TPST2

General Information

Gene Name       : TPST2
Gene ID             : ENSG00000128294.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TPST2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TPST2ENSG00000128294.157.2011.169.18ENCSR000AEF
HepG2TPST2ENSG00000128294.1511.417.369.38ENCSR985KAT
K562TPST2ENSG00000128294.1546.7340.4343.58ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TPST2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TPST2 RNA is bound by 36 proteins.  







eCLIP assay for TPST2 is not avaliable on ENCORE database.





36 proteins are bound to TPST2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr222692412126924231-3'-UTR,CDS,intron-Distal,intron-Proximal6.3400212.49766HepG2PRPF8
chr222692186326921957-3'-UTR,intron-Distal3.392293.28764HepG2LARP4
chr222693763226937687-3'-UTR,intron-Distal,intron-Proximal4.006738.04211K562DDX3X
chr222693197126932091-3'-UTR,CDS,intron-Distal5.733568.10458K562QKI
chr222694060026940641-3'-UTR,intron-Distal4.656819.60311HepG2DDX3X
chr222694056826940643-3'-UTR,intron-Distal,intron-Proximal3.4739114.07909K562DDX3X
chr222692193226921977-3'-UTR,intron-Distal3.251583.77680K562TIA1
chr222692176726921815-3'-UTR,intron-Distal4.200499.63547K562PABPC4
chr222692172426921767-3'-UTR,intron-Distal5.521279.39648K562PABPC4
chr222692414126924187-3'-UTR,intron-Distal,intron-Proximal5.2703139.76569K562PRPF8
chr222694060226940695-3'-UTR,intron-Distal,intron-Proximal3.391134.94119K562SF3B4
chr222692221426922281-3'-UTR,intron-Distal3.286464.42622K562SMNDC1
chr222692412226924182-3'-UTR,intron-Distal,intron-Proximal3.544745.37841K562SF3B4
chr222693192926931971-3'-UTR,intron-Distal3.553914.56634K562QKI
chr222692417326924185-3'-UTR,intron-Distal,intron-Proximal4.3509122.31683K562AQR
chr222692219826922280-3'-UTR,intron-Distal3.7834512.09266K562SF3B4
chr222698601626986085-5'-UTR,intron-Distal4.9520116.67528HepG2DDX3X
chr222692866026928696-CDS,intron-Distal,intron-Proximal3.463186.18351K562YBX3
chr222693670626936777-CDS,intron-Distal,intron-Proximal3.101985.78875K562PRPF8
chr222692858426928662-CDS,intron-Distal,intron-Proximal4.281029.78712K562AQR
chr222692866626928722-CDS,intron-Distal,intron-Proximal3.137454.81603K562BUD13
chr222693753626937581-CDS,intron-Distal4.266234.66990HepG2DDX3X
chr222693694826937001-CDS,intron-Distal4.267633.98353K562RBM15
chr222693217626932254-CDS,intron-Distal,intron-Proximal4.5964012.85453K562AQR
chr222693743226937502-CDS,intron-Distal,intron-Proximal3.131503.94558HepG2DDX3X
chr222693225226932262-CDS,intron-Distal,intron-Proximal3.566518.67507K562YBX3
chr222692869626928711-CDS,intron-Distal4.2012410.21839K562YBX3
chr222693676626936861-CDS,intron-Distal,intron-Proximal3.813683.49838K562SND1
chr222693693026937013-CDS,intron-Distal,intron-Proximal3.110197.43928K562YBX3
