SEC61B

General Information

Gene Name       : SEC61B
Gene ID             : ENSG00000106803.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SEC61B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SEC61BENSG00000106803.9150.75228.00189.38ENCSR000AEF
HepG2SEC61BENSG00000106803.9215.34179.85197.59ENCSR985KAT
K562SEC61BENSG00000106803.9196.11144.21170.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SEC61B is not avaliable on ENCORE database.



Proteins bound to RNA
  • SEC61B RNA is bound by 13 proteins.  







eCLIP assay for SEC61B is not avaliable on ENCORE database.





13 proteins are bound to SEC61B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr9101992717101992765+3'-UTR3.012757.87234K562YBX3
chr9101992624101992721+3'-UTR,CDS3.0142211.93723K562PUM2
chr9101992761101992865+3'-UTR6.2798613.22795HepG2SUB1
chr9101992775101992842+3'-UTR3.990513.80143K562NOLC1
chr9101990189101990232+3'-UTR,CDS3.021305.79126HepG2LARP4
chr9101992672101992731+3'-UTR,CDS3.998084.54534K562IGF2BP2
chr9101990135101990212+3'-UTR,CDS,intron-Proximal4.389207.08280K562SF3B4
chr9101992665101992727+3'-UTR,CDS4.077967.57994HepG2SUB1
chr9101990187101990243+3'-UTR,CDS4.282368.77766HepG2RPS3
chr9101992724101992817+3'-UTR4.4645216.34075HepG2LARP4
chr9101992624101992724+3'-UTR,CDS5.2647126.71844HepG2LARP4
chr9101984902101984961+5'-UTR,CDS,intron-Proximal4.156486.95612HepG2PRPF8
chr9101984598101984608+5'-UTR,intron-Distal3.1174815.29200K562YBX3
chr9101984827101984829+5'-UTR,CDS,intron-Proximal3.277699.39295K562YBX3
chr9101984825101984862+5'-UTR,CDS,intron-Proximal3.434644.84415HepG2DDX3X
chr9101984627101984644+5'-UTR,intron-Distal3.3546121.49428K562YBX3
chr9101984600101984649+5'-UTR,CDS,intron-Distal,intron-Proximal3.795623.67661K562IGF2BP2
chr9101984831101984908+5'-UTR,CDS3.207329.56070HepG2LARP4
chr9101984601101984648+5'-UTR,CDS,intron-Distal3.103869.40856HepG2DDX3X
chr9101984827101984854+5'-UTR,CDS,intron-Proximal3.087247.94458K562DDX3X
chr9101984597101984649+5'-UTR,CDS,intron-Distal,intron-Proximal3.901623.27788HepG2IGF2BP3
chr9101984564101984598+5'-UTR,intron-Distal4.0066715.52136K562DDX3X
chr9101984598101984648+5'-UTR,CDS,intron-Distal4.0933832.78283K562DDX3X
chr9101984829101984875+5'-UTR,CDS3.2240715.33164K562YBX3
chr9101984872101984923+5'-UTR,CDS4.334986.15796HepG2DDX3X
chr9101992617101992663+CDS,intron-Proximal4.162498.01541K562SND1
chr9101984646101984690+CDS,intron-Distal,intron-Proximal4.773995.01842HepG2PRPF8
chr9101990262101990283+CDS,intron-Proximal3.708994.08796K562SND1
chr9101985434101985563+intron-Distal5.6051010.05299K562PTBP1
chr9101985422101985567+intron-Distal5.3482110.55181HepG2PTBP1
chr9101984927101984996+intron-Proximal3.308433.20886K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SEC61B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SEC61B is not available on ENCORE database.

  • 92 RBPs can affect the levels of SEC61B.  








The Knockdown/knockout RNA-Seq assay for SEC61B is not available on ENCORE database.





