KYNU

General Information

Gene Name       : KYNU
Gene ID             : ENSG00000115919.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: KYNU)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878KYNUENSG00000115919.1442.0633.1837.62ENCSR000AEF
HepG2KYNUENSG00000115919.1427.4248.3237.87ENCSR985KAT
K562KYNUENSG00000115919.143.993.723.86ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for KYNU is not avaliable on ENCORE database.



Proteins bound to RNA
  • KYNU RNA is bound by 14 proteins.  







eCLIP assay for KYNU is not avaliable on ENCORE database.





14 proteins are bound to KYNU RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2143685279143685300+3'-UTR,CDS4.276507.82199HepG2BCLAF1
chr2143712377143712434+3'-UTR,CDS,intron-Proximal4.469145.79432HepG2BCLAF1
chr2143685300143685312+3'-UTR,CDS,intron-Proximal4.215076.65960HepG2BCLAF1
chr2143635231143635312+5'-UTR,intron-Proximal3.6946510.10035HepG2NCBP2
chr2143798211143798306+CDS,intron-Proximal4.926427.79098HepG2PRPF8
chr2143742657143742707+CDS3.272814.23325HepG2BCLAF1
chr2143718289143718329+CDS4.037598.94445HepG2BCLAF1
chr2143718225143718289+CDS4.6469412.43877HepG2BCLAF1
chr2143642940143643012+CDS4.150823.79347HepG2GRWD1
chr2143676217143676262+CDS,intron-Distal4.014446.81385HepG2BCLAF1
chr2143742700143742749+CDS3.470443.05460HepG2PPIG
chr2143715238143715284+CDS4.530348.41475HepG2BCLAF1
chr2143718219143718285+CDS3.346003.50639HepG2PPIG
chr2143642942143642967+CDS4.837626.04243HepG2BCLAF1
chr2143756079143756141+intron-Distal4.477613.35169HepG2U2AF2
chr2143762373143762484+intron-Distal4.974756.93116HepG2QKI
chr2143671532143671593+intron-Distal4.183804.10336HepG2SUGP2
chr2143777181143777217+intron-Distal4.300214.60209HepG2MATR3
chr2143759899143759949+intron-Distal3.903834.13307HepG2CSTF2
chr2143669567143669660+intron-Distal3.270024.08528HepG2SUGP2
chr2143688309143688363+intron-Distal4.429654.17759HepG2QKI
chr2143776978143777075+intron-Distal4.833666.08412HepG2HNRNPM
chr2143779901143779981+intron-Distal4.308744.02395HepG2KHSRP
chr2143795682143795759+intron-Distal4.875307.27974HepG2QKI
chr2143782241143782299+intron-Distal4.118184.28663HepG2SUGP2
chr2143694326143694385+intron-Distal3.984243.18939HepG2RBFOX2
chr2143723472143723573+intron-Distal4.6267311.56570HepG2PTBP1
chr2143668470143668568+intron-Distal4.366753.07980HepG2HNRNPM
chr2143652823143652981+intron-Distal4.525974.85866HepG2QKI
chr2143663567143663710+intron-Distal5.8948516.04863HepG2PTBP1
chr2143776237143776304+intron-Distal4.272244.61447HepG2SUGP2
chr2143759949143760105+intron-Distal4.690677.17881HepG2CSTF2
chr2143782628143782671+intron-Distal3.444533.30286HepG2PTBP1
chr2143783039143783106+intron-Distal4.214504.36036HepG2SUGP2
chr2143641863143641907+intron-Distal4.557284.17759HepG2QKI
chr2143641798143641863+intron-Distal3.614804.23286HepG2QKI
chr2143753533143753636+intron-Distal3.872343.09122HepG2PTBP1
chr2143777392143777443+intron-Distal3.022843.10640HepG2SUGP2
chr2143705763143705850+intron-Distal4.152054.07628HepG2PTBP1
chr2143780444143780505+intron-Distal3.477613.55754HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for KYNU is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for KYNU is not available on ENCORE database.

  • 99 RBPs can affect the levels of KYNU.  








The Knockdown/knockout RNA-Seq assay for KYNU is not available on ENCORE database.





