SCAI

General Information

Gene Name       : SCAI
Gene ID             : ENSG00000173611.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SCAI)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SCAIENSG00000173611.172.012.352.18ENCSR000AEF
HepG2SCAIENSG00000173611.172.152.942.54ENCSR985KAT
K562SCAIENSG00000173611.172.252.742.50ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SCAI is not avaliable on ENCORE database.



Proteins bound to RNA
  • SCAI RNA is bound by 17 proteins.  







eCLIP assay for SCAI is not avaliable on ENCORE database.





17 proteins are bound to SCAI RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr9127709907127709980-3'-UTR,intron-Distal4.063144.92393K562PUM2
chr9127710025127710123-3'-UTR,intron-Distal4.436974.92524K562TARDBP
chr9127714399127714492-3'-UTR,intron-Distal4.590076.58261K562KHSRP
chr9127733625127733677-3'-UTR,CDS,intron-Distal,intron-Proximal4.951736.35567HepG2PRPF8
chr9127905663127905724-5'-UTR,CDS,intron-Distal4.299215.47892K562DDX3X
chr9127905713127905774-5'-UTR,CDS,intron-Distal,intron-Proximal3.437143.52645HepG2NCBP2
chr9127781385127781479-CDS,intron-Distal,intron-Proximal3.744995.26861K562DDX24
chr9127764309127764413-CDS,intron-Distal,intron-Proximal4.355034.10688K562KHSRP
chr9127765358127765413-CDS,intron-Distal,intron-Proximal3.176913.20886K562PRPF8
chr9127757266127757346-CDS,intron-Distal,intron-Proximal4.069204.69223K562SF3B4
chr9127781208127781230-CDS,intron-Distal4.205794.10264K562ZNF622
chr9127781124127781183-CDS,intron-Distal3.789115.08507K562ZNF622
chr9127765755127765800-CDS,intron-Distal4.395614.43680K562ZNF622
chr9127781385127781485-CDS,intron-Distal,intron-Proximal3.942177.90527K562ZNF622
chr9127765762127765860-CDS,intron-Distal,intron-Proximal3.936033.31221K562U2AF1
chr9127904827127904877-intron-Distal,intron-Proximal3.343594.02462K562TIA1
chr9127888141127888216-intron-Distal4.772387.44287K562TARDBP
chr9127852519127852636-intron-Distal4.244266.90077HepG2PTBP1
chr9127886872127886960-intron-Distal4.122444.13641K562TARDBP
chr9127852519127852628-intron-Distal6.0858013.96503K562PTBP1
chr9127852638127852718-intron-Distal3.343294.24981K562MATR3
chr9127888592127888667-intron-Distal3.848595.82228HepG2RBFOX2
chr9127852511127852638-intron-Distal3.800424.72029K562MATR3
chr9127750276127750359-intron-Distal3.955233.69425K562TARDBP
chr9127852628127852713-intron-Distal5.051645.89856K562PTBP1
chr9127852528127852758-intron-Distal3.231234.69218HepG2MATR3
chr9127773065127773157-intron-Distal3.394493.14999K562EXOSC5
chr9127888568127888639-intron-Distal4.356953.06537K562RBFOX2
chr9127779206127779298-intron-Distal3.582343.62418K562PTBP1
chr9127874079127874195-intron-Distal4.105553.23532K562MATR3
chr9127762442127762558-intron-Distal3.896563.45805K562KHSRP
chr9127852549127852720-intron-Distal4.441714.32196HepG2PCBP2
chr9127774726127774783-intron-Distal4.536473.89080K562EXOSC5
chr9127817649127817792-intron-Distal4.470035.41654K562KHSRP
chr9127733862127733948-intron-Distal,intron-Proximal4.053133.45805K562KHSRP
chr9127893334127893383-intron-Distal3.635513.04123K562LIN28B
chr9127810775127810829-intron-Distal3.428283.30744K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SCAI is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SCAI is not available on ENCORE database.

  • 94 RBPs can affect the levels of SCAI.  








