CSK

General Information

Gene Name       : CSK
Gene ID             : ENSG00000103653.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CSK)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CSKENSG00000103653.1625.0190.1057.55ENCSR000AEF
HepG2CSKENSG00000103653.1671.7332.3852.06ENCSR985KAT
K562CSKENSG00000103653.1653.6742.4048.03ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CSK is not avaliable on ENCORE database.



Proteins bound to RNA
  • CSK RNA is bound by 20 proteins.  







eCLIP assay for CSK is not avaliable on ENCORE database.





20 proteins are bound to CSK RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr157509497275095035+3'-UTR3.622014.92926HepG2LARP4
chr157509525175095321+3'-UTR4.042776.86497HepG2UPF1
chr157509517075095251+3'-UTR3.095145.09741K562UPF1
chr157509126575091328+3'-UTR,CDS,intron-Proximal4.903995.68502HepG2PRPF8
chr157509533675095385+3'-UTR3.782974.36276HepG2LARP4
chr157509532575095461+3'-UTR3.662377.16367HepG2AKAP1
chr157509531975095436+3'-UTR4.8485717.15810HepG2DDX55
chr157509532175095472+3'-UTR4.5277410.56484HepG2UPF1
chr157509524375095319+3'-UTR3.211788.86044HepG2DDX55
chr157509491575095067+3'-UTR4.3109411.42766HepG2UPF1
chr157509532375095384+3'-UTR3.8205911.42779K562PABPC4
chr157509496975095018+3'-UTR3.972053.33617HepG2PABPN1
chr157509531675095382+3'-UTR3.113823.87462HepG2PCBP2
chr157509538475095434+3'-UTR4.141605.37920K562PABPC4
chr157507493675074987+5'-UTR,intron-Proximal5.9961531.33910HepG2PCBP2
chr157507482975074895+5'-UTR,intron-Distal4.6389728.49576HepG2PCBP2
chr157507454175074610+5'-UTR,intron-Distal,intron-Proximal5.423174.97000K562DDX3X
chr157507493075075036+5'-UTR,intron-Proximal5.4922911.95366HepG2HNRNPK
chr157507484775074890+5'-UTR,intron-Distal3.762207.34495HepG2DDX59
chr157507462175074693+5'-UTR,intron-Distal3.729695.23852K562DDX3X
chr157507490875074985+5'-UTR,intron-Distal,intron-Proximal4.2206815.69024HepG2DDX59
chr157507492475075029+5'-UTR,intron-Proximal4.2505016.97960K562PCBP1
chr157507498775075043+5'-UTR,intron-Proximal4.6265311.56505HepG2PCBP2
chr157507488775075025+5'-UTR,intron-Distal,intron-Proximal3.821285.47244HepG2LARP4
chr157507455175074607+5'-UTR,intron-Distal,intron-Proximal3.842237.91814HepG2DDX3X
chr157507489575074936+5'-UTR,intron-Distal,intron-Proximal5.1651825.82804HepG2PCBP2
chr157507484975074930+5'-UTR,intron-Distal,intron-Proximal3.911109.27417HepG2HNRNPK
chr157507484475074924+5'-UTR,intron-Distal,intron-Proximal5.2820014.97869K562PCBP1
chr157507462675074719+5'-UTR,intron-Distal4.7341231.94504HepG2DDX3X
chr157507498575075026+5'-UTR,intron-Proximal3.508726.74466HepG2DDX59
chr157507443675074530+5'-UTR,intron-Proximal3.518644.85956HepG2NCBP2
chr157507446675074527+5'-UTR,intron-Proximal4.190239.23400HepG2DDX3X
chr157507443575074526+5'-UTR,intron-Proximal3.060994.97367K562DDX3X
chr157509415575094234+CDS,intron-Proximal4.147447.72847HepG2PPIG
chr157509442275094483+CDS,intron-Proximal4.938587.02967HepG2PRPF8
chr157509462175094685+CDS,intron-Proximal3.770686.39986K562SF3B4
chr157509338875093444+CDS,intron-Proximal3.656304.77136HepG2PPIG
chr157509307875093136+CDS,intron-Proximal4.250728.78209HepG2PRPF8
chr157509064675090661+CDS,intron-Distal,intron-Proximal3.578507.85990HepG2PRPF8
chr157509386275093933+CDS,intron-Proximal3.192758.07998HepG2PPIG
chr157509343675093485+CDS,intron-Proximal4.193095.93840HepG2PRPF8
chr157509403875094155+CDS3.8636811.74630HepG2PPIG
chr157509461575094740+CDS,intron-Proximal3.076825.66342HepG2BUD13
chr157509403875094137+CDS4.042293.56019HepG2GRWD1
chr157509182475091872+CDS,intron-Proximal4.933746.69228HepG2PRPF8
chr157509141075091517+intron-Distal,intron-Proximal5.174779.99483K562EFTUD2
chr157509137475091489+intron-Distal,intron-Proximal3.136443.94332HepG2FAM120A
chr157509137975091513+intron-Distal4.0848215.43022HepG2EFTUD2
chr157509142775091520+intron-Distal,intron-Proximal3.308435.83656K562PRPF8
chr157509066175090696+intron-Distal,intron-Proximal4.632109.76577HepG2PRPF8
chr157509136975091511+intron-Distal,intron-Proximal3.835745.18989HepG2PRPF4
chr157509423275094272+intron-Proximal4.864994.35676HepG2PRPF8
chr157509459975094672+intron-Proximal3.703814.52919HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CSK is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CSK is not available on ENCORE database.

