BECN1

General Information

Gene Name       : BECN1
Gene ID             : ENSG00000126581.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: BECN1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878BECN1ENSG00000126581.1269.2557.9763.61ENCSR000AEF
HepG2BECN1ENSG00000126581.1271.8872.5272.20ENCSR985KAT
K562BECN1ENSG00000126581.1249.1738.8644.02ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for BECN1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • BECN1 RNA is bound by 12 proteins.  







eCLIP assay for BECN1 is not avaliable on ENCORE database.





12 proteins are bound to BECN1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr174097610040976175-3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.692817.16658HepG2PRPF8
chr174097063040970689-3'-UTR,CDS,intron-Distal,intron-Proximal3.469286.25527HepG2PRPF8
chr174097067040970732-3'-UTR,CDS,intron-Distal,intron-Proximal4.772785.32906HepG2AQR
chr174097615640976221-3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.950295.22400HepG2DDX3X
chr174097154140971608-3'-UTR,CDS,intron-Distal,intron-Proximal3.527295.14253HepG2GRWD1
chr174097064440970695-3'-UTR,CDS,intron-Distal,intron-Proximal3.825643.18234K562BUD13
chr174097616040976258-3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.204153.68881HepG2SRSF1
chr174097063240970699-3'-UTR,CDS,intron-Distal,intron-Proximal3.565816.13978HepG2PPIG
chr174097076440970846-3'-UTR,CDS,intron-Distal,intron-Proximal4.016895.56912HepG2AQR
chr174097080040970859-3'-UTR,CDS,intron-Distal,intron-Proximal3.434906.82013HepG2PPIG
chr174097075040970823-3'-UTR,CDS,intron-Distal,intron-Proximal3.605727.89388HepG2PRPF8
chr174097621140976298-3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.887126.09067HepG2NCBP2
chr174097622140976260-3'-UTR,5'-UTR,intron-Distal3.932525.48791HepG2DDX3X
chr174096650540966559-3'-UTR,CDS,intron-Distal,intron-Proximal5.504817.02967HepG2PRPF8
chr174096273340962778-3'-UTR,intron-Distal,intron-Proximal3.282663.76090HepG2U2AF2
chr174097024240970270-CDS,intron-Distal4.241303.89826HepG2BCLAF1
chr174097283540972860-CDS,intron-Distal,intron-Proximal3.836053.22721K562YBX3
chr174097023640970358-CDS,intron-Distal,intron-Proximal3.105636.81934HepG2GRWD1
chr174097024040970346-CDS,intron-Distal3.973956.46803K562UCHL5
chr174097576540975799-CDS,intron-Distal,intron-Proximal3.422564.93175HepG2GRWD1
chr174097571740975809-CDS,intron-Distal,intron-Proximal4.8332411.43008HepG2PRPF8
chr174097575240975811-CDS,intron-Distal,intron-Proximal3.692755.24452HepG2PPIG
chr174097031240970390-CDS,intron-Distal3.256605.63425HepG2BCLAF1
chr174096790540968044-CDS,intron-Distal,intron-Proximal3.482258.16183HepG2BCLAF1
chr174097579940975869-CDS,intron-Distal,intron-Proximal3.859807.12207HepG2GRWD1
chr174096665940966711-CDS,intron-Distal,intron-Proximal4.3807111.45682HepG2U2AF2
chr174096798340968064-CDS,intron-Distal,intron-Proximal3.467865.74981HepG2GRWD1
chr174097581140975884-CDS,intron-Distal,intron-Proximal3.991476.72556HepG2PPIG
chr174097576440975814-CDS,intron-Distal,intron-Proximal4.118854.51688K562YBX3
chr174097019140970234-intron-Distal,intron-Proximal4.927655.68502HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for BECN1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for BECN1 is not available on ENCORE database.

  • 74 RBPs can affect the levels of BECN1.  








The Knockdown/knockout RNA-Seq assay for BECN1 is not available on ENCORE database.





