DGKZ

General Information

Gene Name       : DGKZ
Gene ID             : ENSG00000149091.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DGKZ)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DGKZENSG00000149091.155.2319.7512.49ENCSR000AEF
HepG2DGKZENSG00000149091.1532.859.5321.19ENCSR985KAT
K562DGKZENSG00000149091.1547.8032.8140.30ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DGKZ is not avaliable on ENCORE database.



Proteins bound to RNA
  • DGKZ RNA is bound by 17 proteins.  







eCLIP assay for DGKZ is not avaliable on ENCORE database.





17 proteins are bound to DGKZ RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr114640051346400555+3'-UTR,CDS,intron-Proximal4.618607.15298K562AQR
chr114639659246396631+3'-UTR,CDS,intron-Distal,intron-Proximal4.580484.02817HepG2PRPF8
chr114638914846389218+3'-UTR,CDS,intron-Distal,intron-Proximal3.083274.26200K562GTF2F1
chr114639419846394229+3'-UTR,CDS,intron-Distal,intron-Proximal4.485233.79199HepG2PPIG
chr114639875846398828+3'-UTR,CDS,intron-Proximal4.229215.10672HepG2DDX59
chr114638928046389343+3'-UTR,CDS,intron-Distal,intron-Proximal5.056304.68690HepG2PRPF8
chr114639278146392870+3'-UTR,CDS,intron-Distal,intron-Proximal4.854638.69408K562SF3B4
chr114639769246397742+3'-UTR,CDS,intron-Distal,intron-Proximal4.054257.08947HepG2PRPF8
chr114638927046389300+3'-UTR,CDS,intron-Distal,intron-Proximal4.884416.46301HepG2PPIG
chr114639638146396434+3'-UTR,CDS,intron-Distal,intron-Proximal4.951736.35567HepG2PRPF8
chr114639615346396212+3'-UTR,CDS,intron-Distal,intron-Proximal4.054524.66686K562DDX24
chr114639637346396389+3'-UTR,CDS,intron-Distal4.205183.82843HepG2PPIG
chr114639873046398812+3'-UTR,CDS,intron-Proximal3.345484.34707HepG2HNRNPK
chr114639620646396217+3'-UTR,CDS,intron-Distal,intron-Proximal4.602673.49905HepG2PPIG
chr114639648346396524+3'-UTR,CDS,intron-Distal,intron-Proximal4.584685.52963HepG2PPIG
chr114639364646393717+3'-UTR,CDS,intron-Distal4.997667.06060HepG2PPIG
chr114639362346393646+3'-UTR,CDS,intron-Distal,intron-Proximal4.937704.97342HepG2PPIG
chr114639754646397633+3'-UTR,CDS,intron-Distal,intron-Proximal5.000819.23542K562EFTUD2
chr114640004846400141+3'-UTR,CDS,intron-Proximal5.1598126.58915K562AQR
chr114639105546391110+3'-UTR,CDS,intron-Distal,intron-Proximal4.316383.20743HepG2PPIG
chr114639328146393345+3'-UTR,CDS,intron-Distal,intron-Proximal5.419607.65840HepG2PPIG
chr114640202346402091+3'-UTR5.855666.59792K562PABPC4
chr114640099446401048+3'-UTR,CDS,intron-Proximal3.344186.16312K562AQR
chr114639636046396389+3'-UTR,CDS,intron-Distal4.245235.23082K562DDX24
chr114639415846394226+3'-UTR,CDS,intron-Distal,intron-Proximal3.325643.39477K562BUD13
chr114639617946396206+3'-UTR,CDS,intron-Distal4.859955.27053HepG2PPIG
chr114638309946383154+5'-UTR,intron-Distal4.227313.28464K562EWSR1
chr114638309846383159+5'-UTR,intron-Distal3.012823.01436K562CSTF2T
chr114636904146369157+5'-UTR,intron-Distal4.040456.96497HepG2DDX3X
chr114638310146383164+5'-UTR,intron-Distal3.127674.68402HepG2CSTF2T
chr114638310646383176+5'-UTR,intron-Distal4.756985.91582K562NONO
chr114638954546389584+CDS,intron-Distal,intron-Proximal4.590124.97342HepG2PPIG
chr114639922746399300+intron-Distal4.204834.36307HepG2HNRNPK
chr114639908546399141+intron-Distal5.338576.17200HepG2PCBP2
chr114639718146397237+intron-Distal,intron-Proximal4.895795.26064K562AQR
chr114639769946397768+intron-Distal,intron-Proximal4.992114.09264K562AQR
chr114639899746399086+intron-Distal4.269474.33022HepG2HNRNPK
chr114638396546384023+intron-Distal4.157063.82910K562NONO
chr114639939646399470+intron-Distal3.345403.45841K562HNRNPK
chr114636995346369982+intron-Distal3.972453.82910K562NONO
chr114639924346399338+intron-Distal4.050427.57201K562HNRNPK
chr114638300446383041+intron-Distal4.044643.53896K562NONO
chr114636960646369758+intron-Distal3.411126.36039K562EWSR1
chr114640015246400189+intron-Distal3.631423.54718K562PRPF8
chr114638962946389725+intron-Distal,intron-Proximal4.006667.79506K562AQR
chr114639921546399297+intron-Distal3.395774.78882K562IGF2BP2
chr114636963146369685+intron-Distal4.088376.75450K562NONO
chr114639903146399085+intron-Distal4.331705.76537HepG2PCBP2
chr114639756246397613+intron-Distal,intron-Proximal4.316195.16342K562SF3B4
chr114636982446369869+intron-Distal4.181153.53896K562NONO
chr114639893746399031+intron-Distal5.3927716.52088HepG2PCBP2
chr114639816346398228+intron-Distal,intron-Proximal4.734654.96013K562PRPF8
chr114639935846399477+intron-Distal3.614725.54538HepG2PCBP2
chr114639902746399136+intron-Distal4.344787.85389K562HNRNPK
chr114639919346399246+intron-Distal4.909215.11777HepG2DDX59
chr114639895346399027+intron-Distal4.865105.62822K562HNRNPK
chr114636938346369534+intron-Distal,intron-Proximal4.5962410.80246K562NONO
chr114639276946392857+intron-Distal,intron-Proximal5.181839.77805HepG2SF3B4
chr114636971246369774+intron-Distal4.684706.16396K562NONO
chr114639896346399077+intron-Distal4.192739.86810HepG2DDX59
chr114640006746400145+intron-Proximal3.362956.40795K562PRPF8
chr114639883946398858+intron-Proximal4.547463.78681HepG2PCBP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DGKZ is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DGKZ is not available on ENCORE database.

