DLEU2

General Information

Gene Name       : DLEU2
Gene ID             : ENSG00000231607.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DLEU2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DLEU2ENSG00000231607.1015.3813.7314.55ENCSR000AEF
HepG2DLEU2ENSG00000231607.106.4614.4410.45ENCSR985KAT
K562DLEU2ENSG00000231607.1026.2027.0126.61ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DLEU2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • DLEU2 RNA is bound by 28 proteins.  







eCLIP assay for DLEU2 is not avaliable on ENCORE database.





28 proteins are bound to DLEU2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr135062147150621534-intron-Distal4.630165.08856K562ILF3
chr135061830950618337-intron-Distal3.626424.70224K562KHSRP
chr135061818850618212-intron-Distal5.6623512.71898K562KHSRP
chr135062317350623215-intron-Distal6.3731333.58852K562DGCR8
chr135067315950673226-intron-Distal3.761063.04224HepG2SUGP2
chr135062118750621292-intron-Distal4.6691813.57962HepG2DGCR8
chr135069904950699168-intron-Distal3.315174.32983K562NONO
chr135062301650623082-intron-Distal5.3463920.12446HepG2DROSHA
chr135062284450622900-intron-Distal3.6565611.18324HepG2DROSHA
chr135065605150656126-intron-Distal,intron-Proximal3.335375.04173HepG2NCBP2
chr135066137150661464-intron-Distal4.950134.24565HepG2HNRNPL
chr135062317650623231-intron-Distal,intron-Proximal6.2475040.41746HepG2DROSHA
chr135069895350699021-intron-Distal4.329123.82670HepG2SFPQ
chr135061577750615817-intron-Distal5.4794210.09004HepG2QKI
chr135062101750621071-intron-Distal3.5076210.04256HepG2DGCR8
chr135062352950623562-intron-Distal3.769346.46385HepG2DROSHA
chr135069949650699599-intron-Distal3.076745.77609HepG2NKRF
chr135062086750620980-intron-Distal3.987976.37574HepG2KHSRP
chr135065568150655757-intron-Distal4.078544.36329HepG2PRPF4
chr135062759750627660-intron-Distal3.831473.10466K562SAFB2
chr135061825650618309-intron-Distal4.103283.47043HepG2KHSRP
chr135061886650618922-intron-Distal,intron-Proximal3.117883.33947HepG2U2AF2
chr135062099050621148-intron-Distal5.1086426.97306HepG2DROSHA
chr135062329550623381-intron-Distal,intron-Proximal,polyA_site5.8617430.32874HepG2DROSHA
chr135062148150621526-intron-Distal3.690836.06026K562DGCR8
chr135069842750698507-intron-Distal4.6108211.02458HepG2CSTF2T
chr135062093550620989-intron-Distal3.580266.25417HepG2DGCR8
chr135066595250666025-intron-Distal4.046165.38424HepG2HNRNPL
chr135069867450698747-intron-Distal4.022889.07337HepG2FAM120A
chr135069817050698259-intron-Distal4.3070011.90626HepG2CSTF2T
chr135062351750623571-intron-Distal4.188244.00239HepG2KHSRP
chr135066696150667041-intron-Distal4.822324.40847HepG2PTBP1
chr135062095950621011-intron-Distal3.119053.57533K562KHSRP
chr135062311750623154-intron-Distal6.5574413.73594K562DROSHA
chr135069953050699616-intron-Distal3.7118811.02501HepG2CSTF2T
chr135065568250655794-intron-Distal3.369323.99385K562CSTF2T
chr135069907550699168-intron-Distal4.072004.35952HepG2PRPF4
chr135062338850623397-intron-Distal4.421654.94796HepG2DROSHA
chr135062300150623105-intron-Distal7.2649623.55471K562DROSHA
chr135062294050622985-intron-Distal3.550849.77872HepG2DROSHA
chr135062107250621140-intron-Distal3.417078.17208HepG2DGCR8
chr135064844650648543-intron-Distal3.492464.70224K562KHSRP
chr135067260050672681-intron-Distal4.718805.54528HepG2QKI
chr135061821250618241-intron-Distal5.8799716.54184K562KHSRP
chr135062269250622745-intron-Distal5.4455012.76584HepG2DROSHA
chr135065623750656305-intron-Distal4.030803.40087HepG2RBFOX2
chr135061840950618474-intron-Distal,intron-Proximal3.093637.03713K562KHSRP
chr135069812550698170-intron-Distal3.931615.85439HepG2CSTF2T
chr135062113250621197-intron-Distal3.670306.57673K562KHSRP
chr135062326350623273-intron-Distal,intron-Proximal8.1442372.32449K562DGCR8
chr135062333650623360-intron-Distal5.5568020.65214HepG2DGCR8
chr135062085550620935-intron-Distal4.1514611.11336HepG2DGCR8
chr135062326450623300-intron-Distal,intron-Proximal7.94614105.30496HepG2DGCR8
