XPC

General Information

Gene Name       : XPC
Gene ID             : ENSG00000154767.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: XPC)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878XPCENSG00000154767.1419.8624.7122.29ENCSR000AEF
HepG2XPCENSG00000154767.1419.1419.5819.36ENCSR985KAT
K562XPCENSG00000154767.1439.3136.8238.06ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for XPC is not avaliable on ENCORE database.



Proteins bound to RNA
  • XPC RNA is bound by 22 proteins.  







eCLIP assay for XPC is not avaliable on ENCORE database.





22 proteins are bound to XPC RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr31420011714200191-3'-UTR,CDS,intron-Distal3.857208.25234K562ZNF622
chr31419376314193837-3'-UTR,CDS,intron-Distal,intron-Proximal4.428164.85612K562PRPF8
chr31420008914200154-3'-UTR,CDS,intron-Distal3.646806.77066K562UCHL5
chr31420006414200164-3'-UTR,CDS,intron-Distal4.831096.94886HepG2GRWD1
chr31419965014199756-3'-UTR,CDS,intron-Distal5.115828.49462K562FXR2
chr31419968414199789-3'-UTR,CDS,intron-Distal4.409299.69911HepG2GRWD1
chr31418702414187102-3'-UTR,intron-Distal4.523919.03593K562LIN28B
chr31419946314199546-3'-UTR,CDS,intron-Distal,intron-Proximal3.8707412.22234HepG2PRPF8
chr31420010214200255-3'-UTR,CDS,intron-Distal,intron-Proximal3.306148.58857K562ZNF800
chr31419031314190350-3'-UTR,CDS,intron-Distal,intron-Proximal3.239304.51003HepG2PPIG
chr31420022614200272-3'-UTR,CDS,intron-Distal,intron-Proximal4.670815.14565K562UCHL5
chr31419970214199759-3'-UTR,CDS,intron-Distal3.625025.76403K562UCHL5
chr31420009814200140-3'-UTR,CDS,intron-Distal3.543453.59112HepG2PPIG
chr31419970214199791-3'-UTR,CDS,intron-Distal4.281265.29232K562GRWD1
chr31419986914199930-3'-UTR,CDS,intron-Distal3.289335.39086K562UCHL5
chr31420013714200234-3'-UTR,CDS,intron-Distal,intron-Proximal4.053536.58643K562PUM1
chr31419384014193917-3'-UTR,CDS,intron-Distal,intron-Proximal3.008884.16939HepG2PPIG
chr31420022014200267-3'-UTR,CDS,intron-Distal,intron-Proximal3.320733.63681K562RBM15
chr31420005514200179-3'-UTR,CDS,intron-Distal4.336523.31335K562MTPAP
chr31420015914200226-3'-UTR,CDS,intron-Distal,intron-Proximal5.637459.91399K562UCHL5
chr31419970014199910-3'-UTR,CDS,intron-Distal3.6570110.62736K562ZNF622
chr31419778314197857-3'-UTR,CDS,intron-Distal,intron-Proximal3.403838.80228HepG2PRPF8
chr31419969414199761-3'-UTR,CDS,intron-Distal4.281395.79432HepG2BCLAF1
chr31419950314199536-3'-UTR,CDS,intron-Distal,intron-Proximal3.617364.40383K562UCHL5
chr31418884614188899-3'-UTR,CDS,intron-Distal,intron-Proximal3.116374.05586HepG2U2AF2
chr31419020614190232-3'-UTR,CDS,intron-Distal,intron-Proximal4.139423.25521K562LIN28B
chr31418678814186857-3'-UTR,intron-Distal4.010183.31330K562UPF1
chr31419379114193855-3'-UTR,CDS,intron-Distal,intron-Proximal3.525149.23918HepG2PRPF8
chr31420692714207020-5'-UTR,CDS,intron-Distal,intron-Proximal3.763476.02304HepG2GRWD1
chr31420692714206974-5'-UTR,CDS,intron-Distal,intron-Proximal4.531784.84481HepG2PPIG
chr31420625214206340-5'-UTR,CDS,intron-Distal,intron-Proximal3.890415.55177K562PRPF8
