AK3

General Information

Gene Name       : AK3
Gene ID             : ENSG00000147853.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: AK3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878AK3ENSG00000147853.1637.9430.0934.02ENCSR000AEF
HepG2AK3ENSG00000147853.1642.3484.4963.41ENCSR985KAT
K562AK3ENSG00000147853.1631.1933.4232.30ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for AK3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • AK3 RNA is bound by 33 proteins.  







eCLIP assay for AK3 is not avaliable on ENCORE database.





33 proteins are bound to AK3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr947113394711407-3'-UTR,intron-Distal3.688244.28919HepG2KHSRP
chr947116434711702-3'-UTR,intron-Distal3.730887.43720HepG2LIN28B
chr947111974711259-3'-UTR,intron-Distal4.493525.40698HepG2IGF2BP3
chr947121194712188-3'-UTR,intron-Distal3.548515.16549HepG2SUB1
chr947116304711699-3'-UTR,intron-Distal5.4885013.67930K562LIN28B
chr947118264711914-3'-UTR,intron-Distal4.368447.73669HepG2LIN28B
chr947118674711943-3'-UTR,intron-Distal4.010243.92497HepG2UPF1
chr947112024711264-3'-UTR,intron-Distal3.614907.47159K562IGF2BP2
chr947118204711908-3'-UTR,intron-Distal4.371769.68950K562LIN28B
chr947225024722579-3'-UTR,CDS,intron-Distal,intron-Proximal3.826229.02617HepG2PPIG
chr947113334711405-3'-UTR,intron-Distal4.177056.46185HepG2FUBP3
chr947121274712180-3'-UTR,intron-Distal3.409183.77257K562FAM120A
chr947112014711264-3'-UTR,intron-Distal3.641265.85910HepG2IGF2BP1
chr947411244741215-5'-UTR,intron-Distal6.1152922.44296HepG2DDX3X
chr947411184741180-5'-UTR,intron-Distal4.7297519.13432HepG2NCBP2
chr947410454741118-5'-UTR,CDS,intron-Distal3.447428.19027HepG2NCBP2
chr947410104741112-5'-UTR,CDS,intron-Distal3.6355629.37134HepG2DDX3X
chr947411804741226-5'-UTR,intron-Distal3.9191013.07890HepG2NCBP2
chr947408864740972-CDS,intron-Distal3.658814.29728K562GEMIN5
chr947409254740940-CDS,intron-Distal4.5482020.72149HepG2AQR
chr947184214718462-CDS,intron-Distal4.130115.79432HepG2BCLAF1
chr947408854740954-CDS,intron-Distal3.6089857.56136HepG2PRPF8
chr947408924740945-CDS,intron-Distal3.139915.62330K562PRPF8
chr947191334719163-CDS,intron-Distal,intron-Proximal3.203124.99842HepG2PPIG
chr947185004718539-CDS,intron-Distal,intron-Proximal4.045153.11149HepG2G3BP1
chr947185144718535-CDS,intron-Distal3.551606.60490HepG2BCLAF1
chr947409934741080-CDS,intron-Distal3.206456.19534HepG2GRSF1
chr947183624718452-CDS,intron-Distal,intron-Proximal3.714347.26133HepG2PRPF8
chr947129914713055-CDS,intron-Distal4.182395.70180K562PUM2
chr947184494718545-CDS,intron-Distal,intron-Proximal3.248088.84055HepG2BUD13
chr947192544719314-CDS,intron-Distal,intron-Proximal3.498587.76412HepG2U2AF2
chr947191364719164-CDS,intron-Distal3.884185.15500HepG2BCLAF1
chr947279104727956-intron-Distal3.582404.98672K562AQR
chr947375584737613-intron-Distal4.323083.38675HepG2ILF3
chr947407914740835-intron-Distal3.345133.04831K562RBM15
chr947351824735229-intron-Distal3.317487.88813HepG2ILF3
chr947287054728836-intron-Distal3.245825.49699K562ILF3
chr947301044730181-intron-Distal3.715838.03418HepG2QKI
chr947276564727779-intron-Distal3.015527.55360HepG2BCLAF1
chr947261664726249-intron-Distal3.7210110.20825HepG2HLTF
chr947262624726336-intron-Distal4.006569.09836HepG2BCLAF1
chr947138384713910-intron-Distal4.260736.72905K562EIF4G2
chr947243354724404-intron-Distal4.9128413.73149HepG2QKI
chr947141184714178-intron-Distal4.648254.19739K562EIF4G2
chr947258754725996-intron-Distal3.599175.04794HepG2KHSRP
chr947231754723270-intron-Distal3.354506.64740HepG2HNRNPL
chr947408574740902-intron-Distal5.6348138.83773K562AQR
chr947351664735230-intron-Distal4.676966.66835K562ILF3
chr947297714729836-intron-Distal3.132027.44875HepG2HNRNPC
chr947295974729672-intron-Distal3.311978.80788HepG2ILF3
chr947406614740745-intron-Distal3.306465.37154HepG2GTF2F1
chr947355814735635-intron-Distal3.501518.12901HepG2ILF3
chr947408994740925-intron-Distal4.6172021.04870HepG2AQR
chr947368154736888-intron-Distal3.183063.59765K562ILF3
chr947394244739479-intron-Distal4.7642222.87142HepG2ILF3
chr947285164728578-intron-Distal3.486574.41834HepG2HNRNPC
chr947287474728780-intron-Distal3.123963.29228HepG2ILF3
chr947409024740937-intron-Distal5.2053836.32291K562AQR
chr947394794739487-intron-Distal5.9544518.66729HepG2ILF3
chr947262494726400-intron-Distal3.5004010.64369HepG2HLTF
chr947279154727967-intron-Distal3.659954.40430HepG2AQR
chr947337174733780-intron-Distal3.953183.50377HepG2TAF15
chr947244324724510-intron-Distal3.668617.06840HepG2QKI
chr947380834738110-intron-Distal3.263804.76345K562KHSRP
chr947408154740932-intron-Distal3.5967024.16899HepG2RBM22
chr947381104738149-intron-Distal3.577094.52210K562KHSRP
chr947404504740499-intron-Distal3.600603.76275K562PTBP1
chr947258044725875-intron-Distal3.780453.20552HepG2KHSRP
chr947408384740882-intron-Distal4.163816.08301HepG2EFTUD2
chr947292474729312-intron-Distal3.571836.25214HepG2ILF3
chr947264214726467-intron-Distal3.673844.17155HepG2BCLAF1
chr947307754730859-intron-Distal3.195597.70143HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for AK3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for AK3 is not available on ENCORE database.