  • 112 RBPs can affect the levels of DGKZ.  








The Knockdown/knockout RNA-Seq assay for DGKZ is not available on ENCORE database.





112 RBPs can affect the gene expression of DGKZ :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DGKZENSG00000149091.11891.25360509.602700.806402.296501.44670HepG2BCCIP
DGKZENSG00000149091.11466.19440652.77860-0.485702.609501.85990HepG2CALR
DGKZENSG00000149091.111036.63690777.173700.415505.764804.86730HepG2CKAP4
DGKZENSG00000149091.11379.36850258.980400.550701.938201.30310HepG2CNOT7
DGKZENSG00000149091.11692.131501154.14530-0.737708.587607.43380HepG2CPSF6
DGKZENSG00000149091.11234.79440377.63720-0.685603.522901.91500HepG2CSTF2T
DGKZENSG00000149091.11865.47800578.858700.580208.054307.06510HepG2CELF1
DGKZENSG00000149091.11554.58880406.212800.449102.986702.28500HepG2DDX21
DGKZENSG00000149091.11853.58860571.953600.577503.757803.03970HepG2DDX3X
DGKZENSG00000149091.11506.60420384.577500.397502.878202.16420HepG2DNAJC21
DGKZENSG00000149091.11615.04270381.208000.690009.891108.74870HepG2DNAJC2
DGKZENSG00000149091.11771.61220472.309700.708004.002303.29830HepG2EIF2S1
DGKZENSG00000149091.111183.55480879.749000.427904.236702.79950HepG2EIF2S2
DGKZENSG00000149091.11856.76120508.316100.753102.321901.68910HepG2EIF4B
DGKZENSG00000149091.111445.101101192.356200.277302.725902.12890HepG2ETF1
DGKZENSG00000149091.111540.897701171.013600.395902.816602.03860HepG2FIP1L1
DGKZENSG00000149091.11683.834501156.12890-0.757603.096902.02050HepG2FTO
DGKZENSG00000149091.11358.13900499.98310-0.481403.211502.36860HepG2FUBP3
DGKZENSG00000149091.11928.39750526.885800.817208.509807.35140HepG2FXR1
DGKZENSG00000149091.11539.57700357.222300.594902.922101.87420HepG2GNB2L1
DGKZENSG00000149091.11389.40880239.808600.699302.737201.63100HepG2GRSF1
DGKZENSG00000149091.11451.37700219.356801.041007.103904.84340HepG2HNRNPA0
DGKZENSG00000149091.11546.14220388.262200.492102.286301.69370HepG2HNRNPA1
DGKZENSG00000149091.11368.71770214.167000.783703.956402.26610HepG2HNRNPAB
DGKZENSG00000149091.11649.776301248.54170-0.9422012.8595011.63340HepG2HNRNPLL
DGKZENSG00000149091.11882.42280429.022701.0403022.9162021.30430HepG2HNRNPU
DGKZENSG00000149091.11839.19510496.544600.757007.181006.14370HepG2IGF2BP2
DGKZENSG00000149091.11569.94030438.231000.379003.571702.74850HepG2ILF2
DGKZENSG00000149091.11443.48620247.136400.843504.683703.07510HepG2KHDRBS1
DGKZENSG00000149091.11856.06630527.071400.699605.710504.78060HepG2MAGOH
DGKZENSG00000149091.111332.81000529.959801.3304020.1091018.53700HepG2MATR3
DGKZENSG00000149091.11786.270601273.36560-0.695504.547303.28220HepG2MTPAP
DGKZENSG00000149091.11893.82310542.393300.720606.357105.41310HepG2NCBP2
DGKZENSG00000149091.11949.23090460.558401.043304.178302.81600HepG2NONO
DGKZENSG00000149091.11770.737901107.07610-0.522404.697703.73210HepG2NSUN2
DGKZENSG00000149091.11739.39000513.562600.525706.152705.30250HepG2PCBP1
DGKZENSG00000149091.11598.93640397.884700.590002.314701.36280HepG2PCBP2
DGKZENSG00000149091.11541.18380382.652400.500004.381003.47390HepG2PPIL4
DGKZENSG00000149091.11569.66420786.93160-0.466105.128004.10930HepG2PRPF4
DGKZENSG00000149091.11876.17380522.601400.7454012.4300011.43570HepG2PTBP1
DGKZENSG00000149091.11962.80210589.084900.708709.027208.03430HepG2PUF60