  • 81 RBPs can affect the levels of CSK.  








The Knockdown/knockout RNA-Seq assay for CSK is not available on ENCORE database.





81 RBPs can affect the gene expression of CSK :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CSKENSG00000103653.12414.09800627.12760-0.598804.865103.87890HepG2CALR
CSKENSG00000103653.12831.075401163.11700-0.484903.034902.01150HepG2CCAR1
CSKENSG00000103653.12563.31460879.79620-0.643206.120105.13080HepG2CPSF6
CSKENSG00000103653.121126.13370874.466700.364802.848602.19790HepG2CELF1
CSKENSG00000103653.121208.97900940.437900.362303.149002.36600HepG2DAZAP1
CSKENSG00000103653.12408.65210560.95170-0.457002.145001.35140HepG2DDX24
CSKENSG00000103653.12758.342201006.75300-0.408804.681403.84200HepG2DKC1
CSKENSG00000103653.12366.79830527.80600-0.525002.763701.65710HepG2AGO1
CSKENSG00000103653.121136.25020888.657700.354502.319701.57050HepG2EIF4G2
CSKENSG00000103653.121439.33730995.696100.531502.853102.15040HepG2FXR1
CSKENSG00000103653.12464.80390997.24830-1.1013012.8714011.58640HepG2GPKOW
CSKENSG00000103653.12571.21110951.69870-0.736507.570606.58720HepG2HNRNPLL
CSKENSG00000103653.12728.34970559.945100.379202.181201.63620HepG2HNRNPU
CSKENSG00000103653.12522.77070961.89720-0.8797020.3637017.94820HepG2KIF1C
CSKENSG00000103653.121671.659401228.583500.444202.820401.98320HepG2LARP4
CSKENSG00000103653.121360.791901001.498400.442201.879601.35460HepG2MATR3
CSKENSG00000103653.12662.84410970.76020-0.550402.873001.88460HepG2MTPAP
CSKENSG00000103653.12625.21370818.66010-0.388902.807201.58410HepG2NAA15
CSKENSG00000103653.12613.26360843.91320-0.460603.348802.52570HepG2NSUN2
CSKENSG00000103653.12716.61130499.419000.520802.058201.41420HepG2PPIL4
CSKENSG00000103653.12613.04700821.00280-0.421404.336403.39220HepG2PRPF4
CSKENSG00000103653.121399.69820944.857800.5668011.6572010.61620HepG2PUM1
CSKENSG00000103653.12628.954401071.83050-0.7690016.2067014.93560HepG2PUS1
CSKENSG00000103653.12926.714101115.34500-0.267302.217301.72220HepG2NELFE
CSKENSG00000103653.12698.29050536.555700.380002.553501.96090HepG2RPS19
CSKENSG00000103653.12875.00900647.797600.433702.612501.83340HepG2RPS2
CSKENSG00000103653.12829.50540498.631200.734208.894507.84040HepG2SAFB2
CSKENSG00000103653.121419.845701077.305800.398202.262801.65240HepG2SF3A3
CSKENSG00000103653.12981.11210581.446600.754706.534405.61180HepG2SMN1
CSKENSG00000103653.12376.499001048.10310-1.4771016.5016014.61960HepG2SNRNP70
CSKENSG00000103653.121307.970901683.02700-0.363705.554104.91170HepG2SRFBP1
CSKENSG00000103653.12819.723601089.07520-0.409904.642204.06930HepG2SRSF1
CSKENSG00000103653.121254.62460878.808000.513507.548106.58230HepG2SRSF5
CSKENSG00000103653.121110.614101461.21840-0.395805.977105.27830HepG2SSB
CSKENSG00000103653.121394.92390999.504000.480804.632603.86480HepG2SUCLG1
CSKENSG00000103653.12366.51420979.03760-1.4175027.5184025.98650HepG2TAF15
CSKENSG00000103653.12724.85160899.45960-0.311402.251401.49540HepG2TIA1
CSKENSG00000103653.12830.16600548.965300.596605.416504.67840HepG2TRIM56
CSKENSG00000103653.121116.28190869.529300.360302.427901.61330HepG2TUFM
CSKENSG00000103653.121266.26660922.404900.457006.851905.98060HepG2UTP3
CSKENSG00000103653.12621.02720810.23210-0.383704.223103.42080HepG2ZC3H8
CSKENSG00000103653.121165.315101493.58830-0.358102.781401.55550K562ABCF1
CSKENSG00000103653.12819.185401084.40000-0.404603.441002.71060K562AKAP8L
CSKENSG00000103653.122601.991701978.737400.394904.031102.48670K562APOBEC3C
CSKENSG00000103653.121415.724701901.33940-0.425501.931701.42510K562AQR
CSKENSG00000103653.121110.453801777.75640-0.678902.397301.42000K562CNOT7
