ZNF274

General Information

Gene Name       : ZNF274
Gene ID             : ENSG00000171606.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ZNF274)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ZNF274ENSG00000171606.177.7710.178.97ENCSR000AEF
HepG2ZNF274ENSG00000171606.1712.8715.6814.27ENCSR985KAT
K562ZNF274ENSG00000171606.1723.6721.4922.58ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
ZNF274Ribo-STAMP-293TshRNABGRSLV05-3,BGRSLV05-4BGRSLV05-1,BGRSLV05-2NotSatisfiedENCORE2
ZNF274Ribo-STAMP-293TshRNABGRSLV08-21,BGRSLV08-22BGRSLV08-1,BGRSLV08-2NotSatisfiedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ZNF274 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ZNF274 RNA is bound by 10 proteins.  







eCLIP assay for ZNF274 is not avaliable on ENCORE database.





10 proteins are bound to ZNF274 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr195869485758694913+5'-UTR,intron-Distal,intron-Proximal4.019636.80869K562AQR
chr195869522258695306+5'-UTR,intron-Distal,intron-Proximal3.677816.26686K562SF3B4
chr195869480458694860+5'-UTR,intron-Proximal3.409046.18341HepG2PRPF8
chr195869524458695305+5'-UTR,intron-Distal,intron-Proximal4.455117.92018K562AQR
chr195869481158694898+5'-UTR,intron-Proximal4.710193.31283K562PRPF8
chr195869480358694852+5'-UTR,intron-Proximal4.600303.59236HepG2AQR
chr195869480858694857+5'-UTR,intron-Proximal6.0121210.48996K562AQR
chr195869524858695316+5'-UTR,intron-Distal,intron-Proximal3.652456.43995K562PRPF8
chr195869706958697240+CDS,intron-Distal,intron-Proximal3.605125.44104K562SRSF1
chr195869702658697083+CDS,intron-Distal,intron-Proximal3.454034.52919HepG2SF3B4
chr195869838658698410+CDS,intron-Distal,intron-Proximal4.496517.46483HepG2PRPF8
chr195869709258697221+CDS,intron-Distal,intron-Proximal3.176096.27819HepG2PPIG
chr195872143258721485+CDS,intron-Proximal5.331155.69951K562AQR
chr195872300958723055+CDS,intron-Proximal3.299454.77136HepG2PPIG
chr195869536358695436+CDS,intron-Distal,intron-Proximal4.182397.79506K562AQR
chr195869839958698478+CDS,intron-Distal,intron-Proximal3.423735.17453K562PRPF8
chr195869706158697216+CDS,intron-Distal,intron-Proximal3.854693.25205K562GRWD1
chr195869535658695422+CDS,intron-Distal,intron-Proximal3.715914.95247K562PRPF8
chr195869835458698428+CDS,intron-Distal,intron-Proximal3.877083.79347HepG2GRWD1
chr195870238658702470+intron-Distal3.123653.46325HepG2SUGP2
chr195869841058698450+intron-Distal,intron-Proximal5.7274411.12141HepG2PRPF8
chr195871929658719343+intron-Distal4.040387.39675K562EIF4G2
chr195871955558719634+intron-Distal4.128637.97776K562TARDBP
chr195871939258719490+intron-Distal5.355318.06678K562TARDBP
chr195871958158719661+intron-Distal3.733216.76965K562EIF4G2
chr195872078358720882+intron-Distal3.874555.89423HepG2HNRNPM
chr195870558158705651+intron-Distal3.728643.08314K562TARDBP
chr195872068458720755+intron-Distal3.204803.39857HepG2HNRNPM
chr195872079358720876+intron-Distal3.763473.28572K562HNRNPM
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ZNF274 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ZNF274 is not available on ENCORE database.

  • 98 RBPs can affect the levels of ZNF274.  








The Knockdown/knockout RNA-Seq assay for ZNF274 is not available on ENCORE database.