chr31420706914207084-5'-UTR,CDS,intron-Distal3.876013.56019HepG2GRWD1
chr31420869614208730-5'-UTR,CDS,intron-Distal3.805545.77244K562UCHL5
chr31420866914208725-5'-UTR,CDS,intron-Distal4.331374.01763HepG2GRWD1
chr31420701614207036-5'-UTR,CDS,intron-Distal3.559403.90826K562ZNF622
chr31420631014206349-5'-UTR,CDS,intron-Distal,intron-Proximal3.063613.07714K562YBX3
chr31420629514206334-5'-UTR,CDS,intron-Distal,intron-Proximal5.072513.37645HepG2PRPF8
chr31420704914207110-5'-UTR,CDS,intron-Distal,intron-Proximal3.436383.55754HepG2U2AF2
chr31420631514206350-5'-UTR,CDS,intron-Distal,intron-Proximal3.848783.56019HepG2GRWD1
chr31420860014208681-5'-UTR,CDS,intron-Distal,intron-Proximal5.416118.83608K562AQR
chr31420980414209882-CDS,intron-Distal,intron-Proximal3.229546.16215HepG2BUD13
chr31420981314209880-CDS,intron-Distal,intron-Proximal3.152205.21580K562GRWD1
chr31421193414212010-CDS,intron-Distal,intron-Proximal3.064985.32969HepG2PPIG
chr31421445314214481-CDS,intron-Distal3.822433.00996K562BUD13
chr31421444414214495-CDS,intron-Distal3.643723.77463K562ZNF800
chr31421437314214431-CDS,intron-Distal3.365125.23038K562ZNF622
chr31421991914219970-CDS,intron-Distal4.772485.68502HepG2PRPF8
chr31421449714214533-CDS,intron-Distal3.469143.87469HepG2BCLAF1
chr31420981114209880-CDS,intron-Distal,intron-Proximal3.821417.65975HepG2BCLAF1
chr31421450614214556-CDS,intron-Distal4.331788.58706K562UCHL5
chr31421444714214495-CDS,intron-Distal4.023383.34184HepG2GRWD1
chr31421199214212028-CDS,intron-Distal,intron-Proximal3.617363.12941K562UCHL5
chr31421193714212018-CDS,intron-Distal,intron-Proximal3.676096.11404K562PUM1
chr31421197214212047-CDS,intron-Distal,intron-Proximal4.436848.85033K562ZNF622
chr31420982014209881-CDS,intron-Distal,intron-Proximal4.308005.64870K562DDX24
chr31421446314214497-CDS,intron-Distal3.784184.79276K562ZNF622
chr31421451314214563-CDS,intron-Distal,intron-Proximal3.539084.74755K562ZNF622
chr31421193614211965-CDS,intron-Distal,intron-Proximal3.409846.32494K562UCHL5
chr31420982314209881-CDS,intron-Distal,intron-Proximal3.180614.40248K562PUM1
chr31421450714214562-CDS,intron-Distal3.405334.88141HepG2GRWD1
chr31420980114209880-CDS,intron-Distal,intron-Proximal3.371087.55111K562UCHL5
chr31421196514211992-CDS,intron-Distal,intron-Proximal3.940396.11943K562UCHL5
chr31420384414203904-intron-Distal4.180034.53347HepG2SUGP2
chr31418927414189337-intron-Distal,intron-Proximal4.626927.37772HepG2EFTUD2
chr31421180214211876-intron-Distal,intron-Proximal3.469394.23459K562PRPF8
chr31419375014193823-intron-Distal,intron-Proximal4.467836.67793HepG2EFTUD2
chr31420294214203006-intron-Distal3.946883.06150K562KHSRP
chr31420491014205021-intron-Distal3.747946.48117K562KHSRP
chr31420793414207997-intron-Distal4.359903.77360K562GTF2F1
chr31420283214202936-intron-Distal4.566876.13339K562KHSRP
chr31418932914189408-intron-Distal,intron-Proximal5.484569.23760K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for XPC is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for XPC is not available on ENCORE database.