  • 98 RBPs can affect the levels of AK3.  








The Knockdown/knockout RNA-Seq assay for AK3 is not available on ENCORE database.





98 RBPs can affect the gene expression of AK3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
AK3ENSG00000147853.125916.398103576.152300.726207.249805.82120HepG2ABCF1
AK3ENSG00000147853.123588.982902710.506800.404907.644306.44460HepG2AKAP8L
AK3ENSG00000147853.123267.349604492.55310-0.4594011.3432010.11210HepG2AUH
AK3ENSG00000147853.123182.729403862.88430-0.279403.222902.39650HepG2CALR
AK3ENSG00000147853.123271.348002697.276900.278305.352204.48330HepG2CKAP4
AK3ENSG00000147853.121094.693002851.21460-1.3811017.1305015.29090HepG2CNOT7
AK3ENSG00000147853.122775.326202210.237800.328404.542103.23770HepG2YBX3
AK3ENSG00000147853.122666.222901637.539200.7032011.130509.21630HepG2CSTF2
AK3ENSG00000147853.123111.178903706.27380-0.252503.472202.76920HepG2CELF1
AK3ENSG00000147853.123462.723403985.45620-0.202803.569502.74660HepG2DAZAP1
AK3ENSG00000147853.123662.735702495.051800.5538017.9986016.30850HepG2DDX19B
AK3ENSG00000147853.125146.322402333.130501.1412031.5775029.65420HepG2DDX21
AK3ENSG00000147853.122729.564102282.772100.257802.313201.48550HepG2DDX24
AK3ENSG00000147853.123195.185302438.661000.389703.176101.80270HepG2DDX27
AK3ENSG00000147853.122667.466703473.93970-0.381103.943202.41410HepG2DDX47
AK3ENSG00000147853.124082.362603280.029400.315602.654701.66150HepG2DDX5
AK3ENSG00000147853.122433.632503812.23230-0.647506.953606.01010HepG2DDX6
AK3ENSG00000147853.123275.203302580.996300.343604.646003.80860HepG2DKC1
AK3ENSG00000147853.121886.214602151.09770-0.189602.400601.78530HepG2DNAJC2
AK3ENSG00000147853.123063.864602319.355000.401503.810602.74260HepG2EEF2
AK3ENSG00000147853.122755.818201882.876900.549403.607402.58280HepG2EIF3D
AK3ENSG00000147853.122802.171802203.014500.347003.865502.61570HepG2EIF3G
AK3ENSG00000147853.123797.957903098.335500.293602.749601.65940HepG2ESF1
AK3ENSG00000147853.123275.656205158.01900-0.6550022.1666020.74420HepG2ETF1
AK3ENSG00000147853.123579.913702636.278000.441304.273403.23550HepG2EWSR1
AK3ENSG00000147853.123314.477904086.35910-0.302002.253801.62680HepG2FXR1
AK3ENSG00000147853.122392.298701676.481600.512905.448704.18730HepG2GEMIN5
AK3ENSG00000147853.122210.635202575.62330-0.220502.661801.70110HepG2HDGF
AK3ENSG00000147853.123861.816102191.135600.817508.638507.59130HepG2HNRNPA1
AK3ENSG00000147853.123267.631503630.53720-0.151902.317301.69260HepG2HNRNPL
AK3ENSG00000147853.125735.958404237.999000.436603.897803.16280HepG2HNRNPLL
AK3ENSG00000147853.122072.621202421.09490-0.224202.786802.17700HepG2HNRNPU
AK3ENSG00000147853.126023.620904110.753200.551105.678404.79920HepG2MATR3
AK3ENSG00000147853.121014.432302396.50330-1.2403053.2198050.52640HepG2PARN
AK3ENSG00000147853.122508.835303688.35870-0.5560014.7714013.55060HepG2PCBP1
AK3ENSG00000147853.124267.503603064.718400.477502.959601.88700HepG2PCBP2
AK3ENSG00000147853.121851.615602159.42790-0.221902.177301.51560HepG2PPIL4