chr135062318450623233-intron-Distal,intron-Proximal5.1190510.14821K562KHSRP
chr135065566150655779-intron-Distal4.142258.06348HepG2CSTF2T
chr135061860250618667-intron-Distal,intron-Proximal4.103146.41317HepG2QKI
chr135069864850698730-intron-Distal3.393093.25653K562CSTF2T
chr135069922150699286-intron-Distal4.392225.09405K562NONO
chr135062154550621607-intron-Distal3.875104.25630HepG2DROSHA
chr135062351050623574-intron-Distal3.566618.01175HepG2U2AF2
chr135061795850618011-intron-Distal,intron-Proximal3.643983.41398HepG2CSTF2
chr135066586550665931-intron-Distal3.701334.88448HepG2HNRNPL
chr135062315450623173-intron-Distal6.8594122.53896K562DGCR8
chr135062305650623072-intron-Distal3.691348.67954K562KHSRP
chr135061818650618237-intron-Distal3.327013.78824HepG2KHSRP
chr135062318350623225-intron-Distal4.313196.69328HepG2HNRNPUL1
chr135062240550622418-intron-Distal3.629174.26550HepG2DROSHA
chr135062109350621159-intron-Distal4.023173.22073HepG2KHSRP
chr135062752050627597-intron-Distal3.902153.84033K562SAFB2
chr135065570050655797-intron-Distal4.095036.32422K562DROSHA
chr135062310350623180-intron-Distal8.94278221.12200HepG2DGCR8
chr135061813150618188-intron-Distal3.981509.07651K562KHSRP
chr135064227550642343-intron-Distal,intron-Proximal5.446646.90654K562SF3B4
chr135061377850613831-intron-Distal4.704318.18285HepG2XPO5
chr135069933150699356-intron-Distal3.553084.45183HepG2CSTF2T
chr135062155950621601-intron-Distal3.244433.69464K562DGCR8
chr135062327350623312-intron-Distal,intron-Proximal8.2782481.09527K562DGCR8
chr135062264950622692-intron-Distal3.350648.59768HepG2DROSHA
chr135062156850621602-intron-Distal3.086264.94627HepG2DGCR8
chr135069931850699414-intron-Distal4.866307.46616K562CSTF2T
chr135069952750699613-intron-Distal4.152383.31153K562GTF2F1
chr135062083950620990-intron-Distal4.7450829.13172HepG2DROSHA
chr135066572050665795-intron-Distal4.582434.07272K562AGGF1
chr135062301150623102-intron-Distal5.6506711.30624K562GEMIN5
chr135062220050622242-intron-Distal3.985528.04579HepG2DGCR8
chr135062142650621465-intron-Distal3.272084.58697K562DGCR8
chr135065582250655906-intron-Distal3.816075.84589K562EFTUD2
chr135069895350699016-intron-Distal4.516309.56617HepG2CSTF2T
chr135062298550623016-intron-Distal4.6089615.76366HepG2DROSHA
chr135062311650623154-intron-Distal9.13127242.84952K562DGCR8
chr135061824150618309-intron-Distal3.9396313.11913K562KHSRP
chr135066724850667317-intron-Distal4.399104.85866HepG2QKI
chr135066516850665271-intron-Distal3.863553.16986HepG2QKI
chr135062307450623089-intron-Distal3.9075112.83520K562KHSRP
chr135062308950623120-intron-Distal4.1688911.66098K562KHSRP
chr135065572050655900-intron-Distal3.310895.62662K562BUD13
chr135069867550698725-intron-Distal3.463884.96675K562TIA1
chr135062318050623220-intron-Distal8.0231761.36867HepG2DGCR8
chr135061632050616365-intron-Distal4.235316.54646HepG2QKI
chr135062140650621469-intron-Distal3.118324.75229HepG2ILF3
chr135062317150623215-intron-Distal6.2649611.80331K562DROSHA
chr135062120250621302-intron-Distal3.433367.76123HepG2DROSHA
chr135069866850698741-intron-Distal3.402478.20886HepG2NKRF
chr135062270850622730-intron-Distal3.925925.29296K562DROSHA
chr135069798050698087-intron-Distal4.509455.09405K562NONO
chr135062312050623166-intron-Distal6.0208912.76584HepG2DROSHA
chr135062336050623372-intron-Distal4.4232319.39784HepG2DGCR8
chr135062330150623326-intron-Distal,intron-Proximal,polyA_site6.4989917.98352HepG2DGCR8
chr135066585950665923-intron-Distal4.907184.62242K562AGGF1
chr135062038150620438-intron-Distal3.331754.32806HepG2DGCR8
chr135069867950698729-intron-Distal4.805575.16036HepG2CSTF2T
chr135065570250655787-intron-Distal3.998123.29554HepG2GTF2F1
chr135061833750618409-intron-Distal3.097386.49723K562KHSRP
chr135069924150699292-intron-Distal4.297608.28918HepG2CSTF2T
chr135069828450698356-intron-Distal4.429119.06344HepG2CSTF2T
chr135061573650615777-intron-Distal4.4162314.33890HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DLEU2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DLEU2 is not available on ENCORE database.

