WDR45

General Information

Gene Name       : WDR45
Gene ID             : ENSG00000196998.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: WDR45)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878WDR45ENSG00000196998.1711.7713.3812.57ENCSR000AEF
HepG2WDR45ENSG00000196998.1725.8516.2621.05ENCSR985KAT
K562WDR45ENSG00000196998.1765.6055.0560.32ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for WDR45 is not avaliable on ENCORE database.



Proteins bound to RNA
  • WDR45 RNA is bound by 19 proteins.  







eCLIP assay for WDR45 is not avaliable on ENCORE database.





19 proteins are bound to WDR45 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX4893241748932479-3'-UTR,CDS,intron-Distal,intron-Proximal3.105383.18660HepG2PABPN1
chrX4893239348932474-3'-UTR,CDS,intron-Distal,intron-Proximal4.574739.31557K562PABPC4
chrX4893741648937545-5'-UTR,intron-Distal,intron-Proximal4.188885.88953K562DDX3X
chrX4893271748932805-CDS,intron-Distal,intron-Proximal3.086155.73570K562PRPF8
chrX4893547248935534-CDS,intron-Distal,intron-Proximal3.792208.40792HepG2PPIG
chrX4893519248935372-CDS,intron-Distal,intron-Proximal3.101373.88746HepG2U2AF1
chrX4893354248933561-CDS,intron-Distal,intron-Proximal3.160308.66768K562YBX3
chrX4893409048934165-CDS,intron-Distal3.210353.63043HepG2GRWD1
chrX4893358548933602-CDS,intron-Distal,intron-Proximal3.475919.84609K562YBX3
chrX4893408448934184-CDS,intron-Distal,intron-Proximal3.475716.70384HepG2PPIG
chrX4893442248934506-CDS,intron-Distal,intron-Proximal4.9543915.07951HepG2SF3B4
chrX4893441748934476-CDS,intron-Distal,intron-Proximal3.601188.74065K562SF3B4
chrX4893430148934339-CDS,intron-Distal,intron-Proximal4.127123.79199HepG2PPIG
chrX4893539248935471-CDS,intron-Distal,intron-Proximal5.120734.33932HepG2XRN2
chrX4893542148935539-CDS,intron-Distal,intron-Proximal4.301734.62931K562SRSF1
chrX4893352248933604-CDS,intron-Distal,intron-Proximal3.662327.64107HepG2PPIG
chrX4893256748932625-CDS,intron-Distal4.749158.25856K562SF3B4
chrX4893495948935015-intron-Distal3.425475.53307K562ZNF622
chrX4893542548935487-intron-Distal,intron-Proximal3.870763.95068K562DDX24
chrX4893505748935116-intron-Distal,intron-Proximal3.773263.62496HepG2TIA1
chrX4893407148934089-intron-Distal,intron-Proximal4.085045.47926K562AQR
chrX4893544448935496-intron-Distal,intron-Proximal3.319795.46476K562AQR
chrX4893405348934071-intron-Distal,intron-Proximal5.138506.75320K562AQR
chrX4893088048930987-intron-Distal3.491294.25667K562CSTF2T
chrX4893506448935114-intron-Distal,intron-Proximal3.296393.45280HepG2BCLAF1
chrX4893272648932791-intron-Distal,intron-Proximal3.442344.98672K562AQR
chrX4893542148935483-intron-Distal,intron-Proximal3.605183.13705K562BUD13
chrX4893270848932779-intron-Distal,intron-Proximal3.808825.03283HepG2RBFOX2
chrX4893521148935295-intron-Distal,intron-Proximal4.343546.22817K562DDX24
chrX4893258848932644-intron-Distal4.425745.32775HepG2SF3B4
chrX4893523448935268-intron-Distal,intron-Proximal3.248653.02345K562ZNF622
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for WDR45 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for WDR45 is not available on ENCORE database.

  • 96 RBPs can affect the levels of WDR45.  








The Knockdown/knockout RNA-Seq assay for WDR45 is not available on ENCORE database.





