IPO8

General Information

Gene Name       : IPO8
Gene ID             : ENSG00000133704.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: IPO8)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878IPO8ENSG00000133704.922.0220.2721.14ENCSR000AEF
HepG2IPO8ENSG00000133704.917.9017.6317.77ENCSR985KAT
K562IPO8ENSG00000133704.919.1019.6019.35ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for IPO8 is not avaliable on ENCORE database.



Proteins bound to RNA
  • IPO8 RNA is bound by 15 proteins.  







eCLIP assay for IPO8 is not avaliable on ENCORE database.





15 proteins are bound to IPO8 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr123078371430783824-3'-UTR,CDS,intron-Distal3.015064.19577K562UCHL5
chr123078373830783844-3'-UTR,CDS,intron-Distal3.975845.14848K562ZNF622
chr123078297530783029-3'-UTR,intron-Distal3.176464.61367K562UPF1
chr123078199930782078-3'-UTR,intron-Distal3.770807.50442K562UPF1
chr123078361330783654-3'-UTR,intron-Distal3.145817.24994K562YBX3
chr123078262530782709-3'-UTR,intron-Distal3.134446.65594K562UPF1
chr123078318130783230-3'-UTR,intron-Distal4.800108.44976K562PUM2
chr123084859230848620-5'-UTR,intron-Distal3.257164.34695HepG2BCLAF1
chr123084863730848694-5'-UTR,intron-Distal3.780619.01874HepG2BCLAF1
chr123084857730848707-5'-UTR,CDS,intron-Distal5.935418.32974K562DDX24
chr123084858430848710-5'-UTR,intron-Distal3.845456.65823HepG2PRPF4
chr123084861630848688-5'-UTR,intron-Distal5.231778.43384K562UCHL5
chr123084871030848784-5'-UTR,intron-Distal3.156643.03570HepG2NCBP2
chr123079009530790117-CDS,intron-Distal,intron-Proximal3.791074.09885HepG2BCLAF1
chr123078993630790012-CDS,intron-Distal4.108826.86842HepG2U2AF2
chr123081912730819171-CDS,intron-Distal3.445385.15776HepG2BCLAF1
chr123082214730822171-CDS,intron-Distal,intron-Proximal3.602543.68471HepG2BCLAF1
chr123080597630806019-CDS,intron-Distal4.099415.94293HepG2BCLAF1
chr123081656630816589-CDS,intron-Distal,intron-Proximal5.438449.78817HepG2BCLAF1
chr123082762330827685-CDS,intron-Distal4.031184.04622HepG2GRWD1
chr123078706830787149-CDS,intron-Distal5.5886610.17900K562ZNF622
chr123078704830787203-CDS,intron-Distal4.4658420.00439K562UCHL5
chr123081412830814174-CDS,intron-Distal4.130116.23296HepG2BCLAF1
chr123078705730787138-CDS,intron-Distal3.800039.08790HepG2BCLAF1
chr123082759730827668-CDS,intron-Distal4.345844.21675K562ZNF622
chr123080965330809684-CDS,intron-Distal3.554105.97823HepG2BCLAF1
chr123081815230818188-CDS,intron-Distal,intron-Proximal5.8376212.88829HepG2BCLAF1
chr123084840330848471-intron-Distal5.148976.19887HepG2RBM22
chr123080016630800227-intron-Distal4.346054.48623K562EXOSC5
chr123078498530785163-intron-Distal,intron-Proximal4.642154.96658K562KHSRP
chr123082029130820346-intron-Distal4.095253.83958HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for IPO8 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for IPO8 is not available on ENCORE database.

  • 93 RBPs can affect the levels of IPO8.  








The Knockdown/knockout RNA-Seq assay for IPO8 is not available on ENCORE database.





