FAM98A

General Information

Gene Name       : FAM98A
Gene ID             : ENSG00000119812.18
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FAM98A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FAM98AENSG00000119812.18262.36156.90209.63ENCSR000AEF
HepG2FAM98AENSG00000119812.1849.3175.7462.52ENCSR985KAT
K562FAM98AENSG00000119812.18222.68160.13191.41ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
FAM98AA305-817A-M1BGHcLV41-65, Submitted, ENCORE2BGKcLV40-45, Submitted, ENCORE2


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
FAM98AK562CRISPRFAM98A-BGKcLV40-45,FAM98A-BGKcLV40-46NT-BGKcLV40-1,NT-BGKcLV40-293.808,93.2015SubmittingENCORE2
FAM98AHepG2CRISPRFAM98A-BGHcLV41-65,FAM98A-BGHcLV41-66NT-BGHcLV41-1,NT-BGHcLV41-267.0,58.3SubmittingENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
FAM98AProduct_ID: A305-817A-M
Lot_ID: 1
Source: Bethyl Labs
Target Name: FAM98A-human		 FAM98A-HEPG2-CRISPR-A305-817A-M.png<br>Caption: Western blot following CRISPR against FAM98A in HepG2 whole cell lysate using FAM98A specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against FAM98A. FAM98A protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.
 FAM98A-K562-CRISPR-A305-817A.png<br>Caption: Western blot following CRISPR against FAM98A in K562 whole cell lysate using FAM98A specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against FAM98A. FAM98A protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.








RNA Targets

  • eCLIP assay for FAM98A is not avaliable on ENCORE database.



Proteins bound to RNA
  • FAM98A RNA is bound by 10 proteins.  







eCLIP assay for FAM98A is not avaliable on ENCORE database.





10 proteins are bound to FAM98A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr23380971633809779-3'-UTR,intron-Distal,intron-Proximal3.859775.10007K562FAM120A
chr23380927833809350-3'-UTR,intron-Distal3.766135.35486K562UPF1
chr23380971333809763-3'-UTR,intron-Distal,intron-Proximal4.146695.48330K562UPF1
chr23381720333817281-5'-UTR,CDS,intron-Distal3.509894.22917HepG2PPIG
chr23382062533820693-5'-UTR,CDS,intron-Distal4.590125.56813HepG2PPIG
chr23382057033820704-5'-UTR,CDS,intron-Distal3.618724.41784HepG2GRWD1
chr23382419933824297-5'-UTR,CDS,intron-Distal4.347413.79199HepG2PPIG
chr23381710733817267-5'-UTR,CDS,intron-Distal,intron-Proximal5.120944.02817HepG2PRPF8
chr23382063233820707-5'-UTR,CDS,intron-Distal,intron-Proximal3.507033.43213K562UCHL5
chr23381166633811732-CDS,intron-Distal,intron-Proximal3.533783.57857HepG2BCLAF1
chr23381060233810677-CDS,intron-Distal,intron-Proximal5.3165810.50400K562LIN28B
chr23381059633810765-CDS,intron-Distal,intron-Proximal3.168164.79538HepG2BCLAF1
chr23381660333816749-intron-Distal3.678595.35459K562KHSRP
chr23382387533823945-intron-Distal4.734195.68967HepG2PCBP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FAM98A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FAM98A is not available on ENCORE database.

  • 104 RBPs can affect the levels of FAM98A.  








The Knockdown/knockout RNA-Seq assay for FAM98A is not available on ENCORE database.