  • 87 RBPs can affect the levels of XPC.  








The Knockdown/knockout RNA-Seq assay for XPC is not available on ENCORE database.





87 RBPs can affect the gene expression of XPC :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
XPCENSG00000154767.101468.841601078.434400.445603.515802.45820HepG2ABCF1
XPCENSG00000154767.101297.82210931.812800.477908.004407.07890HepG2ACO1
XPCENSG00000154767.102300.490001157.058700.9914013.4196012.33960HepG2AKAP1
XPCENSG00000154767.10764.732301050.50430-0.458103.871003.17540HepG2BOP1
XPCENSG00000154767.102113.850201394.488100.600004.891003.58290HepG2CCAR1
XPCENSG00000154767.101309.99180909.571900.526204.708303.71460HepG2CIRBP
XPCENSG00000154767.101166.51440931.756100.324104.083803.30550HepG2CKAP4
XPCENSG00000154767.101335.27220687.424200.957807.956006.66880HepG2CNOT7
XPCENSG00000154767.10877.11580519.094600.756707.723206.06850HepG2CSTF2
XPCENSG00000154767.101080.34960861.860400.325903.996403.01640HepG2DDX19B
XPCENSG00000154767.101071.55800843.211000.345602.552101.89730HepG2DDX21
XPCENSG00000154767.10704.11850952.08820-0.435302.557601.96280HepG2DDX6
XPCENSG00000154767.101214.19810891.530100.445505.994905.07060HepG2DKC1
XPCENSG00000154767.101060.06060796.381600.412503.853702.60620HepG2EIF3G
XPCENSG00000154767.101956.660301011.546800.9517012.6040011.26800HepG2EIF4A3
XPCENSG00000154767.102041.517101681.789400.279503.640202.96540HepG2ETF1
XPCENSG00000154767.101463.765401088.980000.426602.811402.03380HepG2FIP1L1
XPCENSG00000154767.101366.149101020.543100.420703.165502.42590HepG2FXR1
XPCENSG00000154767.101410.559501005.038500.488904.239003.12680HepG2G3BP2
XPCENSG00000154767.101124.71660887.828400.341102.275501.35520HepG2GNB2L1
XPCENSG00000154767.101118.82670636.332100.814006.480104.77930HepG2GRSF1
XPCENSG00000154767.101086.36120681.154300.673407.920906.91110HepG2HNRNPA1
XPCENSG00000154767.101211.14360757.660000.676608.042206.90580HepG2HNRNPC
XPCENSG00000154767.10857.28740595.435900.525703.163301.54130HepG2HNRNPD
XPCENSG00000154767.10459.44440958.57750-1.0610014.7831013.29320HepG2HNRNPK
XPCENSG00000154767.101143.08140752.650700.6028010.562409.44180HepG2HNRNPU
XPCENSG00000154767.101343.72200962.350400.481504.076703.27170HepG2IGF2BP2
XPCENSG00000154767.101096.76200670.140900.710605.161903.33010HepG2ILF3
XPCENSG00000154767.10887.66610654.897300.438602.547501.41570HepG2KHDRBS1
XPCENSG00000154767.101457.139701017.100400.518603.284601.91890HepG2KRR1
XPCENSG00000154767.101440.105801020.899100.496204.135303.33640HepG2MAGOH
XPCENSG00000154767.101769.831301026.623500.785608.759507.68780HepG2MATR3
XPCENSG00000154767.10626.79380881.43750-0.491904.161003.17900HepG2MSI2
XPCENSG00000154767.101456.876201230.241400.243801.976501.32870HepG2NOL12
XPCENSG00000154767.10945.56780744.993100.343903.426602.49360HepG2PARN
XPCENSG00000154767.101539.837201174.358800.390803.639002.96730HepG2PUF60
XPCENSG00000154767.101422.354001246.616900.190201.902601.39060HepG2PUM1
XPCENSG00000154767.101305.515701051.080900.312602.894402.25840HepG2QKI
XPCENSG00000154767.101937.302201405.673800.462707.321106.57180HepG2RBM22
XPCENSG00000154767.10711.95920953.94000-0.422103.618402.85450HepG2RBM25
XPCENSG00000154767.101457.343501080.106800.432106.104905.35380HepG2NELFE
XPCENSG00000154767.101217.165001006.003700.274802.717702.10590HepG2RECQL
XPCENSG00000154767.102107.782001462.281400.527406.649505.65520HepG2RPLP0
XPCENSG00000154767.101315.28180818.416900.684404.763803.53900HepG2RPS10
XPCENSG00000154767.101407.20800658.478901.0955022.1307020.65530HepG2RPS19
XPCENSG00000154767.101686.33420967.197500.8019011.5750010.03310HepG2RPS2
XPCENSG00000154767.101431.20460690.161901.0521011.6902010.09050HepG2RPS3A