96 RBPs can affect the gene expression of WDR45 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
WDR45ENSG00000196998.11682.42780397.907600.7781011.9730010.89840HepG2ACO1
WDR45ENSG00000196998.11768.84530548.542800.487002.329401.83690HepG2AKAP1
WDR45ENSG00000196998.11532.70600399.794700.414003.288302.46040HepG2AKAP8L
WDR45ENSG00000196998.11834.86860453.876100.879209.443008.05130HepG2ASCC1
WDR45ENSG00000196998.11766.62630636.143900.269101.990101.39090HepG2AUH
WDR45ENSG00000196998.11450.56210303.099200.571802.296101.44660HepG2BCCIP
WDR45ENSG00000196998.11398.48730303.090300.394702.215701.52080HepG2CALR
WDR45ENSG00000196998.11622.54370397.842300.645908.431807.39350HepG2CKAP4
WDR45ENSG00000196998.11869.69290544.415100.675703.940403.02190HepG2CNOT7
WDR45ENSG00000196998.11747.10770507.990800.556406.538705.63060HepG2CELF1
WDR45ENSG00000196998.11476.00990368.017200.371102.978802.11530HepG2DDX19B
WDR45ENSG00000196998.11755.24530525.468800.523203.607102.90370HepG2DDX3X
WDR45ENSG00000196998.11539.23620298.038200.855305.232304.20850HepG2DDX55
WDR45ENSG00000196998.11631.72820451.373800.484902.728702.11580HepG2DDX6
WDR45ENSG00000196998.11480.27320380.695200.335102.089801.48840HepG2DKC1
WDR45ENSG00000196998.11724.94150466.897800.634703.788402.98930HepG2EIF4B
WDR45ENSG00000196998.111067.31890730.428100.547107.689506.77240HepG2ETF1
WDR45ENSG00000196998.11503.54610388.845600.372802.216101.46880HepG2EWSR1
WDR45ENSG00000196998.11687.82430484.970800.504002.805102.02890HepG2FIP1L1
WDR45ENSG00000196998.11996.05070448.831401.1499015.3727013.86830HepG2G3BP1
WDR45ENSG00000196998.11463.83640314.195500.561903.246602.55790HepG2GPKOW
WDR45ENSG00000196998.11513.96890379.900700.436003.352502.28340HepG2HDGF
WDR45ENSG00000196998.11875.22880454.456100.9454011.6385010.30020HepG2HNRNPK
WDR45ENSG00000196998.11572.83140358.215700.677208.069807.07490HepG2HNRNPU
WDR45ENSG00000196998.11813.72770587.125900.470802.655001.45450HepG2HSPD1
WDR45ENSG00000196998.11487.20610365.902600.413003.559602.73800HepG2ILF2
WDR45ENSG00000196998.11686.25900466.596300.556502.459601.67840HepG2LARP4
WDR45ENSG00000196998.11444.16840276.493000.683802.737701.69120HepG2METAP2
WDR45ENSG00000196998.11514.48800392.483400.390402.248201.51520HepG2MSI2
WDR45ENSG00000196998.11719.89550498.175200.531003.589602.87240HepG2NCBP2
WDR45ENSG00000196998.11704.06410541.599400.378403.075602.27200HepG2NOL12
WDR45ENSG00000196998.11481.37760354.550700.441103.392602.46350HepG2PARN
WDR45ENSG00000196998.11491.28000335.929400.548302.698501.67250HepG2PCBP2
WDR45ENSG00000196998.11387.16770229.758000.752704.018703.06740HepG2PRPF8
WDR45ENSG00000196998.11633.20490447.990000.499104.491103.83110HepG2PTBP1
WDR45ENSG00000196998.11988.23710548.839800.8484020.0785018.77810HepG2PUM1
WDR45ENSG00000196998.11611.48580324.079400.915905.276504.31940HepG2RAVER1
WDR45ENSG00000196998.111023.33940610.492300.7451011.8236010.90680HepG2RBM22
WDR45ENSG00000196998.11572.68120440.329800.379002.396601.76440HepG2RBM25
WDR45ENSG00000196998.11369.34770257.101700.522502.931602.30220HepG2RPS19
WDR45ENSG00000196998.11410.85530227.263100.854204.871603.86150HepG2RRP9
WDR45ENSG00000196998.11427.53290258.004600.728505.016303.76140HepG2SERBP1
WDR45ENSG00000196998.11407.00650296.804800.455402.228401.59140HepG2SF3B1
WDR45ENSG00000196998.11831.18090466.405800.8335013.4727012.32150HepG2SF3B4
WDR45ENSG00000196998.11485.47670371.987100.384003.070902.39770HepG2SMN1
WDR45ENSG00000196998.11485.05460330.238900.554502.501301.75940HepG2SNRNP70
WDR45ENSG00000196998.11958.40840689.510300.475006.027705.36700HepG2SRFBP1
WDR45ENSG00000196998.11370.67960486.83060-0.393202.598902.13650HepG2SRSF1
WDR45ENSG00000196998.11622.55880319.296200.963207.991806.21650HepG2SRSF3
WDR45ENSG00000196998.11684.53620510.484600.423204.121503.38620HepG2SRSF5
WDR45ENSG00000196998.11639.29510396.066000.690609.271108.36560HepG2SRSF9
WDR45ENSG00000196998.11411.71760598.62610-0.540005.775905.08670HepG2SSB
