AKR1C3

General Information

Gene Name       : AKR1C3
Gene ID             : ENSG00000196139.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: AKR1C3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878AKR1C3ENSG00000196139.130.000.000.00ENCSR000AEF
HepG2AKR1C3ENSG00000196139.13214.65240.86227.75ENCSR985KAT
K562AKR1C3ENSG00000196139.136.127.046.58ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for AKR1C3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • AKR1C3 RNA is bound by 10 proteins.  







eCLIP assay for AKR1C3 is not avaliable on ENCORE database.





10 proteins are bound to AKR1C3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1051396945139712+3'-UTR,CDS,intron-Distal3.706114.72530HepG2G3BP1
chr1051497875149851+3'-UTR4.616494.46521HepG2TIA1
chr1051386015138610+3'-UTR,CDS,intron-Proximal3.204193.50786HepG2G3BP1
chr1051397275139792+3'-UTR,CDS,intron-Distal,intron-Proximal4.826245.32906HepG2AQR
chr1051496835149774+3'-UTR,CDS3.0254520.75370HepG2LARP4
chr1051397125139742+3'-UTR,CDS,intron-Distal3.281396.11586HepG2G3BP1
chr1051386105138681+3'-UTR,CDS5.4063810.59349HepG2G3BP1
chr1051497795149847+3'-UTR3.5130212.04831HepG2LARP4
chr1051397315139796+CDS,intron-Distal,intron-Proximal5.100035.01842HepG2PRPF8
chr1051442655144327+CDS,intron-Proximal3.127564.68369HepG2U2AF2
chr1051443535144403+CDS,intron-Proximal3.178276.98493HepG2G3BP1
chr1051478555147868+CDS4.376633.88780HepG2G3BP1
chr1051409505141035+CDS,intron-Distal,intron-Proximal3.018916.09708HepG2BUD13
chr1051496515149686+CDS,intron-Proximal4.737176.58399HepG2G3BP1
chr1051442925144339+CDS,intron-Proximal3.613907.11962HepG2G3BP1
chr1051414595141557+CDS,intron-Proximal3.327585.57238HepG2AQR
chr1051415345141619+CDS4.6896120.17286HepG2G3BP1
chr1051415175141527+CDS,intron-Proximal4.2774811.09241HepG2G3BP1
chr1051477865147845+CDS,intron-Proximal3.9771210.54900HepG2G3BP1
chr1051446765144701+CDS,intron-Proximal4.413635.12780HepG2G3BP1
chr1051416325141693+CDS,intron-Proximal3.396977.35853HepG2PRPF8
chr1051415165141609+CDS,intron-Proximal3.934315.87392HepG2ZNF800
chr1051410375141072+CDS,intron-Distal,intron-Proximal3.085427.77345HepG2G3BP1
chr1051404615140549+intron-Distal3.264206.74510HepG2HNRNPC
chr1051474435147480+intron-Distal4.598113.79000HepG2U2AF2
chr1051483735148450+intron-Distal5.214576.84553HepG2U2AF2
chr1051474405147488+intron-Distal3.958523.47043HepG2KHSRP
chr1051475355147597+intron-Distal5.517478.57494HepG2U2AF2
chr1051471145147162+intron-Distal3.791624.50744HepG2U2AF2
chr1051444335144533+intron-Distal,intron-Proximal4.1810210.82383HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for AKR1C3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for AKR1C3 is not available on ENCORE database.

  • 113 RBPs can affect the levels of AKR1C3.  








The Knockdown/knockout RNA-Seq assay for AKR1C3 is not available on ENCORE database.