104 RBPs can affect the gene expression of FAM98A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FAM98AENSG00000119812.14796.304401035.89640-0.379502.686401.70230HepG2ADAR
FAM98AENSG00000119812.141683.206901240.233600.440503.037702.48320HepG2AKAP1
FAM98AENSG00000119812.141806.788001385.219300.383203.765902.13900HepG2ATP5C1
FAM98AENSG00000119812.141429.877301853.72360-0.374505.753404.82470HepG2AUH
FAM98AENSG00000119812.141483.974302253.65010-0.602804.056203.34780HepG2BOP1
FAM98AENSG00000119812.141858.292201385.004600.424005.094904.08720HepG2CALR
FAM98AENSG00000119812.141005.222501740.87360-0.792307.698206.05400HepG2CCAR1
FAM98AENSG00000119812.14744.11590974.94170-0.389802.603201.85190HepG2CIRBP
FAM98AENSG00000119812.14389.94090794.92450-1.027607.984506.69450HepG2CNOT7
FAM98AENSG00000119812.141014.269301264.08840-0.317702.347801.33040HepG2CPSF7
FAM98AENSG00000119812.14543.68230829.24840-0.609003.736502.50450HepG2CSTF2
FAM98AENSG00000119812.142499.358101475.172900.7606020.8118019.38150HepG2CELF1
FAM98AENSG00000119812.141255.014501586.21610-0.337905.445504.45290HepG2DAZAP1
FAM98AENSG00000119812.141292.411401063.794500.280702.526501.42150HepG2DDX1
FAM98AENSG00000119812.141687.593701234.870500.450503.665002.20780HepG2DDX27
FAM98AENSG00000119812.141715.907801188.020200.530304.791003.98540HepG2DDX3X
FAM98AENSG00000119812.141244.89940974.052700.353902.740801.44930HepG2DDX47
FAM98AENSG00000119812.14692.122501043.12370-0.591808.462007.28530HepG2DNAJC21
FAM98AENSG00000119812.141140.71890858.099600.410602.880601.94170HepG2EEF2
FAM98AENSG00000119812.14927.23380715.282800.374302.436701.39830HepG2EFTUD2
FAM98AENSG00000119812.141382.65140981.061900.494904.077503.36700HepG2EIF2S1
FAM98AENSG00000119812.141016.69340696.542400.545504.520503.38540HepG2EIF3D
FAM98AENSG00000119812.142061.743901564.862400.397706.352305.17580HepG2EIF4G1
FAM98AENSG00000119812.14984.875502128.36620-1.1117040.9150039.11430HepG2ETF1
FAM98AENSG00000119812.141454.47750945.047700.621908.073406.31400HepG2FASTKD2
FAM98AENSG00000119812.141132.106202072.45070-0.872304.210402.95860HepG2FTO
FAM98AENSG00000119812.141782.216902345.59110-0.396302.638002.01020HepG2GPKOW
FAM98AENSG00000119812.14493.61110735.80350-0.575903.264802.04880HepG2GRSF1
FAM98AENSG00000119812.141008.066501457.75720-0.532208.947107.44770HepG2HNRNPA2B1
FAM98AENSG00000119812.14626.420501171.37750-0.9030013.2017011.79270HepG2HNRNPC
FAM98AENSG00000119812.141432.610401990.71650-0.474608.465407.29960HepG2HNRNPF
FAM98AENSG00000119812.141571.097101027.664500.612306.964105.89190HepG2HNRNPK
FAM98AENSG00000119812.141378.633502238.42490-0.699206.086905.19220HepG2HNRNPLL
FAM98AENSG00000119812.141413.528501069.384100.402404.039202.91020HepG2HNRNPM
FAM98AENSG00000119812.14325.103601163.63450-1.8397071.0509068.45640HepG2HNRNPU
FAM98AENSG00000119812.141472.981401960.29850-0.412304.788203.86110HepG2IGF2BP1
FAM98AENSG00000119812.141558.378801031.465300.595306.071805.10890HepG2IGF2BP2
FAM98AENSG00000119812.141574.23380968.062400.701402.442901.52580HepG2IGF2BP3
FAM98AENSG00000119812.14846.485001107.70020-0.388005.492704.07240HepG2KIF1C
FAM98AENSG00000119812.141705.562401143.374700.576804.114102.57750HepG2KRR1
FAM98AENSG00000119812.142818.478501837.875900.616805.372904.20170HepG2LARP4
FAM98AENSG00000119812.141395.71180903.007000.628107.667405.85670HepG2LARP7
FAM98AENSG00000119812.141606.732501094.351200.554005.110104.22740HepG2MAGOH
FAM98AENSG00000119812.141953.779001100.459600.828109.797108.66720HepG2MATR3
FAM98AENSG00000119812.141212.42880728.963900.733902.322201.35680HepG2METAP2
FAM98AENSG00000119812.141647.321302282.51840-0.470502.760501.79420HepG2MTPAP