93 RBPs can affect the gene expression of IPO8 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
IPO8ENSG00000133704.51066.347701239.07450-0.216602.074501.53320HepG2ACO1
IPO8ENSG00000133704.5748.66470981.99690-0.391402.788901.78920HepG2ADAR
IPO8ENSG00000133704.51182.343001725.90850-0.545704.372703.72480HepG2AKAP1
IPO8ENSG00000133704.51110.198501428.06240-0.363202.506801.75570HepG2ASCC1
IPO8ENSG00000133704.51555.371201790.37070-0.203002.061201.45220HepG2AUH
IPO8ENSG00000133704.5644.439601099.31810-0.770506.485905.02220HepG2BCCIP
IPO8ENSG00000133704.5670.43380955.30240-0.510903.282402.30360HepG2BCLAF1
IPO8ENSG00000133704.51023.412201662.63240-0.700106.133804.65000HepG2CCAR1
IPO8ENSG00000133704.51560.257801238.677600.332905.077604.22720HepG2CKAP4
IPO8ENSG00000133704.51008.965801436.39740-0.509608.056907.06760HepG2CELF1
IPO8ENSG00000133704.51153.786701544.56380-0.420807.652506.50810HepG2DAZAP1
IPO8ENSG00000133704.51465.488501145.907800.354805.506904.38230HepG2DDX19B
IPO8ENSG00000133704.51314.986501011.392600.378602.574101.33190HepG2DDX27
IPO8ENSG00000133704.51238.923101653.32860-0.416303.134302.47330HepG2DDX3X
IPO8ENSG00000133704.5595.776501080.81590-0.859307.981406.74650HepG2DDX55
IPO8ENSG00000133704.51659.259501156.871500.520205.287403.93150HepG2DDX5
IPO8ENSG00000133704.5892.990101420.15210-0.669306.123205.23300HepG2DDX6
IPO8ENSG00000133704.51514.805001185.425600.353604.617903.78230HepG2DKC1
IPO8ENSG00000133704.5843.14600980.06010-0.217101.972301.40470HepG2DNAJC2
IPO8ENSG00000133704.5977.880801365.31730-0.481503.880703.18550HepG2EIF2S1
IPO8ENSG00000133704.51041.722001469.02270-0.495903.032802.31550HepG2EIF4B
IPO8ENSG00000133704.51936.839701459.653300.408003.633402.70720HepG2EIF4G2
IPO8ENSG00000133704.5640.209101026.41110-0.681002.631301.64160HepG2FTO
IPO8ENSG00000133704.5799.397301419.45790-0.8284019.1031017.08970HepG2HNRNPA2B1
IPO8ENSG00000133704.5847.379901110.42850-0.390003.075202.34920HepG2HNRNPC
IPO8ENSG00000133704.5916.376201429.81030-0.641807.292806.19870HepG2HNRNPK
IPO8ENSG00000133704.51368.449601108.442000.303901.958001.42060HepG2HNRNPLL
IPO8ENSG00000133704.5798.181101126.77140-0.497408.728607.49780HepG2ILF2
IPO8ENSG00000133704.51362.114101754.95960-0.365602.117601.39900HepG2LARP4
IPO8ENSG00000133704.5901.942901531.58180-0.7639014.9099013.20140HepG2NOL12
IPO8ENSG00000133704.5863.108001091.89170-0.339203.634302.67690HepG2PARN
IPO8ENSG00000133704.51104.78690909.465500.280602.624001.86790HepG2PRPF4
IPO8ENSG00000133704.5973.373801462.00550-0.586907.455306.53840HepG2PUF60
IPO8ENSG00000133704.51187.482201550.83950-0.385104.282603.45880HepG2PUM2
IPO8ENSG00000133704.51820.335301480.015400.298503.054702.40410HepG2QKI
IPO8ENSG00000133704.51231.420401491.18370-0.276102.308801.51690HepG2RBM15
IPO8ENSG00000133704.51289.050701718.07630-0.414505.763505.08410HepG2RBM22
IPO8ENSG00000133704.51005.906501370.63520-0.446303.466302.34970HepG2RBM27
IPO8ENSG00000133704.51349.113701097.130400.298202.002101.39680HepG2SF3B1
IPO8ENSG00000133704.5943.959101145.61600-0.279303.221402.53590HepG2SMN1