chr222698556126985610-intron-Distal4.157063.82910K562NONO
chr222697691626976993-intron-Distal5.0794231.17771K562EIF4G2
chr222697568426975840-intron-Distal3.797874.56984HepG2PTBP1
chr222698589426985991-intron-Distal3.073383.89482K562CSTF2T
chr222697702426977061-intron-Distal3.238533.89328K562EIF4G2
chr222696828426968332-intron-Distal3.829404.37763K562DGCR8
chr222698020726980287-intron-Distal4.578064.76505K562HNRNPK
chr222696413826964251-intron-Distal3.723513.24603K562KHSRP
chr222698593226985987-intron-Distal5.277915.60708K562DDX52
chr222698589126985998-intron-Distal4.505309.40313K562NONO
chr222697692526976985-intron-Distal4.482194.43679K562IGF2BP1
chr222694437426944438-intron-Distal5.4869027.72060K562PTBP1
chr222698590126985985-intron-Distal4.417985.87587K562GEMIN5
chr222697568826975750-intron-Distal4.8584519.27960K562PTBP1
chr222698546826985515-intron-Distal3.452833.77708K562GTF2F1
chr222698590226985998-intron-Distal5.471097.20890K562GTF2F1
chr222698547426985520-intron-Distal4.728155.59615K562NONO
chr222696659926966650-intron-Distal4.063193.29548K562TAF15
chr222692411326924173-intron-Distal,intron-Proximal4.8876331.82588K562AQR
chr222694438626944464-intron-Distal3.412614.19039HepG2PTBP1
chr222698580426985878-intron-Distal4.247873.02324K562XRN2
chr222693530526935415-intron-Distal3.786064.25479HepG2PCBP2
chr222693373626933801-intron-Distal3.923175.91510K562TARDBP
chr222693530026935439-intron-Distal3.517104.90594K562HNRNPK
chr222698591526985970-intron-Distal4.585225.01284K562NCBP2
chr222695151026951628-intron-Distal4.395744.08332K562NONO
chr222698564126985692-intron-Distal4.597746.40665K562NONO
chr222698547626985571-intron-Distal3.400243.93915K562EWSR1
chr222697702026977089-intron-Distal4.171714.38266K562TARDBP
chr222696774626967840-intron-Distal3.769963.19850K562FUS
chr222692407626924141-intron-Distal,intron-Proximal3.2293810.14566K562PRPF8
chr222697575026975847-intron-Distal4.0331419.12382K562PTBP1
chr222698573726985795-intron-Distal4.978758.79830K562NONO
chr222695162826951787-intron-Distal4.140037.56813K562NONO
chr222696417426964249-intron-Distal3.949953.31905K562NONO
chr222693534826935437-intron-Distal3.841795.16954K562PCBP1
chr222696427226964323-intron-Distal4.728155.59615K562NONO
chr222697524426975315-intron-Distal3.316463.52502K562ILF3
chr222692406226924149-intron-Distal,intron-Proximal4.486318.21563K562RBM22
chr222696773126967790-intron-Distal3.519033.41711K562DROSHA
chr222697693126977009-intron-Distal4.628636.71516K562TARDBP
chr222698589826985985-intron-Distal3.789834.83282K562EFTUD2
chr222697016926970264-intron-Distal3.294263.61097K562ILF3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TPST2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TPST2 is not available on ENCORE database.