113 RBPs can affect the gene expression of AKR1C3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
AKR1C3ENSG00000196139.73812.174903043.092700.325002.234701.38510HepG2ABCF1
AKR1C3ENSG00000196139.71327.104002980.66890-1.1674054.9307053.07790HepG2ACO1
AKR1C3ENSG00000196139.72865.287902143.812900.418404.007202.83350HepG2ADAR
AKR1C3ENSG00000196139.72873.873407361.31780-1.3570028.2411026.75410HepG2AKAP1
AKR1C3ENSG00000196139.74144.114802994.389200.4687011.237909.82570HepG2AKAP8L
AKR1C3ENSG00000196139.74261.008306090.98310-0.515505.757704.64620HepG2ASCC1
AKR1C3ENSG00000196139.71788.167902245.12010-0.328302.226201.38950HepG2BCCIP
AKR1C3ENSG00000196139.73086.055401328.766001.2156030.7161029.08960HepG2BOP1
AKR1C3ENSG00000196139.71989.956202722.52960-0.452203.133002.09040HepG2CCAR1
AKR1C3ENSG00000196139.74462.239905786.81750-0.375003.412002.55900HepG2CIRBP
AKR1C3ENSG00000196139.74616.882502979.679900.6317027.0051025.41410HepG2CKAP4
AKR1C3ENSG00000196139.72041.874301219.823400.7431010.423009.17180HepG2CPSF6
AKR1C3ENSG00000196139.72661.428203507.07920-0.398106.837105.91350HepG2CELF1
AKR1C3ENSG00000196139.71122.223102787.24130-1.3125036.4876034.44720HepG2DDX21
AKR1C3ENSG00000196139.7911.402502207.47860-1.2762022.8158020.93190HepG2DDX55
AKR1C3ENSG00000196139.73031.565101385.217601.129909.777508.01890HepG2DDX59
AKR1C3ENSG00000196139.73491.876502565.787600.444504.744003.44080HepG2DDX5
AKR1C3ENSG00000196139.72977.216802082.081500.515806.798005.31570HepG2DHX30
AKR1C3ENSG00000196139.73847.218102851.604200.431909.609508.50330HepG2DKC1
AKR1C3ENSG00000196139.72882.464102158.719700.417007.094606.01060HepG2DNAJC21
AKR1C3ENSG00000196139.71810.012602139.64850-0.241403.574402.85090HepG2DNAJC2
AKR1C3ENSG00000196139.73547.988905823.39490-0.7149010.108509.01640HepG2EIF2S1
AKR1C3ENSG00000196139.72828.877606435.80450-1.1859021.7194019.96930HepG2EIF4A3
AKR1C3ENSG00000196139.76955.295003720.241700.9026044.6696042.18830HepG2EIF4G1
AKR1C3ENSG00000196139.74303.844703563.688100.272202.304701.55740HepG2EIF4G2
AKR1C3ENSG00000196139.74090.848805823.88880-0.5096014.6946013.48590HepG2ETF1
AKR1C3ENSG00000196139.73512.158802912.343200.270102.529501.73070HepG2EWSR1
AKR1C3ENSG00000196139.71365.777703072.64000-1.1698021.1785019.41480HepG2FIP1L1
AKR1C3ENSG00000196139.72441.800901837.324600.410202.932801.62710HepG2FKBP4
AKR1C3ENSG00000196139.73256.563604090.89070-0.329103.395602.52880HepG2FUBP3
AKR1C3ENSG00000196139.71998.388303229.01880-0.692305.930504.34660HepG2FUS
AKR1C3ENSG00000196139.72730.958406492.64410-1.2494029.2640027.31810HepG2FXR1
AKR1C3ENSG00000196139.73563.285606023.30710-0.7573010.321909.07910HepG2G3BP1
AKR1C3ENSG00000196139.71180.702501871.78560-0.664808.412206.89250HepG2GEMIN5
AKR1C3ENSG00000196139.71647.016902517.04840-0.611907.509005.81770HepG2GNB2L1
AKR1C3ENSG00000196139.71869.752201382.611000.435403.263002.57300HepG2GPKOW
AKR1C3ENSG00000196139.71457.988402179.40070-0.580007.862006.85620HepG2HNRNPA1
AKR1C3ENSG00000196139.72709.399003465.44600-0.355105.724604.46110HepG2HNRNPA2B1
AKR1C3ENSG00000196139.74599.422702562.477900.8438032.6718030.66830HepG2HNRNPF
AKR1C3ENSG00000196139.77257.574206098.145800.251002.059801.45150HepG2HNRNPK
AKR1C3ENSG00000196139.74460.920603434.552900.377108.993807.84530HepG2HNRNPL
AKR1C3ENSG00000196139.71933.892601319.465000.551505.449504.59650HepG2HNRNPLL
AKR1C3ENSG00000196139.71276.123002119.56480-0.7320013.5074011.66910HepG2HNRNPM