CSKENSG00000103653.122179.859402757.32710-0.339003.971802.79200K562CELF1
CSKENSG00000103653.121980.417601630.258000.280603.559902.83320K562DDX47
CSKENSG00000103653.12727.55830337.298801.1089018.5642016.43720K562EIF3G
CSKENSG00000103653.121114.41040745.498800.579906.238705.01640K562EIF4A3
CSKENSG00000103653.12791.209501141.36990-0.528603.542801.66010K562ESF1
CSKENSG00000103653.12285.20170777.67870-1.4472021.2516018.06520K562FKBP4
CSKENSG00000103653.12498.75890793.33500-0.669603.082002.17480K562FMR1
CSKENSG00000103653.121657.12080775.283701.0958031.8095029.89070K562FXR1
CSKENSG00000103653.1234.94140214.43030-2.6175021.2239018.70770K562G3BP2
CSKENSG00000103653.12956.416501447.41580-0.597809.726807.70710K562GLRX3
CSKENSG00000103653.12435.57340744.57910-0.773503.504402.61460K562GPKOW
CSKENSG00000103653.121779.550302266.19620-0.348803.356802.52700K562GRSF1
CSKENSG00000103653.12527.77090895.80360-0.763309.344708.29900K562HNRNPC
CSKENSG00000103653.121133.56270882.942700.360402.179001.35630K562HNRNPM
CSKENSG00000103653.12814.314801150.88030-0.499104.761503.62670K562KIF1C
CSKENSG00000103653.12366.62660635.65810-0.793904.043502.89610K562KRR1
CSKENSG00000103653.121121.26540536.880701.0624015.2966013.20020K562MAGOH
CSKENSG00000103653.12860.66400535.710300.683905.638404.26040K562MATR3
CSKENSG00000103653.121552.424701289.268200.267902.174901.38500K562MBNL1
CSKENSG00000103653.121580.458602390.27820-0.596807.874006.02260K562MSI2
CSKENSG00000103653.121063.699601521.77280-0.516709.119307.73660K562MTPAP
CSKENSG00000103653.121244.753401690.80420-0.441809.422208.15570K562NSUN2
CSKENSG00000103653.12648.21980477.593400.440602.167401.30560K562PCBP2
CSKENSG00000103653.12799.804501409.24000-0.817209.759708.20190K562PCBP3
CSKENSG00000103653.12793.585901080.89060-0.445804.457803.43920K562POLR2G
CSKENSG00000103653.12950.66770521.653100.865809.593508.41190K562PTBP1
CSKENSG00000103653.122141.195502549.91940-0.252002.759501.80180K562PUM2
CSKENSG00000103653.12610.759501075.55160-0.8164010.261209.26080K562PUS1
CSKENSG00000103653.12820.043201047.85990-0.353703.302402.66350K562RBM15
CSKENSG00000103653.12834.04580499.911300.738404.690603.56110K562RBM22
CSKENSG00000103653.12599.85560311.765900.944105.940704.40880K562RPS3
CSKENSG00000103653.121250.233901668.42510-0.416305.243404.14630K562SF3A3
CSKENSG00000103653.12400.87520222.929400.846508.140106.63060K562SF3B4
CSKENSG00000103653.12879.18590511.453900.781505.165904.20420K562SRSF1
CSKENSG00000103653.12439.16150300.994100.544903.368802.19230K562SRSF4
CSKENSG00000103653.121077.892901408.63370-0.386103.021201.59130K562SSRP1
CSKENSG00000103653.12837.586001288.43180-0.621306.216304.26440K562STAU1
CSKENSG00000103653.121550.058201084.223000.515602.833502.00280K562SYNCRIP
CSKENSG00000103653.1269.72800210.48530-1.593907.692804.68210K562TAF15
CSKENSG00000103653.12941.43850517.495600.863204.326803.43450K562TARDBP
CSKENSG00000103653.12814.30590499.216800.705804.447403.37310K562TIA1
CSKENSG00000103653.12814.88660490.186000.733204.355302.93150K562TRA2A
CSKENSG00000103653.121746.015002190.73610-0.327304.257602.68250K562TROVE2
CSKENSG00000103653.12103.09240214.63440-1.057907.040805.76910K562U2AF2
CSKENSG00000103653.122253.194902758.64310-0.292002.947501.49520K562UBE2L3
CSKENSG00000103653.121392.920601792.79730-0.364105.603604.62000K562UPF1
CSKENSG00000103653.12984.211201534.03720-0.640309.245807.60400K562WDR3
CSKENSG00000103653.121262.147702142.24730-0.763205.520604.23350K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CSK is not available on ENCORE database.