XPCENSG00000154767.10800.36790670.267700.255802.124401.54690HepG2SAFB2
XPCENSG00000154767.10881.199301144.98660-0.377802.109101.51920HepG2SF3A3
XPCENSG00000154767.101268.164701010.426200.327703.676403.00840HepG2SF3B4
XPCENSG00000154767.101178.95490781.643700.5928011.9547010.76360HepG2SMN1
XPCENSG00000154767.101911.240601149.082600.733905.579804.45890HepG2SNRNP70
XPCENSG00000154767.102030.434701587.672800.354805.894905.23960HepG2SRFBP1
XPCENSG00000154767.101477.785301054.681300.486508.113207.40190HepG2SRSF1
XPCENSG00000154767.101803.795901159.488100.6374014.2765013.01040HepG2SRSF5
XPCENSG00000154767.101912.905901378.503800.472609.372308.53690HepG2SSB
XPCENSG00000154767.101372.543901014.296000.436303.047701.70170HepG2SSRP1
XPCENSG00000154767.101783.312001318.674700.435408.138907.16750HepG2SUCLG1
XPCENSG00000154767.101355.23550822.732200.719906.065805.12350HepG2SUPV3L1
XPCENSG00000154767.101213.35690948.030400.355903.753003.11660HepG2TAF15
XPCENSG00000154767.10781.076601016.85050-0.380602.744802.02300HepG2TARDBP
XPCENSG00000154767.101478.63500731.334201.0156022.9812021.80180HepG2TIAL1
XPCENSG00000154767.101459.744701147.271400.347403.104502.17450HepG2TUFM
XPCENSG00000154767.101303.24730980.355900.410605.863205.04570HepG2UTP3
XPCENSG00000154767.101170.21200809.892100.530903.702802.87220HepG2XRN2
XPCENSG00000154767.10775.593701116.77650-0.526009.472808.61370HepG2ZNF622
XPCENSG00000154767.101711.531601336.248200.357003.173601.89670K562AARS
XPCENSG00000154767.101327.424502175.16230-0.7125018.5059017.15930K562AGGF1
XPCENSG00000154767.101686.678802263.36190-0.424304.359303.53250K562AKAP8L
XPCENSG00000154767.101806.263102482.01150-0.458504.822304.08640K562AQR
XPCENSG00000154767.101088.513801457.97870-0.421602.581401.34860K562EEF2
XPCENSG00000154767.10933.853101408.65300-0.593006.399504.96310K562EFTUD2
XPCENSG00000154767.10891.610701508.17200-0.758307.927706.02790K562EIF3D
XPCENSG00000154767.102780.889403319.18830-0.255303.274702.25540K562EIF4G2
XPCENSG00000154767.10990.264701412.27600-0.512104.495202.64580K562GEMIN5
XPCENSG00000154767.102169.971602690.35840-0.310102.966702.18480K562GRSF1
XPCENSG00000154767.101644.617902817.35950-0.776602.494501.35470K562HNRNPA2B1
XPCENSG00000154767.10761.034701566.18170-1.0412016.5172013.52490K562HNRNPK
XPCENSG00000154767.101098.068701389.18690-0.339302.123301.31430K562HNRNPM
XPCENSG00000154767.101539.501902104.25250-0.450806.786305.38500K562HNRNPU
XPCENSG00000154767.101201.600502465.93370-1.037203.488502.34000K562PABPN1
XPCENSG00000154767.10915.723401466.37980-0.679308.936407.14780K562PCBP2
XPCENSG00000154767.101763.754301373.775300.360403.956102.99290K562POLR2G
XPCENSG00000154767.10744.959001370.78330-0.8798012.1818010.60040K562PRPF8
XPCENSG00000154767.101446.577102244.58430-0.633807.899007.02890K562PUS1
XPCENSG00000154767.101683.719502187.05040-0.377304.805904.04450K562RBM15
XPCENSG00000154767.102081.296001615.662400.365302.982801.84360K562NELFE
XPCENSG00000154767.101097.164401396.24730-0.347802.092501.38630K562RPS19
XPCENSG00000154767.101920.149602266.55380-0.239302.583101.79460K562SF3A3
XPCENSG00000154767.10925.823101160.70580-0.326202.835301.97010K562SF3B4
XPCENSG00000154767.101908.485801569.869600.281702.485301.80870K562SRSF1
XPCENSG00000154767.10918.894601260.94760-0.456503.513402.45380K562TIAL1
XPCENSG00000154767.102251.985802684.60170-0.253503.590502.13510K562TROVE2
XPCENSG00000154767.10800.716801082.09110-0.434502.882601.76370K562U2AF1
XPCENSG00000154767.10874.733501117.41140-0.353203.182502.32240K562U2AF2
XPCENSG00000154767.101739.632702084.01900-0.260602.198701.41900K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for XPC is not available on ENCORE database.