FAM98AENSG00000119812.141879.479501126.368100.738605.037704.19400HepG2NCBP2
FAM98AENSG00000119812.14712.475101572.88630-1.1425030.4060028.12430HepG2NOL12
FAM98AENSG00000119812.141327.228301984.66420-0.580504.562803.60850HepG2NSUN2
FAM98AENSG00000119812.141238.04230726.451600.769004.852403.65000HepG2PABPC1
FAM98AENSG00000119812.141567.362401003.042400.643906.626005.51650HepG2PABPC4
FAM98AENSG00000119812.141436.229801151.823900.318303.755902.78650HepG2PARN
FAM98AENSG00000119812.141978.437301043.695700.9226029.7058028.07740HepG2PCBP1
FAM98AENSG00000119812.14783.214201037.87250-0.406204.447403.53340HepG2PPIL4
FAM98AENSG00000119812.14700.420401018.31930-0.539903.780202.85400HepG2PRPF8
FAM98AENSG00000119812.141702.693801062.051300.6809015.9262014.82040HepG2PTBP1
FAM98AENSG00000119812.141262.108601501.44560-0.250501.812301.31650HepG2PUF60
FAM98AENSG00000119812.14985.983001593.83670-0.6929019.3759018.09270HepG2PUM1
FAM98AENSG00000119812.14837.512901592.68130-0.9273019.7980018.09690HepG2PUM2
FAM98AENSG00000119812.141124.509001778.91130-0.6617012.8799011.92640HepG2RBM22
FAM98AENSG00000119812.141616.667701043.847100.631008.018006.92120HepG2RBM25
FAM98AENSG00000119812.141321.49520884.216700.579604.841403.42960HepG2RCC2
FAM98AENSG00000119812.141377.974801181.918000.221302.059301.57790HepG2NELFE
FAM98AENSG00000119812.141082.695802144.32280-0.9859019.4247017.94620HepG2RPLP0
FAM98AENSG00000119812.14840.64800677.811300.310501.897801.38030HepG2RPS19
FAM98AENSG00000119812.14577.11200797.88880-0.467302.552601.78340HepG2RPS3A
FAM98AENSG00000119812.14771.397501036.27970-0.425905.739704.86440HepG2SAFB2
FAM98AENSG00000119812.141389.63250680.218301.0305016.2133014.06330HepG2SERBP1
FAM98AENSG00000119812.141409.460502215.69990-0.652604.858003.94540HepG2SF3B1
FAM98AENSG00000119812.141218.503601439.62340-0.240602.798402.09270HepG2SLBP
FAM98AENSG00000119812.141908.322101183.671200.688905.800204.38000HepG2SMNDC1
FAM98AENSG00000119812.141577.256702465.31820-0.644404.566703.55350HepG2SNRNP70
FAM98AENSG00000119812.142975.890301154.086201.3665073.7415072.06510HepG2SRSF1
FAM98AENSG00000119812.141095.168102383.81240-1.122109.582407.62370HepG2SRSF3
FAM98AENSG00000119812.141424.312001955.77470-0.457508.046306.96140HepG2SRSF7
FAM98AENSG00000119812.142112.641901744.432300.276203.721203.14620HepG2SSB
FAM98AENSG00000119812.141703.943501154.249000.561803.159401.73570HepG2SUGP2
FAM98AENSG00000119812.141226.50270880.616700.477903.664502.53680HepG2TFIP11
FAM98AENSG00000119812.141159.82500953.157000.283002.262501.50460HepG2TIA1
FAM98AENSG00000119812.142417.472901325.835000.8665014.2580012.79630HepG2U2AF1
FAM98AENSG00000119812.141135.224001459.48480-0.362505.053604.15310HepG2UPF1
FAM98AENSG00000119812.141947.416801409.078700.466708.863307.89030HepG2UTP3
FAM98AENSG00000119812.141106.468101344.21530-0.280803.439702.70370HepG2ZC3H8
FAM98AENSG00000119812.142240.352901605.157100.4809012.4996011.54730HepG2ZNF622
FAM98AENSG00000119812.142818.440701956.836500.526306.850005.78520K562AKAP8L
FAM98AENSG00000119812.142805.250902053.165800.450207.502805.88660K562ATP5C1
FAM98AENSG00000119812.141263.343801655.63050-0.390105.879204.46370K562BCLAF1
FAM98AENSG00000119812.141473.117701889.70040-0.359303.157901.77990K562CIRBP
FAM98AENSG00000119812.141540.998403065.43970-0.992208.917606.98840K562CNOT7
FAM98AENSG00000119812.141706.830102549.57110-0.578905.869104.73180K562CPSF6
FAM98AENSG00000119812.141489.188302021.72340-0.441104.080502.59140K562DDX21
FAM98AENSG00000119812.141240.827402234.23220-0.8485014.3623012.91770K562EIF2S2
FAM98AENSG00000119812.14872.673101279.35400-0.551908.076705.96440K562EIF4B
