PPT2

General Information

Gene Name       : PPT2
Gene ID             : ENSG00000221988.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PPT2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PPT2ENSG00000221988.124.254.274.26ENCSR000AEF
HepG2PPT2ENSG00000221988.1236.5235.3435.93ENCSR985KAT
K562PPT2ENSG00000221988.1266.9066.4266.66ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PPT2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PPT2 RNA is bound by 27 proteins.  







eCLIP assay for PPT2 is not avaliable on ENCORE database.





27 proteins are bound to PPT2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr63213129832131399+3'-UTR,intron-Distal4.387685.14974HepG2UPF1
chr63212541632125492+3'-UTR,5'-UTR,CDS3.346563.17744HepG2GRWD1
chr63213073232130774+3'-UTR,intron-Distal3.922703.70369HepG2LIN28B
chr63213131532131393+3'-UTR,intron-Distal3.293876.72941K562FAM120A
chr63213095832130996+3'-UTR,intron-Distal3.478715.84135HepG2PCBP2
chr63213092332131006+3'-UTR,intron-Distal3.305583.50315HepG2UPF1
chr63213112732131210+3'-UTR,intron-Distal3.658859.31559HepG2PCBP2
chr63213114232131258+3'-UTR,intron-Distal3.956784.21448HepG2UPF1
chr63213390032133961+3'-UTR,5'-UTR,CDS,intron-Proximal3.250113.80334HepG2U2AF2
chr63212562632125702+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.009495.01477K562UCHL5
chr63212561832125702+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.0510619.67801K562DDX24
chr63212543332125495+3'-UTR,5'-UTR,CDS3.8595511.99628K562DDX24
chr63213091232130957+3'-UTR,intron-Distal3.814928.88820HepG2PCBP2
chr63213082832130931+3'-UTR,intron-Distal4.4088012.80402HepG2LARP4
chr63213123732131393+3'-UTR,intron-Distal4.198308.49678HepG2AKAP1
chr63212561932125706+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.7570015.53747HepG2PPIG
chr63213400832134016+3'-UTR,CDS,intron-Proximal5.317886.22530K562AQR
chr63213063432130792+3'-UTR,CDS,intron-Distal3.826517.46994HepG2RPS3
chr63212543132125496+3'-UTR,5'-UTR,CDS3.029905.08732HepG2PPIG
chr63212236432122422+5'-UTR,CDS3.610267.30480HepG2DDX3X
chr63212234332122387+5'-UTR,CDS,intron-Proximal3.342335.28960K562AQR
chr63212249132122553+5'-UTR,CDS3.322804.24070HepG2GRWD1
chr63212372732123786+5'-UTR,CDS,intron-Proximal4.065465.93840HepG2PRPF8
chr63212243032122476+5'-UTR,CDS3.714253.70637K562DDX3X
chr63212255132122603+5'-UTR,CDS,intron-Proximal5.6293212.15317HepG2PRPF8
chr63212244632122516+5'-UTR,CDS3.472484.43584K562DROSHA
chr63212199332122033+5'-UTR,intron-Distal,intron-Proximal3.341083.42371HepG2DDX3X
chr63212340132123483+5'-UTR,CDS,intron-Distal,intron-Proximal4.618725.32906HepG2AQR
chr63212250932122543+5'-UTR,CDS3.214553.43213K562UCHL5
chr63212338632123481+5'-UTR,CDS,intron-Distal,intron-Proximal3.3443812.18336K562AQR
chr63212250432122553+5'-UTR,CDS5.047588.08662K562DDX24
chr63212203332122077+5'-UTR,intron-Distal,intron-Proximal4.317785.48791HepG2DDX3X
chr63212211232122176+5'-UTR,intron-Distal,intron-Proximal3.902243.56019HepG2GRWD1
chr63212364732123680+5'-UTR,CDS,intron-Proximal3.299453.73413HepG2PPIG
