PRPF19

General Information

Gene Name       : PRPF19
Gene ID             : ENSG00000110107.8
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PRPF19)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PRPF19ENSG00000110107.868.69102.6885.69ENCSR000AEF
HepG2PRPF19ENSG00000110107.8118.8289.10103.96ENCSR985KAT
K562PRPF19ENSG00000110107.8154.21142.66148.44ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PRPF19 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PRPF19 RNA is bound by 28 proteins.  







eCLIP assay for PRPF19 is not avaliable on ENCORE database.





28 proteins are bound to PRPF19 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr116065822060658271-3'-UTR,CDS,intron-Distal,polyA_signal4.507929.82364K562UPF1
chr116065849860658546-3'-UTR,intron-Distal4.761634.54659HepG2G3BP1
chr116065845260658562-3'-UTR,intron-Distal5.9685416.62098HepG2UPF1
chr116067128960671334-3'-UTR,CDS,intron-Distal,intron-Proximal3.420857.60655K562DDX3X
chr116065848760658560-3'-UTR,intron-Distal3.107023.57643HepG2FASTKD2
chr116065843860658562-3'-UTR,intron-Distal3.8393416.65864HepG2FAM120A
chr116065824760658261-3'-UTR,CDS,intron-Distal3.483868.14449K562GTF2F1
chr116065838060658503-3'-UTR,intron-Distal4.8786236.48471K562UPF1
chr116065850360658513-3'-UTR,intron-Distal7.11947400.00000K562PABPC4
chr116067119860671282-3'-UTR,CDS,intron-Distal3.0782716.36485K562YBX3
chr116067130460671328-3'-UTR,CDS,intron-Distal3.014124.77932K562YBX3
chr116065848660658564-3'-UTR,intron-Distal5.8254342.81130K562APOBEC3C
chr116065841260658497-3'-UTR,intron-Distal6.63109400.00000K562PABPC4
chr116065836260658437-3'-UTR,intron-Distal3.069114.48159HepG2LARP4
chr116065835560658373-3'-UTR,intron-Distal4.4730117.31662K562YBX3
chr116065823760658261-3'-UTR,CDS,intron-Distal4.5088313.70377K562PABPC4
chr116065837360658411-3'-UTR,intron-Distal4.5864419.18629K562YBX3
chr116065847260658545-3'-UTR,intron-Distal3.643534.32606HepG2CDC40
chr116065849060658561-3'-UTR,intron-Distal3.084024.76263K562LARP4
chr116065836660658427-3'-UTR,intron-Distal3.975053.70195HepG2UPF1
chr116065833960658433-3'-UTR,intron-Distal6.7090620.73915K562DDX6
chr116067121560671294-3'-UTR,CDS,intron-Distal4.458703.02060K562LIN28B
chr116065849960658566-3'-UTR,intron-Distal4.195196.96393HepG2PCBP2
chr116065847060658562-3'-UTR,intron-Distal4.9185534.96605K562DDX55
chr116065846960658557-3'-UTR,intron-Distal4.105383.89860HepG2PABPN1
chr116065846360658561-3'-UTR,intron-Distal3.879406.57620K562ZC3H11A
chr116065843060658563-3'-UTR,intron-Distal5.88974400.00000K562GTF2F1
chr116065853260658549-3'-UTR,intron-Distal5.76376400.00000K562PABPC4
chr116065835160658412-3'-UTR,intron-Distal4.680877.31669K562FAM120A
chr116065849460658562-3'-UTR,intron-Distal3.5676615.01304K562FASTKD2
chr116065828160658380-3'-UTR,intron-Distal4.7369715.16706K562UPF1
chr116065822360658280-3'-UTR,CDS,intron-Distal4.1546215.70119K562DDX6
chr116065843360658563-3'-UTR,intron-Distal6.3646668.38478K562DDX6
chr116065847560658560-3'-UTR,intron-Distal3.6909913.14546HepG2DDX55
chr116065841260658459-3'-UTR,intron-Distal5.0207310.04172K562FAM120A
chr116065846760658554-3'-UTR,intron-Distal4.0430134.94677K562FAM120A