99 RBPs can affect the gene expression of KYNU :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
KYNUENSG00000115919.10311.74320485.20520-0.638204.876703.49280HepG2AATF
KYNUENSG00000115919.10420.89570597.15700-0.504605.267104.48130HepG2ACO1
KYNUENSG00000115919.10321.65990477.61970-0.570303.831802.68000HepG2ADAR
KYNUENSG00000115919.10473.284801189.83880-1.3300018.6111017.36040HepG2AKAP1
KYNUENSG00000115919.10644.62990925.11160-0.521206.938705.93160HepG2AUH
KYNUENSG00000115919.101129.05070665.052300.763508.177506.95200HepG2CALR
KYNUENSG00000115919.10339.30550858.54710-1.339304.656003.37740HepG2CCAR1
KYNUENSG00000115919.103002.42700935.348501.6825046.6272044.14400HepG2CIRBP
KYNUENSG00000115919.10996.10400597.032600.7384015.0412013.74870HepG2CKAP4
KYNUENSG00000115919.10817.38800580.957300.492503.638702.86010HepG2CPSF6
KYNUENSG00000115919.10337.59390525.07370-0.637205.339003.84130HepG2CPSF7
KYNUENSG00000115919.10298.86950414.33620-0.471302.405601.39930HepG2CSTF2
KYNUENSG00000115919.10571.50400890.40200-0.639708.957007.92430HepG2CELF1
KYNUENSG00000115919.10767.51830552.287200.474706.135704.96300HepG2DDX19B
KYNUENSG00000115919.10790.84930535.657600.562004.933804.05480HepG2DDX21
KYNUENSG00000115919.10927.80010523.909300.8244011.218809.42420HepG2DDX24
KYNUENSG00000115919.10429.54290659.40100-0.618403.663502.78740HepG2DDX55
KYNUENSG00000115919.101066.82330659.720500.693303.735202.60380HepG2DDX59
KYNUENSG00000115919.10827.94840586.355500.497703.032501.98020HepG2DDX5
KYNUENSG00000115919.10761.31870979.02120-0.362801.952201.42570HepG2DDX6
KYNUENSG00000115919.10967.04260571.318900.7592013.0557011.80650HepG2DKC1
KYNUENSG00000115919.10783.20490556.423100.493103.482002.45390HepG2EEF2
KYNUENSG00000115919.10334.15160941.26560-1.4941023.7800022.15710HepG2EIF2S1
KYNUENSG00000115919.10775.09770505.660100.616105.996904.49490HepG2EIF3G
KYNUENSG00000115919.10750.382901012.74030-0.432602.235101.61290HepG2EIF4B
KYNUENSG00000115919.101651.43830944.537800.8059020.0078018.19860HepG2EIF4G1
KYNUENSG00000115919.10780.28430552.361300.498303.681002.43290HepG2ESF1
KYNUENSG00000115919.10774.853701062.12980-0.455005.547604.74550HepG2ETF1
KYNUENSG00000115919.10838.48290583.533900.522903.827202.84490HepG2EWSR1
KYNUENSG00000115919.10256.41130403.68410-0.654805.154203.52240HepG2FAM120A
KYNUENSG00000115919.10318.85320643.92290-1.014009.393208.08580HepG2FIP1L1
KYNUENSG00000115919.10334.30980633.15060-0.921407.107105.37660HepG2FUS
KYNUENSG00000115919.10703.712901049.42130-0.576504.968904.06180HepG2FXR1
KYNUENSG00000115919.10432.84460973.57580-1.1694015.5377014.02220HepG2G3BP1
KYNUENSG00000115919.101418.935201033.466200.457203.812502.75650HepG2G3BP2
KYNUENSG00000115919.10426.86620618.91690-0.536003.406602.27070HepG2GNB2L1
KYNUENSG00000115919.10385.17910570.11730-0.565706.178204.79030HepG2HDGF
KYNUENSG00000115919.10949.73080485.566400.9678013.6484012.38610HepG2HNRNPA1
KYNUENSG00000115919.10613.95430879.88980-0.519206.270904.96050HepG2HNRNPA2B1
KYNUENSG00000115919.10741.22130540.088200.456603.160202.42540HepG2HNRNPC
KYNUENSG00000115919.10749.95020985.63830-0.394302.770502.07240HepG2HNRNPK
KYNUENSG00000115919.10548.56730872.14980-0.6689011.4279010.14210HepG2HNRNPL
KYNUENSG00000115919.101359.86210628.471001.1134018.0150016.61420HepG2HNRNPLL
KYNUENSG00000115919.10345.93660536.51860-0.633107.053706.12120HepG2HNRNPU
KYNUENSG00000115919.10615.70120416.737000.563003.337801.98300HepG2HSPD1
KYNUENSG00000115919.101245.75090989.648300.331902.135401.53290HepG2IGF2BP2
KYNUENSG00000115919.10419.58990606.25530-0.530903.739802.42030HepG2LARP7
KYNUENSG00000115919.101020.00600636.704100.679807.853205.88830HepG2LIN28B
KYNUENSG00000115919.10244.00330472.76180-0.954204.831703.46510HepG2METAP2
KYNUENSG00000115919.10379.060201080.57680-1.5113025.0777023.30380HepG2NCBP2