74 RBPs can affect the gene expression of BECN1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
BECN1ENSG00000126581.81525.770801979.48100-0.375602.379401.50530HepG2ABCF1
BECN1ENSG00000126581.82291.271501756.811000.383107.342906.44980HepG2ACO1
BECN1ENSG00000126581.84114.016402429.300700.759909.165208.25950HepG2AKAP1
BECN1ENSG00000126581.82029.361501764.911100.201302.083401.40450HepG2AKAP8L
BECN1ENSG00000126581.82760.379802009.997400.457604.249503.28520HepG2ASCC1
BECN1ENSG00000126581.83103.421902676.069100.213602.641201.96900HepG2AUH
BECN1ENSG00000126581.82059.704001636.391100.331802.854202.24680HepG2BOP1
BECN1ENSG00000126581.82133.340901532.330800.477306.363005.25470HepG2CALR
BECN1ENSG00000126581.82744.312301909.650400.523005.578004.50330HepG2CIRBP
BECN1ENSG00000126581.81014.483101694.71330-0.740305.280004.22060HepG2CNOT7
BECN1ENSG00000126581.82066.982901630.430600.342203.417102.19150HepG2CPSF7
BECN1ENSG00000126581.83312.341402313.763600.5175011.3385010.21120HepG2CELF1
BECN1ENSG00000126581.81858.104902487.93080-0.421109.855608.59400HepG2DAZAP1
BECN1ENSG00000126581.81767.126901484.312100.251502.452401.36460HepG2DDX1
BECN1ENSG00000126581.81929.559101508.541600.355003.184402.46030HepG2DDX21
BECN1ENSG00000126581.8853.668301153.84160-0.434703.378901.83520HepG2DDX28
BECN1ENSG00000126581.83164.803202326.989700.443603.956003.21950HepG2DDX3X
BECN1ENSG00000126581.82108.283301523.144900.468903.627202.75570HepG2DDX55
BECN1ENSG00000126581.82358.070001705.975600.466902.195701.32870HepG2DDX59
BECN1ENSG00000126581.81818.522701442.492400.334105.707704.81900HepG2DNAJC2
BECN1ENSG00000126581.81778.958101262.630200.494504.433203.30960HepG2EIF3D
BECN1ENSG00000126581.82858.568702067.734900.467103.067002.34560HepG2EIF4B
BECN1ENSG00000126581.82927.531402454.438800.254203.376902.46790HepG2EIF4G1
BECN1ENSG00000126581.83719.639303072.518800.275604.135703.42610HepG2ETF1
BECN1ENSG00000126581.82575.187101998.858700.365402.732701.96820HepG2FIP1L1
BECN1ENSG00000126581.8720.333601528.76070-1.0856022.2453020.12270HepG2FUBP3
BECN1ENSG00000126581.82694.643601987.637700.438903.626302.86880HepG2G3BP1
BECN1ENSG00000126581.81945.567101677.139400.214102.332101.42930HepG2HDGF
BECN1ENSG00000126581.81940.654201469.423700.401203.904703.15640HepG2HNRNPA1
BECN1ENSG00000126581.82828.137902286.447400.306604.558603.40870HepG2HNRNPA2B1
BECN1ENSG00000126581.81112.604701634.41690-0.554806.479105.45410HepG2HNRNPC
BECN1ENSG00000126581.83212.609502013.068900.674209.995908.73860HepG2HNRNPK
BECN1ENSG00000126581.81317.093001625.20940-0.303302.010901.46560HepG2HNRNPLL
BECN1ENSG00000126581.82335.107401623.614500.524207.244106.29940HepG2HNRNPU
BECN1ENSG00000126581.82619.459002020.328500.374603.032302.33060HepG2IGF2BP2
BECN1ENSG00000126581.81169.899001614.51890-0.464703.188201.89070HepG2KHDRBS1
BECN1ENSG00000126581.82096.997901618.000800.374004.040303.06910HepG2MSI2
BECN1ENSG00000126581.82781.002502206.279100.333902.349901.76390HepG2NCBP2
BECN1ENSG00000126581.81255.094801607.15710-0.356702.989302.11280HepG2PARN
BECN1ENSG00000126581.82565.476102073.045100.307404.809404.04450HepG2PCBP1
BECN1ENSG00000126581.81162.871601448.14230-0.316502.941002.18370HepG2PPIL4
BECN1ENSG00000126581.81553.408001174.962200.402703.051102.20670HepG2PRPF8