AKR1C3ENSG00000196139.72983.754102408.150400.309105.248604.43460HepG2HNRNPU
AKR1C3ENSG00000196139.74968.752402523.287600.9775028.5599026.53570HepG2IGF2BP1
AKR1C3ENSG00000196139.72516.445505745.28840-1.191006.953205.43670HepG2IGF2BP3
AKR1C3ENSG00000196139.73246.841906158.11770-0.9235011.792509.63860HepG2KHSRP
AKR1C3ENSG00000196139.73295.397202724.492900.274402.507601.53480HepG2KIF1C
AKR1C3ENSG00000196139.72118.136402875.89870-0.441203.008802.13990HepG2LARP4
AKR1C3ENSG00000196139.72924.196406494.90720-1.1513022.9462021.16540HepG2MAGOH
AKR1C3ENSG00000196139.71831.736806531.39060-1.8342050.6467048.27560HepG2MATR3
AKR1C3ENSG00000196139.71539.590102200.18990-0.515102.957901.86740HepG2METAP2
AKR1C3ENSG00000196139.71169.350402486.11910-1.0882028.2026026.06870HepG2MSI2
AKR1C3ENSG00000196139.74122.193006685.34900-0.697609.267508.14860HepG2NCBP2
AKR1C3ENSG00000196139.73110.962202230.049600.480205.095103.15670HepG2NIP7
AKR1C3ENSG00000196139.72000.924101170.069800.774007.105205.94350HepG2NSUN2
AKR1C3ENSG00000196139.73570.662405954.23310-0.7377010.391109.01420HepG2PABPC4
AKR1C3ENSG00000196139.72079.143202383.66040-0.197202.107001.35990HepG2PARN
AKR1C3ENSG00000196139.75269.963506423.58400-0.285605.471504.66420HepG2PCBP1
AKR1C3ENSG00000196139.71384.363601738.52270-0.328603.415302.04720HepG2PKM
AKR1C3ENSG00000196139.71802.642702147.87830-0.252802.683301.95610HepG2PPIL4
AKR1C3ENSG00000196139.73950.296002709.738600.5437014.3910012.84360HepG2PRPF4
AKR1C3ENSG00000196139.72171.330901702.576400.350802.435901.67600HepG2PRPF8
AKR1C3ENSG00000196139.72688.778506536.14840-1.2815083.3686081.37270HepG2PTBP1
AKR1C3ENSG00000196139.75900.269203569.215600.725106.964406.07440HepG2PUF60
AKR1C3ENSG00000196139.72358.029103789.01700-0.6842021.8154020.47420HepG2PUM1
AKR1C3ENSG00000196139.72480.006003786.16410-0.6104010.072308.83490HepG2PUM2
AKR1C3ENSG00000196139.72459.642603035.95470-0.303705.439304.62830HepG2PUS1
AKR1C3ENSG00000196139.73987.586203207.413700.314003.822502.83370HepG2RBM15
AKR1C3ENSG00000196139.71714.054504867.70860-1.5058085.3181083.22710HepG2RBM22
AKR1C3ENSG00000196139.74578.076006424.57510-0.488907.987806.89340HepG2RBM25
AKR1C3ENSG00000196139.73463.872807274.17920-1.0704062.6561060.89760HepG2NELFE
AKR1C3ENSG00000196139.74557.852606774.77590-0.5718019.8405018.44760HepG2RECQL
AKR1C3ENSG00000196139.76207.291602760.740401.1688031.7409029.99270HepG2RPLP0
AKR1C3ENSG00000196139.74551.245002897.642300.651304.955003.70950HepG2RPS10
AKR1C3ENSG00000196139.71078.495502045.62500-0.9235019.3507017.94490HepG2RPS19
AKR1C3ENSG00000196139.72019.732002742.86340-0.441503.433202.54220HepG2RPS2
AKR1C3ENSG00000196139.72623.011401684.169500.639106.390605.25070HepG2RRP9
AKR1C3ENSG00000196139.72527.807002053.053500.300002.376101.50150HepG2SERBP1
AKR1C3ENSG00000196139.73008.234101305.920901.2037016.7852015.20640HepG2SF3B1
AKR1C3ENSG00000196139.73679.715606805.13290-0.8870044.5908042.76640HepG2SF3B4
AKR1C3ENSG00000196139.71087.930002530.49830-1.217804.165002.32430HepG2SFPQ
AKR1C3ENSG00000196139.73800.602403422.602700.151002.301801.65250HepG2SLBP
AKR1C3ENSG00000196139.71446.356502500.92960-0.7900032.6778030.87690HepG2SMN1
AKR1C3ENSG00000196139.73000.156501453.097901.0458011.053409.50530HepG2SNRNP70
AKR1C3ENSG00000196139.78511.903005497.924600.6305029.0252027.84860HepG2SRFBP1
AKR1C3ENSG00000196139.72852.988202102.403400.440303.537501.70550HepG2SRP68
AKR1C3ENSG00000196139.73612.145707103.02060-0.9756059.8296058.27490HepG2SRSF1