KYNUENSG00000115919.10478.18810949.38050-0.9894018.2098016.36370HepG2NOL12
KYNUENSG00000115919.101215.06010557.264201.1245018.5117016.78740HepG2NSUN2
KYNUENSG00000115919.10655.73200962.42080-0.553604.434303.53280HepG2PABPC4
KYNUENSG00000115919.10257.59690531.07980-1.0438015.0952013.39150HepG2PARN
KYNUENSG00000115919.10394.76080567.89120-0.524603.698101.69500HepG2PES1
KYNUENSG00000115919.10272.45110373.54720-0.455302.637401.43780HepG2PKM
KYNUENSG00000115919.10637.97640467.927300.447104.269403.33190HepG2PRPF4
KYNUENSG00000115919.101294.70630906.259700.514505.501104.69710HepG2PUF60
KYNUENSG00000115919.10701.62330962.02630-0.455406.568005.73570HepG2PUM1
KYNUENSG00000115919.10566.92470961.32880-0.7619010.892909.61250HepG2PUM2
KYNUENSG00000115919.101551.12470608.244001.3505053.6092051.61160HepG2PUS1
KYNUENSG00000115919.10525.410201084.65830-1.0457020.8905019.40450HepG2QKI
KYNUENSG00000115919.104616.52500578.478802.9964032.7734030.63810HepG2RAVER1
KYNUENSG00000115919.101913.57260887.748601.107909.053608.23950HepG2RBM22
KYNUENSG00000115919.10527.73370984.37770-0.8994013.6821012.24850HepG2RBM25
KYNUENSG00000115919.10525.42970731.02790-0.476402.971101.94220HepG2RBM27
KYNUENSG00000115919.10916.17440593.625300.626005.772304.23610HepG2RCC2
KYNUENSG00000115919.10847.499701114.54990-0.395204.674604.00540HepG2NELFE
KYNUENSG00000115919.101457.70160565.793401.3652028.4527026.76790HepG2RPLP0
KYNUENSG00000115919.10805.48250568.141800.503502.565601.65310HepG2RPS10
KYNUENSG00000115919.10230.73200439.51750-0.929708.822007.79870HepG2RPS19
KYNUENSG00000115919.10499.53210307.173300.701403.085702.24250HepG2RPS3A
KYNUENSG00000115919.10867.32300503.311500.785007.403706.19130HepG2RRP9
KYNUENSG00000115919.101840.14850622.058501.5646039.9822037.70930HepG2SF3B1
KYNUENSG00000115919.10448.65270557.21250-0.312602.433801.82500HepG2SMN1
KYNUENSG00000115919.10393.51000692.15050-0.814705.310104.21680HepG2SNRNP70
KYNUENSG00000115919.103082.602901002.687501.62020105.74800103.78100HepG2SRFBP1
KYNUENSG00000115919.101173.62330669.347300.810002.693701.70660HepG2SRSF3
KYNUENSG00000115919.10655.94180894.78940-0.448004.774103.98900HepG2SRSF5
KYNUENSG00000115919.10653.92490515.938200.341802.323501.68090HepG2SRSF7
KYNUENSG00000115919.101793.66580870.584401.0428036.3427034.97440HepG2SSB
KYNUENSG00000115919.10631.03930978.18320-0.632409.181508.25590HepG2TAF15
KYNUENSG00000115919.10846.13230612.581000.465903.633002.81670HepG2TARDBP
KYNUENSG00000115919.10756.68580440.021000.782007.515206.01520HepG2TFIP11
KYNUENSG00000115919.10470.66750898.86890-0.9334015.0879013.17350HepG2TIA1
KYNUENSG00000115919.10253.64580525.98480-1.0522016.3211015.10600HepG2TRIM56
KYNUENSG00000115919.10634.56510885.36370-0.480504.416803.28160HepG2TUFM
KYNUENSG00000115919.101166.29320550.780301.0823015.6006014.05900HepG2U2AF1
KYNUENSG00000115919.10680.61520937.13460-0.461402.958702.09520HepG2UBE2L3
KYNUENSG00000115919.10250.27520387.81270-0.631803.729102.84840HepG2UCHL5
KYNUENSG00000115919.10820.47480648.307300.339703.169402.53650HepG2UTP3
KYNUENSG00000115919.10283.48780568.75210-1.004507.375705.37020HepG2XRCC5
KYNUENSG00000115919.101094.25760646.209300.759808.328607.08620HepG2XRN2
KYNUENSG00000115919.101208.47420738.521800.7104016.8579015.79170HepG2ZNF622
KYNUENSG00000115919.1075.10590203.37290-1.437108.272307.34600K562AQR
KYNUENSG00000115919.1069.54060115.78830-0.735602.296501.52310K562FIP1L1
KYNUENSG00000115919.10136.39570205.26780-0.589702.262401.57600K562GRSF1
KYNUENSG00000115919.1098.79380153.98900-0.640302.539301.73320K562MAGOH
KYNUENSG00000115919.1080.41590153.68660-0.934404.576903.36170K562MATR3
KYNUENSG00000115919.1084.67520146.65540-0.792403.154002.40370K562SRSF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for KYNU is not available on ENCORE database.