WDR45ENSG00000196998.11661.13930296.647701.1561010.069708.91370HepG2SUPV3L1
WDR45ENSG00000196998.11366.43960198.805300.882105.447604.11630HepG2TFIP11
WDR45ENSG00000196998.11483.21680224.193701.107802.896801.88450HepG2U2AF2
WDR45ENSG00000196998.11439.11820175.208301.3254013.4439011.79760HepG2UCHL5
WDR45ENSG00000196998.11304.35700406.51030-0.417502.448901.87790HepG2UTP3
WDR45ENSG00000196998.11473.61190349.503400.438303.513202.77030HepG2ZC3H8
WDR45ENSG00000196998.11717.98660463.077700.632609.388508.53320HepG2ZNF622
WDR45ENSG00000196998.11561.17500728.52700-0.376502.496901.50580K562CCAR1
WDR45ENSG00000196998.11878.34700693.156300.341502.453101.71080K562CPSF6
WDR45ENSG00000196998.11497.60040795.73260-0.677305.167002.70960K562YBX3
WDR45ENSG00000196998.111038.87720797.356700.381603.422702.24820K562DDX3X
WDR45ENSG00000196998.111062.361201319.53450-0.312803.476302.75720K562DDX47
WDR45ENSG00000196998.11506.59740830.42170-0.713003.790601.70010K562DNAJC2
WDR45ENSG00000196998.11931.13940702.986400.405402.657301.76500K562EFTUD2
WDR45ENSG00000196998.111051.31880875.904100.263302.539401.39240K562EIF2S1
WDR45ENSG00000196998.111421.245401023.278400.473906.700205.65330K562EIF2S2
WDR45ENSG00000196998.11514.27570741.04120-0.527002.428501.49100K562EIF3A
WDR45ENSG00000196998.11912.05470727.202900.326702.630601.37550K562EWSR1
WDR45ENSG00000196998.11922.595801203.85280-0.383903.556502.09710K562EXOSC5
WDR45ENSG00000196998.111092.78900841.185500.377402.989502.10580K562FIP1L1
WDR45ENSG00000196998.11696.04930866.36220-0.315802.556401.96980K562FXR1
WDR45ENSG00000196998.11307.96090501.05420-0.702203.460602.65230K562G3BP2
WDR45ENSG00000196998.11882.54250661.788600.415203.225102.36950K562GPKOW
WDR45ENSG00000196998.111071.132801363.52740-0.348202.949902.17070K562GRSF1
WDR45ENSG00000196998.111909.799901140.384100.7438010.872709.32230K562HSPD1
WDR45ENSG00000196998.111302.86640862.949600.594204.889503.35970K562IGF2BP2
WDR45ENSG00000196998.111139.94900877.474100.377402.573201.43650K562IGF2BP3
WDR45ENSG00000196998.111185.82950777.711800.608506.783704.46920K562LARP7
WDR45ENSG00000196998.11946.09360716.004800.401902.916001.34520K562LSM11
WDR45ENSG00000196998.11798.186901086.74890-0.445204.586003.56690K562MTPAP
WDR45ENSG00000196998.111742.955401112.826100.647202.894001.87450K562PABPN1
WDR45ENSG00000196998.111603.345201185.197800.435903.528801.73610K562PKM
WDR45ENSG00000196998.111020.67740719.408500.504504.734003.50630K562PSIP1
WDR45ENSG00000196998.111630.316202031.56520-0.317402.079401.37200K562PUF60
WDR45ENSG00000196998.112749.852802063.367600.414304.134703.49070K562PUS1
WDR45ENSG00000196998.111085.94480823.001300.399902.887201.47280K562RBM34
WDR45ENSG00000196998.111923.644401017.702600.918404.052402.51800K562SF1
WDR45ENSG00000196998.111479.386901191.531600.312103.514802.60190K562SF3A3
WDR45ENSG00000196998.111046.12280520.561501.006808.567607.01970K562SF3B4
WDR45ENSG00000196998.11536.33040802.41460-0.581205.253703.47990K562SLBP
WDR45ENSG00000196998.112032.214601168.777300.798003.671502.18400K562SNRNP200
WDR45ENSG00000196998.111119.61700815.510300.457103.039201.92780K562SRSF5
WDR45ENSG00000196998.11815.073601103.59950-0.437203.425601.88900K562SSRP1
WDR45ENSG00000196998.11816.536201178.10510-0.528906.441505.18110K562SYNCRIP
WDR45ENSG00000196998.111360.07220873.567500.638604.774603.83670K562TARDBP
WDR45ENSG00000196998.11717.72580521.863100.459703.225701.49680K562TBRG4
WDR45ENSG00000196998.111170.93700842.695800.474504.443903.37000K562TIA1
WDR45ENSG00000196998.111202.83170827.307000.539805.017303.46260K562TRA2A
WDR45ENSG00000196998.111604.463301318.326000.283303.344901.93940K562TROVE2
WDR45ENSG00000196998.11668.94600485.181900.463302.748801.65980K562U2AF1
WDR45ENSG00000196998.11631.66190501.251700.333502.128101.42420K562U2AF2
WDR45ENSG00000196998.11811.648501139.20170-0.489104.735103.65420K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for WDR45 is not available on ENCORE database.