98 RBPs can affect the gene expression of ZNF274 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ZNF274ENSG00000171606.13680.75420498.699300.448904.734003.97850HepG2ACO1
ZNF274ENSG00000171606.13527.91830385.705900.452702.775001.77630HepG2ADAR
ZNF274ENSG00000171606.13902.69570500.980200.8494015.7767014.15500HepG2AKAP8L
ZNF274ENSG00000171606.13680.24700475.311800.517103.541102.65480HepG2ASCC1
ZNF274ENSG00000171606.13986.99330772.585300.353203.552102.79150HepG2AUH
ZNF274ENSG00000171606.13443.17810322.010100.460702.385301.55280HepG2BCLAF1
ZNF274ENSG00000171606.13727.61670351.883601.0480013.7077012.51750HepG2BOP1
ZNF274ENSG00000171606.13803.52840498.516200.6886011.4056010.24160HepG2CKAP4
ZNF274ENSG00000171606.13527.75630323.056000.708005.712904.75840HepG2CPSF6
ZNF274ENSG00000171606.131133.88070595.188500.9298019.7647018.36420HepG2CELF1
ZNF274ENSG00000171606.13577.90040461.191100.325402.734201.90470HepG2DDX19B
ZNF274ENSG00000171606.13505.91260364.317200.473602.568601.81950HepG2DDX55
ZNF274ENSG00000171606.13559.76260366.851300.609502.689601.72740HepG2DDX59
ZNF274ENSG00000171606.13640.98600438.251600.548404.162202.92740HepG2DDX5
ZNF274ENSG00000171606.13633.68920472.655000.422902.264701.70040HepG2DDX6
ZNF274ENSG00000171606.13525.25430374.593000.487603.366902.28930HepG2DHX30
ZNF274ENSG00000171606.13502.26660353.900800.505002.641001.56340HepG2AGO1
ZNF274ENSG00000171606.13624.42370454.433500.458402.751102.15960HepG2EIF2S1
ZNF274ENSG00000171606.13586.38360434.248300.433202.976801.75820HepG2EIF2S2
ZNF274ENSG00000171606.13871.43210502.230800.794907.270206.23540HepG2EIF4A3
ZNF274ENSG00000171606.131037.84490488.937901.0858010.694909.38420HepG2EIF4B
ZNF274ENSG00000171606.131289.80020887.025400.540008.928207.95170HepG2ETF1
ZNF274ENSG00000171606.13769.34140577.992400.412502.251401.55330HepG2FIP1L1
ZNF274ENSG00000171606.13531.00510358.646300.566104.152003.19700HepG2FUBP3
ZNF274ENSG00000171606.13649.14290506.643800.357501.923301.34240HepG2FXR1
ZNF274ENSG00000171606.13885.53770470.031700.913709.893608.67410HepG2G3BP1
ZNF274ENSG00000171606.13679.26930498.939700.445002.839301.93580HepG2G3BP2
ZNF274ENSG00000171606.13584.19690416.707800.487302.916001.86910HepG2GNB2L1
ZNF274ENSG00000171606.13658.42680476.069800.467804.923203.65880HepG2HDGF
ZNF274ENSG00000171606.13636.59120436.142800.545504.063503.23510HepG2HNRNPC
ZNF274ENSG00000171606.13709.71210475.844000.576604.553003.67590HepG2HNRNPK
ZNF274ENSG00000171606.13574.65900349.498100.717305.733304.86020HepG2HNRNPLL
ZNF274ENSG00000171606.13976.42930477.793001.0310013.2617011.90800HepG2IGF2BP2
ZNF274ENSG00000171606.13876.48010448.323300.967104.338803.11220HepG2IGF2BP3
ZNF274ENSG00000171606.13662.13260442.557400.581207.905806.73440HepG2ILF2
ZNF274ENSG00000171606.13736.86340480.548000.616603.904002.69540HepG2KHSRP
ZNF274ENSG00000171606.13713.90930506.820300.494203.277802.56420HepG2MAGOH
ZNF274ENSG00000171606.13654.09740467.834000.483403.788502.84500HepG2MSI2
ZNF274ENSG00000171606.13852.56050634.652100.425703.868802.96680HepG2NOL12
ZNF274ENSG00000171606.13799.12900464.649400.782207.560306.38090HepG2PABPC4
ZNF274ENSG00000171606.13615.07860424.290100.535602.737301.70290HepG2PCBP2
ZNF274ENSG00000171606.13595.79260437.908200.444104.034903.11900HepG2PRPF4
ZNF274ENSG00000171606.13578.49320281.119601.0410010.500409.05710HepG2PRPF8
ZNF274ENSG00000171606.13947.31730605.814500.644907.050906.15620HepG2PUF60
ZNF274ENSG00000171606.13848.74980642.621900.401303.274602.54520HepG2PUM2
ZNF274ENSG00000171606.13821.05510536.490300.613806.995106.06680HepG2QKI
ZNF274ENSG00000171606.13978.86120409.483701.2572010.451409.14850HepG2RAVER1
ZNF274ENSG00000171606.132118.80830741.390301.5148060.7548058.95650HepG2RBM22
ZNF274ENSG00000171606.13831.98730486.909000.772809.605608.40430HepG2RBM25
ZNF274ENSG00000171606.13640.51020513.486100.318802.346701.77270HepG2RECQL
ZNF274ENSG00000171606.13848.98770612.952700.469903.714802.94220HepG2RPLP0
ZNF274ENSG00000171606.13562.40790402.176000.483702.185801.34420HepG2RPS10
ZNF274ENSG00000171606.13621.01140278.093201.1590012.0288010.57540HepG2RRP9
ZNF274ENSG00000171606.131288.17400635.701301.0188010.952909.54820HepG2SF3A3