12 RBPs can affect the splicing of KYNU :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEKYNUENSG00000115919.10chr2+1437947041437948421437908041437908901437979961437982270.051000.000590.05164includedHepG2QKI
SEKYNUENSG00000115919.10chr2+1436370311436372301436352521436353051436761771436762980.167000.000010.00118includedHepG2HNRNPL
SEKYNUENSG00000115919.10chr2+143676177143676298143635225143635305143685227143685310-0.087000.000060.00323excludedHepG2SF3A3
SEKYNUENSG00000115919.10chr2+1436389131436389991436352321436353051436429171436431050.150000.000010.00569includedHepG2NOL12
SEKYNUENSG00000115919.10chr2+143676177143676298143635225143635305143685227143685310-0.064000.000890.04252excludedHepG2SF3B4
SEKYNUENSG00000115919.10chr2+143642917143643105143635225143635305143676177143676298-0.197000.000450.02073excludedHepG2HNRNPC
SEKYNUENSG00000115919.10chr2+1436389131436389991436352321436353051436429171436431050.141000.000020.01280includedHepG2FUS
MXEKYNUENSG00000115919.10chr2+143642917143643105143685227143685310143635225143635305143712378143712440-0.152000.000960.020622includedHepG2U2AF1
MXEKYNUENSG00000115919.10chr2+143642917143643105143676177143676298143635225143635305143685227143685310-0.080000.002610.044712includedHepG2U2AF1
MXEKYNUENSG00000115919.10chr2+1436389131436389991436761771436762981436352321436353051436852271436853100.077000.000390.032991includedHepG2NOL12
MXEKYNUENSG00000115919.10chr2+1437152091437152841437181921437183391437137711437138431437426521437427510.124000.002560.060221includedHepG2XRN2
MXEKYNUENSG00000115919.10chr2+143642917143643105143676177143676298143635225143635305143685227143685310-0.114000.001400.045012includedHepG2HNRNPC
MXEKYNUENSG00000115919.10chr2+143642917143643105143676177143676298143635225143635305143685227143685310-0.117000.000570.054672includedHepG2SSB
MXEKYNUENSG00000115919.10chr2+143638913143638999143642923143643105143635232143635305143676177143676298-0.185000.001090.056472includedHepG2DDX6
MXEKYNUENSG00000115919.10chr2+143642917143643105143676177143676298143635225143635305143685227143685310-0.137000.000940.030372includedHepG2TIAL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for KYNU is not avaliable on ENCORE database.