PRKAB1

General Information

Gene Name       : PRKAB1
Gene ID             : ENSG00000111725.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PRKAB1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PRKAB1ENSG00000111725.1034.6740.0237.34ENCSR000AEF
HepG2PRKAB1ENSG00000111725.1026.1626.6326.39ENCSR985KAT
K562PRKAB1ENSG00000111725.1060.0763.3661.72ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PRKAB1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PRKAB1 RNA is bound by 21 proteins.  







eCLIP assay for PRKAB1 is not avaliable on ENCORE database.





21 proteins are bound to PRKAB1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12120119177120119277+3'-UTR3.275616.98729K562FAM120A
chr12120118513120118544+3'-UTR3.149843.34573K562IGF2BP2
chr12120110057120110154+3'-UTR,5'-UTR,CDS,intron-Proximal4.6906312.81671K562SF3B4
chr12120118270120118299+3'-UTR4.3344619.13980K562IGF2BP2
chr12120119307120119376+3'-UTR4.196899.67707K562FAM120A
chr12120118244120118332+3'-UTR4.656615.71320HepG2AKAP1
chr12120119034120119114+3'-UTR4.5897829.89096K562UPF1
chr12120118604120118676+3'-UTR4.5836122.51241K562UPF1
chr12120118299120118336+3'-UTR3.448149.25001K562IGF2BP2
chr12120118561120118611+3'-UTR3.312276.56084K562IGF2BP1
chr12120119271120119312+3'-UTR5.2241514.54319K562UPF1
chr12120118936120119022+3'-UTR4.0957936.35777K562PABPC4
chr12120118363120118426+3'-UTR3.347634.79993K562IGF2BP2
chr12120118616120118682+3'-UTR4.4506911.50645K562IGF2BP1
chr12120118540120118604+3'-UTR3.5886325.15611K562UPF1
chr12120119312120119399+3'-UTR7.5657441.95525K562UPF1
chr12120110078120110119+3'-UTR,5'-UTR,CDS,intron-Proximal5.0278018.23169K562BUD13
chr12120118935120119008+3'-UTR4.7869422.86126K562UPF1
chr12120110075120110144+3'-UTR,5'-UTR,CDS,intron-Proximal3.6909210.43758K562AQR
chr12120118790120118832+3'-UTR3.4562813.19517K562UPF1
chr12120110088120110157+3'-UTR,5'-UTR,CDS,intron-Proximal4.509208.63483K562GPKOW
chr12120118871120118888+3'-UTR3.913858.24727K562UPF1
chr12120118577120118616+3'-UTR3.664715.02737K562IGF2BP2
chr12120118544120118549+3'-UTR3.7160411.05259K562YBX3
chr12120118538120118544+3'-UTR3.4343010.70078K562YBX3
chr12120118176120118259+3'-UTR3.2199910.63469K562PUM2
chr12120110120120110221+3'-UTR,5'-UTR,CDS4.580555.40397K562LIN28B
chr12120118296120118306+3'-UTR3.881688.88468K562RBM15
chr12120118247120118270+3'-UTR4.4244514.97088K562IGF2BP2
chr12120118232120118271+3'-UTR3.5768210.13110K562IGF2BP1
chr12120118346120118418+3'-UTR5.1092520.63412K562UPF1
chr12120110119120110251+3'-UTR,5'-UTR,CDS3.4637515.16774K562BUD13
chr12120118975120119026+3'-UTR3.102187.05935K562FAM120A
chr12120119178120119257+3'-UTR4.9056530.90999K562UPF1
chr12120118491120118529+3'-UTR4.1687314.60208K562UPF1
chr12120118306120118344+3'-UTR3.6558810.25633K562RBM15
chr12120118643120118692+3'-UTR3.845596.31152K562IGF2BP2
chr12120118566120118582+3'-UTR3.9309922.87458K562YBX3
chr12120118731120118790+3'-UTR3.8354316.78492K562UPF1
chr12120119026120119101+3'-UTR4.0248411.63263K562FAM120A