DGKZENSG00000149091.111075.57070625.377800.7822019.3305018.04930HepG2PUM1
DGKZENSG00000149091.111038.17200791.789700.390804.896004.11860HepG2PUS1
DGKZENSG00000149091.111115.50280493.108101.177603.897601.71950HepG2RBM17
DGKZENSG00000149091.11689.74830996.58210-0.530906.442005.73090HepG2RBM22
DGKZENSG00000149091.11634.60620513.636100.305001.876901.31280HepG2RBM25
DGKZENSG00000149091.11867.40020422.217101.038609.881107.98540HepG2RBM27
DGKZENSG00000149091.11641.28320342.861400.903207.226605.52500HepG2RCC2
DGKZENSG00000149091.111069.73910581.578400.8791017.3345016.20250HepG2NELFE
DGKZENSG00000149091.11724.02370541.709900.418403.093602.44710HepG2RECQL
DGKZENSG00000149091.111034.11460428.795901.2699024.2257022.69610HepG2RPS19
DGKZENSG00000149091.11793.52520389.350201.027109.844608.41490HepG2RPS2
DGKZENSG00000149091.11539.79550260.405701.051608.013906.67290HepG2RPS3A
DGKZENSG00000149091.11587.83320397.491400.564402.582601.54730HepG2RPS5
DGKZENSG00000149091.11570.03140382.058500.577105.331704.49040HepG2SAFB2
DGKZENSG00000149091.11425.45400245.207600.794903.634502.14250HepG2SART3
DGKZENSG00000149091.11600.66080430.249300.481302.150901.31850HepG2SERBP1
DGKZENSG00000149091.111005.63500476.270101.078203.437601.88600HepG2SF1
DGKZENSG00000149091.111376.90000993.560500.470602.823402.14210HepG2SF3A3
DGKZENSG00000149091.11762.40880544.037700.486805.297204.52400HepG2SF3B4
DGKZENSG00000149091.11939.76360462.426301.023002.915301.41880HepG2SFPQ
DGKZENSG00000149091.11699.18810564.919100.307502.938202.21700HepG2SLBP
DGKZENSG00000149091.11763.75930445.536100.7775013.5645012.30720HepG2SMN1
DGKZENSG00000149091.11679.62080392.451400.792103.979902.81340HepG2SMNDC1
DGKZENSG00000149091.11932.17090425.902401.130004.074102.41000HepG2SNRNP200
DGKZENSG00000149091.11941.238001375.05180-0.546903.199802.35750HepG2SNRNP70
DGKZENSG00000149091.111288.74560581.681301.1476032.8696031.05320HepG2SRSF5
DGKZENSG00000149091.11444.75110226.644200.972506.520604.76920HepG2STIP1
DGKZENSG00000149091.111120.77400661.492700.760608.820607.81540HepG2SUCLG1
DGKZENSG00000149091.11359.42190510.49930-0.506203.773703.13560HepG2TAF15
DGKZENSG00000149091.111162.64840416.842801.4797038.7855037.31240HepG2TIAL1
DGKZENSG00000149091.11815.76840420.604400.9556018.9663017.66120HepG2TRIM56
DGKZENSG00000149091.11902.74190575.573400.649203.381702.40570HepG2TUFM
DGKZENSG00000149091.111368.708801001.743700.450203.937603.19330HepG2U2AF1
DGKZENSG00000149091.111690.91590495.080601.772008.418906.61340HepG2U2AF2
DGKZENSG00000149091.11944.21370609.276500.631903.761502.77900HepG2UBE2L3
DGKZENSG00000149091.11526.61230294.536300.838202.448901.73440HepG2UCHL5
DGKZENSG00000149091.11438.22510233.265500.909605.683204.11600HepG2XPO5
DGKZENSG00000149091.11688.62790422.235600.705603.341302.17280HepG2XRCC6
DGKZENSG00000149091.111261.54840969.080800.380405.878105.15880HepG2ZNF622
DGKZENSG00000149091.112801.717702073.909300.433908.899807.95720K562AGGF1
DGKZENSG00000149091.111178.816502261.67560-0.9401016.0037014.75010K562AQR
DGKZENSG00000149091.111305.47230947.526900.462206.551605.04780K562BCLAF1
DGKZENSG00000149091.112857.472102440.641300.227402.450401.41360K562CPEB4
DGKZENSG00000149091.111134.15640718.840600.657806.294504.60730K562CSTF2
DGKZENSG00000149091.112605.637703508.32190-0.429107.087805.54870K562CELF1
