CHUK

General Information

Gene Name       : CHUK
Gene ID             : ENSG00000213341.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: CHUK)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CHUKENSG00000213341.1026.9221.3624.14ENCSR000AEF
HepG2CHUKENSG00000213341.1010.1917.3113.75ENCSR985KAT
K562CHUKENSG00000213341.1020.9220.7720.84ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CHUK is not avaliable on ENCORE database.



Proteins bound to RNA
  • CHUK RNA is bound by 6 proteins.  







eCLIP assay for CHUK is not avaliable on ENCORE database.





6 proteins are bound to CHUK RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr10101948662101948744-3'-UTR,intron-Distal5.470039.07598K562PUM2
chr10101948617101948669-3'-UTR,intron-Distal4.044283.71397K562KHSRP
chr10101949314101949383-3'-UTR,CDS,intron-Distal3.918093.49011K562KHSRP
chr10101989242101989321-5'-UTR,CDS,intron-Distal4.910998.90399HepG2DDX3X
chr10101978469101978537-CDS,intron-Distal,intron-Proximal4.215073.45943HepG2BCLAF1
chr10101977734101977875-CDS,intron-Distal,intron-Proximal4.124076.22576HepG2BCLAF1
chr10101988699101988814-intron-Distal5.449698.04355K562EIF4G2
chr10101989003101989077-intron-Distal4.271093.64144K562EFTUD2
chr10101989091101989148-intron-Distal5.004253.65355K562EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CHUK is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CHUK is not available on ENCORE database.

  • 87 RBPs can affect the levels of CHUK.  








The Knockdown/knockout RNA-Seq assay for CHUK is not available on ENCORE database.