AKR1C3ENSG00000196139.72886.152003524.24470-0.288204.301203.55100HepG2SRSF5
AKR1C3ENSG00000196139.74428.770502517.624700.8147030.7022028.88590HepG2SRSF7
AKR1C3ENSG00000196139.72751.044602051.701700.423102.868801.61320HepG2STAU1
AKR1C3ENSG00000196139.73146.745604324.25210-0.458603.324702.10670HepG2STIP1
AKR1C3ENSG00000196139.71880.904904007.89650-1.0914063.3434061.11490HepG2SUCLG1
AKR1C3ENSG00000196139.73957.682205866.48550-0.5678011.040309.40330HepG2TIA1
AKR1C3ENSG00000196139.72763.402503487.19620-0.335603.560402.55640HepG2TUFM
AKR1C3ENSG00000196139.71701.628401298.020900.390502.875702.10320HepG2UCHL5
AKR1C3ENSG00000196139.72682.645102011.922700.415002.302601.39350HepG2UPF2
AKR1C3ENSG00000196139.73689.992503142.104100.231802.986001.90300HepG2UTP18
AKR1C3ENSG00000196139.72485.380102951.35030-0.247903.618702.94920HepG2UTP3
AKR1C3ENSG00000196139.71886.807803244.01220-0.781807.350505.69070HepG2XRCC6
AKR1C3ENSG00000196139.778.63530161.72350-1.040304.410803.70170K562AQR
AKR1C3ENSG00000196139.7167.9849081.680201.040203.732002.46410K562CNOT7
AKR1C3ENSG00000196139.795.6238044.946001.089103.440702.56340K562CPSF6
AKR1C3ENSG00000196139.7130.8571059.218401.143804.328702.69090K562EEF2
AKR1C3ENSG00000196139.7109.6835057.204800.939002.919801.98330K562EFTUD2
AKR1C3ENSG00000196139.7141.0429078.652900.842503.545802.74670K562EIF2S2
AKR1C3ENSG00000196139.791.85860154.46490-0.749802.822401.87550K562EIF4G2
AKR1C3ENSG00000196139.7151.7492063.492301.256906.584805.23590K562FIP1L1
AKR1C3ENSG00000196139.7134.0272050.884901.397107.054604.79670K562FUS
AKR1C3ENSG00000196139.7139.9704082.155700.768602.961402.33850K562FXR1
AKR1C3ENSG00000196139.7102.8082042.907901.260504.380803.38770K562GPKOW
AKR1C3ENSG00000196139.7113.0425060.637500.898502.925402.31390K562HNRNPC
AKR1C3ENSG00000196139.7135.2617052.227101.372806.269404.78560K562HNRNPM
AKR1C3ENSG00000196139.7131.9819085.185000.631602.254801.44820K562HNRNPU
AKR1C3ENSG00000196139.7136.2148086.076700.662102.099901.40390K562HSPD1
AKR1C3ENSG00000196139.7157.5972074.416701.082403.124801.60170K562ILF2
AKR1C3ENSG00000196139.7118.6653058.648701.016603.866002.17080K562LARP7
AKR1C3ENSG00000196139.787.3950041.884801.061002.935502.03190K562METAP2
AKR1C3ENSG00000196139.7133.1837078.889800.755402.691001.48070K562NCBP2
AKR1C3ENSG00000196139.7132.8336076.855300.789303.144902.35380K562NSUN2
AKR1C3ENSG00000196139.7114.2844055.667301.037603.193002.38680K562PRPF8
AKR1C3ENSG00000196139.7276.52000168.538500.714203.457802.54850K562PUF60
AKR1C3ENSG00000196139.7138.4683049.565701.482007.687606.03140K562RCC2
AKR1C3ENSG00000196139.7154.9820056.688901.450906.744205.45710K562RPS19
AKR1C3ENSG00000196139.7129.9632058.965701.140104.637602.35300K562SLTM
AKR1C3ENSG00000196139.7159.7858076.336601.065604.027201.90130K562SMN1
AKR1C3ENSG00000196139.798.3873052.290300.911802.686501.76600K562TIAL1
AKR1C3ENSG00000196139.7181.2779081.492001.153407.358906.25440K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for AKR1C3 is not available on ENCORE database.





2 RBPs can affect the splicing of AKR1C3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEAKR1C3ENSG00000196139.7chr10+513962551397425138601513876951415185141606-0.139000.000020.00078excludedHepG2U2AF1
SEAKR1C3ENSG00000196139.7chr10+513962551397425138601513876951415185141641-0.194000.000170.00316excludedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for AKR1C3 is not avaliable on ENCORE database.