ZNF274ENSG00000171606.13574.42030345.946100.731506.404805.36830HepG2SF3B1
ZNF274ENSG00000171606.13671.42890515.739800.380503.158702.53200HepG2SF3B4
ZNF274ENSG00000171606.13577.37780449.931400.359703.075802.40220HepG2SMN1
ZNF274ENSG00000171606.131543.56350837.375300.8822024.6444023.53740HepG2SRFBP1
ZNF274ENSG00000171606.13423.30420538.32940-0.346802.232401.79580HepG2SRSF1
ZNF274ENSG00000171606.13533.34920372.205000.518902.615901.64550HepG2SRSF3
ZNF274ENSG00000171606.131058.02210598.130600.8227016.2270014.88930HepG2SRSF5
ZNF274ENSG00000171606.13671.35540437.967200.616207.949607.10000HepG2SRSF9
ZNF274ENSG00000171606.13898.65640727.043800.305602.955902.42970HepG2SSB
ZNF274ENSG00000171606.13548.19530386.101500.505602.882701.62440HepG2STAU1
ZNF274ENSG00000171606.13522.36680362.694900.526203.079402.36990HepG2SUPV3L1
ZNF274ENSG00000171606.13712.75320483.895700.558606.034705.25970HepG2TAF15
ZNF274ENSG00000171606.13451.83730340.597100.407602.155701.50340HepG2TARDBP
ZNF274ENSG00000171606.13587.46450424.757600.467804.541303.85520HepG2TRIM56
ZNF274ENSG00000171606.131245.18610494.460401.3323023.9812022.07100HepG2U2AF1
ZNF274ENSG00000171606.13934.29670626.415500.576703.983802.96870HepG2UBE2L3
ZNF274ENSG00000171606.13308.05100214.270500.523602.806202.04070HepG2UCHL5
ZNF274ENSG00000171606.13689.54070563.768300.290402.281101.63680HepG2UPF1
ZNF274ENSG00000171606.13472.41390332.177300.508002.427801.49150HepG2UPF2
ZNF274ENSG00000171606.13658.01720544.298600.273601.875901.36210HepG2UTP3
ZNF274ENSG00000171606.13486.02210357.032600.444902.490001.79920HepG2XRN2
ZNF274ENSG00000171606.13548.33460432.159900.343402.644401.98650HepG2ZC3H8
ZNF274ENSG00000171606.13919.21450620.039500.567909.387208.53190HepG2ZNF622
ZNF274ENSG00000171606.13923.93970667.171100.469604.134302.65520K562AARS
ZNF274ENSG00000171606.13863.947901414.09870-0.7109014.8412013.63640K562AGGF1
ZNF274ENSG00000171606.132125.307101701.727300.320602.676402.09660K562AQR
ZNF274ENSG00000171606.13809.41360616.821200.391902.503301.67570K562BOP1
ZNF274ENSG00000171606.13840.68960655.819200.358202.813102.02420K562CPSF6
ZNF274ENSG00000171606.132747.303302124.465000.370804.486103.23470K562CELF1
ZNF274ENSG00000171606.131645.965701173.472800.488008.417607.36190K562DDX47
ZNF274ENSG00000171606.131089.76530783.945100.475103.442101.53790K562DDX51
ZNF274ENSG00000171606.131256.834901583.46500-0.333304.045802.95920K562DKC1
ZNF274ENSG00000171606.131175.36780751.134100.645904.943303.19250K562EEF2
ZNF274ENSG00000171606.131007.63060725.683700.473503.758602.68210K562EFTUD2
ZNF274ENSG00000171606.131100.36620776.887200.502103.516302.33720K562EIF3D
ZNF274ENSG00000171606.13917.73170758.901000.274101.989401.30540K562EIF3G
ZNF274ENSG00000171606.131012.01360740.216800.451103.998403.01360K562EIF4A3
ZNF274ENSG00000171606.13945.23600769.796600.296102.579601.99120K562FXR1
ZNF274ENSG00000171606.131243.75040931.733500.416604.126502.81700K562HNRNPA1
ZNF274ENSG00000171606.131419.72430730.009700.9595017.5805016.15730K562HNRNPC
ZNF274ENSG00000171606.13719.39970534.705200.427902.134201.32640K562KRR1
ZNF274ENSG00000171606.131322.067801749.38240-0.404004.545703.31940K562MBNL1
ZNF274ENSG00000171606.13933.670301226.18460-0.393202.196801.43110K562NAA15
ZNF274ENSG00000171606.13997.00640706.176300.497503.934503.04170K562PRPF8
ZNF274ENSG00000171606.132450.137501885.076800.378103.594402.66730K562PUF60
ZNF274ENSG00000171606.13871.972501459.37350-0.743005.569304.83040K562PUS1
ZNF274ENSG00000171606.13950.595501421.82900-0.580808.897607.86070K562RBM15
ZNF274ENSG00000171606.131146.29580884.703200.373602.964202.09170K562RBM22
ZNF274ENSG00000171606.13745.07070597.180600.319102.260101.36900K562RCC2
ZNF274ENSG00000171606.131094.32800719.247400.605404.816303.73560K562RPS19
ZNF274ENSG00000171606.13809.09940664.181200.284602.003601.32070K562U2AF2
ZNF274ENSG00000171606.131298.796301114.995700.220001.978301.36410K562UPF1
ZNF274ENSG00000171606.131274.81030954.073100.418004.071803.00260K562WDR3
ZNF274ENSG00000171606.131247.63430992.081200.330604.152103.13070K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ZNF274 is not available on ENCORE database.