chr12120118494120118540+3'-UTR4.693405.80303K562IGF2BP1
chr12120118243120118389+3'-UTR5.6805912.73103HepG2UPF1
chr12120119154120119250+3'-UTR5.236119.62438K562AKAP1
chr12120119187120119252+3'-UTR3.974899.96973K562PABPC4
chr12120118549120118566+3'-UTR3.8357620.68797K562YBX3
chr12120110058120110157+3'-UTR,5'-UTR,CDS,intron-Proximal3.024354.81474HepG2BUD13
chr12120109468120109514+3'-UTR,intron-Distal,intron-Proximal5.150676.22530K562AQR
chr12120110263120110335+5'-UTR,CDS,intron-Proximal4.8443814.41880K562AQR
chr12120105880120105926+5'-UTR,intron-Proximal4.214254.84938K562DDX3X
chr12120105926120105995+5'-UTR,intron-Proximal3.215244.68144K562DDX3X
chr12120111740120111784+5'-UTR,CDS,intron-Proximal5.012856.22530K562AQR
chr12120105807120105880+5'-UTR,intron-Proximal4.085005.59242K562DDX3X
chr12120105896120106026+5'-UTR,intron-Proximal4.046794.59413K562PCBP1
chr12120111858120111907+5'-UTR,CDS,intron-Proximal4.015769.41329K562AQR
chr12120112121120112177+5'-UTR,CDS,intron-Proximal3.801195.81804K562BUD13
chr12120111748120111817+5'-UTR,CDS,intron-Proximal3.045086.12661K562BUD13
chr12120111843120111926+5'-UTR,CDS,intron-Proximal4.484167.13970HepG2PRPF8
chr12120114439120114524+CDS,intron-Proximal6.2535820.92812HepG2PRPF8
chr12120106198120106279+CDS,intron-Proximal4.4558020.49143K562PRPF8
chr12120106207120106228+CDS,intron-Proximal5.0975617.14889K562AQR
chr12120117688120117782+CDS,intron-Proximal5.1770021.16117K562SF3B4
chr12120117791120117889+CDS,intron-Proximal4.396366.23016HepG2PRPF8
chr12120114390120114468+CDS3.370355.59529K562PCBP1
chr12120117686120117746+CDS,intron-Proximal3.097563.10102HepG2SF3B4
chr12120117803120117878+CDS,intron-Proximal3.522848.69914K562AQR
chr12120117999120118085+CDS,intron-Proximal5.639319.62108K562SF3B4
chr12120118043120118102+CDS,intron-Proximal3.645649.69701K562BUD13
chr12120106183120106254+CDS,intron-Proximal5.7686716.49005HepG2PRPF8
chr12120118023120118097+CDS,intron-Proximal4.232513.25089HepG2AQR
chr12120114577120114635+intron-Distal5.6237227.78678HepG2XPO5
chr12120114525120114600+intron-Distal,intron-Proximal3.015616.58183K562EFTUD2
chr12120114522120114576+intron-Distal,intron-Proximal4.312115.26367K562AQR
chr12120114538120114577+intron-Distal,intron-Proximal3.411835.26902HepG2XPO5
chr12120112286120112380+intron-Distal,intron-Proximal3.291913.80983K562TIA1
chr12120106279120106376+intron-Distal,intron-Proximal3.1446410.11999K562PRPF8
chr12120106216120106290+intron-Proximal5.400798.70072K562RBM22
chr12120110328120110368+intron-Proximal4.015953.02181K562PRPF8
chr12120106228120106252+intron-Proximal6.9535325.56549K562AQR
chr12120112268120112322+intron-Proximal5.056137.21051K562PRPF8
chr12120111711120111756+intron-Proximal4.730164.40745K562SF3B4
chr12120114483120114522+intron-Proximal4.175177.16374K562AQR
chr12120106252120106300+intron-Proximal4.560867.92018K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PRKAB1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PRKAB1 is not available on ENCORE database.

