AP1B1

General Information

Gene Name       : AP1B1
Gene ID             : ENSG00000100280.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: AP1B1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878AP1B1ENSG00000100280.1613.4838.1725.83ENCSR000AEF
HepG2AP1B1ENSG00000100280.1637.5219.9228.72ENCSR985KAT
K562AP1B1ENSG00000100280.1639.0432.2535.64ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for AP1B1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • AP1B1 RNA is bound by 15 proteins.  







eCLIP assay for AP1B1 is not avaliable on ENCORE database.





15 proteins are bound to AP1B1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr222972414629724440-3'-UTR,intron-Distal5.3934955.37029K562UPF1
chr222972389329723967-3'-UTR,intron-Distal4.710884.92727HepG2AKAP1
chr222972461329724691-3'-UTR,intron-Distal,intron-Proximal5.061517.92903HepG2UPF1
chr222972471429724807-3'-UTR,intron-Distal,intron-Proximal4.236837.35773HepG2UPF1
chr222972429229724389-3'-UTR,intron-Distal4.956008.06720HepG2AKAP1
chr222972445529724575-3'-UTR,intron-Distal5.256459.45100HepG2AKAP1
chr222972444329724537-3'-UTR,intron-Distal3.762347.79590K562AKAP1
chr222972445229724499-3'-UTR,intron-Distal5.9502811.61967K562UPF1
chr222972404229724143-3'-UTR,intron-Distal5.3466025.40505K562UPF1
chr222972390629723998-3'-UTR,intron-Distal5.2719634.25542K562UPF1
chr222972451629724575-3'-UTR,intron-Distal3.749265.91795HepG2UPF1
chr222972465629724737-3'-UTR,intron-Distal,intron-Proximal3.505774.66086HepG2AKAP1
chr222972402929724075-3'-UTR,intron-Distal4.379583.52477K562AKAP1
chr222972423729724412-3'-UTR,intron-Distal5.5075522.19816HepG2UPF1
chr222972444829724516-3'-UTR,intron-Distal4.683349.82827HepG2UPF1
chr222972387129723906-3'-UTR,intron-Distal5.7469611.61967K562UPF1
chr222972391129723960-3'-UTR,intron-Distal3.428493.72765HepG2UPF1
chr222972452429724612-3'-UTR,intron-Distal4.4674215.01187K562UPF1
chr222978441629784539-5'-UTR,intron-Distal,intron-Proximal5.4773111.38399K562DDX3X
chr222978441529784466-5'-UTR,intron-Distal3.819343.60441HepG2GRWD1
chr222975244729752469-CDS,intron-Distal3.895603.66655K562YBX3
chr222974518729745247-CDS,intron-Distal,intron-Proximal4.173684.08604HepG2PPIG
chr222975066629750736-CDS,intron-Distal3.792645.37099K562FXR2
chr222975240029752418-CDS,intron-Distal,intron-Proximal3.668935.83621K562AQR
chr222975241329752447-CDS,intron-Distal,intron-Proximal3.556564.70209K562YBX3
chr222975058529750640-CDS,intron-Distal,intron-Proximal4.395796.39176K562AQR
chr222973762829737736-CDS,intron-Distal5.255888.22878K562FXR2
chr222973822229738275-CDS,intron-Distal,intron-Proximal4.199636.39176K562AQR
chr222972631529726373-CDS,intron-Distal,intron-Proximal4.347418.77485HepG2PRPF8
chr222975487329754961-CDS,intron-Distal,intron-Proximal3.990517.22820K562YBX3
chr222973666029736760-CDS,intron-Distal4.260587.90093K562FXR2
chr222974769229747783-CDS,intron-Distal,intron-Proximal3.296433.79741HepG2GRWD1
chr222974711829747184-CDS,intron-Distal,intron-Proximal5.233475.35117HepG2PRPF8
chr222974521129745346-CDS,intron-Distal,intron-Proximal4.365923.11282HepG2G3BP1
chr222974603929746087-CDS,intron-Distal3.200198.03889K562YBX3
chr222975478529754900-CDS,intron-Distal4.678046.03821HepG2GRWD1
chr222975581229755857-CDS,intron-Distal,intron-Proximal4.344554.72838K562UCHL5
chr222974769229747704-CDS,intron-Distal,intron-Proximal3.286284.11795K562YBX3
chr222973669329736842-CDS,intron-Distal,intron-Proximal5.168428.07480K562FMR1
chr222975487829754962-CDS,intron-Distal,intron-Proximal4.450733.68892HepG2ZNF800
chr222975482229754909-CDS,intron-Distal3.992003.88696K562GRWD1
chr222972915829729236-intron-Distal4.1764478.33164HepG2NOLC1
chr222972626129726321-intron-Distal,intron-Proximal5.319796.44303K562AQR
chr222972916729729225-intron-Distal3.1480316.06439K562AATF
chr222973791129737972-intron-Distal5.549859.63974K562AQR
chr222973817829738222-intron-Distal,intron-Proximal4.284593.32531K562AQR
chr222973734329737487-intron-Distal,intron-Proximal4.075816.23585K562NOLC1
chr222975237029752400-intron-Distal,intron-Proximal4.388896.99120K562AQR
chr222972636029726366-intron-Distal,intron-Proximal4.138505.97994K562AQR
chr222972632129726360-intron-Distal,intron-Proximal4.8932110.64121K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for AP1B1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for AP1B1 is not available on ENCORE database.