DGKZENSG00000149091.111516.021901251.233300.276802.282901.34130K562DDX3X
DGKZENSG00000149091.112722.346502322.173400.229302.575001.73460K562DKC1
DGKZENSG00000149091.111584.06130867.814600.868109.024907.29090K562EFTUD2
DGKZENSG00000149091.112766.214801839.700400.5883013.0405011.65760K562EIF2S2
DGKZENSG00000149091.111318.09200928.784500.504902.244101.32200K562EIF3D
DGKZENSG00000149091.11783.36970531.448200.559706.280605.09880K562EIF3G
DGKZENSG00000149091.11753.630101189.49790-0.658406.591204.71720K562FKBP4
DGKZENSG00000149091.111705.893001359.458800.327403.952803.24850K562FXR1
DGKZENSG00000149091.11118.06340396.28290-1.7470017.6269015.44250K562G3BP2
DGKZENSG00000149091.111803.470302175.34680-0.270502.923101.75140K562GLRX3
DGKZENSG00000149091.111277.44780752.490800.763403.609602.37840K562IGF2BP2
DGKZENSG00000149091.111717.832001221.312100.492105.883403.56020K562LSM11
DGKZENSG00000149091.111242.86980790.218400.653307.518106.10580K562MAGOH
DGKZENSG00000149091.111038.08200788.521100.396602.295601.46190K562MATR3
DGKZENSG00000149091.113307.954302565.579400.366604.349903.16050K562MBNL1
DGKZENSG00000149091.112299.572303040.79720-0.403104.476503.03680K562MSI2
DGKZENSG00000149091.111757.089102287.09330-0.380306.565005.36760K562MTPAP
DGKZENSG00000149091.111287.75660856.014600.589102.653701.39870K562NONO
DGKZENSG00000149091.111173.54610702.985600.739203.902902.73640K562PCBP2
DGKZENSG00000149091.111314.18860844.493200.637903.832902.95030K562PRPF8
DGKZENSG00000149091.111565.005501227.447300.350402.757401.85550K562PSIP1
DGKZENSG00000149091.111509.43460767.793000.9751020.3265018.60260K562PTBP1
DGKZENSG00000149091.112620.017203311.24110-0.337803.278502.11280K562PUM1
DGKZENSG00000149091.112971.430802140.157900.473302.988902.42900K562PUS1
DGKZENSG00000149091.112621.261802085.244700.329904.245003.52660K562RBM15
DGKZENSG00000149091.111578.965501120.284300.495005.866504.41840K562RCC2
DGKZENSG00000149091.111163.01180796.510600.546002.262201.36720K562RPS3
DGKZENSG00000149091.112049.520201500.419200.449802.397101.39370K562SAFB
DGKZENSG00000149091.112103.057002507.48170-0.253803.091802.23000K562SF3A3
DGKZENSG00000149091.11743.24010411.915700.8514011.9879010.12400K562SF3B4
DGKZENSG00000149091.111580.822901061.958400.573806.726304.92420K562SRFBP1
DGKZENSG00000149091.112278.221902568.96900-0.173302.155901.32070K562SRPK2
DGKZENSG00000149091.111182.91790752.762700.652007.690606.51860K562SRSF1
DGKZENSG00000149091.111234.35820768.772100.683008.772906.76020K562SRSF4
DGKZENSG00000149091.111169.84010711.099900.718105.211103.68730K562SRSF5
DGKZENSG00000149091.111557.723302093.47230-0.426504.087402.40850K562SSRP1
DGKZENSG00000149091.111484.55680761.695100.9626015.2855013.36330K562TARDBP
DGKZENSG00000149091.111448.98270734.780300.9796019.6827017.35700K562TIA1
DGKZENSG00000149091.111174.52690721.392900.703103.625302.34410K562TRA2A
DGKZENSG00000149091.111715.634901254.626300.451403.931302.76170K562TRIM56
DGKZENSG00000149091.112004.339902397.51260-0.258403.862702.87430K562WDR43
DGKZENSG00000149091.112168.025902679.32400-0.305502.929501.59650K562WRN
DGKZENSG00000149091.111279.29490881.312300.537503.000101.72230K562XRN2
DGKZENSG00000149091.111886.866802548.02230-0.433404.931903.72600K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DGKZ is not available on ENCORE database.





