ILK

General Information

Gene Name       : ILK
Gene ID             : ENSG00000166333.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ILK)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ILKENSG00000166333.1370.3073.7472.02ENCSR000AEF
HepG2ILKENSG00000166333.1386.8569.8978.37ENCSR985KAT
K562ILKENSG00000166333.1360.3958.4559.42ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ILK is not avaliable on ENCORE database.



Proteins bound to RNA
  • ILK RNA is bound by 18 proteins.  







eCLIP assay for ILK is not avaliable on ENCORE database.





18 proteins are bound to ILK RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1166299626629999+3'-UTR,CDS,intron-Distal3.022404.14618K562ZNF622
chr1166318866632011+3'-UTR3.110554.45691HepG2LARP4
chr1166305316630604+3'-UTR,CDS,intron-Distal4.135434.15726HepG2G3BP1
chr1166300646630135+3'-UTR,CDS,intron-Distal,intron-Proximal4.5202316.21903K562SF3B4
chr1166295946629641+3'-UTR,CDS,intron-Proximal4.768386.99120K562AQR
chr1166295976629688+3'-UTR,CDS,intron-Proximal3.490788.89076K562BUD13
chr1166309916631126+3'-UTR,CDS,intron-Distal,intron-Proximal4.209027.99161HepG2PRPF8
chr1166303016630351+3'-UTR,CDS,intron-Distal,intron-Proximal4.204194.25741HepG2G3BP1
chr1166301986630246+3'-UTR,CDS,intron-Distal,intron-Proximal5.560867.81430K562AQR
chr1166319376632025+3'-UTR3.958025.75237K562PCBP1
chr1166296556629724+3'-UTR,CDS,intron-Proximal3.199324.34780K562ZNF622
chr1166304826630555+3'-UTR,CDS,intron-Distal,intron-Proximal4.2716918.06218K562SF3B4
chr1166318546632089+3'-UTR4.367994.13104K562APOBEC3C
chr1166295546629651+3'-UTR,CDS,intron-Proximal4.933208.52172K562GPKOW
chr1166307516630820+3'-UTR,CDS,intron-Distal4.261633.68241HepG2G3BP1
chr1166320116632073+3'-UTR3.673414.63830HepG2LARP4
chr1166302286630271+3'-UTR,intron-Distal,intron-Proximal3.498693.99381K562BUD13
chr1166303396630397+3'-UTR,CDS,intron-Distal,intron-Proximal3.374087.08969K562ZNF622
chr1166300786630148+3'-UTR,CDS,intron-Distal,intron-Proximal3.902619.47365K562EFTUD2
chr1166319176631995+3'-UTR4.408634.09791K562IGF2BP2
chr1166301026630154+3'-UTR,CDS,intron-Distal,intron-Proximal4.688436.02529K562U2AF2
chr1166296806629719+3'-UTR,CDS3.499723.32039HepG2PPIG
chr1166249786625054+5'-UTR,intron-Proximal6.064707.49422HepG2DDX3X
chr1166254936625619+5'-UTR,CDS,intron-Proximal3.294825.75678K562SRSF1
chr1166254526625506+5'-UTR,CDS,intron-Proximal4.145156.82597K562DDX3X
chr1166250516625101+5'-UTR,intron-Proximal5.234826.75320K562AQR
chr1166250126625092+5'-UTR,intron-Proximal4.109407.87148HepG2PRPF8
chr1166254876625578+5'-UTR,CDS3.250024.84415HepG2DDX3X
chr1166250996625210+5'-UTR,intron-Distal,intron-Proximal3.842903.11802K562HNRNPK
chr1166254416625487+5'-UTR,intron-Proximal3.812793.76880HepG2DDX3X
chr1166255106625561+5'-UTR,CDS3.883116.28172K562RBM15
chr1166304556630510+intron-Distal,intron-Proximal3.674114.36528HepG2U2AF2
chr1166313216631366+intron-Distal,intron-Proximal5.135774.83371K562EFTUD2
chr1166295576629621+intron-Proximal5.6700110.07464K562SF3B4
chr1166255976625641+intron-Proximal3.784595.83621K562AQR
chr1166255906625597+intron-Proximal3.087103.59391K562AQR
chr1166297196629765+intron-Proximal4.300456.99120K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ILK is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ILK is not available on ENCORE database.