  • 90 RBPs can affect the levels of DLEU2.  








The Knockdown/knockout RNA-Seq assay for DLEU2 is not available on ENCORE database.





90 RBPs can affect the gene expression of DLEU2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DLEU2ENSG00000231607.464.07740123.34890-0.944903.868103.08170HepG2AUH
DLEU2ENSG00000231607.436.8213095.76740-1.379004.301203.13120HepG2BCCIP
DLEU2ENSG00000231607.438.1294083.21020-1.125903.074102.12480HepG2BCLAF1
DLEU2ENSG00000231607.411.2957086.86030-2.9429011.7884010.66790HepG2BOP1
DLEU2ENSG00000231607.417.8608070.20570-1.974807.175606.19700HepG2CKAP4
DLEU2ENSG00000231607.430.4984079.74220-1.386603.965203.15530HepG2CPSF6
DLEU2ENSG00000231607.450.08980108.81750-1.119304.577703.78790HepG2CELF1
DLEU2ENSG00000231607.461.19900117.03900-0.935404.060703.19050HepG2DAZAP1
DLEU2ENSG00000231607.433.6565094.16150-1.484304.668403.69230HepG2DDX55
DLEU2ENSG00000231607.448.26170141.60300-1.552907.129206.23870HepG2ETF1
DLEU2ENSG00000231607.4141.4185081.987300.786402.536701.79580HepG2FIP1L1
DLEU2ENSG00000231607.434.6862078.37270-1.176003.047001.71700HepG2FKBP4
DLEU2ENSG00000231607.424.9747079.87950-1.677403.568102.40890HepG2FTO
DLEU2ENSG00000231607.463.5252030.144801.075302.272001.64270HepG2FXR1
DLEU2ENSG00000231607.469.0346029.691201.217202.924402.00600HepG2G3BP2
DLEU2ENSG00000231607.421.8527090.39320-2.048407.217806.21530HepG2GPKOW
DLEU2ENSG00000231607.422.8162054.00780-1.243102.401701.75150HepG2HNRNPC
DLEU2ENSG00000231607.449.4486088.01050-0.831702.527701.84110HepG2HNRNPF
DLEU2ENSG00000231607.423.9247086.26400-1.850306.115605.21990HepG2HNRNPLL
DLEU2ENSG00000231607.469.4371030.155501.203202.843102.17960HepG2MAGOH
DLEU2ENSG00000231607.466.13850116.05380-0.811203.073802.27040HepG2NOL12
DLEU2ENSG00000231607.432.5090076.49010-1.234403.012702.23290HepG2NSUN2
DLEU2ENSG00000231607.424.4036060.91560-1.319703.260302.13550HepG2PCBP2
DLEU2ENSG00000231607.461.2595029.557901.051302.461401.30660HepG2PKM
DLEU2ENSG00000231607.417.7109072.62630-2.035906.139804.98860HepG2PRPF8
DLEU2ENSG00000231607.434.21230110.77430-1.695007.632706.70830HepG2PUF60
DLEU2ENSG00000231607.476.90810117.58090-0.612402.239401.69400HepG2PUM1
DLEU2ENSG00000231607.426.68730118.35770-2.1489010.549209.68160HepG2RBM22
DLEU2ENSG00000231607.4139.1211056.274401.305704.785303.38150HepG2RCC2
DLEU2ENSG00000231607.467.9840035.221900.948602.156001.66640HepG2NELFE
DLEU2ENSG00000231607.467.8454032.809601.048002.565101.96770HepG2RECQL
DLEU2ENSG00000231607.422.1917094.81750-2.095108.561707.46150HepG2RPLP0
DLEU2ENSG00000231607.427.2251057.74930-1.084902.234201.38330HepG2RPS10
DLEU2ENSG00000231607.49.1993034.77290-1.918403.391802.71940HepG2RPS19
DLEU2ENSG00000231607.417.3969071.84130-2.046005.885404.78440HepG2RRP9
DLEU2ENSG00000231607.422.3253085.38380-1.935306.603905.55180HepG2SF3B1
DLEU2ENSG00000231607.463.17540106.19290-0.749302.576101.89590HepG2SLBP
DLEU2ENSG00000231607.444.9945095.00460-1.078202.617201.85830HepG2SNRNP70
DLEU2ENSG00000231607.436.71280133.68730-1.8645010.427509.62350HepG2SRFBP1