The Knockdown/knockout RNA-Seq assay for SCAI is not available on ENCORE database.





94 RBPs can affect the gene expression of SCAI :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SCAIENSG00000173611.13299.54540426.24310-0.508904.190103.47090HepG2ACO1
SCAIENSG00000173611.13320.81960549.42720-0.776205.300104.59230HepG2AKAP1
SCAIENSG00000173611.13313.94790428.23630-0.447903.222902.40220HepG2AKAP8L
SCAIENSG00000173611.13227.57080454.61240-0.998308.494507.17040HepG2ASCC1
SCAIENSG00000173611.13163.39560362.49140-1.149607.753906.14240HepG2BCCIP
SCAIENSG00000173611.13235.43190344.55920-0.549402.943102.32830HepG2BOP1
SCAIENSG00000173611.13326.57820438.72470-0.425902.576701.83060HepG2CALR
SCAIENSG00000173611.13331.03510426.13920-0.364302.499901.86140HepG2CKAP4
SCAIENSG00000173611.13328.45620564.07100-0.780204.458303.48380HepG2CNOT7
SCAIENSG00000173611.13255.35810395.23240-0.630204.398403.02170HepG2CPSF7
SCAIENSG00000173611.13256.89450389.10110-0.599004.632403.31750HepG2YBX3
SCAIENSG00000173611.13291.87310543.73640-0.897606.245905.35290HepG2CELF1
SCAIENSG00000173611.13352.38020526.32590-0.578803.606902.90350HepG2DDX3X
SCAIENSG00000173611.13182.40800356.39070-0.966305.722704.65900HepG2DDX55
SCAIENSG00000173611.13210.84990452.08660-1.100409.159608.10550HepG2DDX6
SCAIENSG00000173611.13229.36910382.06550-0.736106.359305.32940HepG2DNAJC21
SCAIENSG00000173611.13326.02370434.63980-0.414801.919401.41520HepG2EIF2S1
SCAIENSG00000173611.13384.75890231.871400.730505.417004.32750HepG2FUBP3
SCAIENSG00000173611.13332.11620449.56110-0.436802.159801.56910HepG2G3BP1
SCAIENSG00000173611.13266.47520453.27030-0.766402.703801.69940HepG2GNB2L1
SCAIENSG00000173611.13262.12150358.60840-0.452201.900701.36370HepG2GPKOW
SCAIENSG00000173611.13328.10430476.74620-0.539102.714601.36190HepG2HNRNPA0
SCAIENSG00000173611.13290.28970385.72580-0.410102.084201.51410HepG2HNRNPA1
SCAIENSG00000173611.13261.78000426.21320-0.703207.069506.13590HepG2HNRNPU
SCAIENSG00000173611.13229.85810456.97940-0.991408.453507.34170HepG2IGF2BP2
SCAIENSG00000173611.13315.15800435.36250-0.466103.648602.81630HepG2ILF2
SCAIENSG00000173611.13287.08280389.63260-0.440603.231902.13130HepG2KIF1C
SCAIENSG00000173611.13443.06070611.48000-0.464802.448701.67050HepG2LARP4
SCAIENSG00000173611.13280.28070487.48500-0.798505.492704.62800HepG2MATR3
SCAIENSG00000173611.13180.90940333.70190-0.883302.802501.74400HepG2METAP2
SCAIENSG00000173611.13353.69560579.93280-0.713403.845202.94590HepG2NOL12
SCAIENSG00000173611.13245.30790421.87650-0.782207.868306.55790HepG2PARN
SCAIENSG00000173611.13291.10120380.14790-0.385002.275101.60010HepG2PPIL4
SCAIENSG00000173611.13514.56970346.969800.568505.327204.28900HepG2PRPF4
SCAIENSG00000173611.13385.37320553.53890-0.522402.948502.33670HepG2PUF60
SCAIENSG00000173611.13326.96800587.53850-0.845505.036304.28410HepG2PUM1
SCAIENSG00000173611.13404.27180587.15130-0.538403.197602.47640HepG2PUM2
SCAIENSG00000173611.13329.49850434.15460-0.397902.803102.18460HepG2PUS1