  • 80 RBPs can affect the levels of ILK.  








The Knockdown/knockout RNA-Seq assay for ILK is not available on ENCORE database.





80 RBPs can affect the gene expression of ILK :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ILKENSG00000166333.92215.744201474.223700.5877015.3957014.20710HepG2ACO1
ILKENSG00000166333.92771.152801865.929400.570505.210604.50960HepG2AKAP1
ILKENSG00000166333.91825.549101481.056900.301603.849002.95760HepG2AKAP8L
ILKENSG00000166333.92779.270801760.346800.6587018.7522017.26240HepG2AUH
ILKENSG00000166333.91413.827501186.472000.252801.981601.31980HepG2CALR
ILKENSG00000166333.92106.335901301.353000.694603.772902.87360HepG2CNOT7
ILKENSG00000166333.93016.258801836.657400.7156020.9041019.47180HepG2CELF1
ILKENSG00000166333.92228.506801974.540000.174502.488901.78010HepG2DAZAP1
ILKENSG00000166333.91139.777001363.39420-0.258503.119402.23780HepG2DDX19B
ILKENSG00000166333.91635.499101271.571700.363004.331902.90480HepG2DDX1
ILKENSG00000166333.91645.075601147.706600.519303.466402.61320HepG2DDX55
ILKENSG00000166333.91941.161101476.001000.395103.045202.42400HepG2EIF2S1
ILKENSG00000166333.9868.590601099.26780-0.339802.800901.71300HepG2EIF3G
ILKENSG00000166333.92284.892401948.278600.229802.879002.02820HepG2EIF4G1
ILKENSG00000166333.91112.660401572.35790-0.498902.608001.54560HepG2ESF1
ILKENSG00000166333.9650.587101081.21910-0.732802.889801.85010HepG2FTO
ILKENSG00000166333.91930.487901223.448500.657906.855505.87580HepG2GPKOW
ILKENSG00000166333.91871.791801546.139200.275601.919601.33190HepG2HNRNPK
ILKENSG00000166333.91724.563101167.564300.562605.760304.88540HepG2HNRNPLL
ILKENSG00000166333.92266.584601551.830800.546405.762804.82310HepG2IGF2BP2
ILKENSG00000166333.91869.176301420.773700.395608.235007.03630HepG2ILF2
ILKENSG00000166333.91517.873901957.96680-0.367304.109503.17990HepG2NOL12
ILKENSG00000166333.91768.506801189.627600.571903.097202.15530HepG2PABPC1
ILKENSG00000166333.91201.449701684.07730-0.487208.703307.72530HepG2PCBP1
ILKENSG00000166333.9722.313901268.89450-0.8129017.9930016.30600HepG2PRPF4
ILKENSG00000166333.9511.15230885.00390-0.791908.612007.27190HepG2PRPF8
ILKENSG00000166333.92024.786901182.100000.776305.225804.27300HepG2RAVER1
ILKENSG00000166333.91510.588201907.08900-0.336304.577203.91350HepG2NELFE
ILKENSG00000166333.91152.876301776.21430-0.6236013.4198012.21790HepG2RECQL
ILKENSG00000166333.91608.301801921.96080-0.257001.916101.33580HepG2RPLP0
ILKENSG00000166333.9904.178601307.34050-0.532003.514802.61150HepG2RPS3A
ILKENSG00000166333.91210.46380898.709900.429503.376302.33460HepG2SERBP1
ILKENSG00000166333.92284.666601499.439900.607504.963704.04400HepG2SF3A3
ILKENSG00000166333.9767.526701155.62690-0.590405.995804.99050HepG2SF3B1
ILKENSG00000166333.91323.127001784.08090-0.431206.888406.02140HepG2SF3B4
ILKENSG00000166333.91639.547301444.555300.182602.065401.49730HepG2SMN1
ILKENSG00000166333.91517.084701907.96270-0.330704.844004.23380HepG2SRFBP1
ILKENSG00000166333.91118.431901515.01050-0.437907.218406.40190HepG2SRSF9
ILKENSG00000166333.91852.156301142.420100.697006.415705.44980HepG2SUPV3L1
ILKENSG00000166333.91171.278001673.84850-0.515108.062907.18600HepG2TAF15
ILKENSG00000166333.91126.286801351.66510-0.263202.152401.70040HepG2TIAL1
ILKENSG00000166333.92393.759001933.154400.308202.210501.46700HepG2UBE2L3
ILKENSG00000166333.91571.592701329.775200.240902.695902.00500HepG2UPF1