DLEU2ENSG00000231607.4169.2377034.391902.2988016.1931015.25130HepG2SRSF1
DLEU2ENSG00000231607.450.9007086.46940-0.764502.305401.66570HepG2SRSF7
DLEU2ENSG00000231607.476.19280124.38410-0.707102.633102.02300HepG2SUCLG1
DLEU2ENSG00000231607.413.5400055.41560-2.033104.750203.53370HepG2SUPT6H
DLEU2ENSG00000231607.428.7581093.73290-1.704605.640604.72820HepG2SUPV3L1
DLEU2ENSG00000231607.422.8912084.08270-1.877006.364905.32540HepG2TARDBP
DLEU2ENSG00000231607.416.7587062.82380-1.906405.490804.15530HepG2TFIP11
DLEU2ENSG00000231607.420.5807052.15250-1.341403.078402.55550HepG2TIAL1
DLEU2ENSG00000231607.412.1951052.59680-2.108705.913205.14410HepG2TRIM56
DLEU2ENSG00000231607.432.5565063.62160-0.966602.360501.70700HepG2UPF1
DLEU2ENSG00000231607.430.6401065.40010-1.093902.780001.73090HepG2UTP18
DLEU2ENSG00000231607.4111.1347064.647200.781502.264701.30940HepG2XRCC6
DLEU2ENSG00000231607.453.1794092.26990-0.795001.917301.30670HepG2XRN2
DLEU2ENSG00000231607.46.7799069.97270-3.3675010.270809.38490HepG2ZNF622
DLEU2ENSG00000231607.4278.13260179.059300.635203.367802.05010K562AARS
DLEU2ENSG00000231607.4337.31720479.77420-0.508203.198701.86780K562ABCF1
DLEU2ENSG00000231607.4155.89870227.94290-0.548102.465701.84820K562AKAP8L
DLEU2ENSG00000231607.4687.88410448.811600.616003.622302.17960K562APOBEC3C
DLEU2ENSG00000231607.4147.16140472.24950-1.682204.958904.21450K562AQR
DLEU2ENSG00000231607.4147.61000222.93850-0.594902.964901.97290K562BCLAF1
DLEU2ENSG00000231607.487.51510231.79860-1.405309.565607.89320K562BOP1
DLEU2ENSG00000231607.4202.74990334.16830-0.720904.172802.36660K562BUD13
DLEU2ENSG00000231607.4125.79150325.62650-1.372202.471101.47720K562CNOT7
DLEU2ENSG00000231607.457.18530246.47220-2.1077020.9810018.80340K562CPSF6
DLEU2ENSG00000231607.4104.85920169.13200-0.689702.519201.51570K562CSTF2
DLEU2ENSG00000231607.4324.97000245.309900.405602.142501.38310K562DKC1
DLEU2ENSG00000231607.4311.83170205.705500.600103.004901.66650K562EEF2
DLEU2ENSG00000231607.497.59220198.79950-1.026503.590102.54100K562EFTUD2
DLEU2ENSG00000231607.495.65050160.92630-0.750603.167201.80510K562EXOSC5
DLEU2ENSG00000231607.4154.96210250.77220-0.694503.526702.55700K562FMR1
DLEU2ENSG00000231607.489.16670212.54880-1.253207.556105.96710K562FTO
DLEU2ENSG00000231607.4360.55490138.663701.3785016.1892014.83430K562FXR1
DLEU2ENSG00000231607.4235.98280160.368400.557202.168701.55370K562G3BP2
DLEU2ENSG00000231607.4174.61020246.67940-0.498502.480601.40490K562GLRX3
DLEU2ENSG00000231607.493.66250235.32340-1.329109.560908.07200K562GPKOW
DLEU2ENSG00000231607.4231.11310541.45520-1.228202.070701.41010K562GRSF1
DLEU2ENSG00000231607.4152.52140229.93660-0.592202.999301.87880K562HNRNPA1
DLEU2ENSG00000231607.499.61990196.06480-0.976804.496203.75380K562HNRNPC
DLEU2ENSG00000231607.4469.98820223.219501.0741010.057407.64870K562HNRNPK
DLEU2ENSG00000231607.441.33560200.92880-2.2812015.0397012.70920K562KRR1
DLEU2ENSG00000231607.4116.48290229.70060-0.979605.985104.66930K562METAP2