AK3ENSG00000147853.122422.697602010.837200.268702.011901.31960HepG2PRPF8
AK3ENSG00000147853.123005.686603772.40210-0.327803.560102.89540HepG2PUF60
AK3ENSG00000147853.123230.889202747.789100.233603.548802.86950HepG2PUS1
AK3ENSG00000147853.122121.980504064.63260-0.9377030.3675028.64730HepG2QKI
AK3ENSG00000147853.124858.569204311.156300.172401.764601.32700HepG2RBM22
AK3ENSG00000147853.123359.838802429.229600.467804.713303.31880HepG2RCC2
AK3ENSG00000147853.124447.284903590.343100.308702.875702.18100HepG2RPLP0
AK3ENSG00000147853.122571.299201832.053700.488906.655105.74800HepG2RPS19
AK3ENSG00000147853.123490.804502759.136100.339203.408802.52150HepG2RPS2
AK3ENSG00000147853.122527.215701989.176300.345302.609301.84370HepG2RRP9
AK3ENSG00000147853.122540.326001838.859500.466104.844703.61410HepG2SERBP1
AK3ENSG00000147853.126750.422803600.426500.9067010.999709.59410HepG2SF3A3
AK3ENSG00000147853.124544.557503907.398100.217803.055902.43820HepG2SF3B4
AK3ENSG00000147853.126536.559804667.609800.485703.164802.32700HepG2SNRNP70
AK3ENSG00000147853.126391.736904227.730600.5962022.0813020.93660HepG2SSB
AK3ENSG00000147853.121855.901104235.97420-1.1906079.0344076.62380HepG2SUCLG1
AK3ENSG00000147853.123064.052902439.047900.329003.757902.67560HepG2SUPT6H
AK3ENSG00000147853.123350.216002594.473700.368703.079302.36990HepG2SUPV3L1
AK3ENSG00000147853.123175.646702352.647500.432706.563405.85380HepG2TIAL1
AK3ENSG00000147853.121822.165302373.56960-0.381406.841806.02340HepG2TRIM56
AK3ENSG00000147853.121589.646103089.54470-0.9587017.8216016.17110HepG2U2AF1
AK3ENSG00000147853.124111.211603193.025800.364508.247107.14700HepG2UPF1
AK3ENSG00000147853.122842.052703281.99930-0.207602.423501.43190HepG2UTP18
AK3ENSG00000147853.123637.803003082.744100.238803.640802.96980HepG2UTP3
AK3ENSG00000147853.123080.401202553.971100.270302.160001.51310HepG2XRN2
AK3ENSG00000147853.123856.011502957.131300.382809.664508.53760HepG2ZC3H8
AK3ENSG00000147853.124100.925003511.720000.223704.276403.63580HepG2ZNF622
AK3ENSG00000147853.123361.711801969.745200.7711027.4328025.75840K562AGGF1
AK3ENSG00000147853.122986.009002164.496900.464102.331301.44130K562AKAP8
AK3ENSG00000147853.123365.293602049.620100.7153012.6414011.10120K562AKAP8L
AK3ENSG00000147853.122067.480602574.46760-0.316402.947301.66610K562APOBEC3C
AK3ENSG00000147853.123184.711902150.565700.5663012.1636010.06740K562ATP5C1
AK3ENSG00000147853.12983.34420671.742200.549704.971903.46510K562CCAR1
AK3ENSG00000147853.123049.942702353.917900.373605.004003.37420K562CCDC124
AK3ENSG00000147853.121652.050303283.74240-0.991108.948107.01590K562CNOT7
AK3ENSG00000147853.121296.138502050.60450-0.661806.592305.37680K562CPSF6
AK3ENSG00000147853.123061.863002311.051200.405804.199102.37330K562DDX19B
AK3ENSG00000147853.121748.063801376.887600.344203.425002.25020K562DDX3X
AK3ENSG00000147853.122097.152302501.05110-0.254103.178902.48770K562DDX47
AK3ENSG00000147853.123398.649202205.469200.6238015.7067013.26820K562DKC1
AK3ENSG00000147853.12718.555301114.17910-0.632806.233804.81670K562EFTUD2