13 RBPs can affect the splicing of DGKZ :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDGKZENSG00000149091.11chr11+4638972746389853463895544638962946391043463911000.183000.000000.00010includedK562U2AF2
A3SSDGKZENSG00000149091.11chr11+4639805546398114463980734639811446397853463979470.117000.000000.00000longerK562AQR
A3SSDGKZENSG00000149091.11chr11+4639759946397695463976154639769546397400463975010.068000.000860.00608longerK562AQR
A3SSDGKZENSG00000149091.11chr11+4638952746389629463895544638962946389201463892970.181000.000800.00568longerK562AQR
A3SSDGKZENSG00000149091.11chr11+4639146546391559463914904639155946391043463911000.064000.007460.04105longerK562AQR
A3SSDGKZENSG00000149091.11chr11+4640044346400661464005404640066146400006464000500.228000.000840.00595longerK562AQR
RIDGKZENSG00000149091.11chr11+4640075246401118464007524640078646401018464011180.150000.001330.00958includedK562PUS1
RIDGKZENSG00000149091.11chr11+4640075246401118464007524640078646401018464011180.192000.000060.00124includedHepG2SF3A3
RIDGKZENSG00000149091.11chr11+4640075246401118464007524640078646401018464011180.323000.000340.00364includedHepG2U2AF2
RIDGKZENSG00000149091.11chr11+4640075246401118464007524640078646401018464011180.159000.000010.00452includedK562LARP7
RIDGKZENSG00000149091.11chr11+4640075246401118464007524640078646401018464011180.230000.000430.07756includedHepG2RBM15
RIDGKZENSG00000149091.11chr11+4640075246401118464007524640078646401018464011180.284000.005120.04701includedHepG2U2AF1
RIDGKZENSG00000149091.11chr11+4639615346396389463961534639621646396315463963890.131000.000000.00000includedHepG2RBM22
RIDGKZENSG00000149091.11chr11+4640075246401118464007524640078646401018464011180.095000.002530.03056includedK562UTP18
RIDGKZENSG00000149091.11chr11+4640075246401118464007524640078646401018464011180.249000.001600.01803includedK562EFTUD2
RIDGKZENSG00000149091.11chr11+4640075246401118464007524640078646401018464011180.250000.000010.00006includedK562AQR
RIDGKZENSG00000149091.11chr11+4640000646400661464000064640005046400540464006610.435000.000780.00539includedK562AQR
RIDGKZENSG00000149091.11chr11+464007524640111846400752464007864640101846401118-0.263000.000070.00945excludedHepG2SSB
MXEDGKZENSG00000149091.11chr11+46389527463896294639104346391100463892014638929746391490463915590.137000.000000.000061includedK562AQR
MXEDGKZENSG00000149091.11chr11+46389201463892974638955146389629463888404638894946391043463911000.332000.000130.007631includedHepG2HNRNPC
MXEDGKZENSG00000149091.11chr11+46389201463892974638955146389629463888404638894946391043463911000.331000.000030.002661includedHepG2TIAL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DGKZ is not avaliable on ENCORE database.