BUB3

General Information

Gene Name       : BUB3
Gene ID             : ENSG00000154473.17
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: BUB3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878BUB3ENSG00000154473.17144.08212.08178.08ENCSR000AEF
HepG2BUB3ENSG00000154473.17208.44138.87173.66ENCSR985KAT
K562BUB3ENSG00000154473.17194.02151.26172.64ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for BUB3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • BUB3 RNA is bound by 30 proteins.  







eCLIP assay for BUB3 is not avaliable on ENCORE database.





30 proteins are bound to BUB3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr10124924724124924854+3'-UTR3.162309.04606K562TIA1
chr10124923658124923675+3'-UTR,intron-Distal4.4060332.43217K562PUM2
chr10124924499124924603+3'-UTR,CDS,intron-Proximal3.4132618.52637K562FAM120A
chr10124924824124924865+3'-UTR4.8091110.68247K562PABPC4
chr10124924821124924870+3'-UTR6.89877400.00000K562PUM2
chr10124924712124924794+3'-UTR3.5153711.18847HepG2SUB1
chr10124923634124923712+3'-UTR,intron-Distal3.292354.03249HepG2FUBP3
chr10124924388124924430+3'-UTR,intron-Distal3.073823.37563HepG2FUBP3
chr10124923302124923373+3'-UTR,CDS,intron-Distal,intron-Proximal3.338185.40388HepG2U2AF2
chr10124923616124923658+3'-UTR,intron-Distal4.1846937.16181K562PUM2
chr10124923860124923945+3'-UTR,intron-Distal3.126197.81017K562UPF1
chr10124924548124924604+3'-UTR,CDS,intron-Proximal3.3062314.92104K562UPF1
chr10124923675124923735+3'-UTR,intron-Distal4.0572654.67636K562PUM2
chr10124924793124924821+3'-UTR4.9534465.99516K562PUM2
chr10124923831124923972+3'-UTR,intron-Distal3.205726.79753K562IGF2BP1
chr10124924761124924862+3'-UTR3.370446.35758K562ZC3H11A
chr10124924713124924793+3'-UTR3.97127400.00000K562PUM2
chr10124924662124924712+3'-UTR4.083715.47880HepG2SUB1
chr10124924552124924601+3'-UTR,CDS,intron-Proximal3.747053.00614K562U2AF2
chr10124913921124913966+5'-UTR3.4543814.76558K562DDX3X
chr10124914000124914043+5'-UTR,intron-Proximal4.535847.50107K562AQR
chr10124913966124914004+5'-UTR,intron-Proximal4.1174928.08890K562DDX3X
chr10124913976124914003+5'-UTR,intron-Proximal3.311727.80035K562UCHL5
chr10124913974124914005+5'-UTR,intron-Proximal4.428505.79396K562DDX24
chr10124914432124914458+5'-UTR,CDS,intron-Distal,intron-Proximal3.331786.80450K562UCHL5
chr10124913916124913972+5'-UTR3.929048.37300HepG2NCBP2
chr10124915210124915243+5'-UTR,CDS4.869845.56813HepG2PPIG
chr10124917245124917304+CDS3.367283.93112K562RBM15
chr10124922082124922148+CDS,intron-Distal,intron-Proximal3.633847.62845K562SF3B4
chr10124914433124914453+CDS,intron-Distal,intron-Proximal3.6590116.14308K562DDX3X
chr10124914627124914649+CDS,intron-Distal,intron-Proximal3.8559611.47097K562AQR
chr10124922182124922252+CDS,intron-Distal3.050895.27152HepG2BCLAF1
chr10124917251124917350+CDS3.044825.49645K562GRWD1
chr10124922138124922196+CDS,intron-Distal3.7381146.74598K562PUM2
chr10124915241124915326+CDS,intron-Proximal3.8360415.55931K562AQR