chr63212375432123798+5'-UTR,CDS,intron-Proximal3.260319.68935K562AQR
chr63212567732125717+5'-UTR,CDS,intron-Distal,intron-Proximal4.184448.54394K562BUD13
chr63212568032125739+5'-UTR,CDS,intron-Distal,intron-Proximal6.2262211.46503HepG2PRPF8
chr63212271432122820+CDS,intron-Distal,intron-Proximal3.979196.08301HepG2EFTUD2
chr63213238832132448+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.5914810.18181HepG2PPIG
chr63212567932125748+5'-UTR,CDS,intron-Distal,intron-Proximal4.3933914.50379K562PRPF8
chr63212285232122905+CDS,intron-Distal3.154285.33841K562DDX24
chr63213229732132372+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.100328.17769HepG2PRPF4
chr63213034432130401+3'-UTR,CDS,intron-Proximal5.4486122.08597K562LIN28B
chr63212280632122837+CDS,intron-Distal,intron-Proximal4.578285.79396K562DDX24
chr63213058332130628+CDS,intron-Distal,intron-Proximal3.630224.36355HepG2LIN28B
chr63212282732122864+CDS,intron-Distal3.159224.39623HepG2PPIG
chr63213058232130606+CDS,intron-Distal,intron-Proximal4.531533.69113K562LIN28B
chr63213035832130408+3'-UTR,CDS,intron-Proximal4.3574612.76865HepG2PPIG
chr63213054832130589+CDS,intron-Distal,intron-Proximal3.334664.64824K562PRPF8
chr63212278532122827+CDS,intron-Distal,intron-Proximal3.384103.84119K562EFTUD2
chr63212295932123007+CDS,intron-Distal,intron-Proximal6.3451014.81397K562AQR
chr63213034432130408+3'-UTR,CDS,intron-Proximal4.0707321.08649K562DDX24
chr63212352532123561+CDS,intron-Proximal3.970446.08299HepG2PPIG
chr63213035732130400+3'-UTR,CDS,intron-Proximal3.6575311.07283HepG2LIN28B
chr63213034432130358+3'-UTR,CDS,intron-Proximal3.884415.40651HepG2PPIG
chr63213146532131569+intron-Distal3.485196.39223K562AKAP8L
chr63213221732132297+intron-Distal,intron-Proximal3.377726.96093HepG2PRPF4
chr63212260232122671+intron-Distal,intron-Proximal5.888708.93136HepG2EFTUD2
chr63213158232131675+intron-Distal4.394174.47026K562MATR3
chr63213374632133842+intron-Distal,intron-Proximal3.605383.00349HepG2ILF3
chr63213247832132622+intron-Distal,intron-Proximal3.493645.29595K562GTF2F1
chr63213363832133792+intron-Distal4.0575312.26770K562ILF3
chr63212337132123456+intron-Distal,intron-Proximal4.281644.00200K562EIF4G2
chr63213257932132673+intron-Distal3.453344.84851K562ILF3
chr63212270132122734+intron-Distal,intron-Proximal4.817064.47382K562EFTUD2
chr63212580132125885+intron-Distal3.925633.34627K562HNRNPK
chr63212296332122996+intron-Distal,intron-Proximal4.054954.58287K562PRPF8
chr63213379232133870+intron-Distal,intron-Proximal3.234047.10959K562ILF3
chr63213368532133846+intron-Distal,intron-Proximal4.574566.53376K562FUS
chr63212266932122732+intron-Distal,intron-Proximal4.619353.70058HepG2XPO5
chr63212145632121505+intron-Proximal4.474714.53454K562PRPF8
chr63213041132130481+intron-Proximal3.674688.23725K562AQR
chr63212376432123809+intron-Proximal3.694134.77019K562BUD13
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PPT2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PPT2 is not available on ENCORE database.