18 RBPs can affect the splicing of CSK :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECSKENSG00000103653.12chr15+7507678375076864750750087507506175090573750906530.439000.001390.02931includedK562U2AF1
A5SSCSKENSG00000103653.12chr15+7509055275090776750905527509065375090955750910690.059000.000040.00752longerHepG2RBM22
RICSKENSG00000103653.12chr15+7509403575094424750940357509423175094337750944240.122000.000230.00193includedK562PUS1
RICSKENSG00000103653.12chr15+7509275275093087750927527509284675093021750930870.182000.000000.00000includedK562PUS1
RICSKENSG00000103653.12chr15+7509302175093263750930217509308775093163750932630.175000.000000.00016includedHepG2SF3A3
RICSKENSG00000103653.12chr15+7509275275093087750927527509284675093021750930870.067000.000000.00000includedHepG2SF3A3
RICSKENSG00000103653.12chr15+7509275275093087750927527509284675093021750930870.105000.000000.00052includedK562SF3B1
RICSKENSG00000103653.12chr15+7509275275093087750927527509284675093021750930870.123000.000000.00000includedHepG2U2AF2
RICSKENSG00000103653.12chr15+7509302175093263750930217509308775093163750932630.051000.011160.09673includedHepG2PRPF8
RICSKENSG00000103653.12chr15+7509275275093087750927527509284675093021750930870.127000.000130.02476includedHepG2DROSHA
RICSKENSG00000103653.12chr15+7509302175093263750930217509308775093163750932630.074000.004090.04361includedK562AGGF1
RICSKENSG00000103653.12chr15+7509302175093263750930217509308775093163750932630.081000.000110.00226includedK562PRPF8
RICSKENSG00000103653.12chr15+7509403575094424750940357509423175094337750944240.054000.007240.07273includedK562PRPF8
RICSKENSG00000103653.12chr15+7509403575094424750940357509423175094337750944240.078000.002860.05370includedK562RBM22
RICSKENSG00000103653.12chr15+7509302175093263750930217509308775093163750932630.192000.000010.00129includedK562BUD13
RICSKENSG00000103653.12chr15+7509302175093263750930217509308775093163750932630.064000.009320.07284includedK562AKAP8L
RICSKENSG00000103653.12chr15+7509275275093087750927527509284675093021750930870.088000.000000.00001includedK562AKAP8L
RICSKENSG00000103653.12chr15+7509275275093087750927527509284675093021750930870.055000.001110.01302includedHepG2TAF15
RICSKENSG00000103653.12chr15+7509275275093087750927527509284675093021750930870.053000.001030.01190includedHepG2U2AF1
RICSKENSG00000103653.12chr15+7509302175093263750930217509308775093163750932630.111000.006380.06904includedK562U2AF2
RICSKENSG00000103653.12chr15+7509302175093263750930217509308775093163750932630.118000.000970.01979includedHepG2TIAL1
RICSKENSG00000103653.12chr15+7509275275093087750927527509284675093021750930870.091000.000020.00248includedK562CPSF6
RICSKENSG00000103653.12chr15+7509275275093087750927527509284675093021750930870.052000.000650.00648includedHepG2SF3B4
RICSKENSG00000103653.12chr15+7509302175093263750930217509308775093163750932630.058000.001400.01646includedHepG2RBM22
RICSKENSG00000103653.12chr15+7509302175093263750930217509308775093163750932630.070000.009360.08356includedK562UTP18
RICSKENSG00000103653.12chr15+7509275275093087750927527509284675093021750930870.089000.000000.00004includedK562UTP18
RICSKENSG00000103653.12chr15+7509302175093263750930217509308775093163750932630.057000.001860.02035includedK562EFTUD2
RICSKENSG00000103653.12chr15+7509403575094424750940357509423175094337750944240.057000.005430.04962includedK562EFTUD2
RICSKENSG00000103653.12chr15+7509302175093263750930217509308775093163750932630.298000.000000.00000includedK562AQR
RICSKENSG00000103653.12chr15+7509403575094424750940357509423175094337750944240.245000.000000.00000includedK562AQR
RICSKENSG00000103653.12chr15+7509275275093087750927527509284675093021750930870.167000.000000.00000includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CSK is not avaliable on ENCORE database.