BECN1ENSG00000126581.82464.487702109.460700.224302.811402.26010HepG2PTBP1
BECN1ENSG00000126581.82978.381802354.971200.338703.388902.73810HepG2PUF60
BECN1ENSG00000126581.82985.677102499.884100.256104.602603.87880HepG2PUM1
BECN1ENSG00000126581.82146.527701789.398900.262403.698803.00840HepG2PUS1
BECN1ENSG00000126581.83048.762802176.754300.485908.050406.69230HepG2RBM15
BECN1ENSG00000126581.81635.386102568.05020-0.6510014.5348013.53710HepG2RBM22
BECN1ENSG00000126581.82911.374902270.073400.358903.491502.73800HepG2RPLP0
BECN1ENSG00000126581.81679.035801228.678000.450404.958004.16210HepG2RPS19
BECN1ENSG00000126581.81966.610001445.927200.443609.007707.95040HepG2SAFB2
BECN1ENSG00000126581.81307.146401608.65180-0.299402.153101.52560HepG2SF3B1
BECN1ENSG00000126581.81928.325501686.240500.193402.428701.82070HepG2SMN1
BECN1ENSG00000126581.82565.167702292.310900.162201.751201.35060HepG2SRSF1
BECN1ENSG00000126581.83224.748602325.164800.4718010.677109.55520HepG2SRSF5
BECN1ENSG00000126581.82131.322001864.954700.192502.194301.69140HepG2SRSF9
BECN1ENSG00000126581.83097.227702644.375400.228003.542802.85540HepG2SUCLG1
BECN1ENSG00000126581.8961.328601349.94410-0.489805.232403.95950HepG2SUPT6H
BECN1ENSG00000126581.82234.697001516.261200.559505.154904.27740HepG2SUPV3L1
BECN1ENSG00000126581.82039.822901577.814900.370404.293303.69870HepG2TIAL1
BECN1ENSG00000126581.81895.480101591.736800.251902.954802.37650HepG2TRIM56
BECN1ENSG00000126581.82791.212902300.671400.278702.627801.77720HepG2TUFM
BECN1ENSG00000126581.82076.051101710.039100.279702.079001.52650HepG2U2AF1
BECN1ENSG00000126581.82216.735001731.171200.356606.127805.15520HepG2UPF1
BECN1ENSG00000126581.82122.331601779.381000.254202.976401.89470HepG2UTP18
BECN1ENSG00000126581.83124.395501903.953000.7145030.5468029.23000HepG2ZNF622
BECN1ENSG00000126581.8998.544601283.79690-0.362502.811201.57720K562ABCF1
BECN1ENSG00000126581.8807.172501167.70420-0.532708.202007.29600K562AGGF1
BECN1ENSG00000126581.8999.48630676.277500.563502.469501.64810K562BOP1
BECN1ENSG00000126581.81201.66600940.692000.353102.696301.43600K562CIRBP
BECN1ENSG00000126581.8828.909901255.48580-0.599003.243402.07750K562CNOT7
BECN1ENSG00000126581.82033.938201315.617300.6284014.6164013.23490K562DDX47
BECN1ENSG00000126581.8691.18120483.147300.516502.412901.47990K562EIF3A
BECN1ENSG00000126581.81029.92380736.137800.484406.032605.19050K562FXR1
BECN1ENSG00000126581.8870.39980686.588500.342102.310101.58430K562GPKOW
BECN1ENSG00000126581.8616.93870798.10770-0.371502.592702.01230K562HNRNPC
BECN1ENSG00000126581.81314.68160876.601700.584605.670103.83790K562HNRNPK
BECN1ENSG00000126581.81088.72390758.951200.520503.987202.85530K562HNRNPM
BECN1ENSG00000126581.81079.61810896.207700.268501.965501.38880K562PTBP1
BECN1ENSG00000126581.82503.602802029.786200.302602.617601.82450K562PUF60
BECN1ENSG00000126581.81344.35870859.326800.645507.954406.43040K562RBM22
BECN1ENSG00000126581.81164.30550754.253700.626205.559104.39920K562RPS19
BECN1ENSG00000126581.8522.72020757.10550-0.534503.013801.62210K562RRP9
BECN1ENSG00000126581.81297.81900889.175700.545405.397004.39170K562TARDBP
BECN1ENSG00000126581.8836.451401266.63120-0.5986010.929609.61890K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for BECN1 is not available on ENCORE database.