92 RBPs can affect the gene expression of SEC61B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SEC61BENSG00000106803.5705.31570908.97070-0.366003.790202.90580HepG2AKAP8L
SEC61BENSG00000106803.51668.426701256.121800.409403.144102.30580HepG2ASCC1
SEC61BENSG00000106803.51382.23320941.127000.554403.960002.83790HepG2BCCIP
SEC61BENSG00000106803.5783.01640519.657300.591405.203404.41460HepG2BOP1
SEC61BENSG00000106803.5973.66870635.613000.615207.546406.35940HepG2CALR
SEC61BENSG00000106803.5731.35620477.051400.616303.392602.63950HepG2CPSF6
SEC61BENSG00000106803.5937.85380603.332800.636308.957307.15540HepG2YBX3
SEC61BENSG00000106803.51574.190701173.686300.423507.520806.38580HepG2DAZAP1
SEC61BENSG00000106803.51002.62970836.714300.260902.600001.78840HepG2DDX19B
SEC61BENSG00000106803.5977.85070743.562500.395102.809201.78970HepG2DDX5
SEC61BENSG00000106803.51032.84250865.533200.254902.169301.55830HepG2DKC1
SEC61BENSG00000106803.5752.86030592.412900.345702.896402.17990HepG2DNAJC21
SEC61BENSG00000106803.5729.42250587.203100.312803.011702.33630HepG2DNAJC2
SEC61BENSG00000106803.5833.02150627.845800.407802.591001.69620HepG2EEF2
SEC61BENSG00000106803.5813.50890523.378400.636205.655404.06550HepG2EFTUD2
SEC61BENSG00000106803.51805.310801109.170600.702705.479304.35490HepG2EIF4G2
SEC61BENSG00000106803.51181.772901619.23060-0.454407.667006.75080HepG2ETF1
SEC61BENSG00000106803.51077.27530884.078900.285002.050901.33390HepG2EWSR1
SEC61BENSG00000106803.5545.91390873.35650-0.677904.680303.70000HepG2FIP1L1
SEC61BENSG00000106803.51530.698601098.010400.479203.440401.59180HepG2FMR1
SEC61BENSG00000106803.5704.11740913.41410-0.375502.802702.01090HepG2FUBP3
SEC61BENSG00000106803.5962.554101242.13100-0.367902.380701.76030HepG2G3BP1
SEC61BENSG00000106803.5702.09930863.73540-0.298902.697901.73070HepG2HDGF
SEC61BENSG00000106803.5815.41010598.088600.447102.293501.70020HepG2HNRNPA1
SEC61BENSG00000106803.51411.963301078.625100.388404.473203.33450HepG2HNRNPA2B1
SEC61BENSG00000106803.5714.94270516.018500.470303.066702.40840HepG2HNRNPLL
SEC61BENSG00000106803.5882.55940512.282600.784706.507404.65440HepG2HSPD1
SEC61BENSG00000106803.5799.63660675.056800.244201.952201.32320HepG2ILF2
SEC61BENSG00000106803.5639.57690827.01780-0.370804.192402.95010HepG2KIF1C
SEC61BENSG00000106803.5946.09070648.195900.545404.509203.05720HepG2LARP7
SEC61BENSG00000106803.51221.70910680.319700.8445010.687408.44310HepG2LIN28B
SEC61BENSG00000106803.5894.01150485.502700.880707.284305.01810HepG2NKRF
SEC61BENSG00000106803.5987.46160469.434801.072708.296106.71540HepG2PABPC1
SEC61BENSG00000106803.5788.18040497.652400.663304.927502.52750HepG2PPIG
SEC61BENSG00000106803.5976.956601266.43950-0.374404.406703.75090HepG2PTBP1
SEC61BENSG00000106803.51470.940301179.309800.318704.611303.88710HepG2PUM1
SEC61BENSG00000106803.5731.14560921.46550-0.333803.553002.87340HepG2PUS1
SEC61BENSG00000106803.5807.491901371.54490-0.7643013.5735012.34040HepG2QKI
SEC61BENSG00000106803.5766.73870997.51600-0.379603.469802.51880HepG2RBM15
SEC61BENSG00000106803.5953.913501409.40980-0.563209.427908.53690HepG2NELFE
SEC61BENSG00000106803.5849.397701312.70220-0.6280011.3441010.22430HepG2RECQL
SEC61BENSG00000106803.5694.56680979.70430-0.496204.168103.35710HepG2RPLP0
SEC61BENSG00000106803.5389.60390495.93420-0.348101.953001.42910HepG2RPS19
SEC61BENSG00000106803.5710.98410515.762900.463002.416101.66620HepG2RPS3A
SEC61BENSG00000106803.51593.98160588.530801.4373062.4571060.09650HepG2SAFB2
SEC61BENSG00000106803.5249.75340497.72080-0.994809.543607.82890HepG2SERBP1
SEC61BENSG00000106803.5792.05570510.721000.633005.636704.65780HepG2SF3B1
SEC61BENSG00000106803.51120.070701318.49310-0.235302.123901.59560HepG2SF3B4
SEC61BENSG00000106803.51378.164301065.196000.371505.487504.55680HepG2SLBP
SEC61BENSG00000106803.5909.68660686.319300.406405.108704.27880HepG2SMN1
SEC61BENSG00000106803.5575.71550303.203200.925002.726001.42640HepG2SNRNP200
SEC61BENSG00000106803.5780.37260568.279400.457502.000101.34070HepG2SNRNP70
SEC61BENSG00000106803.5774.342301119.65250-0.532008.546407.67030HepG2SRSF9
SEC61BENSG00000106803.52046.889901327.049000.6251014.0959013.11880HepG2SSB
