FAM98B

General Information

Gene Name       : FAM98B
Gene ID             : ENSG00000171262.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FAM98B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FAM98BENSG00000171262.1129.0824.9927.03ENCSR000AEF
HepG2FAM98BENSG00000171262.118.0919.5213.80ENCSR985KAT
K562FAM98BENSG00000171262.1121.3022.8722.09ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
FAM98BA305-818A-M1BGKcLV40-47, Submitted, ENCORE2


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
FAM98BK562CRISPRFAM98B-BGKcLV40-47,FAM98B-BGKcLV40-48NT-BGKcLV40-1,NT-BGKcLV40-287.3,84.7SubmittingENCORE2
FAM98BHepG2CRISPRBGHcLV41-67,BGHcLV41-68BGHcLV41-1,BGHcLV41-20.0,0.0NotSatisfiedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
FAM98BProduct_ID: A305-818A-M
Lot_ID: 1
Source: Bethyl Labs
Target Name: FAM98B-human		 FAM98B-K562-CRISPR-A305-818A.png<br>Caption: Western blot following CRISPR against FAM98B in K562 whole cell lysate using FAM98B specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against FAM98B. FAM98B protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.








RNA Targets

  • eCLIP assay for FAM98B is not avaliable on ENCORE database.



Proteins bound to RNA
  • FAM98B RNA is bound by 25 proteins.  







eCLIP assay for FAM98B is not avaliable on ENCORE database.





25 proteins are bound to FAM98B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr153877826938778376+3'-UTR3.832999.96973K562PABPC4
chr153877769438777744+3'-UTR4.222264.77152K562IGF2BP1
chr153877701638777096+3'-UTR4.494714.55651HepG2SUB1
chr153877534338775473+3'-UTR,intron-Distal5.147518.90415K562KHSRP
chr153877685738776923+3'-UTR3.642213.72790K562APOBEC3C
chr153877731738777381+3'-UTR3.102147.43517K562PUM2
chr153877684438776883+3'-UTR,CDS3.7158610.71674K562GTF2F1
chr153877732238777383+3'-UTR4.893767.35095K562IGF2BP1
chr153877708338777155+3'-UTR3.887725.74545K562CPEB4
chr153877683838776914+3'-UTR,CDS3.748576.64080K562FAM120A
chr153877683438776958+3'-UTR,CDS4.626149.58152K562CSTF2T
chr153877685038776918+3'-UTR,CDS4.7447915.36764K562PABPC4
chr153877684738776933+3'-UTR,CDS3.746318.05415K562DDX6
chr153877761938777694+3'-UTR4.932436.42531K562IGF2BP1
chr153874635238746436+5'-UTR,CDS,intron-Proximal3.4419110.87648K562DDX3X
chr153877668238776805+CDS,intron-Distal,intron-Proximal4.373603.69819HepG2CSTF2T
chr153877668638776755+CDS,intron-Distal,intron-Proximal8.3972936.72600K562FASTKD2
chr153877668938776743+CDS,intron-Distal,intron-Proximal4.026193.00997K562TAF15
chr153875746838757532+CDS,intron-Proximal4.154854.72426K562LIN28B
chr153877668238776788+CDS,intron-Distal,intron-Proximal8.0825969.69399HepG2FAM120A
chr153877668538776772+CDS,intron-Distal,intron-Proximal4.479483.31330K562UPF1
chr153877674438776802+CDS,intron-Proximal4.0826611.48348K562AKAP8L
chr153877675538776800+CDS,intron-Proximal4.8952316.21927K562FASTKD2
chr153877674138776795+CDS,intron-Proximal6.1953732.53231K562FAM120A
chr153877667938776740+CDS,intron-Distal,intron-Proximal5.222478.72707K562EWSR1
chr153877668438776744+CDS,intron-Distal,intron-Proximal3.9133425.09311K562AKAP8L
chr153877668838776736+CDS,intron-Distal,intron-Proximal3.913163.29554HepG2GTF2F1
chr153877668638776743+CDS,intron-Distal,intron-Proximal6.9583732.74275K562CSTF2T
chr153877668738776781+CDS,intron-Distal,intron-Proximal3.9163711.73986K562DROSHA
chr153877675638776795+CDS,intron-Proximal5.5247511.59176K562CSTF2T
chr153877668538776790+CDS,intron-Distal,intron-Proximal7.6576358.10980K562GTF2F1
chr153877668838776792+CDS,intron-Distal,intron-Proximal4.921946.90365K562DDX6
chr153877669338776746+CDS,intron-Proximal4.598575.19527K562DDX21
chr153877668738776746+CDS,intron-Distal,intron-Proximal3.464954.59403K562GPKOW
chr153877356738773589+CDS,intron-Distal3.072805.99226K562YBX3
chr153875629938756360+CDS4.450986.03393K562YBX3
chr153877668338776705+CDS,intron-Distal,intron-Proximal6.1392529.35220K562FAM120A
chr153877668238776797+CDS,intron-Distal,intron-Proximal4.783383.90256HepG2PRPF4
chr153877668738776785+CDS,intron-Distal,intron-Proximal5.8880010.29245K562APOBEC3C
chr153877645038776513+CDS,intron-Distal,intron-Proximal3.978893.70701HepG2PRPF4
chr153877668538776769+CDS,intron-Distal,intron-Proximal5.451868.10759K562FTO
chr153877668138776798+CDS,intron-Distal,intron-Proximal3.301963.43596K562EIF4G2
chr153877618438776310+intron-Distal3.950793.24603K562KHSRP
chr153876552538765597+intron-Distal4.091993.24603K562KHSRP
chr153876224138762358+intron-Distal,intron-Proximal3.921353.02234K562KHSRP
chr153876517838765271+intron-Distal4.358585.19823K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FAM98B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FAM98B is not available on ENCORE database.