chr116065821560658281-3'-UTR,CDS,intron-Distal,intron-Proximal,polyA_signal5.189927.12859K562APOBEC3C
chr116065846160658564-3'-UTR,intron-Distal6.7194525.07636HepG2PRPF4
chr116065850360658543-3'-UTR,intron-Distal5.0101835.96517K562UPF1
chr116065832760658351-3'-UTR,intron-Distal6.9223014.74338K562PABPC4
chr116065846660658563-3'-UTR,intron-Distal3.848249.19484HepG2GTF2F1
chr116065851260658548-3'-UTR,intron-Distal3.445289.02710K562TIA1
chr116065851360658532-3'-UTR,intron-Distal6.21729400.00000K562PABPC4
chr116065844160658558-3'-UTR,intron-Distal4.6997917.73058HepG2LARP4
chr116067383360673861-5'-UTR,CDS,intron-Distal3.601257.50590K562DDX3X
chr116066597260666036-CDS,intron-Distal,intron-Proximal5.350157.02967HepG2PRPF8
chr116066833860668357-CDS,intron-Distal4.354964.67689HepG2PPIG
chr116066833860668385-CDS,intron-Distal3.816485.14242HepG2G3BP1
chr116066554360665576-CDS,intron-Distal,intron-Proximal4.683714.35676HepG2PRPF8
chr116066992860669935-CDS,intron-Distal,intron-Proximal3.078763.68829K562YBX3
chr116066900560669060-CDS,intron-Distal,intron-Proximal3.110737.38503K562SF3B4
chr116066527260665328-CDS,intron-Distal,intron-Proximal4.3704219.78971HepG2PRPF8
chr116066835760668384-CDS,intron-Distal3.258644.99842HepG2PPIG
chr116066984160669905-CDS,intron-Distal,intron-Proximal4.993046.08021K562PRPF8
chr116066601260666057-CDS,intron-Distal,intron-Proximal3.606213.59112HepG2PPIG
chr116066987060669904-CDS,intron-Distal,intron-Proximal3.763555.75388HepG2BUD13
chr116067021460670250-CDS,intron-Distal,intron-Proximal3.212497.42778K562YBX3
chr116066993260669984-CDS,intron-Distal,intron-Proximal4.106604.44312HepG2EFTUD2
chr116066877660668825-CDS,intron-Distal,intron-Proximal3.745424.86632HepG2G3BP1
chr116066523460665324-CDS,intron-Distal,intron-Proximal4.0746114.99866K562PRPF8
chr116066608260666151-CDS,intron-Distal,intron-Proximal4.334457.80703K562SF3B4
chr116066876960668842-CDS,intron-Distal,intron-Proximal3.828176.00907HepG2PPIG
chr116066983260669915-CDS,intron-Distal,intron-Proximal4.676589.81400K562EFTUD2
chr116066981860669872-intron-Distal,intron-Proximal5.260145.69951K562AQR
chr116066336760663485-intron-Distal5.4164613.18638K562KHSRP
chr116066523460665315-intron-Distal,intron-Proximal4.878685.56495HepG2RBM22
chr116066794860667994-intron-Distal,intron-Proximal5.073687.13585K562PRPF8
chr116066596960665996-intron-Distal,intron-Proximal5.012856.22530K562AQR
chr116066866760668704-intron-Distal,intron-Proximal3.545394.23459K562PRPF8
chr116066599660666013-intron-Distal,intron-Proximal3.388894.88100K562AQR
chr116066580060665964-intron-Distal,intron-Proximal3.847163.46495K562TARDBP
chr116066979460669841-intron-Distal,intron-Proximal4.030826.35873K562PRPF8
chr116065873560658786-intron-Distal5.298916.90654K562SF3B4
chr116066982260669874-intron-Distal,intron-Proximal5.225115.58036HepG2EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PRPF19 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PRPF19 is not available on ENCORE database.

  • 94 RBPs can affect the levels of PRPF19.  








The Knockdown/knockout RNA-Seq assay for PRPF19 is not available on ENCORE database.