SEC61BENSG00000106803.51434.985101247.478400.201901.904601.37080HepG2SUCLG1
SEC61BENSG00000106803.5778.58730516.776900.591202.780901.45230HepG2SUGP2
SEC61BENSG00000106803.5788.31950589.758000.418603.256502.24200HepG2SUPT6H
SEC61BENSG00000106803.5519.851401237.05220-1.2507032.0657030.43200HepG2TAF15
SEC61BENSG00000106803.5713.783701136.64170-0.671209.341907.82360HepG2TIA1
SEC61BENSG00000106803.51000.04720647.902000.6261010.281209.29930HepG2TRIM56
SEC61BENSG00000106803.51615.476001163.357900.473605.274103.81290K562AKAP8
SEC61BENSG00000106803.51519.512101101.593600.463904.953604.06940K562AKAP8L
SEC61BENSG00000106803.51358.619401155.862100.233102.129701.33580K562ATP5C1
SEC61BENSG00000106803.51093.00960855.311000.353702.626101.38180K562CIRBP
SEC61BENSG00000106803.5780.234301037.01390-0.410504.765103.94360K562DDX47
SEC61BENSG00000106803.51438.978001185.309800.279703.004802.08520K562DKC1
SEC61BENSG00000106803.5863.15690592.017100.543904.533703.34880K562EFTUD2
SEC61BENSG00000106803.51406.892101141.352800.301703.060602.31050K562EIF2S2
SEC61BENSG00000106803.5450.80060600.99340-0.414902.909801.60580K562EXOSC5
SEC61BENSG00000106803.5660.63940828.76000-0.327102.652401.53400K562GLRX3
SEC61BENSG00000106803.51083.57580488.406101.149505.530903.58120K562HNRNPA2B1
SEC61BENSG00000106803.5430.10180650.15050-0.596105.113404.32430K562HNRNPC
SEC61BENSG00000106803.5893.20930566.619600.656505.694404.29480K562HNRNPM
SEC61BENSG00000106803.51290.05860933.831300.466104.296503.31090K562HSPD1
SEC61BENSG00000106803.51423.862201169.019300.284402.686801.87500K562KIF1C
SEC61BENSG00000106803.51399.166401119.077100.322203.086801.93480K562MAK16
SEC61BENSG00000106803.5655.97480871.33750-0.409604.556203.54040K562MTPAP
SEC61BENSG00000106803.51242.73890917.941300.436902.689401.82090K562NAA15
SEC61BENSG00000106803.5741.10120968.10930-0.385505.037704.07280K562NSUN2
SEC61BENSG00000106803.51236.37670426.922501.5340010.628908.25560K562PABPN1
SEC61BENSG00000106803.5553.54790764.46140-0.465702.997902.13270K562PCBP3
SEC61BENSG00000106803.51076.97390782.026500.461604.012403.00100K562PPIG
SEC61BENSG00000106803.51171.77750507.274001.207804.638802.57710K562PPP1R8
SEC61BENSG00000106803.51184.70680576.101101.0400015.3140013.53550K562PRPF8
SEC61BENSG00000106803.51550.418301857.93080-0.261002.713701.76320K562PUM2
SEC61BENSG00000106803.51403.325701064.441900.398704.840704.07670K562RBM15
SEC61BENSG00000106803.5994.15900586.814600.760507.224505.88960K562RPS19
SEC61BENSG00000106803.5279.07770492.97040-0.820804.882302.80710K562SERBP1
SEC61BENSG00000106803.51037.41080390.261901.410405.022203.24670K562SF1
SEC61BENSG00000106803.5780.19260955.31380-0.292102.324401.57090K562SF3A3
SEC61BENSG00000106803.51040.83550448.455801.214606.512704.35550K562SNRNP200
SEC61BENSG00000106803.5370.80060504.16350-0.443202.607101.62130K562SRFBP1
SEC61BENSG00000106803.5702.94590978.74290-0.477506.579905.20440K562SRPK2
SEC61BENSG00000106803.51128.73500798.797800.498705.275204.30410K562SRSF1
SEC61BENSG00000106803.5974.71620754.357900.369602.681201.65140K562SRSF5
SEC61BENSG00000106803.5494.89650667.43200-0.431503.493801.77170K562SRSF9
SEC61BENSG00000106803.51213.89750536.242101.178606.089703.74860K562SUPT6H
SEC61BENSG00000106803.51104.57730808.475900.450103.704502.88130K562TARDBP
SEC61BENSG00000106803.5956.47920779.855700.294402.058901.36010K562TIA1
SEC61BENSG00000106803.5396.62950560.67830-0.499403.028202.04570K562TIAL1
SEC61BENSG00000106803.5973.94260765.174700.347902.372701.37800K562TRA2A
SEC61BENSG00000106803.51578.366902010.44770-0.349103.588501.97400K562UBE2L3
SEC61BENSG00000106803.5698.81210878.34800-0.329902.105901.34350K562WDR3
SEC61BENSG00000106803.5747.77810913.40200-0.288602.095301.35170K562WDR43
SEC61BENSG00000106803.5901.39830455.731400.983903.815901.75030K562XPO5
SEC61BENSG00000106803.51282.01150527.568501.280907.822604.61420K562YTHDC2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SEC61B is not available on ENCORE database.






No RBPs affect the alternative splcing events of SEC61B on ENCORE database.





The Knockdown/knockout RNA-Seq assay for SEC61B is not avaliable on ENCORE database.