  • 94 RBPs can affect the levels of AP1B1.  








The Knockdown/knockout RNA-Seq assay for AP1B1 is not available on ENCORE database.





94 RBPs can affect the gene expression of AP1B1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
AP1B1ENSG00000100280.121539.897101330.036400.211302.216301.65960HepG2ACO1
AP1B1ENSG00000100280.122527.461601468.288100.783506.624505.84050HepG2AKAP1
AP1B1ENSG00000100280.121543.627501851.43430-0.262302.864802.16790HepG2AUH
AP1B1ENSG00000100280.122199.863201398.039200.653909.149308.13900HepG2BOP1
AP1B1ENSG00000100280.12968.19540561.323000.786405.186604.13370HepG2CNOT7
AP1B1ENSG00000100280.12966.184401283.43210-0.409602.463601.80950HepG2CPSF6
AP1B1ENSG00000100280.121530.860501109.056100.464907.006406.07190HepG2CELF1
AP1B1ENSG00000100280.121536.574001192.501700.365605.920204.89330HepG2DAZAP1
AP1B1ENSG00000100280.121451.122501230.006600.238402.786301.94980HepG2DDX19B
AP1B1ENSG00000100280.12968.12560734.926400.397503.838902.48690HepG2DDX1
AP1B1ENSG00000100280.121248.18450823.083100.600606.945005.92040HepG2DDX21
AP1B1ENSG00000100280.12542.58290805.97750-0.570905.588104.28780HepG2DDX24
AP1B1ENSG00000100280.121022.59510714.284300.517602.617601.98030HepG2DNAJC2
AP1B1ENSG00000100280.121381.389701015.715600.443503.366602.35710HepG2EEF2
AP1B1ENSG00000100280.12519.93890758.38400-0.544602.817701.70110HepG2AGO1
AP1B1ENSG00000100280.121663.534301161.283600.518403.268802.62770HepG2EIF2S1
AP1B1ENSG00000100280.121727.028601283.093600.428602.603201.98210HepG2EIF4A3
AP1B1ENSG00000100280.121814.050002125.73600-0.228702.865802.25570HepG2ETF1
AP1B1ENSG00000100280.12471.17890737.02640-0.645406.291604.49480HepG2FAM120A
AP1B1ENSG00000100280.121785.580401295.378400.462903.070702.34190HepG2FXR1
AP1B1ENSG00000100280.12882.205701201.23740-0.445302.015501.44430HepG2G3BP1
AP1B1ENSG00000100280.12965.19310734.035300.394902.697401.81200HepG2GEMIN5
AP1B1ENSG00000100280.12757.63780519.646700.543902.986401.82930HepG2GRSF1
AP1B1ENSG00000100280.121570.082801217.332800.367002.050001.44320HepG2HNRNPK
AP1B1ENSG00000100280.121440.496101086.276000.407106.912505.89020HepG2HNRNPL
AP1B1ENSG00000100280.121374.53020803.905700.7737018.3143016.85730HepG2HNRNPU
AP1B1ENSG00000100280.12991.11810821.162300.271302.956702.20150HepG2ILF2
AP1B1ENSG00000100280.122564.309201755.159500.546904.318403.27470HepG2LARP4
AP1B1ENSG00000100280.122062.902901302.958200.662806.615105.67180HepG2MATR3
AP1B1ENSG00000100280.121866.024701333.545600.484603.744203.01160HepG2NCBP2
AP1B1ENSG00000100280.121527.382501182.482500.369104.112203.18210HepG2NOL12
AP1B1ENSG00000100280.121491.69650992.455800.587802.766601.31040HepG2NOLC1
AP1B1ENSG00000100280.12837.926501231.08570-0.555004.552503.59940HepG2NSUN2
AP1B1ENSG00000100280.121048.832801329.76690-0.342404.024303.32000HepG2PCBP1
AP1B1ENSG00000100280.12950.65350717.018900.406804.276703.38070HepG2PPIL4
AP1B1ENSG00000100280.121006.877701389.74060-0.464907.257606.07490HepG2PRPF4
AP1B1ENSG00000100280.121578.242201353.164400.221902.364801.85240HepG2PTBP1
AP1B1ENSG00000100280.121715.621501128.784700.603908.151307.20060HepG2PUF60
AP1B1ENSG00000100280.121760.432401198.256600.5549014.1683013.04400HepG2PUM1