ILKENSG00000166333.91720.634401252.228800.458309.150508.04820HepG2ZC3H8
ILKENSG00000166333.92434.633701462.496400.7352028.0874026.80900HepG2ZNF622
ILKENSG00000166333.9796.672801181.30060-0.568303.892102.33010HepG2ZRANB2
ILKENSG00000166333.92982.785702087.756600.5146012.2058011.10750K562AGGF1
ILKENSG00000166333.93001.621502294.066600.387704.058302.81780K562AKAP8
ILKENSG00000166333.92761.981502172.390100.346303.281902.56820K562AKAP8L
ILKENSG00000166333.92464.826401746.560700.496905.402204.62930K562AQR
ILKENSG00000166333.91654.39680871.235200.9251014.0939012.07720K562BOP1
ILKENSG00000166333.91593.74250926.353700.7827013.6316011.87110K562CPSF6
ILKENSG00000166333.91753.309901433.825400.290102.978801.72290K562DDX21
ILKENSG00000166333.91244.90990976.300700.350503.122602.01030K562DDX3X
ILKENSG00000166333.91215.52890923.872200.395702.874201.94400K562EFTUD2
ILKENSG00000166333.91893.593701357.388200.480207.958106.83340K562EIF2S2
ILKENSG00000166333.91584.791401063.969200.574706.808305.42990K562FIP1L1
ILKENSG00000166333.91396.25170942.580200.566806.015604.74310K562FMR1
ILKENSG00000166333.91086.90810798.938000.444003.345902.33350K562FTO
ILKENSG00000166333.9535.47800880.07430-0.716805.182904.14630K562G3BP2
ILKENSG00000166333.91749.85740884.424400.9843015.8102013.87100K562GPKOW
ILKENSG00000166333.92324.979001808.860500.362003.713002.84110K562GRSF1
ILKENSG00000166333.91145.01540875.202300.387602.551901.66060K562HNRNPM
ILKENSG00000166333.92417.486001442.414900.7449011.514109.92040K562HSPD1
ILKENSG00000166333.91342.779301030.616600.381602.365401.43770K562IGF2BP2
ILKENSG00000166333.92703.716902305.502500.229802.031501.33350K562KIF1C
ILKENSG00000166333.92762.445102206.889700.323802.997901.86820K562MAK16
ILKENSG00000166333.91200.29020863.303400.475304.608603.45770K562METAP2
ILKENSG00000166333.91489.929701254.320100.248202.731501.92750K562MTPAP
ILKENSG00000166333.91310.133801018.518900.363103.566802.15390K562NCBP2
ILKENSG00000166333.91883.307501393.592700.434409.892408.59830K562NSUN2
ILKENSG00000166333.92369.164001462.390100.695903.500902.34980K562PABPN1
ILKENSG00000166333.9738.552101058.54030-0.519305.857303.81680K562PCBP1
ILKENSG00000166333.91753.435801207.919900.537606.036704.74510K562PPIG
ILKENSG00000166333.93510.544102154.524700.704207.581906.72870K562PUS1
ILKENSG00000166333.92542.455302099.168700.276303.039702.42340K562RBM15
ILKENSG00000166333.91914.177201375.223800.477008.096806.76100K562SF3A3
ILKENSG00000166333.9707.814401031.30120-0.543005.982004.95160K562SRSF1
ILKENSG00000166333.91359.929501043.637200.381802.488501.81510K562TARDBP
ILKENSG00000166333.91224.71600893.501100.454802.595501.69200K562TIAL1
ILKENSG00000166333.91222.57940949.421500.364702.876601.90870K562TRIM56
ILKENSG00000166333.92153.343901743.214400.304704.124502.57250K562TROVE2
ILKENSG00000166333.9594.86010880.53300-0.565803.690302.75890K562U2AF2
ILKENSG00000166333.91299.18170921.183400.495904.254602.96490K562UCHL5
ILKENSG00000166333.92191.655901477.661400.5686012.5650011.17100K562UPF1
ILKENSG00000166333.91129.072001490.85880-0.401004.070402.01440K562UPF2
ILKENSG00000166333.91667.333101264.379200.399004.234603.14330K562WDR3
ILKENSG00000166333.92516.780002069.510800.282202.567401.32910K562WRN
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ILK is not available on ENCORE database.