  • 91 RBPs can affect the levels of PRKAB1.  








The Knockdown/knockout RNA-Seq assay for PRKAB1 is not available on ENCORE database.





91 RBPs can affect the gene expression of PRKAB1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PRKAB1ENSG00000111725.6473.75020580.81470-0.294002.152101.60120HepG2ACO1
PRKAB1ENSG00000111725.6849.36810615.816000.463803.180102.33730HepG2ASCC1
PRKAB1ENSG00000111725.61500.544001004.282600.5792010.727209.52260HepG2AUH
PRKAB1ENSG00000111725.6990.25870578.400400.775604.913404.14550HepG2BOP1
PRKAB1ENSG00000111725.6963.80650580.706800.7308014.4457013.17560HepG2CKAP4
PRKAB1ENSG00000111725.61079.73090580.437900.895406.699005.51130HepG2CNOT7
PRKAB1ENSG00000111725.6587.04310358.553000.711206.021204.53150HepG2CSTF2
PRKAB1ENSG00000111725.6667.39640503.883800.405403.265302.01200HepG2DDX1
PRKAB1ENSG00000111725.6670.64770438.827000.611805.686904.37670HepG2DDX24
PRKAB1ENSG00000111725.61203.98400712.932900.755907.950606.94050HepG2DDX3X
PRKAB1ENSG00000111725.6590.06630489.739500.268802.028901.45400HepG2DNAJC2
PRKAB1ENSG00000111725.6659.48740490.478900.427102.393101.53320HepG2EEF2
PRKAB1ENSG00000111725.6550.06500408.805900.428102.408301.37700HepG2EFTUD2
PRKAB1ENSG00000111725.6390.05300588.73570-0.593904.028603.32230HepG2EIF2S1
PRKAB1ENSG00000111725.6833.26730650.583400.356901.879901.34890HepG2EIF4A3
PRKAB1ENSG00000111725.6599.05300835.19560-0.479403.533502.62240HepG2EIF4G2
PRKAB1ENSG00000111725.6859.91450567.576000.599306.418005.14650HepG2EWSR1
PRKAB1ENSG00000111725.6853.19170546.852400.641604.180902.82140HepG2FUS
PRKAB1ENSG00000111725.6894.59280608.964900.554804.195703.38510HepG2G3BP1
PRKAB1ENSG00000111725.6578.44600354.451200.706505.085403.86660HepG2GEMIN5
PRKAB1ENSG00000111725.6683.25400498.816200.453803.182502.49580HepG2HNRNPA1
PRKAB1ENSG00000111725.6766.22640554.847400.465603.444502.67640HepG2HNRNPC
PRKAB1ENSG00000111725.61130.42040925.326200.288703.015302.26890HepG2HNRNPF
PRKAB1ENSG00000111725.6515.73760804.90080-0.642209.436508.26350HepG2HNRNPL
PRKAB1ENSG00000111725.6721.84240545.048600.405203.229802.21010HepG2HNRNPM
PRKAB1ENSG00000111725.6990.71340551.178600.8458017.1793015.76890HepG2HNRNPU
PRKAB1ENSG00000111725.6885.02810618.977500.515703.922503.13210HepG2IGF2BP2
PRKAB1ENSG00000111725.6854.64400656.758200.379902.247601.65420HepG2MAGOH
PRKAB1ENSG00000111725.6752.56690416.623400.853003.735002.51900HepG2METAP2
PRKAB1ENSG00000111725.6364.15990536.86480-0.560004.053502.58460HepG2NAA15
PRKAB1ENSG00000111725.61157.50910675.956000.775908.023206.97010HepG2NCBP2
PRKAB1ENSG00000111725.6708.85520876.23580-0.305802.174101.49620HepG2NOL12
PRKAB1ENSG00000111725.6918.68980524.196900.809404.318202.93410HepG2NONO
PRKAB1ENSG00000111725.6444.92080329.236200.434302.679901.46870HepG2PKM
PRKAB1ENSG00000111725.6864.85770719.143500.266102.183401.48900HepG2PRPF4
PRKAB1ENSG00000111725.6933.86120634.886200.556606.443005.67660HepG2PTBP1
PRKAB1ENSG00000111725.6815.05530591.600100.462205.629804.80660HepG2PUS1
PRKAB1ENSG00000111725.6875.97440687.605200.349202.778802.15280HepG2QKI
PRKAB1ENSG00000111725.6636.79630266.549001.256304.078001.81680HepG2RBM17
PRKAB1ENSG00000111725.61577.54530963.765200.7108013.5648012.59080HepG2RBM22
PRKAB1ENSG00000111725.6811.84050624.043000.379502.819202.13880HepG2RBM25
PRKAB1ENSG00000111725.61339.31570996.742900.426103.870503.08420HepG2RPLP0
PRKAB1ENSG00000111725.61003.63820387.428501.3731027.3114025.71170HepG2RPS19
PRKAB1ENSG00000111725.6771.25490580.720300.409302.568801.79640HepG2RPS2
PRKAB1ENSG00000111725.6777.61040592.798200.391402.376301.38580HepG2RPS5
PRKAB1ENSG00000111725.6582.81610435.494700.420302.040301.35500HepG2RRP9
PRKAB1ENSG00000111725.61270.20500697.490700.864708.058906.86430HepG2SF3A3
PRKAB1ENSG00000111725.61158.87200661.005000.8099016.0594014.81420HepG2SF3B4
PRKAB1ENSG00000111725.6539.70650249.926601.110603.104501.55210HepG2SFPQ
PRKAB1ENSG00000111725.6598.65260802.14130-0.422104.467503.60880HepG2SLBP
PRKAB1ENSG00000111725.6764.58440572.401700.417504.830704.01870HepG2SMN1
PRKAB1ENSG00000111725.61642.597501088.520800.5935012.5003011.63930HepG2SRFBP1
PRKAB1ENSG00000111725.6972.36230689.943500.494905.277104.67720HepG2SRSF1
