2DDX47
LIMS1ENSG00000169756.12817.310801359.83020-0.734506.848005.69590HepG2DDX55
LIMS1ENSG00000169756.121249.295901974.31690-0.660206.459205.54570HepG2DDX6
LIMS1ENSG00000169756.12882.538401221.86660-0.469404.561703.31640HepG2DHX30
LIMS1ENSG00000169756.12794.501501266.87130-0.6731011.3511010.00490HepG2DNAJC21
LIMS1ENSG00000169756.12838.717601255.55680-0.5821012.2415010.97360HepG2DNAJC2
LIMS1ENSG00000169756.12834.455101234.51540-0.565005.368003.81740HepG2EFTUD2
LIMS1ENSG00000169756.121410.602001898.00190-0.428203.492202.83100HepG2EIF2S1
LIMS1ENSG00000169756.121380.384301098.717600.329102.910401.80430HepG2EIF3G
LIMS1ENSG00000169756.121406.736202047.49670-0.5415011.314209.84840HepG2EIF4G1
LIMS1ENSG00000169756.121515.360102499.21600-0.7218020.2397018.86750HepG2ETF1
LIMS1ENSG00000169756.12852.516701074.29840-0.333602.827701.64640HepG2FAM120A
LIMS1ENSG00000169756.121299.052001015.166900.355603.005702.18920HepG2FUBP3
LIMS1ENSG00000169756.121665.568302116.26280-0.345502.562601.89620HepG2FXR1
LIMS1ENSG00000169756.121187.899601963.17730-0.724808.194007.08100HepG2G3BP1
LIMS1ENSG00000169756.121359.084901798.53380-0.404202.606501.98270HepG2GPKOW
LIMS1ENSG00000169756.12562.646901279.00690-1.1847022.7329021.19210HepG2HNRNPA1
LIMS1ENSG00000169756.121503.512601907.35340-0.343204.821603.64160HepG2HNRNPA2B1
LIMS1ENSG00000169756.12697.626901413.21400-1.0185030.1301028.31260HepG2HNRNPU
LIMS1ENSG00000169756.121127.655101995.53860-0.8235011.263409.99840HepG2IGF2BP2
LIMS1ENSG00000169756.121201.669001872.67930-0.640102.714101.74020HepG2IGF2BP3
LIMS1ENSG00000169756.121223.905201443.55850-0.238102.961302.20520HepG2ILF2
LIMS1ENSG00000169756.12972.720801332.80500-0.454403.209501.98640HepG2LARP7
LIMS1ENSG00000169756.121022.188501399.89790-0.453702.698301.50440HepG2LIN28B
LIMS1ENSG00000169756.121241.599302057.98310-0.729009.555208.16190HepG2NOL12
LIMS1ENSG00000169756.12739.821401248.58660-0.755004.250802.87690HepG2NONO
LIMS1ENSG00000169756.121568.069201940.59340-0.307501.998001.37580HepG2PABPC4
LIMS1ENSG00000169756.121584.093401898.16120-0.260903.204702.56060HepG2PCBP1
LIMS1ENSG00000169756.12741.850001049.09930-0.500003.664802.75040HepG2PRPF8
LIMS1ENSG00000169756.121541.822201931.41370-0.325004.313203.66300HepG2PTBP1
LIMS1ENSG00000169756.121386.241501964.51340-0.503006.207805.36240HepG2PUF60
LIMS1ENSG00000169756.121185.692501419.96790-0.260103.018702.38240HepG2PUS1
LIMS1ENSG00000169756.121747.543902091.84620-0.259402.620602.00960HepG2QKI
LIMS1ENSG00000169756.122665.184501533.280200.797505.636304.65160HepG2RAVER1
LIMS1ENSG00000169756.121436.976101895.39500-0.399502.509401.68920HepG2RBM15
LIMS1ENSG00000169756.121890.152102149.50820-0.185501.848301.38640HepG2NELFE
LIMS1ENSG00000169756.121015.938001434.34040-0.497604.221303.40520HepG2RPLP0
LIMS1ENSG00000169756.12904.901601169.66140-0.370303.105802.45910HepG2RPS19
LIMS1ENSG00000169756.12571.302101482.26300-1.3755015.9942014.19380HepG2RPS2
LIMS1ENSG00000169756.12913.085201258.55450-0.462907.521706.53580HepG2SAFB2
LIMS1ENSG00000169756.12896.140601173.99330-0.389602.695601.77000HepG2SERBP1
LIMS1ENSG00000169756.121207.731501467.72930-0.281303.927703.18400HepG2SMN1