  • 74 RBPs can affect the levels of TPST2.  








The Knockdown/knockout RNA-Seq assay for TPST2 is not available on ENCORE database.





74 RBPs can affect the gene expression of TPST2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TPST2ENSG00000128294.1186.99170141.83260-0.705202.392401.39200HepG2AATF
TPST2ENSG00000128294.11146.99380200.30120-0.446401.910101.38770HepG2ACO1
TPST2ENSG00000128294.11107.47510185.17300-0.784903.484002.82100HepG2BOP1
TPST2ENSG00000128294.11190.80430326.34290-0.774304.740003.74280HepG2CIRBP
TPST2ENSG00000128294.11132.98390211.16280-0.667102.298301.60490HepG2CNOT7
TPST2ENSG00000128294.11258.28690185.261700.479302.841101.99660HepG2DDX19B
TPST2ENSG00000128294.11204.69840143.175100.515602.290901.64540HepG2DNAJC21
TPST2ENSG00000128294.11208.43040141.899100.554602.908602.24260HepG2DNAJC2
TPST2ENSG00000128294.11146.24550328.37710-1.167008.686907.67430HepG2EIF2S1
TPST2ENSG00000128294.1192.35040148.61930-0.686402.413501.56450HepG2EIF3D
TPST2ENSG00000128294.11202.28600353.36530-0.804804.088803.26080HepG2EIF4B
TPST2ENSG00000128294.11346.23460222.730900.636303.797402.85330HepG2EIF4G2
TPST2ENSG00000128294.11137.84880265.15510-0.943706.116104.97030HepG2FUBP3
TPST2ENSG00000128294.11225.14490366.22330-0.701904.125803.29290HepG2FXR1
TPST2ENSG00000128294.11140.71160339.66490-1.2714010.602609.34120HepG2G3BP1
TPST2ENSG00000128294.11149.19570216.59580-0.537802.434501.54980HepG2HNRNPA2B1
TPST2ENSG00000128294.11284.53410193.859500.553502.643001.94160HepG2HNRNPF
TPST2ENSG00000128294.11231.43440344.08380-0.572202.996002.27030HepG2HNRNPK
TPST2ENSG00000128294.1174.19880159.71490-1.106006.594205.69310HepG2HNRNPU
TPST2ENSG00000128294.11315.75660190.897800.725905.325204.35340HepG2IGF2BP1
TPST2ENSG00000128294.11216.93020345.24030-0.670403.690602.91940HepG2IGF2BP2
TPST2ENSG00000128294.11178.22870324.08040-0.862602.834501.84090HepG2IGF2BP3
TPST2ENSG00000128294.11220.62740347.29330-0.654503.207502.11730HepG2KHSRP
TPST2ENSG00000128294.11194.63080377.04550-0.954006.849905.87420HepG2NCBP2
TPST2ENSG00000128294.11114.90510188.13220-0.711302.566801.38910HepG2PRPF6
TPST2ENSG00000128294.1178.23250125.91120-0.686602.119501.40820HepG2PRPF8
TPST2ENSG00000128294.11177.09210326.69480-0.883407.718806.89610HepG2PTBP1
TPST2ENSG00000128294.11207.18940353.82110-0.772105.825504.96630HepG2QKI
TPST2ENSG00000128294.11122.69980302.87180-1.3036012.6750011.72820HepG2RBM22
TPST2ENSG00000128294.11183.39870363.58090-0.987309.074008.19680HepG2NELFE
TPST2ENSG00000128294.11254.70670338.62440-0.410802.223301.66400HepG2RECQL
TPST2ENSG00000128294.11302.26000208.811800.533502.776502.09250HepG2RPLP0
TPST2ENSG00000128294.11261.54170340.13360-0.379101.980201.46610HepG2SF3B4
TPST2ENSG00000128294.11221.08810342.08560-0.629704.773704.16700HepG2SRFBP1
TPST2ENSG00000128294.11193.19410355.02500-0.877907.618606.92550HepG2SRSF1
TPST2ENSG00000128294.11135.46500220.26420-0.701303.843503.12730HepG2SRSF5
TPST2ENSG00000128294.11284.55670190.455400.579203.825503.02670HepG2SRSF7
TPST2ENSG00000128294.11216.33820288.83100-0.416902.264801.75500HepG2SRSF9
TPST2ENSG00000128294.11235.85530356.23370-0.594902.878501.52360HepG2SUGP2
TPST2ENSG00000128294.1190.78780155.20740-0.773603.196002.66480HepG2TIAL1
TPST2ENSG00000128294.11331.72890189.995800.803904.631503.19980HepG2XPO5