AK3ENSG00000147853.121137.518401525.20080-0.423105.737104.75830K562EIF2S2
AK3ENSG00000147853.121523.275301193.146900.352302.238501.31790K562EIF3D
AK3ENSG00000147853.121130.560001438.53090-0.347602.827701.99770K562EIF4A3
AK3ENSG00000147853.122529.324102917.68590-0.206102.194701.35330K562EIF4G2
AK3ENSG00000147853.121065.263401496.01560-0.489907.281706.36340K562FXR1
AK3ENSG00000147853.122486.498601635.989600.603905.063804.04120K562G3BP2
AK3ENSG00000147853.121286.878401957.89160-0.605403.317402.44990K562GPKOW
AK3ENSG00000147853.121674.881702032.55950-0.279202.268001.58040K562GRSF1
AK3ENSG00000147853.12815.899901357.03200-0.734009.605808.54760K562HNRNPC
AK3ENSG00000147853.121568.088001942.59810-0.309002.720001.83470K562HNRNPU
AK3ENSG00000147853.124023.424602175.120800.8872012.5732010.41690K562KIF1C
AK3ENSG00000147853.121590.789501982.24130-0.317402.038201.31220K562MAGOH
AK3ENSG00000147853.123183.074202082.157000.612206.091904.26190K562MAK16
AK3ENSG00000147853.123649.203402436.690000.582605.509704.13520K562MBNL1
AK3ENSG00000147853.121141.063001911.09160-0.744006.861005.44890K562METAP2
AK3ENSG00000147853.123167.570001707.946600.891008.228806.39480K562NAA15
AK3ENSG00000147853.121391.148401763.87470-0.342502.324001.43160K562PCBP2
AK3ENSG00000147853.122525.051201625.356100.635507.170705.83220K562PCBP3
AK3ENSG00000147853.121982.218201246.709200.6689011.8748010.27170K562POLR2G
AK3ENSG00000147853.12798.622401084.21950-0.441103.201802.39430K562PRPF8
AK3ENSG00000147853.122528.515503183.37650-0.332303.517802.60020K562PUF60
AK3ENSG00000147853.124571.590202032.582401.1693029.2634027.47790K562PUS1
AK3ENSG00000147853.122512.173401561.060300.686304.627102.72470K562RAVER1
AK3ENSG00000147853.124006.673301980.510301.0164036.4331034.18610K562RBM15
AK3ENSG00000147853.121290.943401847.12500-0.516904.066903.02800K562RBM22
AK3ENSG00000147853.121317.808801800.20320-0.450003.695102.01230K562RBM34
AK3ENSG00000147853.121548.461902105.26900-0.443203.429902.30440K562RPS3
AK3ENSG00000147853.121507.061601108.726000.442702.846701.50020K562RRP9
AK3ENSG00000147853.12949.002801887.82260-0.9922012.2245010.73370K562SRSF1
AK3ENSG00000147853.121516.097402032.64870-0.423003.231302.07670K562SRSF4
AK3ENSG00000147853.121825.608601419.063100.363304.106202.24150K562SRSF9
AK3ENSG00000147853.121424.834101910.82600-0.423403.091402.34240K562TARDBP
AK3ENSG00000147853.121428.539701843.14800-0.367602.841802.01100K562TIA1
AK3ENSG00000147853.121750.810202051.99280-0.229002.834802.10760K562UPF1
AK3ENSG00000147853.122189.321201825.784900.261903.636702.67530K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for AK3 is not available on ENCORE database.





2 RBPs can affect the splicing of AK3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEAK3ENSG00000147853.12chr9-472250547226254719134471930747409364741318-0.057000.007470.09846excludedK562U2AF2
A3SSAK3ENSG00000147853.12chr9-4712974471319947129744713096471841847185370.057000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for AK3 is not avaliable on ENCORE database.