IPO8ENSG00000133704.5841.604601220.75290-0.536602.965002.15460HepG2SNRNP70
IPO8ENSG00000133704.51598.966501940.51130-0.279303.545503.00020HepG2SRFBP1
IPO8ENSG00000133704.5814.523301051.56700-0.368504.177903.34870HepG2SRSF7
IPO8ENSG00000133704.51395.225001208.211500.207502.055501.56520HepG2SRSF9
IPO8ENSG00000133704.52255.697901684.836000.420908.170207.37840HepG2SSB
IPO8ENSG00000133704.5688.72930893.01250-0.374702.731001.79530HepG2SUPT6H
IPO8ENSG00000133704.52129.257001334.906000.6735014.4244013.29180HepG2TAF15
IPO8ENSG00000133704.5773.414201071.92580-0.470905.203004.56190HepG2TIAL1
IPO8ENSG00000133704.5758.733601081.43360-0.511307.800406.93190HepG2TRIM56
IPO8ENSG00000133704.5630.126501131.29220-0.8443010.426309.18790HepG2U2AF1
IPO8ENSG00000133704.5332.716401375.80650-2.0479010.473608.45520HepG2U2AF2
IPO8ENSG00000133704.5614.20860985.46370-0.682104.062402.83590HepG2UPF2
IPO8ENSG00000133704.5891.743601138.24950-0.352103.924503.22980HepG2UTP3
IPO8ENSG00000133704.5812.341101059.20400-0.382802.088901.45100HepG2XRN2
IPO8ENSG00000133704.51002.028601296.64200-0.371905.739305.02610HepG2ZNF622
IPO8ENSG00000133704.51586.481601884.27880-0.248202.891602.31260K562AGGF1
IPO8ENSG00000133704.51084.787302680.92100-1.3053032.6966030.88120K562AQR
IPO8ENSG00000133704.51231.985201666.94090-0.436207.360605.76840K562BCLAF1
IPO8ENSG00000133704.5500.40360772.74150-0.626905.978504.27350K562CCAR1
IPO8ENSG00000133704.51058.944301381.53680-0.383603.646202.74710K562CPSF6
IPO8ENSG00000133704.5951.800001264.62320-0.410004.473903.09000K562CSTF2
IPO8ENSG00000133704.53471.466104141.33020-0.254502.596601.65220K562CELF1
IPO8ENSG00000133704.51238.240501525.05240-0.300602.542501.54540K562DDX3X
IPO8ENSG00000133704.5632.08080865.06010-0.452703.327001.85520K562DHX30
IPO8ENSG00000133704.51063.516701414.74300-0.411703.170902.18880K562EFTUD2
IPO8ENSG00000133704.51321.487101675.12550-0.342104.537102.96360K562EIF2S1
IPO8ENSG00000133704.51532.274402028.31500-0.404605.950404.95540K562EIF2S2
IPO8ENSG00000133704.51030.680701593.29850-0.628408.144506.73990K562EIF4A3
IPO8ENSG00000133704.51025.402901434.84710-0.484706.746504.81600K562EIF4B
IPO8ENSG00000133704.51131.631701405.69700-0.312902.234201.46360K562FMR1
IPO8ENSG00000133704.5774.750501191.46200-0.620906.045804.63930K562FTO
IPO8ENSG00000133704.52145.068801588.719800.433102.835302.11650K562G3BP2
IPO8ENSG00000133704.5890.538601418.36250-0.671507.002804.74170K562GEMIN5
IPO8ENSG00000133704.5909.333101319.02100-0.536605.824904.67680K562GPKOW
IPO8ENSG00000133704.51680.518602703.06530-0.6857011.8096010.22350K562GRSF1
IPO8ENSG00000133704.5814.700001393.31180-0.7742011.8545010.69310K562HNRNPC
IPO8ENSG00000133704.51589.954602030.49270-0.352803.215001.90340K562IGF2BP3
IPO8ENSG00000133704.51045.853001413.04550-0.434103.429201.75870K562LIN28B
IPO8ENSG00000133704.51604.281902098.18740-0.387203.926202.91720K562MAGOH
IPO8ENSG00000133704.51606.657602093.97520-0.382204.182703.03040K562MATR3