32 RBPs can affect the splicing of BECN1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEBECN1ENSG00000126581.8chr17-409676884096779040966541409666914096792540968013-0.095000.000090.00300excludedK562SRSF1
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096654140966611-0.374000.000000.00001excludedK562SF3B4
SEBECN1ENSG00000126581.8chr17-409679254096807240966541409666914097023840970433-0.146000.000020.00077excludedK562SF3B4
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096654140966611-0.377000.000000.00014excludedK562PRPF8
SEBECN1ENSG00000126581.8chr17-409679254096807240966541409666914097023840970433-0.095000.001520.05098excludedK562PRPF8
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096654140966611-0.129000.000170.01568excludedHepG2RBM22
SEBECN1ENSG00000126581.8chr17-409676884096779040966541409666914096792540968013-0.102000.000090.01977excludedK562MATR3
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096596540966026-0.199000.000000.00000excludedHepG2U2AF1
SEBECN1ENSG00000126581.8chr17-409705614097069840970238409704334097156540971627-0.404000.000000.00000excludedHepG2U2AF1
SEBECN1ENSG00000126581.8chr17-409679254096807240966541409666914097023840970433-0.117000.000200.00525excludedHepG2U2AF1
SEBECN1ENSG00000126581.8chr17-409676884096779040966541409666914096792540968013-0.090000.000180.04882excludedK562PCBP1
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096654140966611-0.078000.002580.05717excludedHepG2HNRNPK
SEBECN1ENSG00000126581.8chr17-4096367240963815409624314096294640965965409660260.061000.000300.03512includedHepG2DDX59
SEBECN1ENSG00000126581.8chr17-409708044097089540970238409704334097156540971627-0.235000.000140.00255excludedHepG2U2AF2
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096596540966026-0.140000.000000.00014excludedHepG2U2AF2
SEBECN1ENSG00000126581.8chr17-4096768840967790409665414096669140967925409681500.077000.010540.08475includedK562AQR
SEBECN1ENSG00000126581.8chr17-409636724096381540962733409629464096654140966611-0.264000.000000.00000excludedK562AQR
SEBECN1ENSG00000126581.8chr17-409705614097069840970238409704334097156540971627-0.087000.000360.00515excludedK562AQR
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096654140966611-0.231000.000230.01235excludedK562FXR1
SEBECN1ENSG00000126581.8chr17-409705614097069840970238409704334097156540971627-0.069000.000420.04326excludedHepG2SRSF7
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096596540966026-0.093000.000010.00135excludedHepG2DDX3X
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096654140966611-0.051000.006640.07710excludedK562PUS1
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096596540966026-0.146000.000000.00000excludedHepG2NCBP2
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096654140966611-0.373000.000000.00014excludedK562EFTUD2
SEBECN1ENSG00000126581.8chr17-409705614097069840970238409704334097156540971627-0.177000.000420.02680excludedK562EFTUD2
SEBECN1ENSG00000126581.8chr17-409659654096602640962877409629464096654140966691-0.384000.004890.08001excludedK562U2AF1
SEBECN1ENSG00000126581.8chr17-4096367240963815409624314096294640965965409660260.103000.000600.09719includedK562SBDS
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096654140966611-0.085000.004240.07805excludedHepG2SRSF1
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096654140966611-0.226000.000000.00000excludedHepG2SF3A3
SEBECN1ENSG00000126581.8chr17-409679254096807240966541409666914097023840970433-0.063000.002300.05846excludedHepG2SF3A3
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096596540966026-0.125000.000000.00005excludedHepG2IGF2BP3
SEBECN1ENSG00000126581.8chr17-4096367240963815409624314096294640965965409660260.089000.000820.05674includedK562HNRNPUL1