  • 90 RBPs can affect the levels of FAM98B.  








The Knockdown/knockout RNA-Seq assay for FAM98B is not available on ENCORE database.





90 RBPs can affect the gene expression of FAM98B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FAM98BENSG00000171262.72081.43900963.435501.111207.516706.68470HepG2AKAP1
FAM98BENSG00000171262.7339.64260723.19180-1.0904014.2501013.04010HepG2BOP1
FAM98BENSG00000171262.7359.58040663.94220-0.884709.194008.01050HepG2CPSF6
FAM98BENSG00000171262.7892.681701072.59420-0.264902.865702.11230HepG2DAZAP1
FAM98BENSG00000171262.7427.30550633.27910-0.567604.733303.87230HepG2DDX21
FAM98BENSG00000171262.7582.04740922.90440-0.665005.886505.00590HepG2DDX3X
FAM98BENSG00000171262.7429.57370792.77970-0.884008.195807.18510HepG2DDX6
FAM98BENSG00000171262.7391.18240572.29960-0.548904.355603.48960HepG2DNAJC21
FAM98BENSG00000171262.7323.72930567.26990-0.8092011.9113010.66030HepG2DNAJC2
FAM98BENSG00000171262.7345.06690762.13250-1.1432013.9388012.67620HepG2EIF2S1
FAM98BENSG00000171262.7479.93370842.25290-0.811407.364106.32160HepG2EIF4A3
FAM98BENSG00000171262.7472.05210820.03830-0.796705.824504.85130HepG2EIF4B
FAM98BENSG00000171262.7717.676901058.13910-0.560108.459707.14380HepG2EIF4G1
FAM98BENSG00000171262.7788.521801013.63690-0.362302.540101.75720HepG2EIF4G2
FAM98BENSG00000171262.7905.522201324.78020-0.548908.772007.80400HepG2ETF1
FAM98BENSG00000171262.7244.62380644.26130-1.3971012.3212010.86730HepG2FIP1L1
FAM98BENSG00000171262.7462.83170752.66520-0.701505.596704.70720HepG2GPKOW
FAM98BENSG00000171262.7293.51880577.78260-0.9771010.757609.60970HepG2HNRNPA1
FAM98BENSG00000171262.7410.14620642.68430-0.648005.497204.54690HepG2HNRNPC
FAM98BENSG00000171262.7441.38770652.50590-0.563906.198905.18340HepG2HNRNPF
FAM98BENSG00000171262.7713.83310977.06560-0.452906.477005.48760HepG2HNRNPL
FAM98BENSG00000171262.7215.91240718.27910-1.7341027.3840025.74520HepG2HNRNPLL
FAM98BENSG00000171262.7391.01760642.53400-0.716507.654406.50560HepG2IGF2BP1
FAM98BENSG00000171262.7584.53360801.29740-0.455103.053502.34880HepG2IGF2BP2
FAM98BENSG00000171262.7443.35710652.13850-0.556707.614006.46110HepG2ILF2
FAM98BENSG00000171262.7453.59450575.73040-0.344002.898801.86140HepG2KIF1C
FAM98BENSG00000171262.7603.62110850.07370-0.493903.505402.76650HepG2MAGOH
FAM98BENSG00000171262.7389.70920521.64310-0.420702.077001.37120HepG2MSI2
FAM98BENSG00000171262.7237.49200874.97370-1.8814032.9325030.95640HepG2NCBP2
FAM98BENSG00000171262.7513.30870779.23380-0.602204.766403.83050HepG2PABPC4
FAM98BENSG00000171262.7437.18870569.43130-0.381302.873502.12510HepG2PPIL4
FAM98BENSG00000171262.7793.670901077.73490-0.441406.842805.99580HepG2PUM1
FAM98BENSG00000171262.7730.501501076.95730-0.560006.840705.80240HepG2PUM2
FAM98BENSG00000171262.7506.76960641.48790-0.340102.909702.28180HepG2PUS1
FAM98BENSG00000171262.71023.56590793.505200.367203.414902.73070HepG2QKI
FAM98BENSG00000171262.7294.83600671.63600-1.187808.482007.29060HepG2RAVER1
FAM98BENSG00000171262.7410.27490702.87960-0.776708.043106.97240HepG2RPLP0