chr10124917241124917304+CDS,intron-Proximal3.076779.26797K562BUD13
chr10124922173124922220+CDS,intron-Distal4.304619.67189K562RPS3
chr10124922339124922402+CDS,intron-Distal,intron-Proximal3.6240410.50879K562PRPF8
chr10124922127124922150+CDS,intron-Distal,intron-Proximal3.477556.60490HepG2BCLAF1
chr10124914552124914570+CDS,intron-Distal3.2448510.23502K562YBX3
chr10124922258124922349+CDS,intron-Distal,intron-Proximal3.171097.16955HepG2GRWD1
chr10124919981124920035+CDS,intron-Distal3.279684.56061K562BUD13
chr10124914433124914474+CDS,intron-Distal,intron-Proximal3.668496.15459HepG2GRWD1
chr10124917243124917347+CDS,intron-Proximal4.2113215.80856HepG2PPIG
chr10124921777124921845+CDS,intron-Distal3.037905.87389HepG2G3BP1
chr10124921875124921931+CDS,intron-Distal,intron-Proximal6.1893714.34960K562IGF2BP1
chr10124922127124922150+CDS,intron-Distal,intron-Proximal5.764649.41982K562IGF2BP1
chr10124917306124917364+CDS3.756035.60176HepG2SUB1
chr10124919935124919978+CDS,intron-Distal3.859825.36555HepG2BCLAF1
chr10124922343124922352+CDS,intron-Distal,intron-Proximal3.514315.28960K562AQR
chr10124919922124920031+CDS,intron-Distal,intron-Proximal3.952946.49445HepG2G3BP1
chr10124921873124921930+CDS,intron-Distal,intron-Proximal3.310058.50351HepG2BCLAF1
chr10124919922124920016+CDS,intron-Distal,intron-Proximal3.104528.13987K562DDX24
chr10124914171124914286+intron-Distal5.197259.72546K562RBFOX2
chr10124922352124922393+intron-Distal,intron-Proximal3.895798.13013K562AQR
chr10124914197124914278+intron-Distal3.1963610.44325K562BUD13
chr10124914181124914289+intron-Distal3.761294.77128HepG2RBFOX2
chr10124922403124922502+intron-Distal,intron-Proximal3.2286014.35097K562KHSRP
chr10124922402124922537+intron-Distal,intron-Proximal3.9773620.56870K562PRPF8
chr10124922502124922558+intron-Distal3.333136.24191K562KHSRP
chr10124914202124914267+intron-Distal4.006565.12007K562DDX42
chr10124914123124914165+intron-Distal4.601914.67744K562BUD13
chr10124922371124922455+intron-Distal,intron-Proximal3.619887.57937K562RBM22
chr10124923272124923324+intron-Distal,intron-Proximal5.5605610.17728HepG2SF3B4
chr10124923272124923327+intron-Distal,intron-Proximal3.730168.87150K562SF3B4
chr10124923002124923054+intron-Distal3.637965.59440HepG2HNRNPK
chr10124914217124914328+intron-Distal4.4628313.55026K562PRPF8
chr10124914649124914678+intron-Distal,intron-Proximal5.3311515.34985K562AQR
chr10124914210124914299+intron-Distal3.323769.05128HepG2PRPF8
chr10124917426124917483+intron-Proximal3.487207.07647K562PRPF8
chr10124917414124917482+intron-Proximal3.159297.50863K562KHSRP
chr10124915273124915292+intron-Proximal3.193514.13575K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for BUB3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for BUB3 is not available on ENCORE database.

  • 98 RBPs can affect the levels of BUB3.  








The Knockdown/knockout RNA-Seq assay for BUB3 is not available on ENCORE database.