PRKAB1ENSG00000111725.6445.32750611.78920-0.458202.281201.38240HepG2SRSF3
PRKAB1ENSG00000111725.61448.62010909.088500.6721014.3596012.99030HepG2SRSF7
PRKAB1ENSG00000111725.6356.79450561.30340-0.653707.636706.80290HepG2SRSF9
PRKAB1ENSG00000111725.61203.16900939.292700.357104.969904.17820HepG2SUCLG1
PRKAB1ENSG00000111725.6377.91620533.46590-0.497303.511702.46230HepG2SUPT6H
PRKAB1ENSG00000111725.6755.51280568.194100.411002.056601.46050HepG2SUPV3L1
PRKAB1ENSG00000111725.6503.88000380.828900.403802.220401.31770HepG2TFIP11
PRKAB1ENSG00000111725.61143.81180535.548201.0947023.0078021.82750HepG2TIAL1
PRKAB1ENSG00000111725.6415.45420540.36220-0.379203.027602.44390HepG2TRIM56
PRKAB1ENSG00000111725.61129.50550675.739500.741108.764207.64060HepG2U2AF1
PRKAB1ENSG00000111725.6578.26550267.718601.110903.359102.26810HepG2U2AF2
PRKAB1ENSG00000111725.6469.81990335.636700.485102.751801.99420HepG2UCHL5
PRKAB1ENSG00000111725.6786.01230618.565300.345502.720102.02570HepG2UPF1
PRKAB1ENSG00000111725.6906.11170597.204000.601408.548007.58860HepG2UTP3
PRKAB1ENSG00000111725.6914.09020549.365800.734505.364703.91390HepG2XRCC6
PRKAB1ENSG00000111725.6976.85410709.677800.460906.514405.55520HepG2ZC3H8
PRKAB1ENSG00000111725.6795.04130680.306600.224701.826901.35740HepG2ZNF622
PRKAB1ENSG00000111725.62342.733102999.14240-0.356406.184505.38810K562AGGF1
PRKAB1ENSG00000111725.64445.084602919.231900.606507.661606.76590K562AQR
PRKAB1ENSG00000111725.61977.696401379.407100.519705.391604.16240K562BOP1
PRKAB1ENSG00000111725.62857.466601811.175100.657703.930302.62040K562CNOT7
PRKAB1ENSG00000111725.62126.826501466.700000.536007.740806.41990K562CPSF6
PRKAB1ENSG00000111725.65637.692704275.474300.398906.121104.67820K562CELF1
PRKAB1ENSG00000111725.63134.750202588.142600.276302.756501.54640K562DDX21
PRKAB1ENSG00000111725.62340.597401877.879900.317702.769301.92040K562FIP1L1
PRKAB1ENSG00000111725.61024.386601489.89690-0.540504.979403.39130K562FKBP4
PRKAB1ENSG00000111725.61864.775101492.343100.321302.467401.65940K562FMR1
PRKAB1ENSG00000111725.62504.841302027.612800.304803.711202.39960K562GLRX3
PRKAB1ENSG00000111725.61763.035401400.333200.332202.874902.06510K562GPKOW
PRKAB1ENSG00000111725.62373.200401715.310400.468305.937605.09550K562HNRNPC
PRKAB1ENSG00000111725.61773.668902439.96800-0.460105.779504.19900K562HNRNPL
PRKAB1ENSG00000111725.62419.903601654.043300.548902.877501.42850K562ILF2
PRKAB1ENSG00000111725.61626.975302089.78360-0.361203.778802.68600K562MATR3
PRKAB1ENSG00000111725.61669.261601366.883300.288202.242301.45480K562METAP2
PRKAB1ENSG00000111725.64630.295303706.184700.321103.059601.86950K562MSI2
PRKAB1ENSG00000111725.62521.703002131.767700.242203.211402.34040K562MTPAP
PRKAB1ENSG00000111725.63290.582702368.601100.4742016.2764014.67460K562NSUN2
PRKAB1ENSG00000111725.62513.391501740.015500.530402.844501.59310K562PABPC1
PRKAB1ENSG00000111725.62405.849802034.428300.241802.069001.47930K562PTBP1
PRKAB1ENSG00000111725.62316.402601709.671700.438102.847601.50060K562RRP9
PRKAB1ENSG00000111725.63130.084602337.181300.421307.541406.24610K562SF3A3
PRKAB1ENSG00000111725.61807.398501331.782600.440503.429702.34440K562SF3B1
PRKAB1ENSG00000111725.62069.864401665.192900.313702.297501.52040K562SF3B4
PRKAB1ENSG00000111725.63604.458601623.329001.150705.943303.70860K562SFPQ
PRKAB1ENSG00000111725.63114.206502394.490600.379008.629207.07640K562SRPK2
PRKAB1ENSG00000111725.61675.466001994.39040-0.251402.036601.41950K562SRSF1
PRKAB1ENSG00000111725.63403.643102309.929000.5591012.185309.68540K562SRSF7
PRKAB1ENSG00000111725.61851.057601551.651600.254402.556601.33110K562SSB
PRKAB1ENSG00000111725.62104.215501618.926100.378102.785901.76590K562SUPV3L1
PRKAB1ENSG00000111725.62082.688001479.276800.493504.629203.39390K562TIAL1
PRKAB1ENSG00000111725.63545.697202511.476800.4974013.0805011.65690K562UPF1
PRKAB1ENSG00000111725.62789.862002148.993400.376404.308803.20640K562WDR3
PRKAB1ENSG00000111725.63128.324002234.689700.4852013.0688011.39150K562WDR43
PRKAB1ENSG00000111725.64477.178303288.436200.445105.578604.28150K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PRKAB1 is not available on ENCORE database.





