POLD3

General Information

Gene Name       : POLD3
Gene ID             : ENSG00000077514.8
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: POLD3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878POLD3ENSG00000077514.834.4128.5131.46ENCSR000AEF
HepG2POLD3ENSG00000077514.812.0716.8414.46ENCSR985KAT
K562POLD3ENSG00000077514.815.6216.9416.28ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for POLD3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • POLD3 RNA is bound by 7 proteins.  







eCLIP assay for POLD3 is not avaliable on ENCORE database.





7 proteins are bound to POLD3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr117435303674353113+3'-UTR,intron-Distal5.023346.10169K562LIN28B
chr117435303574353110+3'-UTR,intron-Distal4.315854.31023HepG2LIN28B
chr117430378274303914+5'-UTR,intron-Distal,intron-Proximal5.399085.16714HepG2EFTUD2
chr117430378974303905+5'-UTR,intron-Distal,intron-Proximal3.267203.20886K562PRPF8
chr117430365474303715+5'-UTR,CDS,intron-Distal3.248924.02244HepG2NCBP2
chr117433646374336569+CDS4.124263.01428K562UCHL5
chr117433692474336999+intron-Distal3.918233.69425K562TARDBP
chr117433884574338999+intron-Distal4.132514.72162K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for POLD3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for POLD3 is not available on ENCORE database.

  • 107 RBPs can affect the levels of POLD3.  








The Knockdown/knockout RNA-Seq assay for POLD3 is not available on ENCORE database.