98 RBPs can affect the gene expression of BUB3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
BUB3ENSG00000154473.132675.456302301.921700.216802.944002.31940HepG2ACO1
BUB3ENSG00000154473.131798.231702856.47920-0.667708.295006.98100HepG2ASCC1
BUB3ENSG00000154473.132554.404903464.84460-0.439809.376708.23600HepG2AUH
BUB3ENSG00000154473.131062.468501425.62140-0.424203.821903.13020HepG2BOP1
BUB3ENSG00000154473.132148.625602901.77480-0.433502.944301.93700HepG2CCAR1
BUB3ENSG00000154473.131671.145802301.61520-0.4618011.1954010.03850HepG2CKAP4
BUB3ENSG00000154473.131065.781301308.80000-0.296301.948901.36080HepG2CPSF6
BUB3ENSG00000154473.131331.913401938.66970-0.541606.977605.29550HepG2CPSF7
BUB3ENSG00000154473.131023.764901371.50760-0.421903.610502.39620HepG2CSTF2
BUB3ENSG00000154473.132935.584403487.84720-0.248704.759603.82770HepG2DAZAP1
BUB3ENSG00000154473.132213.523703307.04510-0.579206.368605.45830HepG2DDX3X
BUB3ENSG00000154473.131561.952602840.75110-0.8629011.114709.97440HepG2DDX6
BUB3ENSG00000154473.131842.111802181.19410-0.243802.609101.92170HepG2DNAJC21
BUB3ENSG00000154473.131694.811402161.80090-0.351106.854805.89430HepG2DNAJC2
BUB3ENSG00000154473.131659.186502730.95150-0.718909.313908.26590HepG2EIF2S1
BUB3ENSG00000154473.132429.349903018.05560-0.313001.942801.40320HepG2EIF4A3
BUB3ENSG00000154473.131446.262102938.43740-1.0227012.1626010.77430HepG2EIF4B
BUB3ENSG00000154473.132253.302403440.78440-0.6107017.8056016.07340HepG2EIF4G1
BUB3ENSG00000154473.132545.376403296.08550-0.372903.673302.74280HepG2EIF4G2
BUB3ENSG00000154473.132639.580603978.11000-0.5918016.2238014.96640HepG2ETF1
BUB3ENSG00000154473.131602.814402824.72870-0.8175010.870409.59390HepG2G3BP1
BUB3ENSG00000154473.131133.490401512.86080-0.416503.589202.55590HepG2GEMIN5
BUB3ENSG00000154473.131095.885401483.63210-0.437003.191202.50860HepG2GPKOW
BUB3ENSG00000154473.131402.612902202.08910-0.650809.726608.62390HepG2HNRNPA1
BUB3ENSG00000154473.132566.566803205.32460-0.320605.293804.07340HepG2HNRNPA2B1
BUB3ENSG00000154473.131961.121602449.37290-0.320702.870302.16550HepG2HNRNPC
BUB3ENSG00000154473.131828.346502337.01590-0.354105.451504.48590HepG2HNRNPF
BUB3ENSG00000154473.132282.333202860.17050-0.325602.747202.05270HepG2HNRNPK
BUB3ENSG00000154473.132724.087103177.22910-0.222003.888103.09830HepG2HNRNPL
BUB3ENSG00000154473.131425.821402433.18240-0.7711019.9240018.41110HepG2HNRNPU
BUB3ENSG00000154473.131873.462602301.29980-0.296702.951602.20580HepG2IGF2BP1
BUB3ENSG00000154473.132109.107002485.42280-0.236904.024503.15780HepG2ILF2
BUB3ENSG00000154473.131872.411702482.46400-0.406902.697501.52320HepG2KHDRBS1
BUB3ENSG00000154473.132033.295403063.22390-0.591205.079403.94030HepG2LARP4
BUB3ENSG00000154473.132406.423803046.05390-0.340102.503201.87800HepG2MAGOH
BUB3ENSG00000154473.131916.481203135.28550-0.710108.742007.64920HepG2NCBP2
BUB3ENSG00000154473.132816.525803458.53020-0.296203.741602.85220HepG2NOL12
BUB3ENSG00000154473.131193.820301565.23410-0.390803.377301.60380HepG2NUP35
BUB3ENSG00000154473.132104.252802792.23710-0.408103.373702.58180HepG2PABPC4