94 RBPs can affect the gene expression of PRPF19 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PRPF19ENSG00000110107.42132.248902973.70920-0.4799010.335209.14730HepG2AUH
PRPF19ENSG00000110107.41107.843801676.91750-0.598105.948004.68600HepG2BCLAF1
PRPF19ENSG00000110107.41026.155601439.63890-0.488505.998204.91970HepG2CALR
PRPF19ENSG00000110107.4894.342501499.55370-0.745609.702308.49100HepG2CPSF6
PRPF19ENSG00000110107.42313.454502683.51950-0.214102.497801.78780HepG2DAZAP1
PRPF19ENSG00000110107.41245.938801897.60600-0.606905.814004.74230HepG2DDX55
PRPF19ENSG00000110107.41018.411901428.23690-0.487907.042305.96150HepG2DNAJC21
PRPF19ENSG00000110107.41310.867501905.50670-0.539705.167704.37140HepG2EIF2S1
PRPF19ENSG00000110107.42157.805402647.80770-0.295203.593502.65920HepG2EIF4G1
PRPF19ENSG00000110107.41984.395102536.36730-0.354102.896802.06510HepG2EIF4G2
PRPF19ENSG00000110107.42661.827403414.36740-0.359206.889406.01210HepG2ETF1
PRPF19ENSG00000110107.4729.520201502.18170-1.042005.492504.06750HepG2FTO
PRPF19ENSG00000110107.41592.216101970.95480-0.307901.919101.36030HepG2G3BP1
PRPF19ENSG00000110107.41153.60020900.843700.356702.487101.64340HepG2GEMIN5
PRPF19ENSG00000110107.41351.423501699.78480-0.330902.118601.55390HepG2GPKOW
PRPF19ENSG00000110107.41415.315801696.40320-0.261402.219401.33790HepG2HDGF
PRPF19ENSG00000110107.41177.342801441.92020-0.292502.051401.48510HepG2HNRNPA1
PRPF19ENSG00000110107.41882.752502466.42790-0.389606.100304.80510HepG2HNRNPA2B1
PRPF19ENSG00000110107.41704.739002442.29370-0.5187011.5781010.24750HepG2HNRNPF
PRPF19ENSG00000110107.41028.195901622.14290-0.657807.541506.56040HepG2HNRNPLL
PRPF19ENSG00000110107.41835.090401593.277200.203802.135301.59470HepG2HNRNPU
PRPF19ENSG00000110107.41762.127102404.95190-0.448706.387705.33130HepG2IGF2BP1
PRPF19ENSG00000110107.43010.159402137.360900.493904.318303.54690HepG2MATR3
PRPF19ENSG00000110107.41038.035001654.54120-0.672604.648103.37260HepG2MTPAP
PRPF19ENSG00000110107.41105.914701394.57030-0.334602.809901.58620HepG2NAA15
PRPF19ENSG00000110107.4754.992401438.39510-0.9299013.9948012.45100HepG2NSUN2
PRPF19ENSG00000110107.41519.831801948.22490-0.358202.558901.86110HepG2PABPC4
PRPF19ENSG00000110107.41716.267201984.73150-0.209702.222101.66710HepG2PCBP1
PRPF19ENSG00000110107.41211.952801835.33020-0.5987012.5239011.05520HepG2PRPF4
PRPF19ENSG00000110107.41603.966302019.56380-0.332404.703104.03190HepG2PTBP1
PRPF19ENSG00000110107.41920.380002540.26480-0.403603.331102.68580HepG2PUF60
PRPF19ENSG00000110107.41916.223002694.68340-0.491907.259606.18990HepG2PUM2
PRPF19ENSG00000110107.41532.234901810.02250-0.240401.966701.42830HepG2PUS1
PRPF19ENSG00000110107.41809.828002187.18350-0.273202.776402.15040HepG2QKI
PRPF19ENSG00000110107.41082.138001501.36700-0.472402.174801.54370HepG2RAVER1
PRPF19ENSG00000110107.41477.253601985.03000-0.426204.852603.98200HepG2RBM25
PRPF19ENSG00000110107.41772.417802093.33440-0.240102.773302.15620HepG2RECQL
PRPF19ENSG00000110107.41596.328202631.10080-0.7209011.7400010.50400HepG2RPLP0
PRPF19ENSG00000110107.41070.119101475.57190-0.463502.493701.59580HepG2RPS10
PRPF19ENSG00000110107.41204.05090984.565400.290202.063401.52580HepG2RPS19