LIMS1ENSG00000169756.122341.126101827.856600.356902.253601.36160HepG2SRSF3
LIMS1ENSG00000169756.121502.543701939.65460-0.368405.727604.87400HepG2SRSF5
LIMS1ENSG00000169756.121284.870801707.57210-0.410307.034506.22720HepG2SRSF9
LIMS1ENSG00000169756.121636.845302205.93560-0.430509.354008.32520HepG2SUCLG1
LIMS1ENSG00000169756.12940.561301353.71900-0.525303.910603.12790HepG2SUPV3L1
LIMS1ENSG00000169756.122712.430501886.530300.5238010.026509.06560HepG2TAF15
LIMS1ENSG00000169756.12670.65090907.36810-0.436102.620001.64700HepG2TFIP11
LIMS1ENSG00000169756.121336.083501733.54270-0.375704.002803.00310HepG2TIA1
LIMS1ENSG00000169756.12956.919601385.46660-0.533909.648108.69270HepG2TRIM56
LIMS1ENSG00000169756.121015.651802031.45420-1.0001014.2681012.33360HepG2UBE2L3
LIMS1ENSG00000169756.12761.858001239.66870-0.702404.761903.42950HepG2UPF2
LIMS1ENSG00000169756.121308.702501632.39490-0.318903.867602.64840HepG2UTP18
LIMS1ENSG00000169756.12818.861801332.58700-0.702507.245106.08380HepG2XRN2
LIMS1ENSG00000169756.123976.538102668.020700.575609.108006.96440K562AARS
LIMS1ENSG00000169756.122774.762204095.13990-0.5615016.3594015.10160K562AGGF1
LIMS1ENSG00000169756.122328.080002767.30030-0.249302.851001.32510K562AKAP1
LIMS1ENSG00000169756.123677.698504499.76090-0.291002.718601.74760K562AKAP8
LIMS1ENSG00000169756.122638.720206122.61900-1.2143033.9978032.14320K562AQR
LIMS1ENSG00000169756.122633.360903169.24640-0.267203.391101.90730K562BCCIP
LIMS1ENSG00000169756.124139.896605616.64000-0.440109.802107.72320K562CPEB4
LIMS1ENSG00000169756.123225.003304462.18560-0.468407.333006.04860K562CPSF6
LIMS1ENSG00000169756.129806.621008235.321200.251803.412902.32770K562CELF1
LIMS1ENSG00000169756.126801.499405812.331900.226603.528102.80460K562DDX47
LIMS1ENSG00000169756.122224.105802842.99650-0.354204.938403.01430K562DDX6
LIMS1ENSG00000169756.121790.611704585.56190-1.3566069.4109065.31430K562DKC1
LIMS1ENSG00000169756.123193.648602638.728200.275302.160401.35400K562EFTUD2
LIMS1ENSG00000169756.122612.766003080.17400-0.237403.008701.73760K562EIF2S1
LIMS1ENSG00000169756.123206.948604052.85860-0.337704.488303.59940K562EIF2S2
LIMS1ENSG00000169756.122362.236902929.62070-0.310602.727601.91270K562EIF4A3
LIMS1ENSG00000169756.122224.149602638.33060-0.246402.471001.40020K562EIF4B
LIMS1ENSG00000169756.123959.035502534.127400.643608.171706.07870K562FKBP4
LIMS1ENSG00000169756.123643.240602550.641800.514304.210102.51740K562FUS
LIMS1ENSG00000169756.123147.223304080.90470-0.374804.345902.52090K562G3BP1
LIMS1ENSG00000169756.123485.947502764.096800.334601.973401.38880K562G3BP2
LIMS1ENSG00000169756.122886.502405401.22500-0.9040013.1350011.46770K562GRSF1
LIMS1ENSG00000169756.122209.069303466.49430-0.6500012.2518010.23010K562HNRNPA1
LIMS1ENSG00000169756.122000.372302607.24990-0.382304.130502.70430K562HNRNPF
LIMS1ENSG00000169756.126237.660304263.502400.548906.768904.76370K562HNRNPK
LIMS1ENSG00000169756.123844.045005252.63360-0.450406.376404.70990K562HNRNPL
LIMS1ENSG00000169756.123101.700003838.71720-0.307604.192903.08480K562HNRNPU
LIMS1ENSG00000169756.123753.714806204.97250-0.7251013.1781011.48350K562HSPD1
LIMS1ENSG00000169756.123216.558904341.06410-0.432505.167003.43930K562IGF2BP3
