MTIF2

General Information

Gene Name       : MTIF2
Gene ID             : ENSG00000085760.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MTIF2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MTIF2ENSG00000085760.1436.2234.1835.20ENCSR000AEF
HepG2MTIF2ENSG00000085760.1440.6261.2250.92ENCSR985KAT
K562MTIF2ENSG00000085760.1475.3477.2076.27ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MTIF2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MTIF2 RNA is bound by 10 proteins.  







eCLIP assay for MTIF2 is not avaliable on ENCORE database.





10 proteins are bound to MTIF2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr25549630255496361-5'-UTR,intron-Distal,intron-Proximal3.033955.32471K562DDX3X
chr25549580055495871-5'-UTR,intron-Distal4.944438.66641K562YBX3
chr25549578055495876-5'-UTR,intron-Distal,intron-Proximal3.6486310.11483K562DDX3X
chr25549622755496362-5'-UTR,intron-Distal,intron-Proximal3.7425010.01011HepG2NCBP2
chr25549467655494727-5'-UTR,intron-Distal,intron-Proximal4.944594.45914HepG2PRPF8
chr25549632055496334-5'-UTR,intron-Distal,intron-Proximal3.954333.67607K562YBX3
chr25547062955470742-CDS,intron-Distal3.768307.17255K562PUM1
chr25547069755470782-CDS,intron-Distal3.790369.99051K562UCHL5
chr25547001355470090-CDS,intron-Distal,intron-Proximal3.942175.99968K562PRPF8
chr25547653055476581-CDS,intron-Distal,intron-Proximal3.251645.76422K562UCHL5
chr25547649355476562-CDS,intron-Distal,intron-Proximal4.022744.83899HepG2PRPF8
chr25547063655470688-CDS,intron-Distal3.425475.65306K562ZNF622
chr25547059855470697-CDS,intron-Distal3.251317.96329K562UCHL5
chr25547351055473580-CDS,intron-Distal5.0128712.89578HepG2BCLAF1
chr25548190155481948-CDS,intron-Distal,intron-Proximal3.144983.85381HepG2BCLAF1
chr25548112255481234-CDS,intron-Distal,intron-Proximal4.2183111.40635HepG2PRPF8
chr25547059755470645-CDS,intron-Distal5.314728.40988HepG2BCLAF1
chr25549090855490949-CDS,intron-Distal,intron-Proximal3.752666.81385HepG2BCLAF1
chr25547070055470750-CDS,intron-Distal4.042103.29312HepG2FXR2
chr25548946755489492-CDS,intron-Distal3.591705.15500HepG2BCLAF1
chr25547347655473528-CDS,intron-Distal3.628153.95301K562ZNF622
chr25546715655467174-CDS,intron-Distal4.372825.79432HepG2BCLAF1
chr25549082155490891-CDS,intron-Distal,intron-Proximal4.6832312.94366K562YBX3
chr25547652955476572-CDS,intron-Distal,intron-Proximal3.006973.73413HepG2PPIG
chr25546717455467211-CDS,intron-Distal3.770475.15500HepG2BCLAF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MTIF2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MTIF2 is not available on ENCORE database.

  • 94 RBPs can affect the levels of MTIF2.  








The Knockdown/knockout RNA-Seq assay for MTIF2 is not available on ENCORE database.