  • 97 RBPs can affect the levels of PPT2.  








The Knockdown/knockout RNA-Seq assay for PPT2 is not available on ENCORE database.





97 RBPs can affect the gene expression of PPT2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PPT2ENSG00000221988.8732.64810565.061900.374602.472201.45580HepG2AATF
PPT2ENSG00000221988.83353.81070860.345201.9627048.9114047.09760HepG2AKAP1
PPT2ENSG00000221988.8956.72660654.899000.546704.029302.77840HepG2AKAP8
PPT2ENSG00000221988.8405.90590711.84930-0.810407.598906.32780HepG2ASCC1
PPT2ENSG00000221988.81312.78600946.638500.471607.105506.08710HepG2AUH
PPT2ENSG00000221988.8790.75180480.155800.719605.191804.40370HepG2BOP1
PPT2ENSG00000221988.8885.96250430.399001.041508.345907.03540HepG2CNOT7
PPT2ENSG00000221988.8568.33600440.793600.366501.957501.36820HepG2CPSF6
PPT2ENSG00000221988.8946.92430746.406000.343203.160001.92670HepG2DDX1
PPT2ENSG00000221988.81823.24510824.115201.1455018.9819017.49970HepG2DDX3X
PPT2ENSG00000221988.81206.73260708.003600.769207.560206.58380HepG2DDX6
PPT2ENSG00000221988.8741.43810531.159700.481103.356502.13110HepG2EFTUD2
PPT2ENSG00000221988.8922.24040680.550000.438302.878602.27400HepG2EIF2S1
PPT2ENSG00000221988.8354.27550517.24900-0.546003.257702.28330HepG2EIF3D
PPT2ENSG00000221988.8776.982401086.88980-0.484306.453105.59800HepG2ETF1
PPT2ENSG00000221988.81191.17600755.277200.657204.692503.26390HepG2FUS
PPT2ENSG00000221988.8911.11900703.931100.372102.192101.59670HepG2G3BP1
PPT2ENSG00000221988.8427.90260640.48970-0.581902.412201.46590HepG2GNB2L1
PPT2ENSG00000221988.81022.01470712.921800.519504.468503.59850HepG2HNRNPK
PPT2ENSG00000221988.81514.60700955.992100.6638017.2752015.72310HepG2HNRNPL
PPT2ENSG00000221988.81234.97320816.463000.5969010.857509.72350HepG2HNRNPU
PPT2ENSG00000221988.81075.80230763.391800.494803.441502.74430HepG2MATR3
PPT2ENSG00000221988.81019.89310708.510000.525505.176004.09610HepG2MSI2
PPT2ENSG00000221988.81663.79970781.360201.0903016.4016014.94530HepG2NCBP2
PPT2ENSG00000221988.8967.26210808.151900.259202.201601.43770HepG2PARN
PPT2ENSG00000221988.8490.85630726.30640-0.565306.766705.88270HepG2PCBP1
PPT2ENSG00000221988.8985.92070748.356500.397603.199302.37400HepG2PRPF4
PPT2ENSG00000221988.8379.74260561.39470-0.564002.102701.39430HepG2PRPF8
PPT2ENSG00000221988.8907.07640739.057100.295402.632602.09680HepG2PTBP1
PPT2ENSG00000221988.8497.22450993.43540-0.9985015.4818014.22550HepG2PUF60
PPT2ENSG00000221988.81230.209501054.593900.222102.446601.88160HepG2PUM1
PPT2ENSG00000221988.8792.860301053.81220-0.410503.838603.05210HepG2PUM2
PPT2ENSG00000221988.81102.26830800.388900.461605.088504.28070HepG2QKI
PPT2ENSG00000221988.8426.03440689.88160-0.695403.443402.65850HepG2RAVER1
PPT2ENSG00000221988.81069.49970908.434100.235401.836401.39190HepG2RBM22
PPT2ENSG00000221988.8369.65540614.71810-0.733702.993301.88960HepG2RCC2
PPT2ENSG00000221988.8447.49910727.09320-0.7003010.427709.30090HepG2SAFB2
PPT2ENSG00000221988.8302.94430471.92460-0.639504.322303.45830HepG2SF3B1
PPT2ENSG00000221988.8554.29110769.43010-0.473104.896504.14530HepG2SF3B4
PPT2ENSG00000221988.8754.20090952.58720-0.336903.594702.81160HepG2SLBP
PPT2ENSG00000221988.8343.31150703.78690-1.035609.498707.66890HepG2SMNDC1
PPT2ENSG00000221988.81060.26370525.107601.013608.561707.19190HepG2SNRNP70
PPT2ENSG00000221988.8872.791601026.03480-0.233402.086201.63160HepG2SRFBP1
PPT2ENSG00000221988.8985.01940803.128200.294402.742002.27030HepG2SRSF1
PPT2ENSG00000221988.8420.53290653.39590-0.635708.047907.19410HepG2SRSF9
PPT2ENSG00000221988.81313.243001115.528700.235302.491301.89530HepG2SUCLG1
PPT2ENSG00000221988.8702.78910464.856000.596204.863103.93920HepG2TARDBP
PPT2ENSG00000221988.8476.82450663.30820-0.476203.852002.87370HepG2TIA1
PPT2ENSG00000221988.81002.40760800.439500.324503.469002.85310HepG2TRIM56
PPT2ENSG00000221988.8817.63580315.028101.375904.439903.17970HepG2U2AF2
PPT2ENSG00000221988.8708.623101027.35710-0.535803.627602.66170HepG2UBE2L3
PPT2ENSG00000221988.81057.60990841.246000.330103.720702.92970HepG2UPF1
PPT2ENSG00000221988.81209.82610812.191300.574809.835108.81760HepG2UTP3
PPT2ENSG00000221988.8577.14480738.57600-0.355802.561501.91080HepG2ZC3H8
PPT2ENSG00000221988.81359.49180925.210800.5551011.8709010.93520HepG2ZNF622