BUB3ENSG00000154473.131995.727702408.48910-0.271203.591802.63880HepG2PARN
BUB3ENSG00000154473.131912.783002741.86760-0.5195012.2105011.08140HepG2PCBP1
BUB3ENSG00000154473.131135.269501405.15500-0.307702.844801.59630HepG2PKM
BUB3ENSG00000154473.131733.817402170.21200-0.323904.092503.21410HepG2PPIL4
BUB3ENSG00000154473.131240.009601548.70290-0.320703.908003.00410HepG2PRPF4
BUB3ENSG00000154473.132515.396703301.40820-0.392304.684603.93270HepG2PUF60
BUB3ENSG00000154473.132351.639803502.00340-0.5745011.188509.88770HepG2PUM2
BUB3ENSG00000154473.132568.976603021.59050-0.234102.422901.83210HepG2QKI
BUB3ENSG00000154473.131865.718602429.24940-0.380804.706303.62360HepG2RBM15
BUB3ENSG00000154473.132611.621903324.96280-0.348405.330904.67020HepG2RBM22
BUB3ENSG00000154473.132459.964503104.94880-0.335905.707604.97430HepG2NELFE
BUB3ENSG00000154473.132318.972402891.83390-0.318505.204104.39330HepG2RECQL
BUB3ENSG00000154473.131940.470402517.44360-0.375603.604202.84200HepG2RPLP0
BUB3ENSG00000154473.13976.316401653.37480-0.7600012.6084011.41070HepG2RPS19
BUB3ENSG00000154473.131626.817302340.41920-0.524705.498604.39360HepG2RPS2
BUB3ENSG00000154473.131345.214702615.97300-0.9595011.059609.50260HepG2RPS3A
BUB3ENSG00000154473.131182.103401659.36780-0.489304.593703.39820HepG2SERBP1
BUB3ENSG00000154473.132174.535802904.70290-0.417708.352207.41090HepG2SF3B4
BUB3ENSG00000154473.132641.956703165.38760-0.260804.858503.96860HepG2SLBP
BUB3ENSG00000154473.132006.870602526.99480-0.332507.165906.20660HepG2SMN1
BUB3ENSG00000154473.132683.995603259.57320-0.280304.506403.74170HepG2SRSF5
BUB3ENSG00000154473.131854.621502296.01890-0.308004.286303.44830HepG2SRSF7
BUB3ENSG00000154473.131462.462202466.59350-0.7541024.7228023.38210HepG2SRSF9
BUB3ENSG00000154473.132545.661903260.59190-0.357107.008306.26360HepG2SSB
BUB3ENSG00000154473.132153.382903707.10680-0.7837035.4436033.64730HepG2SUCLG1
BUB3ENSG00000154473.131057.202901380.00810-0.384403.082902.32300HepG2TARDBP
BUB3ENSG00000154473.131406.715002364.45640-0.7492016.2215015.19300HepG2TIAL1
BUB3ENSG00000154473.131546.654402385.41580-0.6251016.4747015.25200HepG2TRIM56
BUB3ENSG00000154473.132418.168103225.21810-0.415505.509004.22540HepG2TUFM
BUB3ENSG00000154473.131301.952001800.32880-0.467608.866607.73570HepG2UPF1
BUB3ENSG00000154473.131339.641201990.01810-0.570903.841202.64530HepG2UPF2
BUB3ENSG00000154473.131273.975701850.45250-0.5385010.134608.28330HepG2UTP18
BUB3ENSG00000154473.131525.069201738.13980-0.188701.872401.35910HepG2UTP3
BUB3ENSG00000154473.131705.944502139.29220-0.326602.276501.61320HepG2XRN2
BUB3ENSG00000154473.131691.853401980.01070-0.226903.156002.58400HepG2ZNF622
BUB3ENSG00000154473.137563.384004484.579700.7540033.6719031.76220K562AGGF1
BUB3ENSG00000154473.135886.618404927.779600.256402.204801.33830K562AKAP8
BUB3ENSG00000154473.136721.859904666.384900.526507.833906.68110K562AKAP8L
BUB3ENSG00000154473.135751.564704896.116700.232202.767401.85390K562ATP5C1
BUB3ENSG00000154473.133187.779703637.74610-0.190502.487601.58060K562BCLAF1
BUB3ENSG00000154473.131346.976901835.50920-0.446504.293902.92170K562CCAR1