FAM98BENSG00000171262.7308.25670403.67380-0.389102.012701.48060HepG2RPS19
FAM98BENSG00000171262.7369.29010600.73420-0.702002.544801.78700HepG2RRP9
FAM98BENSG00000171262.7430.22210568.54960-0.402203.462102.75560HepG2SAFB2
FAM98BENSG00000171262.7295.22700405.16310-0.456702.333601.46650HepG2SERBP1
FAM98BENSG00000171262.7304.49450645.44520-1.083909.720408.39550HepG2SF3A3
FAM98BENSG00000171262.7912.76290762.817200.258802.083401.55920HepG2SF3B4
FAM98BENSG00000171262.7721.55910973.45070-0.432005.819004.86380HepG2SLBP
FAM98BENSG00000171262.7328.38990655.22610-0.996604.679002.64150HepG2SLTM
FAM98BENSG00000171262.7453.06090663.01700-0.549306.782105.84420HepG2SMN1
FAM98BENSG00000171262.7488.98150684.59840-0.485502.650601.71520HepG2SMNDC1
FAM98BENSG00000171262.71618.60950796.238801.0234030.8738029.66960HepG2SRSF1
FAM98BENSG00000171262.7799.729601002.40940-0.325903.390702.71010HepG2SRSF5
FAM98BENSG00000171262.7475.58800641.05880-0.430703.928203.12030HepG2SRSF7
FAM98BENSG00000171262.7519.93770647.80220-0.317202.482001.95280HepG2SRSF9
FAM98BENSG00000171262.7788.295901085.84130-0.462006.419805.69780HepG2SSB
FAM98BENSG00000171262.7301.43330435.22490-0.529902.172801.33430HepG2SUPT6H
FAM98BENSG00000171262.71013.76810715.753400.502106.056905.28060HepG2TAF15
FAM98BENSG00000171262.7300.66650700.00710-1.2192011.7574010.41980HepG2TARDBP
FAM98BENSG00000171262.7351.32200620.32880-0.8202010.050609.20110HepG2TIAL1
FAM98BENSG00000171262.7344.97070625.90600-0.8595013.0305011.93390HepG2TRIM56
FAM98BENSG00000171262.7806.45260991.84720-0.298502.130301.37160HepG2TUFM
FAM98BENSG00000171262.7767.76640551.249100.477902.965202.31580HepG2U2AF1
FAM98BENSG00000171262.7633.326401049.83810-0.729106.513005.19680HepG2UBE2L3
FAM98BENSG00000171262.7284.99010462.77280-0.699402.575601.84410HepG2UCHL5
FAM98BENSG00000171262.7471.19300572.41130-0.280701.965401.36020HepG2UPF1
FAM98BENSG00000171262.7509.19720771.03790-0.598601.926101.31390HepG2XRN2
FAM98BENSG00000171262.7368.90920629.54270-0.7710011.8656010.93000HepG2ZNF622
FAM98BENSG00000171262.71908.990301600.214600.254402.964402.37970K562AGGF1
FAM98BENSG00000171262.71672.930202018.45360-0.270903.319302.26620K562BCLAF1
FAM98BENSG00000171262.71028.772601497.92350-0.542005.412104.18020K562BOP1
FAM98BENSG00000171262.72056.848002463.87770-0.260502.346301.33480K562CPEB4
FAM98BENSG00000171262.7887.583301592.74030-0.843607.617606.31070K562CPSF6
FAM98BENSG00000171262.71269.707901531.29740-0.270302.440201.45630K562CSTF2
FAM98BENSG00000171262.71164.326801637.03720-0.491605.828504.25280K562DDX3X
FAM98BENSG00000171262.72115.862901791.789400.239702.492901.66700K562DKC1
FAM98BENSG00000171262.71385.359901798.23590-0.376305.468903.73700K562EIF2S1
FAM98BENSG00000171262.71478.744402248.50820-0.604605.864804.87620K562EIF2S2
FAM98BENSG00000171262.71452.382201752.06540-0.270602.909702.09440K562EIF3G
FAM98BENSG00000171262.7913.664401710.33400-0.9045015.8571013.77290K562EIF4A3
FAM98BENSG00000171262.71214.873101540.28130-0.342403.716002.34440K562EIF4B
FAM98BENSG00000171262.71229.334201492.96900-0.280302.620501.36780K562EWSR1