AP1B1ENSG00000100280.121602.757501354.700800.242502.806802.18800HepG2PUS1
AP1B1ENSG00000100280.121817.882801465.346600.310903.404502.72110HepG2QKI
AP1B1ENSG00000100280.121422.605801776.71320-0.320703.435302.87570HepG2RBM22
AP1B1ENSG00000100280.121367.53990802.312100.7692011.6312010.47680HepG2RPS19
AP1B1ENSG00000100280.121276.44820868.063000.556203.743202.81640HepG2RPS2
AP1B1ENSG00000100280.12788.51310563.781500.483902.674801.88770HepG2RPS3A
AP1B1ENSG00000100280.12971.00060715.911000.439605.866704.98370HepG2SAFB2
AP1B1ENSG00000100280.122281.029401760.173900.373902.114701.52380HepG2SF3A3
AP1B1ENSG00000100280.121307.359001082.332300.272403.259502.50840HepG2SLBP
AP1B1ENSG00000100280.121307.63050832.394300.651502.430401.53610HepG2SMNDC1
AP1B1ENSG00000100280.12750.369201528.92780-1.026808.890407.49560HepG2SNRNP70
AP1B1ENSG00000100280.121481.656702006.71680-0.437608.522507.77520HepG2SRFBP1
AP1B1ENSG00000100280.121330.732201114.512700.255702.598701.98790HepG2SRSF5
AP1B1ENSG00000100280.12661.779001196.30880-0.8542019.6311018.40470HepG2SRSF9
AP1B1ENSG00000100280.121871.525701267.506000.5621013.1762011.98530HepG2SUCLG1
AP1B1ENSG00000100280.12313.25570949.31970-1.599608.005006.95060HepG2SUPV3L1
AP1B1ENSG00000100280.12329.557701321.82180-2.0039068.5879066.26080HepG2TAF15
AP1B1ENSG00000100280.12939.190701214.40850-0.370803.419002.49400HepG2TIA1
AP1B1ENSG00000100280.12940.49020781.127800.267801.902501.47040HepG2TIAL1
AP1B1ENSG00000100280.121156.98390788.128600.553809.246208.30790HepG2TRIM56
AP1B1ENSG00000100280.121408.271501102.777800.352703.200902.25430HepG2TUFM
AP1B1ENSG00000100280.122089.741901518.998500.460104.155603.39270HepG2U2AF1
AP1B1ENSG00000100280.121988.570501167.275000.768503.347602.42820HepG2UBE2L3
AP1B1ENSG00000100280.122003.340101561.003300.359806.006705.04180HepG2UPF1
AP1B1ENSG00000100280.12746.89860504.987600.564603.431802.20140HepG2XPO5
AP1B1ENSG00000100280.121157.756501371.51400-0.244402.775202.10170HepG2ZC3H8
AP1B1ENSG00000100280.122385.359001716.807500.4744012.6270011.67270HepG2ZNF622
AP1B1ENSG00000100280.123350.466702760.491000.279304.312703.63150K562AGGF1
AP1B1ENSG00000100280.123531.944302872.395000.298101.949701.39860K562AKAP8L
AP1B1ENSG00000100280.121813.219702799.92370-0.626807.986007.07540K562AQR
AP1B1ENSG00000100280.12987.859601358.25380-0.459403.914102.87520K562BOP1
AP1B1ENSG00000100280.121161.226801444.13030-0.314602.672201.90070K562CPSF6
AP1B1ENSG00000100280.122701.783903244.79520-0.264203.925903.16860K562DDX47
AP1B1ENSG00000100280.121011.65190704.405100.522106.229605.05400K562EIF3G
AP1B1ENSG00000100280.121427.420801728.82260-0.276402.074801.35990K562EIF4A3
AP1B1ENSG00000100280.122407.898701964.486200.293502.437001.64140K562FIP1L1
AP1B1ENSG00000100280.12992.662601627.86570-0.713608.084306.00050K562FKBP4
AP1B1ENSG00000100280.12944.270601469.52940-0.638107.482606.04090K562FMR1
AP1B1ENSG00000100280.12838.138001245.62870-0.571605.195603.90130K562FTO
AP1B1ENSG00000100280.12188.20980643.75070-1.7742022.9969020.35570K562G3BP2
AP1B1ENSG00000100280.121109.413701378.72250-0.313502.359101.62400K562GPKOW
AP1B1ENSG00000100280.122484.591603195.37270-0.363004.112703.19410K562GRSF1
AP1B1ENSG00000100280.121460.791901873.56760-0.359003.606102.93610K562HNRNPC