15 RBPs can affect the splicing of WDR45 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEWDR45ENSG00000196998.11chrX-4893530148935406489343034893440948935495489355700.371000.000000.00000includedK562SRSF1
SEWDR45ENSG00000196998.11chrX-4893530148935406489343034893440948935495489355700.273000.000040.02811includedK562SMNDC1
SEWDR45ENSG00000196998.11chrX-4893530148935406489342754893440948935495489355700.217000.000000.00010includedK562AKAP8L
SEWDR45ENSG00000196998.11chrX-4893384948933934489335244893360448934088489341830.259000.000000.00000includedHepG2HNRNPK
SEWDR45ENSG00000196998.11chrX-4893530148935406489342754893440948935495489355700.190000.000010.00026includedK562PUS1
SEWDR45ENSG00000196998.11chrX-489353014893540648934303489344124893549548935570-0.341000.007840.09758excludedK562HNRNPC
A3SSWDR45ENSG00000196998.11chrX-4893430348934484489343034893440948935301489354060.311000.000010.00741longerK562HNRNPU
A3SSWDR45ENSG00000196998.11chrX-4893430348934484489343034893440948935301489354060.305000.000190.02568longerK562EFTUD2
A3SSWDR45ENSG00000196998.11chrX-489342754893441248934275489344094893530148935406-0.111000.001080.08344shorterK562AKAP8L
A3SSWDR45ENSG00000196998.11chrX-489332034893341248933203489333224893352448933604-0.265000.000190.07949shorterHepG2DROSHA
A3SSWDR45ENSG00000196998.11chrX-4893320348933412489332034893332248933524489336040.152000.002200.05016longerHepG2U2AF2
A3SSWDR45ENSG00000196998.11chrX-4893430348934484489343034893440948935301489354060.192000.000000.00251longerK562DROSHA
A3SSWDR45ENSG00000196998.11chrX-4893569948935878489356994893577148937409489375740.111000.000000.00000longerK562AQR
A3SSWDR45ENSG00000196998.11chrX-4893350248933742489335024893360448934088489341830.147000.000000.00000longerK562AQR
A3SSWDR45ENSG00000196998.11chrX-4893336248933432489333624893341248933524489336870.078000.000000.00000longerK562AQR
A3SSWDR45ENSG00000196998.11chrX-4893430348934484489343034893440948935301489354060.224000.000260.00206longerK562AQR
A3SSWDR45ENSG00000196998.11chrX-4893549548935597489354954893557048935699489357710.110000.000000.00000longerK562AQR
A3SSWDR45ENSG00000196998.11chrX-4893320348933412489332034893332248933524489336040.189000.000550.08306longerHepG2SFPQ
RIWDR45ENSG00000196998.11chrX-4893430348935570489343034893440948935495489355700.354000.000390.00837includedK562SF3B4
RIWDR45ENSG00000196998.11chrX-489353704893559348935370489354064893549548935593-0.147000.000070.00070excludedK562PUS1
RIWDR45ENSG00000196998.11chrX-4893430348935570489343034893440948935495489355700.266000.005290.08742includedK562SRSF1
RIWDR45ENSG00000196998.11chrX-4893430348935570489343034893440948935495489355700.226000.002410.02523includedK562EFTUD2
RIWDR45ENSG00000196998.11chrX-4893430348935570489343034893440948935495489355700.282000.000100.00080includedK562AQR
RIWDR45ENSG00000196998.11chrX-4893554348935771489355434893557048935699489357710.160000.000000.00000includedK562AQR
RIWDR45ENSG00000196998.11chrX-4893430348935570489343034893440948935495489355700.175000.000320.03053includedK562LARP4
MXEWDR45ENSG00000196998.11chrX-4893408848934183489353014893540648933524489336044893549548935570-0.153000.000110.018342includedK562XRCC6
MXEWDR45ENSG00000196998.11chrX-4893513948935270489353014893540648934303489344094893549548935570-0.098000.000620.027902includedK562HNRNPU

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for WDR45 is not avaliable on ENCORE database.