FAM98BENSG00000171262.71103.508401694.52500-0.618807.794406.29910K562FIP1L1
FAM98BENSG00000171262.71038.304901620.54090-0.642207.783406.30540K562FMR1
FAM98BENSG00000171262.71028.273201373.53950-0.417703.229202.23520K562FTO
FAM98BENSG00000171262.71266.329901548.90550-0.290602.739701.40840K562FUS
FAM98BENSG00000171262.72398.155801898.616600.336901.918301.34130K562G3BP2
FAM98BENSG00000171262.71082.098201520.68940-0.490905.306604.21310K562GPKOW
FAM98BENSG00000171262.72056.973802996.68950-0.542803.230002.41560K562GRSF1
FAM98BENSG00000171262.7821.578401415.14240-0.784509.164008.12860K562HNRNPC
FAM98BENSG00000171262.71884.904702303.91860-0.289602.574801.55700K562HNRNPL
FAM98BENSG00000171262.71867.666902297.44750-0.298802.369301.62930K562HSPD1
FAM98BENSG00000171262.7981.079601484.35650-0.597407.571606.08950K562METAP2
FAM98BENSG00000171262.73005.609803766.16830-0.325402.412501.36070K562MSI2
FAM98BENSG00000171262.71190.882801707.82460-0.520107.067905.13520K562NCBP2
FAM98BENSG00000171262.71635.476501856.10710-0.182602.287401.60290K562NSUN2
FAM98BENSG00000171262.71475.573101923.58880-0.382503.340202.42360K562PPIG
FAM98BENSG00000171262.7876.944601268.76300-0.532903.388202.37250K562PSIP1
FAM98BENSG00000171262.73296.103104017.70250-0.285603.680302.57200K562PUM2
FAM98BENSG00000171262.72445.715301651.350300.566503.582702.97650K562PUS1
FAM98BENSG00000171262.71998.861601608.961200.312903.521002.86530K562RBM15
FAM98BENSG00000171262.7939.159201157.29060-0.301302.198001.31750K562RCC2
FAM98BENSG00000171262.71219.741701584.12270-0.377102.294501.55300K562RPS19
FAM98BENSG00000171262.7826.991101211.26830-0.550603.420402.29720K562RPS3
FAM98BENSG00000171262.7714.527401831.43000-1.3579048.6470045.91220K562SF3A3
FAM98BENSG00000171262.7822.180801097.11070-0.416203.305202.15820K562SRFBP1
FAM98BENSG00000171262.71643.256502227.12720-0.438603.439602.65650K562SRSF1
FAM98BENSG00000171262.71045.199901505.91530-0.526903.613402.43620K562SUPV3L1
FAM98BENSG00000171262.71467.472501049.177900.484004.233803.21220K562SYNCRIP
FAM98BENSG00000171262.71655.367402254.28320-0.445503.001802.26500K562TARDBP
FAM98BENSG00000171262.71645.128202174.43580-0.402402.939502.09270K562TIA1
FAM98BENSG00000171262.7934.706001220.37310-0.384702.218601.38930K562TIAL1
FAM98BENSG00000171262.7954.481501296.16360-0.441503.972502.79610K562TRIM56
FAM98BENSG00000171262.73465.615704346.30170-0.326702.972101.51450K562UBE2L3
FAM98BENSG00000171262.71214.838901593.64640-0.391602.888501.84270K562UCHL5
FAM98BENSG00000171262.71384.271301968.06580-0.5077010.443709.16190K562UPF1
FAM98BENSG00000171262.7929.704201684.01820-0.8571016.2157014.09070K562WDR3
FAM98BENSG00000171262.71271.098201622.49450-0.352102.431301.32300K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FAM98B is not available on ENCORE database.





1 RBPs can affect the splicing of FAM98B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFAM98BENSG00000171262.7chr15+387574693875760438746354387464333876242738762606-0.068000.000320.00461excludedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FAM98B is not avaliable on ENCORE database.