SCAIENSG00000173611.13651.53990440.472000.564705.305404.48120HepG2QKI
SCAIENSG00000173611.13385.72750517.15270-0.423002.625501.78800HepG2RBM15
SCAIENSG00000173611.13608.99670399.767000.607205.401104.48780HepG2RBM25
SCAIENSG00000173611.13610.98780421.593600.535205.252004.43720HepG2RECQL
SCAIENSG00000173611.13181.33110310.17270-0.774402.819002.19930HepG2RPS19
SCAIENSG00000173611.13272.50540379.56100-0.478003.386802.68650HepG2SAFB2
SCAIENSG00000173611.13222.18300442.63100-0.9944013.1577011.91590HepG2SMN1
SCAIENSG00000173611.13203.52700376.91130-0.889003.431802.55630HepG2SNRNP70
SCAIENSG00000173611.13536.91050441.985100.280601.724201.32630HepG2SRSF1
SCAIENSG00000173611.13338.56250546.45810-0.690704.395103.63960HepG2SRSF5
SCAIENSG00000173611.13737.70100559.114300.399803.565803.00000HepG2SSB
SCAIENSG00000173611.13422.20150621.54270-0.557903.195402.53660HepG2SUCLG1
SCAIENSG00000173611.13219.74150327.22560-0.574503.842302.74600HepG2SUPT6H
SCAIENSG00000173611.13192.12040354.80290-0.885004.873304.01400HepG2SUPV3L1
SCAIENSG00000173611.13823.98480397.299701.0523019.1436017.85960HepG2TAF15
SCAIENSG00000173611.13143.57390237.82500-0.728103.258802.18120HepG2TFIP11
SCAIENSG00000173611.13257.42320417.84820-0.698806.735805.92340HepG2TRIM56
SCAIENSG00000173611.13384.11710540.67380-0.493202.819501.93880HepG2TUFM
SCAIENSG00000173611.13335.20170491.66080-0.552605.217004.30610HepG2UPF1
SCAIENSG00000173611.13226.12870349.26390-0.627202.916802.17210HepG2XRN2
SCAIENSG00000173611.13474.88400342.425000.471703.921603.14530HepG2ZC3H8
SCAIENSG00000173611.13368.40620540.73480-0.553606.054505.32720HepG2ZNF622
SCAIENSG00000173611.131226.169801544.61110-0.333103.971303.31370K562AGGF1
SCAIENSG00000173611.131199.117701697.32730-0.501303.766202.58000K562AKAP8
SCAIENSG00000173611.131178.413001607.24600-0.447704.347703.52330K562AKAP8L
SCAIENSG00000173611.13776.198101007.62640-0.376502.923801.64610K562APOBEC3C
SCAIENSG00000173611.131249.347301686.40340-0.432805.717304.34870K562ATP5C1
SCAIENSG00000173611.131148.587301845.86840-0.6844011.713009.30000K562CCDC124
SCAIENSG00000173611.13663.97170927.19480-0.481805.524003.91730K562CPEB4
SCAIENSG00000173611.131384.253601812.25220-0.388703.310801.70290K562DDX19B
SCAIENSG00000173611.13359.43710485.56050-0.433902.805501.47470K562DDX27
SCAIENSG00000173611.13527.49510756.53710-0.520304.865903.42860K562DDX3X
SCAIENSG00000173611.13703.89350959.30360-0.446605.391004.52540K562DDX47
SCAIENSG00000173611.131412.346401729.46060-0.292203.106402.17060K562DKC1
SCAIENSG00000173611.13649.95280831.01890-0.354503.303201.97040K562EIF2S1
SCAIENSG00000173611.13331.30750571.76130-0.787208.594407.19760K562EIF3G
SCAIENSG00000173611.13557.20820711.81270-0.353302.809101.64150K562EIF4B
SCAIENSG00000173611.13380.48960588.05210-0.628105.120303.94340K562FIP1L1
SCAIENSG00000173611.13467.63940821.98980-0.8137012.5534011.35940K562FXR1
SCAIENSG00000173611.131312.06290947.130600.470102.104601.49940K562G3BP2