PRPF19ENSG00000110107.41091.092001447.81380-0.408102.884302.08370HepG2RRP9
PRPF19ENSG00000110107.41222.492501605.55710-0.393203.398202.62300HepG2SF3B1
PRPF19ENSG00000110107.41766.227502102.58120-0.251503.006002.39310HepG2SF3B4
PRPF19ENSG00000110107.41882.039702435.98930-0.372205.346204.42480HepG2SLBP
PRPF19ENSG00000110107.41116.903301786.47950-0.677604.873103.82260HepG2SNRNP70
PRPF19ENSG00000110107.42388.750803223.14730-0.4322010.711509.89980HepG2SRFBP1
PRPF19ENSG00000110107.42572.317902194.658100.229002.970602.48500HepG2SRSF1
PRPF19ENSG00000110107.41741.292002399.50800-0.462609.588708.42650HepG2SRSF7
PRPF19ENSG00000110107.41966.599602798.35760-0.5089012.7344011.79270HepG2SSB
PRPF19ENSG00000110107.41114.608801385.59260-0.314002.829401.87930HepG2SUPT6H
PRPF19ENSG00000110107.41154.864401888.97450-0.709907.891506.84410HepG2SUPV3L1
PRPF19ENSG00000110107.41448.787601972.69560-0.445306.642005.83810HepG2TAF15
PRPF19ENSG00000110107.41135.544001581.28880-0.477704.754003.83890HepG2TARDBP
PRPF19ENSG00000110107.4931.149901266.07490-0.443303.381802.28790HepG2TFIP11
PRPF19ENSG00000110107.41406.434601812.58400-0.366003.814602.84040HepG2TIA1
PRPF19ENSG00000110107.41288.190901562.00900-0.278103.380402.77110HepG2TRIM56
PRPF19ENSG00000110107.4878.905201115.83220-0.344302.346601.64600HepG2UCHL5
PRPF19ENSG00000110107.42521.415901575.226600.6786019.6880018.30770HepG2UTP3
PRPF19ENSG00000110107.4965.498501477.10590-0.613404.098602.55370HepG2XRCC5
PRPF19ENSG00000110107.41393.787701811.22320-0.378006.696105.72590HepG2ZC3H8
PRPF19ENSG00000110107.41080.145201500.74680-0.474502.990801.64040HepG2ZRANB2
PRPF19ENSG00000110107.43502.951602977.650400.234302.299701.77450K562AGGF1
PRPF19ENSG00000110107.47744.853506386.402400.278102.866501.60320K562APOBEC3C
PRPF19ENSG00000110107.43503.926404215.07150-0.266604.670603.40610K562BCLAF1
PRPF19ENSG00000110107.42137.859802880.66700-0.430204.227803.14180K562BOP1
PRPF19ENSG00000110107.42494.255703062.97510-0.296302.980302.16630K562CPSF6
PRPF19ENSG00000110107.41816.670802226.89190-0.293702.250101.31780K562DDX3X
PRPF19ENSG00000110107.47450.709305106.578900.544909.382808.26870K562DDX47
PRPF19ENSG00000110107.45286.329106069.16230-0.199202.451701.76730K562EIF2S2
PRPF19ENSG00000110107.43643.012302111.205000.7870022.5004020.20230K562EIF3G
PRPF19ENSG00000110107.41613.104802258.62560-0.485605.852503.43050K562FASTKD2
PRPF19ENSG00000110107.42255.924603116.50530-0.466205.267304.08130K562FMR1
PRPF19ENSG00000110107.41832.357502641.51980-0.527705.426604.09970K562FTO
PRPF19ENSG00000110107.41404.796901866.52640-0.410004.579502.80890K562FUS
PRPF19ENSG00000110107.44344.248602419.427900.8443029.6287027.78310K562FXR1
PRPF19ENSG00000110107.4829.353401686.85440-1.024308.669707.27470K562G3BP2
PRPF19ENSG00000110107.42400.449402924.38710-0.284802.418801.67440K562GPKOW
PRPF19ENSG00000110107.42470.640103216.94690-0.380804.554403.80740K562HNRNPC
PRPF19ENSG00000110107.43190.967802448.150700.382202.605301.41060K562HNRNPK
PRPF19ENSG00000110107.46292.929204614.520100.447504.648803.24290K562HNRNPL
PRPF19ENSG00000110107.44304.917703413.798400.334502.510001.62560K562HNRNPM