87 RBPs can affect the gene expression of CHUK :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CHUKENSG00000213341.6766.71920570.393400.426604.730603.97540HepG2ACO1
CHUKENSG00000213341.6363.35240496.47530-0.450402.669301.68810HepG2ADAR
CHUKENSG00000213341.61465.54760713.526601.0383012.9438011.88070HepG2AKAP1
CHUKENSG00000213341.6688.62260966.15070-0.488506.645905.65340HepG2AUH
CHUKENSG00000213341.6437.82720594.34060-0.440902.202701.40010HepG2BCLAF1
CHUKENSG00000213341.6708.66600512.245500.468203.830302.94450HepG2CALR
CHUKENSG00000213341.6428.83130677.55800-0.659904.309903.07900HepG2CCAR1
CHUKENSG00000213341.6300.21720658.80960-1.1339013.6067012.21760HepG2CPSF6
CHUKENSG00000213341.6369.13820509.85560-0.465902.377501.30810HepG2DDX1
CHUKENSG00000213341.6978.17630683.557700.516903.955803.21940HepG2DDX3X
CHUKENSG00000213341.6357.95600482.19200-0.429802.633501.67500HepG2DHX30
CHUKENSG00000213341.6394.70670499.95720-0.341002.230401.59320HepG2DNAJC21
CHUKENSG00000213341.6393.15720495.47250-0.333702.540801.91080HepG2DNAJC2
CHUKENSG00000213341.6250.26670564.48410-1.1735011.4535010.29730HepG2EIF2S1
CHUKENSG00000213341.6491.37210307.486100.676204.884103.70860HepG2EIF3D
CHUKENSG00000213341.6432.17580607.32130-0.490802.318201.68580HepG2EIF4B
CHUKENSG00000213341.6734.93060556.308400.401602.376301.65870HepG2FIP1L1
CHUKENSG00000213341.6498.88110746.82770-0.582104.089003.32310HepG2GPKOW
CHUKENSG00000213341.6311.26800504.74620-0.697405.490404.62330HepG2HNRNPA1
CHUKENSG00000213341.6513.71700698.34670-0.443004.558503.66440HepG2HNRNPF
CHUKENSG00000213341.6506.01580746.40680-0.560807.609506.54100HepG2HNRNPL
CHUKENSG00000213341.6433.06570712.71000-0.718706.326205.41850HepG2HNRNPLL
CHUKENSG00000213341.6390.22680557.70350-0.515205.032304.23460HepG2HNRNPU
CHUKENSG00000213341.6498.19320687.66830-0.465004.092103.22590HepG2IGF2BP1
CHUKENSG00000213341.6784.59750593.507700.402602.559001.90760HepG2IGF2BP2
CHUKENSG00000213341.6384.38300569.67970-0.567606.757005.66200HepG2ILF2
CHUKENSG00000213341.6658.03030487.846900.431602.914001.74960HepG2LARP7
CHUKENSG00000213341.61015.66800629.507200.690006.532805.53570HepG2MAGOH
CHUKENSG00000213341.6932.88600633.060000.559304.056503.30640HepG2MATR3
CHUKENSG00000213341.6636.05580450.474900.497604.278603.28470HepG2MSI2
CHUKENSG00000213341.6414.77440726.83740-0.809305.109003.76540HepG2MTPAP
CHUKENSG00000213341.6183.41260378.20920-1.044106.430104.60370HepG2NAA15
CHUKENSG00000213341.6834.69370647.996200.365202.105401.54970HepG2NCBP2
CHUKENSG00000213341.6596.11660812.48690-0.446804.396303.43630HepG2NOL12
CHUKENSG00000213341.6451.78440631.94240-0.484203.159302.36100HepG2NSUN2
CHUKENSG00000213341.6300.16740497.43110-0.728707.716806.53500HepG2PPIL4
CHUKENSG00000213341.61029.20820823.283900.322003.689203.02530HepG2PUM1
CHUKENSG00000213341.6676.50730822.69520-0.282301.995701.42000HepG2PUM2
CHUKENSG00000213341.61182.03590522.479801.177709.779008.50780HepG2RAVER1
CHUKENSG00000213341.61261.29900927.148400.443905.525704.85680HepG2RBM22
CHUKENSG00000213341.6917.85440638.311500.523906.149405.39690HepG2NELFE
CHUKENSG00000213341.6740.52360594.465300.316902.402801.82310HepG2RECQL
CHUKENSG00000213341.6750.66660513.239900.548403.795002.89260HepG2RRP9
CHUKENSG00000213341.6349.63990496.67340-0.506404.604403.80800HepG2SAFB2
CHUKENSG00000213341.61229.41920560.592401.1329012.5944011.09540HepG2SF3A3
CHUKENSG00000213341.6514.23930743.61100-0.532106.880905.85530HepG2SLBP
CHUKENSG00000213341.61398.371101047.177800.417106.286305.61480HepG2SRFBP1
CHUKENSG00000213341.61269.87070623.297401.0266025.6323024.51170HepG2SRSF1
CHUKENSG00000213341.6461.84710686.11620-0.571006.970005.94580HepG2SRSF7
CHUKENSG00000213341.6647.99970507.070900.353702.965302.39790HepG2SRSF9
CHUKENSG00000213341.6761.85510560.196600.443503.953003.30180HepG2TAF15
CHUKENSG00000213341.6500.43860694.63020-0.473103.258302.47800HepG2TARDBP
CHUKENSG00000213341.6412.38480542.00030-0.394302.789702.28740HepG2TIAL1
CHUKENSG00000213341.6307.27170546.75190-0.8314011.1905010.16900HepG2TRIM56
CHUKENSG00000213341.6667.78650476.019700.488303.576902.86660HepG2U2AF1
CHUKENSG00000213341.6418.16440613.07370-0.552002.547701.58740HepG2UPF2
CHUKENSG00000213341.6358.74530479.98770-0.420003.041002.41820HepG2UTP3
CHUKENSG00000213341.6356.97100659.00220-0.884507.850406.64130HepG2XRN2
CHUKENSG00000213341.6517.75680414.916300.319402.313201.69190HepG2ZC3H8
CHUKENSG00000213341.6968.61530546.780300.8249018.5598017.45510HepG2ZNF622
CHUKENSG00000213341.6634.78610464.324000.451002.447801.34340K562AARS
CHUKENSG00000213341.61930.021801351.415700.514005.085304.33200K562AQR
CHUKENSG00000213341.6617.86440832.96980-0.431004.177102.50430K562BCCIP
CHUKENSG00000213341.6173.48190263.97390-0.605602.974101.87530K562CCAR1
CHUKENSG00000213341.6747.62670932.05200-0.318102.547601.48650K562CPEB4
CHUKENSG00000213341.6412.37160633.22310-0.618805.855604.72050K562CPSF6
CHUKENSG00000213341.61240.45200964.448100.363004.538403.73100K562DDX47
CHUKENSG00000213341.6906.30250651.535300.476005.041403.80700K562DKC1
CHUKENSG00000213341.6415.51460584.56350-0.492504.782203.17090K562EIF2S1
CHUKENSG00000213341.6698.365501005.81810-0.526306.778405.72660K562EIF2S2
CHUKENSG00000213341.6801.56890598.368100.421703.775202.85570K562EIF3G
CHUKENSG00000213341.6308.23120500.71910-0.700007.332505.31470K562EIF4B
CHUKENSG00000213341.6633.31960835.57150-0.399802.906002.03600K562FIP1L1
CHUKENSG00000213341.6315.60710644.28950-1.0296011.9200010.06410K562FMR1
CHUKENSG00000213341.6977.95240578.241100.7580012.3822011.19430K562FXR1
CHUKENSG00000213341.6821.25700576.926400.509303.075702.32380K562G3BP2
CHUKENSG00000213341.6991.713801340.43590-0.434703.942703.04350K562GRSF1
CHUKENSG00000213341.6569.91980824.66730-0.533105.352503.87480K562HNRNPA1
CHUKENSG00000213341.6268.70570453.75100-0.755906.102804.32290K562HNRNPF
CHUKENSG00000213341.61054.77170698.654900.594205.419103.63540K562HNRNPK
CHUKENSG00000213341.6340.72990515.30080-0.596804.262802.36350K562LIN28B
CHUKENSG00000213341.6461.71110590.13000-0.354002.089501.32800K562METAP2
CHUKENSG00000213341.6643.86580800.80800-0.314703.190502.39340K562NSUN2
CHUKENSG00000213341.6337.51390500.27090-0.567803.197101.62790K562NUSAP1
CHUKENSG00000213341.6875.63750654.104300.420703.168502.12140K562PCBP2
CHUKENSG00000213341.6634.71980948.53710-0.579605.549004.32100K562PPIG
CHUKENSG00000213341.6922.81460662.213200.478602.060201.40900K562PRPF8
CHUKENSG00000213341.6225.22560455.61690-1.016509.530507.64120K562PSIP1
CHUKENSG00000213341.61277.42870600.489001.0889016.5060015.21790K562PUS1
CHUKENSG00000213341.6252.57210383.57210-0.602803.493702.29130K562SRSF4
CHUKENSG00000213341.6732.57430484.243700.597106.302905.05760K562SYNCRIP
CHUKENSG00000213341.6509.74440683.52720-0.423203.295202.39050K562TIA1
CHUKENSG00000213341.6317.94060438.23510-0.462902.342101.48580K562TIAL1
CHUKENSG00000213341.6304.26320465.49620-0.613404.247003.01870K562TRIM56
CHUKENSG00000213341.6685.84950849.11280-0.308102.931002.19180K562UPF1
CHUKENSG00000213341.6580.07680726.56050-0.324802.188801.41090K562WDR3
CHUKENSG00000213341.6788.44180492.446100.678903.219601.48720K562XRCC6
CHUKENSG00000213341.61053.242901522.58500-0.531704.902003.70160K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CHUK is not available on ENCORE database.