107 RBPs can affect the gene expression of POLD3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
POLD3ENSG00000077514.4275.15160357.68450-0.378502.183501.49280HepG2AKAP8L
POLD3ENSG00000077514.4268.07000508.47400-0.9236012.0343010.78020HepG2AUH
POLD3ENSG00000077514.4150.74550360.83630-1.259209.536407.99710HepG2BCLAF1
POLD3ENSG00000077514.4162.84290306.16060-0.910806.278505.41900HepG2BOP1
POLD3ENSG00000077514.4238.35470429.59300-0.849907.761506.56120HepG2CALR
POLD3ENSG00000077514.4192.16420355.93140-0.889309.242908.16570HepG2CKAP4
POLD3ENSG00000077514.4183.54300281.06180-0.614803.142502.41500HepG2CPSF6
POLD3ENSG00000077514.4450.10000557.76270-0.309401.955901.39740HepG2CELF1
POLD3ENSG00000077514.4430.05670599.70680-0.479703.299502.50210HepG2DAZAP1
POLD3ENSG00000077514.4179.01570405.00220-1.1778012.0981010.79640HepG2DDX21
POLD3ENSG00000077514.4185.51270304.39030-0.714403.787303.06730HepG2DDX3X
POLD3ENSG00000077514.4183.39940408.21280-1.154308.125106.87880HepG2DDX55
POLD3ENSG00000077514.4171.03550371.98070-1.1209010.016008.23850HepG2DDX5
POLD3ENSG00000077514.4115.20970261.47000-1.182407.204306.24700HepG2DDX6
POLD3ENSG00000077514.4203.59250309.23440-0.603003.446002.35850HepG2DHX30
POLD3ENSG00000077514.4211.47370320.60480-0.600304.015103.18210HepG2DNAJC21
POLD3ENSG00000077514.4234.98680317.82240-0.435602.749202.10000HepG2DNAJC2
POLD3ENSG00000077514.4238.64530384.14870-0.686803.039402.07440HepG2EEF2
POLD3ENSG00000077514.4208.63420320.30560-0.618502.524001.46290HepG2EFTUD2
POLD3ENSG00000077514.4250.49500372.84730-0.573802.846201.72240HepG2AGO1
POLD3ENSG00000077514.469.64430251.36500-1.8517014.8271013.52370HepG2EIF2S1
POLD3ENSG00000077514.4193.94200277.79150-0.518402.118701.55630HepG2EIF4A3
POLD3ENSG00000077514.4248.35200566.77730-1.1904014.1831012.44530HepG2EIF4G2
POLD3ENSG00000077514.4418.75700583.81890-0.479404.264103.54540HepG2ETF1
POLD3ENSG00000077514.4237.12670385.89030-0.702505.182103.68920HepG2FASTKD2
POLD3ENSG00000077514.4197.36240277.69920-0.492702.144001.36080HepG2GEMIN5
POLD3ENSG00000077514.4297.95200436.21110-0.549903.137602.04990HepG2GNB2L1
POLD3ENSG00000077514.4144.44880323.67680-1.164009.399308.31230HepG2HNRNPA1
POLD3ENSG00000077514.4412.40700551.15980-0.418403.232302.23340HepG2HNRNPA2B1
POLD3ENSG00000077514.4188.50060360.04670-0.933606.875505.82160HepG2HNRNPC
POLD3ENSG00000077514.4236.94070371.46470-0.648705.553904.58020HepG2HNRNPF
POLD3ENSG00000077514.4147.52150304.02670-1.043307.084706.13070HepG2HNRNPLL
POLD3ENSG00000077514.4207.03150365.78410-0.821107.087905.97710HepG2IGF2BP1
POLD3ENSG00000077514.4105.48730264.28270-1.325009.556308.38660HepG2IGF2BP2
POLD3ENSG00000077514.4264.27830365.34030-0.467203.534702.71550HepG2ILF2
POLD3ENSG00000077514.4381.29850632.00540-0.729005.113003.97000HepG2LARP4
POLD3ENSG00000077514.4293.61790427.36260-0.541503.469602.19920HepG2LARP7
POLD3ENSG00000077514.4281.19200448.72050-0.674304.873703.24960HepG2LIN28B
POLD3ENSG00000077514.4442.60760281.937700.650603.750503.02580HepG2MATR3
POLD3ENSG00000077514.4274.94790386.42090-0.491002.823401.38980HepG2NIP7
POLD3ENSG00000077514.4156.66020257.00640-0.714203.576202.76170HepG2PABPC4
POLD3ENSG00000077514.4197.61850490.93340-1.3128011.504509.60250HepG2PCBP2
POLD3ENSG00000077514.495.08590315.04480-1.7283011.9275010.41780HepG2PRPF8
POLD3ENSG00000077514.4196.43890567.67090-1.5310022.8208021.32890HepG2PUF60
POLD3ENSG00000077514.4358.70890602.61580-0.7484010.609609.60820HepG2PUM1