FAM98AENSG00000119812.142209.961403717.52860-0.7503021.8505019.39400K562EIF4G2
FAM98AENSG00000119812.141720.243702593.93630-0.592505.383004.18380K562FMR1
FAM98AENSG00000119812.141489.487102198.51180-0.561705.028303.75400K562FTO
FAM98AENSG00000119812.142019.792101477.416800.451007.268206.35080K562FXR1
FAM98AENSG00000119812.141650.419302027.30990-0.296703.322502.07110K562GLRX3
FAM98AENSG00000119812.141097.604602977.56990-1.4398025.5413023.14470K562GRSF1
FAM98AENSG00000119812.14818.372001588.31640-0.956706.314705.44840K562HNRNPC
FAM98AENSG00000119812.142705.317301760.921300.619407.364505.25910K562HNRNPK
FAM98AENSG00000119812.14884.717802297.25110-1.3766051.8769048.52350K562HNRNPU
FAM98AENSG00000119812.142544.680001536.942200.7273012.255709.32730K562LARP7
FAM98AENSG00000119812.141791.213402376.10730-0.407703.324902.36450K562METAP2
FAM98AENSG00000119812.143146.779703962.55400-0.332602.902101.73970K562MSI2
FAM98AENSG00000119812.141050.824602131.45370-1.0203037.3621035.02140K562MTPAP
FAM98AENSG00000119812.141779.718002368.22680-0.4122010.514409.18810K562NSUN2
FAM98AENSG00000119812.141667.569102248.93810-0.431503.630202.67640K562PCBP3
FAM98AENSG00000119812.141376.028201725.01300-0.326103.025802.18710K562POLR2G
FAM98AENSG00000119812.142541.676501800.352000.497407.120406.09280K562PTBP1
FAM98AENSG00000119812.143337.283504056.13520-0.281402.470801.70160K562PUF60
FAM98AENSG00000119812.142769.824004314.11760-0.6393013.7785011.34480K562PUM1
FAM98AENSG00000119812.142429.595804227.20420-0.7990025.2552022.59820K562PUM2
FAM98AENSG00000119812.142921.521501940.746400.590007.267006.43400K562PUS1
FAM98AENSG00000119812.142510.402701890.880900.408805.928705.08770K562RBM15
FAM98AENSG00000119812.141681.640901298.690500.372702.866601.85760K562RCC2
FAM98AENSG00000119812.141907.820502734.49040-0.519303.036001.37260K562RPS3A
FAM98AENSG00000119812.142060.810901537.025900.423004.648303.23820K562SAFB
FAM98AENSG00000119812.141725.745201194.434300.530803.258101.55480K562SERBP1
FAM98AENSG00000119812.14891.282901167.70300-0.389703.057501.72470K562SLBP
FAM98AENSG00000119812.142472.761501764.971800.486406.701805.61040K562SRSF1
FAM98AENSG00000119812.14954.658601260.19580-0.400603.624702.39640K562SRSF4
FAM98AENSG00000119812.141103.133701400.07870-0.343903.885102.33030K562SSB
FAM98AENSG00000119812.142521.580501730.232000.543304.298303.26770K562SYNCRIP
FAM98AENSG00000119812.142270.560901705.907100.412403.184802.00030K562U2AF1
FAM98AENSG00000119812.142378.977903076.42010-0.370902.957901.71150K562UTP3
FAM98AENSG00000119812.141581.795302148.65220-0.441905.383404.14180K562WDR3
FAM98AENSG00000119812.141850.942802234.35750-0.271604.069503.05750K562WDR43
FAM98AENSG00000119812.142275.177903164.68950-0.476105.990604.64220K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FAM98A is not available on ENCORE database.





2 RBPs can affect the splicing of FAM98A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFAM98AENSG00000119812.14chr2-338134013381362433812306338123873381714633817281-0.065000.008810.07337excludedK562AQR
SEFAM98AENSG00000119812.14chr2-338134013381358633812306338123873381714633817281-0.066000.006170.08183excludedK562HNRNPC
A3SSFAM98AENSG00000119812.14chr2-3381714633817301338171463381728133820555338207040.072000.000000.00000longerK562AQR
A5SSFAM98AENSG00000119812.14chr2-338171463381730133817249338173013381340133813586-0.081000.000280.00647shorterK562AQR
MXEFAM98AENSG00000119812.14chr2-33810596338107643381162833811765338099553381051133812306338123870.053000.000000.000031includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FAM98A is not avaliable on ENCORE database.