27 RBPs can affect the splicing of ILK :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEILKENSG00000166333.9chr11+663030166303876630114663019866305296630639-0.060000.004860.07248excludedK562SF3B4
SEILKENSG00000166333.9chr11+662927566294416625409662559066296236629719-0.171000.000000.00000excludedHepG2U2AF1
SEILKENSG00000166333.9chr11+663030166303876630114663019866305296630639-0.092000.001840.03405excludedHepG2U2AF1
SEILKENSG00000166333.9chr11+662992366300206629623662971966301146630198-0.081000.000160.04405excludedK562PCBP1
SEILKENSG00000166333.9chr11+662992366300206629623662971966301146630198-0.059000.001410.01628excludedK562AQR
SEILKENSG00000166333.9chr11+663034566303876629923663019866305296630624-0.129000.001730.01937excludedK562AQR
SEILKENSG00000166333.9chr11+662924766294416625409662559066296236629719-0.217000.001400.09401excludedK562SUPV3L1
SEILKENSG00000166333.9chr11+6626082662617366254096625590662927566294410.175000.000000.00005includedK562HNRNPM
SEILKENSG00000166333.9chr11+662927566294416625409662559066296236629719-0.064000.002690.09978excludedHepG2PCBP1
SEILKENSG00000166333.9chr11+663030166303876630114663019866305296630639-0.068000.007160.09545excludedK562U2AF2
SEILKENSG00000166333.9chr11+6629275662944166254096625590662962366297190.142000.002770.09597includedK562HNRNPK
SEILKENSG00000166333.9chr11+662992366300206629623662971966301146630198-0.077000.000150.00391excludedK562HNRNPC
SEILKENSG00000166333.9chr11+662927566294416625409662559066296236629719-0.321000.000000.00000excludedK562HNRNPC
SEILKENSG00000166333.9chr11+663030166303876630114663019866305296630639-0.084000.001010.01938excludedK562HNRNPC
A3SSILKENSG00000166333.9chr11+6625409662560366254556625603662496066250520.169000.001240.08310longerHepG2SF3A3
A3SSILKENSG00000166333.9chr11+662540966255906625455662559066249606625052-0.252000.000090.02932shorterHepG2HNRNPU
A3SSILKENSG00000166333.9chr11+6629247662944166292756629441662534466255900.059000.000670.00488longerK562AQR
A3SSILKENSG00000166333.9chr11+662992366301986630114663019866296236629719-0.100000.015240.07578shorterK562AQR
A3SSILKENSG00000166333.9chr11+662992366301986630114663019866296236629719-0.171000.000080.01376shorterK562HNRNPC
RIILKENSG00000166333.9chr11+662992366303876629923663019866303016630387-0.072000.000010.00183excludedK562APOBEC3C
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.160000.000580.01156includedK562SF3B4
RIILKENSG00000166333.9chr11+6629923663019866299236630020663011466301980.088000.000000.00000includedK562PUS1
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.361000.000000.00000includedK562PUS1
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.238000.003070.07984includedK562SF3B1
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.103000.000090.00109includedHepG2U2AF2
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.126000.000000.00009includedHepG2PRPF4
RIILKENSG00000166333.9chr11+6629923663019866299236630020663011466301980.121000.000000.00003includedK562PCBP1
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.134000.000040.00966includedK562PCBP1