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096596540966026-0.133000.000000.00021excludedHepG2SF3B4
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096596540966026-0.148000.000830.03292excludedK562HNRNPU
SEBECN1ENSG00000126581.8chr17-4096367240963815409624314096294640965965409660260.135000.000000.00045includedK562CPSF6
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096654140966611-0.188000.001480.05461excludedK562SF3B1
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096596540966026-0.084000.000420.02199excludedHepG2HNRNPU
SEBECN1ENSG00000126581.8chr17-4096424840964374409636724096381540965965409660070.080000.000000.00016includedHepG2HNRNPC
SEBECN1ENSG00000126581.8chr17-409636724096381540962431409629464096596540966026-0.158000.000070.02376excludedK562SAFB
SEBECN1ENSG00000126581.8chr17-4096424840964374409636724096381540965965409660070.268000.000000.00002includedK562HNRNPC
A3SSBECN1ENSG00000126581.8chr17-4096792540968150409679254096807240970238409704620.127000.000000.00000longerK562AQR
A3SSBECN1ENSG00000126581.8chr17-4097080440970989409708044097089540971565409716570.162000.000000.00000longerK562AQR
A3SSBECN1ENSG00000126581.8chr17-4097023840970478409702384097043340970561409706980.130000.000000.00000longerK562AQR
A5SSBECN1ENSG00000126581.8chr17-4097572240975897409757654097589740972791409728590.075000.000200.00464longerK562AQR
A5SSBECN1ENSG00000126581.8chr17-4097615040976281409761724097628140975765409758970.213000.000070.00195longerK562AQR
A5SSBECN1ENSG00000126581.8chr17-409761504097628140976172409762814097576540975897-0.094000.001500.08613shorterHepG2HNRNPK
A5SSBECN1ENSG00000126581.8chr17-409761504097628140976172409762814097576540975897-0.208000.000450.06484shorterHepG2TIAL1
A5SSBECN1ENSG00000126581.8chr17-4097615040976281409761724097628140975765409758970.155000.000340.02429longerHepG2SRSF1
RIBECN1ENSG00000126581.8chr17-4097080440971627409708044097089540971565409716270.232000.000010.00056includedK562SF3B4
RIBECN1ENSG00000126581.8chr17-4097080440971627409708044097089540971565409716270.146000.000000.00000includedHepG2SF3A3
RIBECN1ENSG00000126581.8chr17-4097080440971627409708044097089540971565409716270.139000.000370.01162includedK562HNRNPC
RIBECN1ENSG00000126581.8chr17-409708044097162740970804409708954097156540971627-0.102000.000340.03765excludedK562NSUN2
RIBECN1ENSG00000126581.8chr17-4097080440971627409708044097089540971565409716270.285000.000000.00000includedHepG2U2AF2
RIBECN1ENSG00000126581.8chr17-4097080440971627409708044097089540971565409716270.084000.004130.07090includedK562RBM22
RIBECN1ENSG00000126581.8chr17-4097080440971627409708044097089540971565409716270.082000.000480.00627includedHepG2U2AF1
RIBECN1ENSG00000126581.8chr17-409708044097162740970804409708954097156540971627-0.089000.000230.01402excludedK562SUPV3L1
RIBECN1ENSG00000126581.8chr17-409708044097162740970804409708954097156540971627-0.257000.000150.01310excludedK562CPSF6
RIBECN1ENSG00000126581.8chr17-4097080440971627409708044097089540971565409716270.054000.002280.01858includedHepG2SF3B4
RIBECN1ENSG00000126581.8chr17-4097080440971627409708044097089540971565409716270.121000.000000.00001includedHepG2FUBP3
RIBECN1ENSG00000126581.8chr17-4097080440971627409708044097089540971565409716270.089000.000020.00053includedHepG2RBM22
RIBECN1ENSG00000126581.8chr17-409708044097162740970804409708954097156540971627-0.228000.001290.08393excludedK562FMR1
RIBECN1ENSG00000126581.8chr17-409708044097162740970804409708954097156540971627-0.286000.000050.01220excludedK562METAP2
RIBECN1ENSG00000126581.8chr17-4097080440971627409708044097089540971565409716270.224000.000000.00000includedK562AQR
MXEBECN1ENSG00000126581.8chr17-4097156540971627409727914097285940970238409704334097576540975897-0.183000.000000.000002includedHepG2U2AF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for BECN1 is not avaliable on ENCORE database.