POLD3ENSG00000077514.4362.32450602.17060-0.732907.573006.48750HepG2PUM2
POLD3ENSG00000077514.4294.94130487.95980-0.726307.026406.28990HepG2RBM22
POLD3ENSG00000077514.4407.77570289.703000.493103.200002.62670HepG2NELFE
POLD3ENSG00000077514.4378.65510269.818200.488803.131402.48110HepG2RECQL
POLD3ENSG00000077514.4162.43140400.19750-1.3009014.1612012.84060HepG2RPLP0
POLD3ENSG00000077514.4162.66420465.34420-1.5164013.5790011.66090HepG2RPS10
POLD3ENSG00000077514.4143.70860303.43820-1.078306.722205.81040HepG2RPS19
POLD3ENSG00000077514.4240.52830475.27020-0.982508.975407.59700HepG2RPS2
POLD3ENSG00000077514.4100.85190311.65840-1.6277012.5222011.04850HepG2RRP9
POLD3ENSG00000077514.4240.28010318.50710-0.406602.300901.70490HepG2SAFB2
POLD3ENSG00000077514.453.45100105.53410-0.981403.246101.83450HepG2SART3
POLD3ENSG00000077514.4186.91460304.60170-0.704502.626201.71110HepG2SERBP1
POLD3ENSG00000077514.4218.59430300.91010-0.461102.040301.42920HepG2SF3B1
POLD3ENSG00000077514.4356.96880544.32450-0.608706.510905.50820HepG2SLBP
POLD3ENSG00000077514.4277.11420482.87970-0.801205.423104.05110HepG2SMNDC1
POLD3ENSG00000077514.4289.75930460.88090-0.669503.960702.01390HepG2SND1
POLD3ENSG00000077514.4212.98620551.12430-1.3716024.1026023.00290HepG2SRFBP1
POLD3ENSG00000077514.4613.05760282.885501.1157017.3056016.33720HepG2SRSF1
POLD3ENSG00000077514.4424.72060560.50200-0.400203.079502.42330HepG2SRSF5
POLD3ENSG00000077514.4189.01710364.96080-0.949209.938208.76070HepG2SRSF7
POLD3ENSG00000077514.4164.01490230.14210-0.488702.462901.93520HepG2SRSF9
POLD3ENSG00000077514.4249.75570478.49180-0.9380012.0533011.13070HepG2SSB
POLD3ENSG00000077514.4144.17130406.41060-1.4952012.6192011.35140HepG2SUPV3L1
POLD3ENSG00000077514.4533.85420254.267401.0700014.4575013.32340HepG2TAF15
POLD3ENSG00000077514.4122.85340296.40680-1.2706010.049508.79570HepG2TARDBP
POLD3ENSG00000077514.4146.29070272.42780-0.897004.518203.29030HepG2TFIP11
POLD3ENSG00000077514.4133.71630347.47790-1.3777015.2057014.19960HepG2TIAL1
POLD3ENSG00000077514.4187.29150350.64910-0.904704.773204.07340HepG2TRIM56
POLD3ENSG00000077514.4265.84220356.61840-0.423801.867601.34050HepG2U2AF1
POLD3ENSG00000077514.4398.37280587.04790-0.559403.120602.23180HepG2UBE2L3
POLD3ENSG00000077514.4278.40190447.56210-0.684906.835005.81710HepG2UPF1
POLD3ENSG00000077514.4292.63410521.01830-0.832205.620804.14350HepG2XRCC6
POLD3ENSG00000077514.4125.07980492.23370-1.9765042.9446041.46100HepG2ZNF622
POLD3ENSG00000077514.4291.21030473.29660-0.700704.309502.66230HepG2ZRANB2
POLD3ENSG00000077514.4756.981501151.10610-0.604706.321004.48320K562ABCF1
POLD3ENSG00000077514.4864.778201071.52400-0.309302.260101.66690K562AKAP8L
POLD3ENSG00000077514.4759.923501141.36240-0.586805.514304.73520K562AQR
POLD3ENSG00000077514.4927.663101124.24520-0.277302.527401.65660K562ATP5C1
POLD3ENSG00000077514.4489.48700658.62430-0.428204.023602.84840K562BCLAF1
POLD3ENSG00000077514.4495.33410644.10880-0.378902.136601.37640K562BOP1
POLD3ENSG00000077514.4238.01450382.06000-0.682704.437703.04400K562CCAR1
POLD3ENSG00000077514.4680.415701085.56960-0.674003.946702.63440K562CNOT7
POLD3ENSG00000077514.4376.06070499.66470-0.410002.696701.65150K562CSTF2
POLD3ENSG00000077514.41367.428301958.19330-0.518107.284505.72760K562CELF1
POLD3ENSG00000077514.4610.36880775.86050-0.346103.046101.77290K562DDX21
POLD3ENSG00000077514.4426.85260562.97010-0.399302.684801.65790K562DDX3X
POLD3ENSG00000077514.4715.982201202.45410-0.7480015.1527013.74350K562DDX47