7 RBPs can affect the splicing of CHUK :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECHUKENSG00000213341.6chr10-1019522151019524501019506251019507251019530541019531800.264000.000030.00169includedK562AKAP8L
SECHUKENSG00000213341.6chr10-101961844101961906101960427101960537101964262101964414-0.231000.000350.01356excludedK562AKAP8L
SECHUKENSG00000213341.6chr10-1019522151019524501019506251019507251019530541019531880.214000.000000.00000includedK562AQR
SECHUKENSG00000213341.6chr10-101961844101961906101960427101960537101964262101964414-0.216000.000000.00000excludedK562AQR
SECHUKENSG00000213341.6chr10-101954181101954278101953740101953888101959727101959777-0.064000.008270.06982excludedK562AQR
SECHUKENSG00000213341.6chr10-101978764101978889101978474101978582101979026101979116-0.057000.001550.01766excludedK562AQR
SECHUKENSG00000213341.6chr10-1019522151019524501019506251019507251019530541019531800.129000.004240.05490includedK562PUS1
SECHUKENSG00000213341.6chr10-101961844101961906101960427101960537101964262101964414-0.178000.000780.02834excludedK562UTP18
SECHUKENSG00000213341.6chr10-101961844101961906101960427101960537101964262101964414-0.211000.005440.07752excludedK562U2AF2
SECHUKENSG00000213341.6chr10-1019522151019524501019506251019507251019530541019531800.219000.000080.00354includedK562RBM15
SECHUKENSG00000213341.6chr10-1019522151019524501019506251019507251019530541019531800.144000.002890.06211includedK562AGGF1
A3SSCHUKENSG00000213341.6chr10-1019784741019786371019784741019785821019787641019789540.103000.000050.00049longerK562AQR
A3SSCHUKENSG00000213341.6chr10-1019597271019597981019597271019597771019604271019606440.217000.000000.00000longerK562AQR
A3SSCHUKENSG00000213341.6chr10-1019604271019606061019604271019605371019618441019619060.051000.000360.00280longerK562AQR
A3SSCHUKENSG00000213341.6chr10-1019506251019508241019506251019507251019530541019531880.282000.000000.00000longerK562AQR
A3SSCHUKENSG00000213341.6chr10-1019787641019789511019787641019788891019790261019792710.205000.000000.00000longerK562AQR
A3SSCHUKENSG00000213341.6chr10-1019826221019828691019826221019827371019856791019858470.082000.000010.00013longerK562AQR
MXECHUKENSG00000213341.6chr10-1019506251019507251019522151019524501019481231019493841019530541019531880.068000.001660.014161includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CHUK is not avaliable on ENCORE database.