PPT2ENSG00000221988.8408.82900689.37300-0.753805.534603.62080HepG2ZRANB2
PPT2ENSG00000221988.8738.61760941.43580-0.350002.411601.31620K562AARS
PPT2ENSG00000221988.81716.807501219.630000.493208.287507.37800K562AGGF1
PPT2ENSG00000221988.81056.40350844.021200.323703.265901.60840K562AKAP1
PPT2ENSG00000221988.81695.358301340.072100.339202.679401.71710K562AKAP8
PPT2ENSG00000221988.81727.903501269.051500.445202.305701.70820K562AKAP8L
PPT2ENSG00000221988.8974.054501209.53210-0.312403.258802.21510K562BCLAF1
PPT2ENSG00000221988.8762.313301006.39050-0.400703.125901.75690K562CIRBP
PPT2ENSG00000221988.82254.321201742.780500.371204.522803.71670K562DDX47
PPT2ENSG00000221988.82176.241101126.139500.9504011.355108.93670K562EEF2
PPT2ENSG00000221988.81352.742301814.47070-0.423706.322905.30100K562EIF2S2
PPT2ENSG00000221988.8860.280801164.93150-0.437402.787701.74640K562EIF3D
PPT2ENSG00000221988.81021.17240741.222300.462105.385104.28780K562EIF3G
PPT2ENSG00000221988.83371.934302270.381700.5705014.1954012.17260K562EIF4G2
PPT2ENSG00000221988.8578.34190792.97970-0.455403.628201.77520K562FASTKD2
PPT2ENSG00000221988.81259.92330929.218400.439105.709204.88510K562FXR1
PPT2ENSG00000221988.8454.69610765.30320-0.751105.723304.62350K562G3BP2
PPT2ENSG00000221988.81756.016901327.801600.403205.272303.72700K562GLRX3
PPT2ENSG00000221988.81716.125301333.085800.364303.708502.46310K562HNRNPA1
PPT2ENSG00000221988.8848.954701029.99730-0.278901.880501.37670K562HNRNPC
PPT2ENSG00000221988.81292.47460919.842900.490605.171803.55010K562HNRNPF
PPT2ENSG00000221988.81296.55100937.741100.467303.819402.34340K562HNRNPK
PPT2ENSG00000221988.82225.977301574.855300.499106.190104.54450K562HNRNPL
PPT2ENSG00000221988.82399.463301476.327300.7006015.7208013.68970K562HNRNPU
PPT2ENSG00000221988.81753.615402202.99060-0.329102.622601.84700K562HSPD1
PPT2ENSG00000221988.81689.593401346.881700.327002.456201.68470K562KIF1C
PPT2ENSG00000221988.81513.97460997.580600.601707.420405.01970K562LARP7
PPT2ENSG00000221988.81638.601601044.766500.649206.320603.97020K562LIN28B
PPT2ENSG00000221988.81487.63740984.807100.595008.161006.47370K562MATR3
PPT2ENSG00000221988.81631.578601396.004400.224902.369701.62110K562MTPAP
PPT2ENSG00000221988.81414.031901057.574200.419002.374301.57120K562NAA15
PPT2ENSG00000221988.82037.865401551.119100.393608.658807.44170K562NSUN2
PPT2ENSG00000221988.81749.905701138.829500.619603.640602.20620K562PABPC1
PPT2ENSG00000221988.81415.48530783.534900.853102.688601.71540K562PABPN1
PPT2ENSG00000221988.8500.42320964.84700-0.9472015.8770012.82590K562PCBP1
PPT2ENSG00000221988.82515.218501943.875900.371602.837101.99420K562PCBP3
PPT2ENSG00000221988.81359.787301005.638700.435203.932502.19100K562PHF6
PPT2ENSG00000221988.81837.120601491.021800.301002.869802.05370K562POLR2G
PPT2ENSG00000221988.81454.443002477.24410-0.768307.479006.13490K562PUF60
PPT2ENSG00000221988.8466.15890730.17970-0.647403.301301.72500K562RAVER1
PPT2ENSG00000221988.81877.975601226.298200.6148010.633809.49650K562RBM15
PPT2ENSG00000221988.81736.404301328.528000.386203.794502.51910K562SAFB
PPT2ENSG00000221988.81566.448301079.897400.536502.975501.40040K562SBDS
PPT2ENSG00000221988.82049.482901530.509800.421105.145904.06040K562SF3A3
PPT2ENSG00000221988.81902.72290872.797101.124205.357903.29410K562SFPQ
PPT2ENSG00000221988.81123.97290798.812200.492604.607103.18840K562SRFBP1
PPT2ENSG00000221988.81834.402601568.036000.226302.740401.80820K562SRPK2
PPT2ENSG00000221988.81904.168401495.530000.348403.817202.85150K562SYNCRIP
PPT2ENSG00000221988.81332.39260888.258600.584905.588904.21520K562TIAL1
PPT2ENSG00000221988.81389.99730943.740700.558506.301304.74120K562TRIM56
PPT2ENSG00000221988.81013.25610741.766500.449903.079701.91530K562U2AF1
PPT2ENSG00000221988.8935.24300766.103300.287702.144501.43720K562U2AF2
PPT2ENSG00000221988.81354.193801644.68190-0.280402.956102.21280K562UPF1
PPT2ENSG00000221988.81834.381601415.019500.374403.876701.88050K562UPF2
PPT2ENSG00000221988.81718.611601407.306600.288202.459101.63170K562WDR3
PPT2ENSG00000221988.81864.934701463.406400.349705.710904.54020K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PPT2 is not available on ENCORE database.