9 RBPs can affect the splicing of XPC :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEXPCENSG00000154767.10chr3-1419537814195533141938341419391614197834141979950.099000.000680.02803includedK562PRPF8
SEXPCENSG00000154767.10chr3-1419537814195533141938341419391614197834141979950.611000.000000.00000includedHepG2HNRNPK
SEXPCENSG00000154767.10chr3-142012401420133014199510142003921420631214206433-0.052000.004100.04540excludedHepG2U2AF2
SEXPCENSG00000154767.10chr3-1419537814195533141938341419391614197834141979950.074000.000250.03886includedK562RBM22
SEXPCENSG00000154767.10chr3-1419537814195533141938341419391614197834141979950.068000.003480.05431includedK562U2AF2
SEXPCENSG00000154767.10chr3-1419537814195533141938341419391614197834141979950.058000.001390.04843includedK562TARDBP
SEXPCENSG00000154767.10chr3-142097561420988014208668142087531421193714212114-0.075000.000900.03488excludedK562HNRNPU
SEXPCENSG00000154767.10chr3-1419537814195533141938341419391614197834141979950.228000.000000.00000includedK562HNRNPK
SEXPCENSG00000154767.10chr3-1418905814189279141887891418887914189407141895010.091000.000040.00342includedK562HNRNPK
SEXPCENSG00000154767.10chr3-142097561420988014208668142087531421193714212114-0.116000.000120.00307excludedK562HNRNPC
A3SSXPCENSG00000154767.10chr3-1418940714189608141894071418950114190061141902310.119000.000000.00000longerK562AQR
MXEXPCENSG00000154767.10chr3-14193834141939161419783414197995141903131419044814199510142003920.126000.002670.058821includedK562SBDS

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for XPC is not avaliable on ENCORE database.