DLEU2ENSG00000231607.4165.09010259.34850-0.651603.897502.95190K562MTPAP
DLEU2ENSG00000231607.4140.18250288.17510-1.039609.491408.22110K562NSUN2
DLEU2ENSG00000231607.480.55170212.74660-1.401105.583304.04070K562PABPN1
DLEU2ENSG00000231607.4101.01660204.69890-1.018904.892203.78900K562PCBP3
DLEU2ENSG00000231607.471.44030157.02470-1.136204.761203.70930K562POLR2G
DLEU2ENSG00000231607.4293.62040391.45900-0.414902.117701.40390K562PPIG
DLEU2ENSG00000231607.4411.51950228.175100.850704.231603.42660K562PTBP1
DLEU2ENSG00000231607.4232.45620152.161400.611303.052001.64810K562RBM25
DLEU2ENSG00000231607.4111.47060261.74850-1.231504.645102.51320K562RBM39
DLEU2ENSG00000231607.4223.47790144.628300.627702.916801.43000K562SDAD1
DLEU2ENSG00000231607.4159.31700284.33200-0.835706.204205.02170K562SF3A3
DLEU2ENSG00000231607.4110.04800223.78970-1.024005.320103.94220K562SF3B1
DLEU2ENSG00000231607.4102.60850166.80340-0.701003.183102.26480K562SF3B4
DLEU2ENSG00000231607.494.45530237.34260-1.329305.546503.41790K562SFPQ
DLEU2ENSG00000231607.4120.66580223.42000-0.888702.707601.49630K562SNRNP200
DLEU2ENSG00000231607.4148.12060223.67760-0.594602.713502.01250K562SRSF1
DLEU2ENSG00000231607.4268.16170157.481000.767802.747801.93100K562SYNCRIP
DLEU2ENSG00000231607.494.68230169.07680-0.836503.273602.25030K562TIAL1
DLEU2ENSG00000231607.486.92910179.53130-1.046304.998803.63620K562TRIM56
DLEU2ENSG00000231607.4257.68720403.48080-0.646904.168202.35900K562TRIP6
DLEU2ENSG00000231607.4292.67950155.503600.912302.308901.32220K562U2AF1
DLEU2ENSG00000231607.4276.93140160.583500.786105.491904.36320K562U2AF2
DLEU2ENSG00000231607.4238.44700305.55700-0.357801.939001.32970K562UPF1
DLEU2ENSG00000231607.4175.85000261.45750-0.572203.002402.09290K562WDR3
DLEU2ENSG00000231607.4343.94080194.733200.820603.644501.75710K562XRCC6
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DLEU2 is not available on ENCORE database.





6 RBPs can affect the splicing of DLEU2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDLEU2ENSG00000231607.4chr13-5064471750644777506422325064229950649694506497890.141000.000400.04874includedK562FMR1
SEDLEU2ENSG00000231607.4chr13-506237195062379850618050506189045064223250642318-0.124000.008020.06814excludedK562AQR
SEDLEU2ENSG00000231607.4chr13-506034135060362850601268506015425061878650618904-0.461000.009190.07592excludedK562AQR
SEDLEU2ENSG00000231607.4chr13-506496945064978950642232506422995065595850656114-0.246000.000130.00214excludedK562AQR
SEDLEU2ENSG00000231607.4chr13-5064471750644777506422325064229950649694506497890.108000.000040.01405includedK562DROSHA
SEDLEU2ENSG00000231607.4chr13-5064471750644777506422325064229950649694506497890.120000.003700.04927includedK562PUS1
SEDLEU2ENSG00000231607.4chr13-5064565150645765506422325064229950649694506497890.063000.000070.03269includedK562PPIL4
SEDLEU2ENSG00000231607.4chr13-5064969450649789506422325064229950655958506561080.234000.000110.06640includedK562AARS

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DLEU2 is not avaliable on ENCORE database.