13 RBPs can affect the splicing of PPT2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPPT2ENSG00000221988.8chr6+321219723212218132121217321214133212236332122554-0.493000.000020.00068excludedK562SRSF1
SEPPT2ENSG00000221988.8chr6+321219723212218132121217321214133212236332122554-0.324000.000160.01457excludedHepG2RBM22
SEPPT2ENSG00000221988.8chr6+321323553213243432130344321303993213391432133976-0.475000.003870.08681excludedK562AKAP8L
SEPPT2ENSG00000221988.8chr6+3212197232122181321212173212141332122363321225540.317000.001390.09712includedHepG2QKI
SEPPT2ENSG00000221988.8chr6+3212280632122960321223633212255432123464321235600.139000.000020.00319includedHepG2AKAP1
SEPPT2ENSG00000221988.8chr6+321219723212218132121217321214133212236332122554-0.215000.000520.00707excludedK562AQR
SEPPT2ENSG00000221988.8chr6+321219723212218132121217321214133212236332122554-0.355000.000150.02347excludedHepG2LARP4
SEPPT2ENSG00000221988.8chr6+321217753212218132121353321214133212236332122554-0.257000.001690.09305excludedK562HNRNPL
SEPPT2ENSG00000221988.8chr6+321228063212296032122363321225543212346432123560-0.269000.000030.00296excludedHepG2PCBP1
SEPPT2ENSG00000221988.8chr6+321323553213243432130344321303993213391432133976-0.464000.003560.09704excludedK562TARDBP
SEPPT2ENSG00000221988.8chr6+321323553213245832130344321303993213391432134011-0.448000.004180.07998excludedK562RBM15
SEPPT2ENSG00000221988.8chr6+321219723212218132121217321214133212236332122554-0.265000.000000.00018excludedK562ZC3H8
A3SSPPT2ENSG00000221988.8chr6+321234643212356032123544321235603212288132122960-0.156000.000000.00005shorterK562AQR
MXEPPT2ENSG00000221988.8chr6+32130583321306563213236332132458321303443213039932133914321340110.328000.000560.022611includedK562SBDS

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PPT2 is not avaliable on ENCORE database.