94 RBPs can affect the gene expression of MTIF2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MTIF2ENSG00000085760.10797.879201047.34460-0.392502.863001.84910HepG2ADAR
MTIF2ENSG00000085760.102100.808801449.711700.535104.506003.84900HepG2AKAP1
MTIF2ENSG00000085760.101735.390901199.579400.532605.109004.05800HepG2ASCC1
MTIF2ENSG00000085760.101598.971202149.30170-0.426707.669506.61870HepG2AUH
MTIF2ENSG00000085760.101874.365801139.662100.717709.092307.75960HepG2CIRBP
MTIF2ENSG00000085760.101333.636901121.692100.249602.870502.19670HepG2CKAP4
MTIF2ENSG00000085760.10915.312301869.09050-1.0300018.3674016.77990HepG2CPSF6
MTIF2ENSG00000085760.101485.159001752.73140-0.239003.240902.44980HepG2DAZAP1
MTIF2ENSG00000085760.101232.772701037.579100.248602.694601.87100HepG2DDX19B
MTIF2ENSG00000085760.10823.779801075.55600-0.384803.964202.59690HepG2DDX1
MTIF2ENSG00000085760.101214.80350988.333500.297602.026201.43510HepG2DDX21
MTIF2ENSG00000085760.101237.86850966.722600.356603.038402.08030HepG2DDX24
MTIF2ENSG00000085760.10852.098601054.66120-0.307702.868202.15530HepG2DNAJC21
MTIF2ENSG00000085760.101395.06500971.694900.521704.728303.57110HepG2EIF3D
MTIF2ENSG00000085760.101306.12670933.029400.485205.403603.95940HepG2EIF3G
MTIF2ENSG00000085760.101387.96670912.219800.605405.443502.86490HepG2EIF3H
MTIF2ENSG00000085760.101595.362801267.640100.331602.025701.47620HepG2EIF4A3
MTIF2ENSG00000085760.101704.896301233.925800.466302.881802.18080HepG2EIF4B
MTIF2ENSG00000085760.102206.056201729.145600.351305.173504.08600HepG2EIF4G1
MTIF2ENSG00000085760.101124.681202118.78610-0.9137012.5717011.30140HepG2GPKOW
MTIF2ENSG00000085760.10781.939201064.76430-0.445403.935903.18450HepG2HNRNPA1
MTIF2ENSG00000085760.10873.356101184.32610-0.439403.834103.02830HepG2HNRNPC
MTIF2ENSG00000085760.101280.719801684.32800-0.395205.703804.71970HepG2HNRNPF
MTIF2ENSG00000085760.101766.401701200.617400.556906.208005.19090HepG2HNRNPK
MTIF2ENSG00000085760.101205.70980995.858700.275802.147901.30950HepG2HNRNPM
MTIF2ENSG00000085760.101348.083301658.59040-0.299002.568701.87110HepG2IGF2BP1
MTIF2ENSG00000085760.101571.684501205.901600.382102.551001.90060HepG2IGF2BP2
MTIF2ENSG00000085760.10815.630101201.75850-0.5592011.278809.90760HepG2ILF2
MTIF2ENSG00000085760.101617.025301212.764600.414902.550201.59410HepG2KHSRP
MTIF2ENSG00000085760.101431.945401738.00290-0.279502.739001.97900HepG2NOL12
MTIF2ENSG00000085760.101504.549901166.060700.367605.147404.36030HepG2PCBP1
MTIF2ENSG00000085760.101357.579901659.06570-0.289302.332801.77890HepG2PUF60
MTIF2ENSG00000085760.101665.280901284.987500.373904.326803.57050HepG2QKI
MTIF2ENSG00000085760.101631.885101320.480900.305403.666403.06040HepG2NELFE
MTIF2ENSG00000085760.101452.406401229.895300.239802.411601.83090HepG2RECQL
MTIF2ENSG00000085760.102273.412901814.311400.325302.852002.15980HepG2RPLP0
MTIF2ENSG00000085760.101454.197401235.287100.235302.307601.76080HepG2SF3B4
MTIF2ENSG00000085760.101322.291801590.76070-0.266703.467402.69680HepG2SLBP
MTIF2ENSG00000085760.101038.320101903.33220-0.874302.799001.48290HepG2SNRNP200
MTIF2ENSG00000085760.101936.477402329.55670-0.266603.782603.22470HepG2SRFBP1
MTIF2ENSG00000085760.101790.887701289.395100.473908.687407.95530HepG2SRSF1
MTIF2ENSG00000085760.101403.070501638.07130-0.223402.296101.71890HepG2SRSF5
MTIF2ENSG00000085760.101167.527701654.76830-0.503208.758507.63810HepG2SRSF7
MTIF2ENSG00000085760.101443.739501049.011100.460707.858107.01300HepG2SRSF9
MTIF2ENSG00000085760.101869.430801159.021600.6896014.2231013.09760HepG2TAF15
MTIF2ENSG00000085760.10740.169901970.74840-1.4128033.7285031.74510HepG2TARDBP
MTIF2ENSG00000085760.10884.211501153.40040-0.383404.945404.23560HepG2TRIM56
MTIF2ENSG00000085760.101179.148002216.84630-0.910802.779001.78680HepG2U2AF2
MTIF2ENSG00000085760.101438.470901197.939000.263903.011802.28950HepG2UPF1
MTIF2ENSG00000085760.101600.480301156.562300.468607.969707.03720HepG2UTP3
MTIF2ENSG00000085760.103157.299203807.40870-0.270104.358603.67540K562AGGF1
MTIF2ENSG00000085760.103056.148103961.74370-0.374404.081003.28580K562AKAP8L
MTIF2ENSG00000085760.102543.903704747.19810-0.9000019.0105017.63870K562AQR