10 RBPs can affect the splicing of ZNF274 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEZNF274ENSG00000171606.13chr19+587215745872175358721326587214395872292558723052-0.059000.001070.02169excludedHepG2U2AF1
SEZNF274ENSG00000171606.13chr19+587213265872143958718363587185685872292558723052-0.099000.011110.08828excludedK562AQR
SEZNF274ENSG00000171606.13chr19+587215745872179658721326587214395872292558723052-0.128000.002860.08594excludedK562FXR1
SEZNF274ENSG00000171606.13chr19+5872157458721796587213265872143958722925587230520.240000.000110.00522includedHepG2SF3A3
SEZNF274ENSG00000171606.13chr19+587215745872179658721326587214395872292558723052-0.097000.000360.05998excludedK562EIF4G2
SEZNF274ENSG00000171606.13chr19+5872157458721796587213265872143958722925587230520.146000.001890.04543includedK562AGGF1
SEZNF274ENSG00000171606.13chr19+587215745872179658721326587214395872292558723052-0.089000.000510.07101excludedK562ZC3H8
SEZNF274ENSG00000171606.13chr19+5872157458721796587213265872143958722925587230520.261000.000810.05201includedHepG2SRSF9
SEZNF274ENSG00000171606.13chr19+587215745872179658721326587214395872292558723052-0.157000.003210.09536excludedK562PTBP1
SEZNF274ENSG00000171606.13chr19+587213265872143958718363587185685872292558723052-0.233000.003020.04685excludedK562HNRNPC
A3SSZNF274ENSG00000171606.13chr19+5869706358697205586970785869720558695287586953650.176000.000820.03881longerK562U2AF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ZNF274 is not avaliable on ENCORE database.