RIILKENSG00000166333.9chr11+6629923663019866299236630020663011466301980.052000.000800.01222includedHepG2PRPF8
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.054000.000410.00706includedHepG2PRPF8
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.212000.000000.00000includedK562AGGF1
RIILKENSG00000166333.9chr11+6625045662559066250456625107662540966255900.486000.002020.03922includedHepG2IGF2BP3
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.074000.000000.00000includedHepG2PCBP1
RIILKENSG00000166333.9chr11+6629923663019866299236630020663011466301980.053000.001510.03317includedK562RBM22
RIILKENSG00000166333.9chr11+6629923663019866299236630020663011466301980.068000.000000.00000includedK562AKAP8L
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.232000.000000.00000includedK562AKAP8L
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.131000.000020.00032includedHepG2U2AF1
RIILKENSG00000166333.9chr11+6629923663019866299236630020663011466301980.089000.000000.00000includedK562RBM15
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.293000.000000.00000includedK562RBM15
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.185000.000010.00035includedK562U2AF1
RIILKENSG00000166333.9chr11+662992366303876629923663019866303016630387-0.062000.001290.09305excludedK562XRCC6
RIILKENSG00000166333.9chr11+6629923663019866299236630020663011466301980.088000.000040.00107includedK562U2AF2
RIILKENSG00000166333.9chr11+6625045662559066250456625107662540966255900.307000.009270.08087includedHepG2NCBP2
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.058000.000000.00000includedHepG2NCBP2
RIILKENSG00000166333.9chr11+6625045662559066250456625107662540966255900.478000.003070.02370includedHepG2SF3B4
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.085000.000000.00000includedHepG2SF3B4
RIILKENSG00000166333.9chr11+6629923663019866299236630020663011466301980.059000.000000.00000includedK562UTP18
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.271000.000010.00019includedK562UTP18
RIILKENSG00000166333.9chr11+662992366303876629923663019866303016630387-0.051000.001240.08487excludedK562PUM1
RIILKENSG00000166333.9chr11+6629923663019866299236630020663011466301980.134000.000000.00000includedK562AQR
RIILKENSG00000166333.9chr11+6629923663038766299236630198663030166303870.152000.000000.00000includedK562AQR
RIILKENSG00000166333.9chr11+662992366303876629923663019866303016630387-0.082000.000000.00017excludedK562PTBP1
RIILKENSG00000166333.9chr11+662992366303876629923663019866303016630387-0.110000.000030.00090excludedK562FXR1
MXEILKENSG00000166333.9chr11+662962366297196629923663002066254556625590663011466301980.091000.000340.003551includedK562AQR
MXEILKENSG00000166333.9chr11+662608266261736629275662944166254096625590662962366297190.073000.000630.013931includedK562HNRNPC
MXEILKENSG00000166333.9chr11+662608266261736629247662944166254096625590662962366297190.128000.000220.006001includedK562HNRNPC
MXEILKENSG00000166333.9chr11+662608266261736629275662944166254096625590662962366297190.101000.000000.000911includedK562HNRNPM

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ILK is not avaliable on ENCORE database.