MTIF2ENSG00000085760.102220.538602704.73270-0.284603.597002.05290K562BCCIP
MTIF2ENSG00000085760.102137.077302613.76060-0.290504.436703.20130K562BCLAF1
MTIF2ENSG00000085760.102609.610503400.62770-0.382003.139801.60640K562BUD13
MTIF2ENSG00000085760.10786.175201187.23320-0.594706.116404.38080K562CCAR1
MTIF2ENSG00000085760.103694.680705904.53080-0.676403.665202.41170K562CNOT7
MTIF2ENSG00000085760.101903.213103232.85120-0.7644016.6365014.69020K562CPSF6
MTIF2ENSG00000085760.101639.170601982.92690-0.274702.768001.71220K562CSTF2
MTIF2ENSG00000085760.102557.477003071.50290-0.264203.660802.26770K562DDX21
MTIF2ENSG00000085760.101718.378702123.00580-0.305103.648102.09020K562DDX6
MTIF2ENSG00000085760.105102.349504263.355700.259103.388702.40610K562DKC1
MTIF2ENSG00000085760.101515.199802244.89450-0.567103.758702.68210K562EFTUD2
MTIF2ENSG00000085760.102378.605303424.65190-0.5258011.5171010.19880K562EIF2S2
MTIF2ENSG00000085760.102931.280603509.43810-0.259702.065301.32850K562FIP1L1
MTIF2ENSG00000085760.102227.935903289.28060-0.562107.236205.81850K562FMR1
MTIF2ENSG00000085760.102235.559802787.93220-0.318602.424501.57290K562FTO
MTIF2ENSG00000085760.102712.116902275.064100.253402.963902.34090K562FXR1
MTIF2ENSG00000085760.103302.745902507.537800.397302.575801.89830K562G3BP2
MTIF2ENSG00000085760.101930.686803086.60570-0.6769011.341209.71060K562GPKOW
MTIF2ENSG00000085760.103190.869404563.74810-0.516308.125006.81760K562GRSF1
MTIF2ENSG00000085760.101545.779502353.30280-0.606404.045503.34070K562HNRNPC
MTIF2ENSG00000085760.104367.486603086.094000.500905.476203.67650K562HNRNPK
MTIF2ENSG00000085760.102891.974803446.81610-0.253202.927402.00890K562HNRNPU
MTIF2ENSG00000085760.105731.377504758.068500.268402.208701.49570K562HSPD1
MTIF2ENSG00000085760.102377.662103089.42650-0.377802.631301.63960K562IGF2BP2
MTIF2ENSG00000085760.102588.166803240.75220-0.324403.454902.40920K562MATR3
MTIF2ENSG00000085760.102065.944003012.85960-0.544308.039706.50320K562METAP2
MTIF2ENSG00000085760.102597.600903431.37410-0.401608.735307.37350K562MTPAP
MTIF2ENSG00000085760.103066.821303812.65870-0.314108.548407.33880K562NSUN2
MTIF2ENSG00000085760.102337.787402889.34780-0.305602.873901.87720K562PCBP2
MTIF2ENSG00000085760.102208.075402915.29020-0.400903.354602.43920K562PCBP3
MTIF2ENSG00000085760.101654.183302236.15540-0.434905.795004.63950K562POLR2G
MTIF2ENSG00000085760.105110.923206714.79040-0.393807.389105.79700K562PUM2
MTIF2ENSG00000085760.103103.265103828.22140-0.302904.056903.35570K562RBM15
MTIF2ENSG00000085760.102485.017903025.39960-0.283902.327501.56160K562RBM22
MTIF2ENSG00000085760.103466.126205377.84570-0.633703.134601.50270K562SBDS
MTIF2ENSG00000085760.102907.242703761.98140-0.371806.330205.13600K562SF3A3
MTIF2ENSG00000085760.102357.231502935.36810-0.316402.185301.33180K562SF3B1
MTIF2ENSG00000085760.101253.432101824.28050-0.541403.815002.55370K562SRFBP1
MTIF2ENSG00000085760.103138.056903854.21860-0.296606.233804.89370K562SRPK2
MTIF2ENSG00000085760.102040.438603092.81020-0.6000010.261308.91300K562SRSF1
MTIF2ENSG00000085760.101565.341602099.35100-0.423504.848603.39520K562SRSF4
MTIF2ENSG00000085760.102151.475102741.15430-0.349505.526103.85950K562SRSF7
MTIF2ENSG00000085760.104593.163505621.66010-0.291503.288001.65260K562SUCLG1
MTIF2ENSG00000085760.102786.978402242.882900.313203.523702.59700K562SYNCRIP
MTIF2ENSG00000085760.102214.817603130.22520-0.499105.566404.54460K562TARDBP
MTIF2ENSG00000085760.102421.177803019.42950-0.318603.468402.53690K562TIA1
MTIF2ENSG00000085760.101512.066702029.40060-0.424502.563401.66610K562TIAL1
MTIF2ENSG00000085760.101455.330502155.26810-0.566504.110602.91020K562TRIM56
MTIF2ENSG00000085760.101641.915102238.88440-0.447403.003501.93440K562UCHL5
MTIF2ENSG00000085760.102856.277004042.63540-0.5012013.9807012.51800K562UPF1
MTIF2ENSG00000085760.103121.164403991.61400-0.354902.719601.52970K562UTP3
MTIF2ENSG00000085760.102712.297403459.16750-0.350904.027502.96600K562WDR3
MTIF2ENSG00000085760.104430.918205624.39040-0.344103.968802.41190K562WRN
MTIF2ENSG00000085760.104119.460605347.95740-0.376504.276003.16570K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MTIF2 is not available on ENCORE database.