SCAIENSG00000173611.13402.22600658.94620-0.712206.645105.46770K562GRSF1
SCAIENSG00000173611.13640.88540866.98090-0.435903.702902.45570K562HNRNPL
SCAIENSG00000173611.13475.03790640.04310-0.430103.628902.60630K562HNRNPU
SCAIENSG00000173611.13544.44170797.25600-0.550304.579103.56130K562HSPD1
SCAIENSG00000173611.13682.46710978.86280-0.520302.919401.85690K562IGF2BP2
SCAIENSG00000173611.13656.50630995.85700-0.601102.902701.67730K562IGF2BP3
SCAIENSG00000173611.13726.307301029.29280-0.503002.812001.96490K562MAGOH
SCAIENSG00000173611.131251.967901632.76060-0.383103.223502.03720K562MAK16
SCAIENSG00000173611.13606.916301027.28780-0.759306.238804.77270K562MATR3
SCAIENSG00000173611.131355.692801910.77520-0.495106.502804.99940K562MBNL1
SCAIENSG00000173611.131267.74750915.915500.468904.571903.30860K562PCBP2
SCAIENSG00000173611.13880.619001173.39440-0.414103.712102.05810K562PNPT1
SCAIENSG00000173611.13390.15690667.57370-0.774907.761306.23400K562PPIG
SCAIENSG00000173611.13690.74700999.98160-0.533704.077003.28590K562PTBP1
SCAIENSG00000173611.131030.019801298.48890-0.334203.443602.37030K562PUM2
SCAIENSG00000173611.131054.011901593.88870-0.596707.004006.18540K562PUS1
SCAIENSG00000173611.131158.921801553.05280-0.422305.086404.30450K562RBM15
SCAIENSG00000173611.13686.51790959.16150-0.482502.359201.58870K562RBM22
SCAIENSG00000173611.13608.378201009.29420-0.730303.812302.50440K562NELFE
SCAIENSG00000173611.13687.43130962.20950-0.485104.172802.01590K562RECQL
SCAIENSG00000173611.13291.84870489.04580-0.744702.386401.62990K562RPS19
SCAIENSG00000173611.13467.70850761.71260-0.703603.131402.05830K562RPS3
SCAIENSG00000173611.13270.72360373.95400-0.466002.339601.41500K562SRFBP1
SCAIENSG00000173611.13594.09520980.25400-0.722506.078505.03830K562SRSF1
SCAIENSG00000173611.13334.54910430.10230-0.362502.042101.33600K562SYNCRIP
SCAIENSG00000173611.131385.65460929.753600.575502.787101.31760K562TAF15
SCAIENSG00000173611.13510.57020992.21320-0.958508.096506.80770K562TARDBP
SCAIENSG00000173611.13676.77150957.06690-0.500002.858602.02480K562TIA1
SCAIENSG00000173611.13588.18800716.34820-0.284402.168701.52740K562UPF1
SCAIENSG00000173611.13852.98060612.956000.476604.391103.27950K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SCAI is not available on ENCORE database.





3 RBPs can affect the splicing of SCAI :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESCAIENSG00000173611.13chr9-127828268127828337127818154127818286127904911127904956-0.195000.002470.03575excludedK562PUS1
SESCAIENSG00000173611.13chr9-1278282681278283371278181541278182861279049111279049560.548000.000010.01277includedK562KHSRP
SESCAIENSG00000173611.13chr9-127756945127757072127738392127738465127757212127757294-0.105000.003360.06784excludedK562RBM15
A3SSSCAIENSG00000173611.13chr9-1277653921277655291277653921277654941277657471277658490.059000.002140.08713longerK562PUS1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SCAI is not avaliable on ENCORE database.