AP1B1ENSG00000100280.121986.527402663.19360-0.422903.159702.31250K562HSPD1
AP1B1ENSG00000100280.121805.689801046.381200.787002.955301.88470K562IGF2BP2
AP1B1ENSG00000100280.12670.874601177.43160-0.811507.368905.76270K562KRR1
AP1B1ENSG00000100280.121476.989701096.246500.430002.243401.41990K562MATR3
AP1B1ENSG00000100280.123549.917104305.67880-0.278502.564001.47950K562MSI2
AP1B1ENSG00000100280.122397.389902907.79740-0.278504.198103.21960K562MTPAP
AP1B1ENSG00000100280.122842.935903230.66110-0.184402.993502.22100K562NSUN2
AP1B1ENSG00000100280.121496.167301067.475100.487002.754202.09140K562PTBP1
AP1B1ENSG00000100280.123173.318304407.38550-0.473906.199704.98120K562PUF60
AP1B1ENSG00000100280.123460.765004688.29150-0.438007.424205.60800K562PUM1
AP1B1ENSG00000100280.123482.756904593.24480-0.399307.678306.05360K562PUM2
AP1B1ENSG00000100280.123307.765702775.580500.253002.815802.21800K562RBM15
AP1B1ENSG00000100280.122671.788302081.116900.360303.792902.51790K562SAFB
AP1B1ENSG00000100280.122609.562803188.08040-0.288903.697502.76310K562SF3A3
AP1B1ENSG00000100280.12799.328001311.45650-0.714307.023105.42890K562SF3B1
AP1B1ENSG00000100280.12827.41620669.108100.306302.240801.47320K562SF3B4
AP1B1ENSG00000100280.122898.969803266.27900-0.172102.257801.40310K562SRPK2
AP1B1ENSG00000100280.121537.372401046.601400.554702.645601.95280K562SRSF1
AP1B1ENSG00000100280.121741.073501301.747600.419403.098701.96920K562SRSF4
AP1B1ENSG00000100280.121595.60520988.732900.690403.613402.38150K562SRSF5
AP1B1ENSG00000100280.12379.55780631.89380-0.735403.641501.87520K562TAF15
AP1B1ENSG00000100280.121624.743901058.970600.617403.964403.10990K562TARDBP
AP1B1ENSG00000100280.121694.522201021.564600.730005.155003.98590K562TIA1
AP1B1ENSG00000100280.121636.263101003.070100.705904.635903.15640K562TRA2A
AP1B1ENSG00000100280.12398.02800644.23820-0.694707.748006.39560K562U2AF2
AP1B1ENSG00000100280.122918.727503425.55140-0.231003.321502.53860K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for AP1B1 is not available on ENCORE database.





8 RBPs can affect the splicing of AP1B1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEAP1B1ENSG00000100280.12chr22-2972570029725709297236702972488429726366297265210.335000.000000.00000includedHepG2U2AF1
SEAP1B1ENSG00000100280.12chr22-297257002972570929723670297248842972636629726521-0.178000.000050.00278excludedK562AKAP8L
SEAP1B1ENSG00000100280.12chr22-2972570029725709297236702972488429726366297265210.283000.000060.00842includedHepG2QKI
SEAP1B1ENSG00000100280.12chr22-297257002972570929723670297248842972636629726521-0.168000.000300.01367excludedK562UTP18
SEAP1B1ENSG00000100280.12chr22-2972570029725709297236702972488429726366297265210.390000.000000.00073includedHepG2FUBP3
SEAP1B1ENSG00000100280.12chr22-2973574229735763297349782973512229736644297368460.262000.000090.00568includedK562PTBP1
SEAP1B1ENSG00000100280.12chr22-297257002972570929723670297248842972636629726521-0.203000.000070.00198excludedK562HNRNPC
A3SSAP1B1ENSG00000100280.12chr22-2972777529727949297277752972790529730253297303390.116000.000030.00033longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for AP1B1 is not avaliable on ENCORE database.