13 RBPs can affect the splicing of PRKAB1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPRKAB1ENSG00000111725.6chr12+120109299120109473120105954120106208120110105120110232-0.068000.000180.07753excludedK562SMNDC1
SEPRKAB1ENSG00000111725.6chr12+1201092991201094731201059541201062081201101051201102320.336000.000470.04650includedHepG2PRPF8
SEPRKAB1ENSG00000111725.6chr12+120109299120109473120105954120106208120110105120110232-0.056000.000700.02365excludedK562AKAP8L
SEPRKAB1ENSG00000111725.6chr12+120114341120114475120110062120110269120117737120117806-0.071000.000060.00116excludedK562AQR
SEPRKAB1ENSG00000111725.6chr12+1201092991201094731201059541201062081201101051201102320.273000.000470.07182includedHepG2TIA1
SEPRKAB1ENSG00000111725.6chr12+1201092991201094731201059541201062081201101051201102320.323000.000020.00269includedHepG2FTO
SEPRKAB1ENSG00000111725.6chr12+1201092991201094731201059541201062081201101051201102320.433000.000030.00406includedHepG2HNRNPL
SEPRKAB1ENSG00000111725.6chr12+1201172371201173071201143411201144751201177371201177860.111000.000040.00564includedHepG2HNRNPL
SEPRKAB1ENSG00000111725.6chr12+1201092991201094731201059541201062081201101051201102320.237000.000080.00916includedK562HNRNPL
SEPRKAB1ENSG00000111725.6chr12+1201092991201094731201059541201062081201101051201102320.260000.000470.03813includedHepG2TIAL1
SEPRKAB1ENSG00000111725.6chr12+120109299120109473120105954120106208120110105120110232-0.073000.000010.00298excludedK562SRSF7
SEPRKAB1ENSG00000111725.6chr12+1201092991201094731201059541201062081201101051201102320.106000.000020.00179includedK562TARDBP
SEPRKAB1ENSG00000111725.6chr12+120109299120109473120105954120106208120110105120110232-0.062000.000510.02249excludedK562HNRNPU
SEPRKAB1ENSG00000111725.6chr12+120109299120109473120105954120106208120110105120110232-0.058000.002690.05865excludedK562AGGF1
MXEPRKAB1ENSG00000111725.6chr12+120106040120106208120110105120110269120105668120105850120111768120111862-0.052000.000250.064852includedK562APOBEC3C

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PRKAB1 is not avaliable on ENCORE database.