POLD3ENSG00000077514.4318.19260552.69840-0.796606.957805.45860K562EFTUD2
POLD3ENSG00000077514.4473.62420618.36840-0.384703.214901.89850K562EIF2S1
POLD3ENSG00000077514.4242.21110388.62450-0.682102.880901.85170K562EIF3A
POLD3ENSG00000077514.41267.207201592.60920-0.329703.649202.57290K562EIF4G2
POLD3ENSG00000077514.4436.88130590.60310-0.434902.540901.66850K562FTO
POLD3ENSG00000077514.4453.67640611.66400-0.431103.580802.90660K562FXR1
POLD3ENSG00000077514.4669.23670845.71030-0.337602.861701.70080K562GLRX3
POLD3ENSG00000077514.4384.24130653.92050-0.767107.795306.45810K562GPKOW
POLD3ENSG00000077514.4713.329801188.48780-0.736506.586205.41460K562GRSF1
POLD3ENSG00000077514.4568.02890812.84740-0.517005.057803.62090K562HNRNPA1
POLD3ENSG00000077514.4196.24980657.17660-1.7436016.4721015.09450K562HNRNPC
POLD3ENSG00000077514.4503.40690900.11860-0.8384013.8316011.89320K562HNRNPU
POLD3ENSG00000077514.4936.361101137.23160-0.280402.090501.38420K562KIF1C
POLD3ENSG00000077514.4286.56610558.32380-0.962207.387705.78010K562KRR1
POLD3ENSG00000077514.4635.94310799.08860-0.329502.367301.51970K562MATR3
POLD3ENSG00000077514.41086.853201697.56920-0.643307.761005.92450K562MSI2
POLD3ENSG00000077514.4637.32290987.94910-0.6324011.9076010.50820K562NSUN2
POLD3ENSG00000077514.4497.99960712.43670-0.516604.212602.99900K562PCBP2
POLD3ENSG00000077514.4412.29180537.83860-0.383501.956901.31930K562PRPF8
POLD3ENSG00000077514.4587.96990777.94050-0.403903.348502.62550K562PTBP1
POLD3ENSG00000077514.41060.115001737.66190-0.7129010.658609.04370K562PUF60
POLD3ENSG00000077514.41474.504101810.94610-0.296503.134202.11460K562PUM2
POLD3ENSG00000077514.4433.50370679.82670-0.649103.399701.79640K562RAVER1
POLD3ENSG00000077514.4308.36810547.86550-0.829206.188204.95970K562RPS19
POLD3ENSG00000077514.4619.59990974.81830-0.653809.987408.50680K562SF3A3
POLD3ENSG00000077514.4455.25360621.84220-0.449902.490001.56870K562SF3B1
POLD3ENSG00000077514.4373.40630741.02540-0.9888015.3955013.25870K562SF3B4
POLD3ENSG00000077514.4292.13180420.81660-0.526603.282601.89190K562SLBP
POLD3ENSG00000077514.41693.06210762.639901.1505027.5393025.32220K562SRSF1
POLD3ENSG00000077514.4520.20840692.40700-0.412503.852902.45620K562SRSF7
POLD3ENSG00000077514.4366.37670520.77320-0.507302.848701.81590K562SUPV3L1
POLD3ENSG00000077514.4435.07980771.84380-0.827009.150007.76020K562TARDBP
POLD3ENSG00000077514.4597.79040744.52990-0.316702.112701.40480K562TIA1
POLD3ENSG00000077514.4439.11670601.85850-0.454802.864401.89900K562TRIM56
POLD3ENSG00000077514.41183.09220713.400300.7297011.540709.88850K562U2AF2
POLD3ENSG00000077514.4359.52520551.15970-0.616404.368803.06060K562UCHL5
POLD3ENSG00000077514.4643.08480896.35120-0.479104.593103.45000K562WDR3
POLD3ENSG00000077514.4672.20900932.08020-0.471506.474105.23170K562WDR43
POLD3ENSG00000077514.4873.005501285.77500-0.558606.294504.90630K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for POLD3 is not available on ENCORE database.





1 RBPs can affect the splicing of POLD3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPOLD3ENSG00000077514.4chr11+743402617434036874336382743366187434562774345740-0.087000.004210.04035excludedK562AQR
A3SSPOLD3ENSG00000077514.4chr11+7432252774322583743225437432258374315736743158390.253000.000000.00001longerK562AQR
A5SSPOLD3ENSG00000077514.4chr11+7430364974304082743036497430376374305105743051610.079000.000110.00287longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for POLD3 is not avaliable on ENCORE database.