LIMS1ENSG00000169756.124773.212603637.858600.391802.696301.77770K562KRR1
LIMS1ENSG00000169756.123461.294604486.04010-0.374104.373603.31210K562MAGOH
LIMS1ENSG00000169756.122599.946403967.32760-0.6097020.0282018.14510K562MTPAP
LIMS1ENSG00000169756.122183.388202874.56060-0.396803.587401.88330K562NUSAP1
LIMS1ENSG00000169756.123980.786106147.53710-0.627003.973002.47290K562PABPC1
LIMS1ENSG00000169756.124778.334006882.88150-0.526508.317306.07670K562PNPT1
LIMS1ENSG00000169756.123901.156305195.01920-0.413204.450303.37460K562PPIG
LIMS1ENSG00000169756.121395.882202617.95890-0.9073017.7715015.04440K562PSIP1
LIMS1ENSG00000169756.126552.762107773.03650-0.246402.684101.63460K562PUM1
LIMS1ENSG00000169756.126061.874907617.00040-0.329505.249203.90810K562PUM2
LIMS1ENSG00000169756.125082.791304226.191200.266202.110501.62360K562PUS1
LIMS1ENSG00000169756.121995.997602808.81140-0.492804.881902.50050K562RECQL
LIMS1ENSG00000169756.124024.146702661.102900.596607.802505.44000K562SDAD1
LIMS1ENSG00000169756.123587.713704349.56680-0.277803.577202.65780K562SF3A3
LIMS1ENSG00000169756.122621.674504760.94220-0.860804.707102.81680K562SFPQ
LIMS1ENSG00000169756.121724.199402263.98660-0.392902.812701.77830K562SRFBP1
LIMS1ENSG00000169756.123628.478904272.55760-0.235702.189901.55240K562SRSF1
LIMS1ENSG00000169756.123072.565104034.81670-0.393104.073602.75710K562SRSF5
LIMS1ENSG00000169756.124406.383703288.156700.422206.408904.05600K562SRSF9
LIMS1ENSG00000169756.124822.927506004.87890-0.316202.944201.53710K562SSRP1
LIMS1ENSG00000169756.123091.866202486.331400.314402.260201.34760K562SUPV3L1
LIMS1ENSG00000169756.123081.463504171.26800-0.436906.280704.97350K562TIA1
LIMS1ENSG00000169756.121979.653102674.74750-0.434204.567503.28170K562TRIM56
LIMS1ENSG00000169756.123756.787402631.394400.513605.978004.41760K562UCHL5
LIMS1ENSG00000169756.123538.137304674.07550-0.401709.964008.70860K562UPF1
LIMS1ENSG00000169756.122788.356303679.51060-0.400105.020002.76460K562UPF2
LIMS1ENSG00000169756.123478.958704158.88170-0.257504.801403.71440K562WDR43
LIMS1ENSG00000169756.124139.431003080.976700.425905.554603.05010K562ZNF800
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LIMS1 is not available on ENCORE database.





4 RBPs can affect the splicing of LIMS1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELIMS1ENSG00000169756.12chr2+109276060109276220109204921109205084109287236109287303-0.211000.000180.01205excludedK562HNRNPK
SELIMS1ENSG00000169756.12chr2+1092974241092976161092971501092972261093003401093009040.070000.000000.00000includedK562PTBP1
A3SSLIMS1ENSG00000169756.12chr2+1092971291092972261092971501092972261092944341092944830.066000.000110.00098longerK562AQR
A3SSLIMS1ENSG00000169756.12chr2+1092923031092924841092923331092924841092893351092894850.058000.000000.00000longerK562AQR
MXELIMS1ENSG00000169756.12chr2+1092760601092762201092872361092873031092049211092050841092887801092889010.176000.001280.039541includedK562UCHL5
MXELIMS1ENSG00000169756.12chr2+109276060109276220109287236109287303109204766109204881109288780109288901-0.267000.010400.065382includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LIMS1 is not avaliable on ENCORE database.