BUB3ENSG00000154473.132905.402503514.48940-0.274602.539001.54250K562DDX3X
BUB3ENSG00000154473.134134.984004740.02900-0.197002.473601.85260K562DDX47
BUB3ENSG00000154473.135930.688705021.511900.240003.181702.23450K562DKC1
BUB3ENSG00000154473.131381.504601867.07980-0.434502.238401.34560K562EIF3A
BUB3ENSG00000154473.132210.877203671.89980-0.7319011.8000010.06970K562EIF4A3
BUB3ENSG00000154473.134228.341703345.309500.337901.910501.33540K562G3BP2
BUB3ENSG00000154473.131769.662902302.02480-0.379403.798102.87400K562GPKOW
BUB3ENSG00000154473.134833.099005876.96040-0.282102.889502.11870K562GRSF1
BUB3ENSG00000154473.131899.696703529.29370-0.8936021.2577019.68060K562HNRNPC
BUB3ENSG00000154473.132507.389603151.77870-0.330003.304802.04810K562HNRNPF
BUB3ENSG00000154473.133889.316104723.70470-0.280403.754502.71170K562HNRNPU
BUB3ENSG00000154473.137169.108304952.283100.533603.706902.73300K562KIF1C
BUB3ENSG00000154473.131438.080001965.65910-0.450903.057002.07080K562KRR1
BUB3ENSG00000154473.132981.988004293.53560-0.525907.960706.50460K562MAGOH
BUB3ENSG00000154473.135812.720204740.486700.294102.507201.50000K562MAK16
BUB3ENSG00000154473.136025.484803888.596300.631704.578803.35430K562NAA15
BUB3ENSG00000154473.135728.791903403.427200.751104.046702.79170K562PABPN1
BUB3ENSG00000154473.132782.896003445.77490-0.308202.850501.40250K562PHF6
BUB3ENSG00000154473.132287.776202695.05220-0.236402.067801.37630K562POLR2G
BUB3ENSG00000154473.132300.259903164.41350-0.460105.204003.91050K562PSIP1
BUB3ENSG00000154473.136050.141108061.33470-0.414005.148204.03870K562PUF60
BUB3ENSG00000154473.137012.370508401.30440-0.260703.886602.74620K562PUM2
BUB3ENSG00000154473.1310374.045304627.942001.1644031.4339029.58120K562PUS1
BUB3ENSG00000154473.137273.081204509.092600.6896019.9763018.34360K562RBM15
BUB3ENSG00000154473.133857.700003172.581900.282002.664601.36030K562RBM25
BUB3ENSG00000154473.132042.374702887.27140-0.499507.335105.71400K562RCC2
BUB3ENSG00000154473.133292.248304209.57360-0.354603.151401.97700K562NELFE
BUB3ENSG00000154473.132243.052303307.04840-0.560106.753005.10450K562RPS3
BUB3ENSG00000154473.131999.716002737.04010-0.452805.252403.70590K562SRFBP1
BUB3ENSG00000154473.132444.487803192.69580-0.385204.603503.18510K562SRSF4
BUB3ENSG00000154473.135868.006607033.59100-0.261403.083801.49400K562SUCLG1
BUB3ENSG00000154473.133176.164204138.78490-0.381903.649602.83310K562TARDBP
BUB3ENSG00000154473.132214.304403043.61790-0.458904.381403.18540K562TIAL1
BUB3ENSG00000154473.132677.132603233.62230-0.272502.349601.48910K562TRIM56
BUB3ENSG00000154473.133128.342504065.27500-0.378008.356307.19190K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for BUB3 is not available on ENCORE database.





2 RBPs can affect the splicing of BUB3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEBUB3ENSG00000154473.13chr10+124923335124923490124922127124922344124924562124924728-0.216000.000000.00000excludedK562AQR
SEBUB3ENSG00000154473.13chr10+1249233351249234901249221271249223441249245621249247280.136000.006770.08771includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for BUB3 is not avaliable on ENCORE database.