15 RBPs can affect the splicing of MTIF2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMTIF2ENSG00000085760.10chr2-554957135549587555494704554947715549630455496384-0.419000.000000.00000excludedK562SRSF1
SEMTIF2ENSG00000085760.10chr2-554644235546452855463757554639565546714655467311-0.063000.001500.02921excludedK562SF3B4
SEMTIF2ENSG00000085760.10chr2-554935165549365455490893554910015549470455494771-0.073000.000000.00030excludedK562PRPF8
SEMTIF2ENSG00000085760.10chr2-554796125547978955476530554766705548117655481337-0.147000.006270.09024excludedHepG2U2AF1
SEMTIF2ENSG00000085760.10chr2-554957855549587555494704554947715549630455496384-0.079000.000310.00450excludedK562AQR
SEMTIF2ENSG00000085760.10chr2-554644235546459855463757554639565546714655467311-0.069000.000010.00028excludedK562AQR
SEMTIF2ENSG00000085760.10chr2-554957135549587555494704554947715549595255496315-0.126000.000410.01935excludedK562FXR1
SEMTIF2ENSG00000085760.10chr2-5549173755491846554908935549100155494704554947710.051000.000100.06231includedHepG2LIN28B
SEMTIF2ENSG00000085760.10chr2-554935165549365455490893554910015549470455494771-0.087000.000000.00000excludedK562EFTUD2
SEMTIF2ENSG00000085760.10chr2-5549351655493654554908935549100155494704554947710.069000.000440.07848includedK562SBDS
SEMTIF2ENSG00000085760.10chr2-554957135549587555494704554947715549630455496384-0.140000.000140.00501excludedHepG2SRSF1
SEMTIF2ENSG00000085760.10chr2-5549351655493654554907755549100155494704554947710.064000.000220.06012includedHepG2NOL12
SEMTIF2ENSG00000085760.10chr2-554935165549365455490893554910015549470455494771-0.052000.001890.04430excludedK562RBM15
SEMTIF2ENSG00000085760.10chr2-5549351655493654554908935549100155494704554947710.137000.000040.00305includedHepG2HNRNPC
SEMTIF2ENSG00000085760.10chr2-554957135549587555494704554947715549595255496315-0.099000.000230.01272excludedK562PTBP1
SEMTIF2ENSG00000085760.10chr2-5549351655493654554908935549100155494704554947710.205000.000000.00000includedK562HNRNPC
A3SSMTIF2ENSG00000085760.10chr2-5546442355464633554644235546456455467146554673110.099000.000000.00000longerK562AQR
A5SSMTIF2ENSG00000085760.10chr2-554957135549587555495785554958755549470455494771-0.162000.000070.01410shorterK562RBM22
A5SSMTIF2ENSG00000085760.10chr2-554957135549587555495785554958755549470455494771-0.213000.000010.00166shorterHepG2RBM22
A5SSMTIF2ENSG00000085760.10chr2-554957135549587555495785554958755549470455494771-0.377000.000000.00000shorterHepG2SRSF1
A5SSMTIF2ENSG00000085760.10chr2-554957135549587555495785554958755549470455494771-0.336000.000000.00000shorterK562SRSF1
MXEMTIF2ENSG00000085760.10chr2-55490775554910015549470455494771554894515548956355495713554958750.128000.001090.035921includedK562UCHL5
MXEMTIF2ENSG00000085760.10chr2-5549173755491846554935165549365455490775554910015549470455494771-0.512000.005240.080122includedHepG2SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MTIF2 is not avaliable on ENCORE database.