PRPF19ENSG00000110107.46186.395205113.928400.274603.738302.69840K562HNRNPU
PRPF19ENSG00000110107.41552.888002497.06280-0.685306.428104.93940K562KRR1
PRPF19ENSG00000110107.43870.059902576.710200.586705.907504.66330K562MAGOH
PRPF19ENSG00000110107.45684.631607714.63550-0.440505.094303.56730K562MSI2
PRPF19ENSG00000110107.44114.035004625.31460-0.169003.283502.47630K562NSUN2
PRPF19ENSG00000110107.43719.190605246.44240-0.496405.127803.99400K562PCBP3
PRPF19ENSG00000110107.43935.458105060.34960-0.362703.072001.42380K562PKM
PRPF19ENSG00000110107.43256.903504024.08520-0.305203.351202.46370K562POLR2G
PRPF19ENSG00000110107.42347.924602884.43290-0.296902.911201.97910K562PSIP1
PRPF19ENSG00000110107.43656.532102503.589600.546405.106704.22720K562PTBP1
PRPF19ENSG00000110107.49503.993907896.805600.267202.465801.69760K562PUF60
PRPF19ENSG00000110107.41021.439201609.25180-0.655804.014402.26990K562RAVER1
PRPF19ENSG00000110107.43412.613202399.516000.508003.843602.84170K562RBM22
PRPF19ENSG00000110107.43430.441202525.370400.441802.486401.45840K562NELFE
PRPF19ENSG00000110107.42558.882201707.752100.583302.360501.44470K562RPS3
PRPF19ENSG00000110107.42126.747702781.19720-0.387102.969801.96070K562SF3B1
PRPF19ENSG00000110107.42153.879101753.073200.297002.943102.05960K562SF3B4
PRPF19ENSG00000110107.41433.414101938.59240-0.435604.599402.41160K562SND1
PRPF19ENSG00000110107.43601.760102454.584200.553104.714003.79580K562SRSF1
PRPF19ENSG00000110107.43741.744604580.24600-0.291703.286701.62610K562SRSF9
PRPF19ENSG00000110107.43611.232604980.01780-0.463704.666302.96670K562STAU1
PRPF19ENSG00000110107.42423.036003463.74210-0.515505.099703.68260K562SUPV3L1
PRPF19ENSG00000110107.45857.609504036.421300.5371010.436708.83610K562SYNCRIP
PRPF19ENSG00000110107.41020.978101655.76640-0.697503.324901.66650K562TAF15
PRPF19ENSG00000110107.42453.499202947.86930-0.264802.112901.30210K562TRIM56
PRPF19ENSG00000110107.41249.848601687.95210-0.433504.109203.13110K562U2AF2
PRPF19ENSG00000110107.42269.694603666.10310-0.6917010.007708.02440K562UCHL5
PRPF19ENSG00000110107.43273.077104196.48330-0.358504.334303.22940K562WDR3
PRPF19ENSG00000110107.44886.349404363.677500.163102.213601.44910K562WDR43
PRPF19ENSG00000110107.45128.154606576.98680-0.359002.046601.31680K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PRPF19 is not available on ENCORE database.





2 RBPs can affect the splicing of PRPF19 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPRPF19ENSG00000110107.4chr11-606653176066542360658218606587356066557260665743-0.083000.000000.00000excludedK562SUPV3L1
A3SSPRPF19ENSG00000110107.4chr11-6066832560668525606683256066840160668766606688410.069000.000000.00000longerK562AQR
A3SSPRPF19ENSG00000110107.4chr11-6066601260666149606660126066609860666333606664030.056000.000000.00000longerK562AQR
A3SSPRPF19ENSG00000110107.4chr11-6066531760665468606653176066542360665572606657430.068000.000000.00000longerK562AQR
MXEPRPF19ENSG00000110107.4chr11-60665317606654236066557260665743606582016065873560666012606660980.113000.000480.014011includedK562SUPV3L1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PRPF19 is not avaliable on ENCORE database.