IPO8ENSG00000133704.51036.231101287.51450-0.313202.378901.56920K562METAP2
IPO8ENSG00000133704.52885.646003590.25790-0.315202.577301.48940K562MSI2
IPO8ENSG00000133704.51528.849401933.18820-0.338505.092804.01890K562MTPAP
IPO8ENSG00000133704.51670.115802147.89070-0.363007.770306.60730K562NSUN2
IPO8ENSG00000133704.51002.883601371.78370-0.451903.714401.96730K562NUSAP1
IPO8ENSG00000133704.5996.343201360.27240-0.449204.122102.32390K562PHF6
IPO8ENSG00000133704.51543.135602121.96430-0.459504.787103.66230K562PPIG
IPO8ENSG00000133704.5645.781701249.23820-0.9519015.2625012.79710K562PSIP1
IPO8ENSG00000133704.52599.348203675.04750-0.499606.053104.84880K562PUF60
IPO8ENSG00000133704.53109.079703830.04320-0.300904.086902.91270K562PUM2
IPO8ENSG00000133704.51216.536701954.83610-0.684309.786908.05250K562RBM22
IPO8ENSG00000133704.5786.192601139.71140-0.535706.149904.66830K562RCC2
IPO8ENSG00000133704.51416.323302057.11510-0.538505.823104.15560K562NELFE
IPO8ENSG00000133704.51014.200701402.41330-0.467603.310102.41400K562RPS19
IPO8ENSG00000133704.51006.383101407.71530-0.484202.978401.59570K562RRP9
IPO8ENSG00000133704.51627.128102119.50180-0.381405.375404.26690K562SF3A3
IPO8ENSG00000133704.5753.255401080.42180-0.520404.801103.33730K562SRFBP1
IPO8ENSG00000133704.5712.47560934.86790-0.391903.055001.93620K562SRSF4
IPO8ENSG00000133704.51390.972901887.23420-0.440204.408803.03150K562SRSF5
IPO8ENSG00000133704.51187.964201451.22090-0.288803.258701.98090K562SRSF7
IPO8ENSG00000133704.51016.214601333.09880-0.391602.553301.58150K562SUPV3L1
IPO8ENSG00000133704.51320.830302022.55700-0.614707.434006.21180K562TARDBP
IPO8ENSG00000133704.51509.764201950.96610-0.369903.937502.93780K562TIA1
IPO8ENSG00000133704.5805.157001201.56510-0.577605.207203.88000K562TIAL1
IPO8ENSG00000133704.5924.976901276.44430-0.464604.238103.01100K562TRIM56
IPO8ENSG00000133704.51007.773101591.08040-0.6588010.639709.06010K562U2AF2
IPO8ENSG00000133704.51778.456702277.45840-0.356805.988104.97730K562UPF1
IPO8ENSG00000133704.51492.019001948.74210-0.385304.116803.04170K562WDR3
IPO8ENSG00000133704.51102.484501436.51590-0.381802.796501.58310K562XRN2
IPO8ENSG00000133704.52324.767803020.24080-0.377603.984402.91660K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for IPO8 is not available on ENCORE database.





4 RBPs can affect the splicing of IPO8 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEIPO8ENSG00000133704.5chr12-308345923083475130833415308335723083723430837391-0.135000.000110.00365excludedK562U2AF1
SEIPO8ENSG00000133704.5chr12-308434293084348230837234308373913084849730848803-0.172000.001890.05480excludedK562UTP18
SEIPO8ENSG00000133704.5chr12-308345923083475130833415308335723083723430837391-0.094000.002350.03975excludedK562U2AF2
A3SSIPO8ENSG00000133704.5chr12-3078482830784985307848283078494530787016307872200.247000.000000.00000longerK562AQR
A3SSIPO8ENSG00000133704.5chr12-3083723430837474308372343083739130843429308435110.085000.000030.00030longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for IPO8 is not avaliable on ENCORE database.