TPST2ENSG00000128294.11207.00190273.58120-0.402302.119701.62250HepG2ZNF622
TPST2ENSG00000128294.111500.303601119.015200.422906.339805.53290K562AGGF1
TPST2ENSG00000128294.111811.880601164.386900.637808.405807.20530K562AKAP8L
TPST2ENSG00000128294.11789.676501745.24430-1.1441022.3205020.83640K562AQR
TPST2ENSG00000128294.111634.073101221.723800.419505.636804.28020K562ATP5C1
TPST2ENSG00000128294.11765.755901048.82780-0.453804.313503.33440K562CPSF6
TPST2ENSG00000128294.112075.781002736.62230-0.398705.717204.31670K562CELF1
TPST2ENSG00000128294.111380.839001764.06930-0.353405.098304.25160K562DDX47
TPST2ENSG00000128294.11669.18630960.02370-0.520702.672701.68820K562EIF3A
TPST2ENSG00000128294.11696.52040964.47600-0.469604.193403.18420K562EIF4A3
TPST2ENSG00000128294.111421.119801107.358300.359802.920402.04840K562FIP1L1
TPST2ENSG00000128294.11671.26390904.48600-0.430202.900201.96380K562FTO
TPST2ENSG00000128294.111125.153501365.91780-0.279702.563501.46760K562GLRX3
TPST2ENSG00000128294.11755.772601001.38090-0.406003.245102.38750K562GPKOW
TPST2ENSG00000128294.111258.210301732.41370-0.461405.054004.03230K562GRSF1
TPST2ENSG00000128294.11947.597501370.14250-0.532003.469002.26130K562HNRNPA1
TPST2ENSG00000128294.11837.987801275.49360-0.606107.472206.53690K562HNRNPC
TPST2ENSG00000128294.111062.747801517.44990-0.513804.903503.70150K562HNRNPU
TPST2ENSG00000128294.111757.079901384.299400.343903.315202.30250K562MBNL1
TPST2ENSG00000128294.111003.927201436.09700-0.516509.004407.62540K562MTPAP
TPST2ENSG00000128294.111380.876901595.56230-0.208502.456101.74850K562NSUN2
TPST2ENSG00000128294.11931.087101790.66080-0.9435010.307408.70870K562PCBP3
TPST2ENSG00000128294.11739.958201373.42830-0.8923013.0624011.38840K562POLR2G
TPST2ENSG00000128294.11525.32270734.41460-0.483402.825002.06810K562PRPF8
TPST2ENSG00000128294.111680.822302427.99100-0.530607.360006.02570K562PUF60
TPST2ENSG00000128294.112104.796502582.89490-0.295303.539502.32360K562PUM1
TPST2ENSG00000128294.111624.159001125.131300.529508.103107.11850K562RBM15
TPST2ENSG00000128294.111344.342601574.51750-0.228002.115201.39550K562SF3A3
TPST2ENSG00000128294.11694.11910952.31810-0.456303.023602.00590K562SF3B1
TPST2ENSG00000128294.11720.979001166.13910-0.693703.063301.65930K562SFPQ
TPST2ENSG00000128294.11705.120501098.50930-0.639602.613401.43240K562SNRNP200
TPST2ENSG00000128294.11875.505601428.33640-0.706103.397601.57290K562STIP1
TPST2ENSG00000128294.111068.030401377.68060-0.367302.532201.74890K562SYNCRIP
TPST2ENSG00000128294.11749.687501099.97360-0.553104.761203.50750K562TIAL1
TPST2ENSG00000128294.111258.190301505.42220-0.258803.038502.15300K562WDR43
TPST2ENSG00000128294.111620.879501966.11880-0.278602.218801.45720K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TPST2 is not available on ENCORE database.





8 RBPs can affect the splicing of TPST2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETPST2ENSG00000128294.11chr22-2694346526943584269405692694064126986016269860890.158000.000050.01670includedK562DROSHA
SETPST2ENSG00000128294.11chr22-269405692694064126932253269324522698601626986127-0.190000.000820.09156excludedK562LARP4
SETPST2ENSG00000128294.11chr22-2694346526943584269405692694064126986016269860890.197000.000270.07070includedK562PPIL4
SETPST2ENSG00000128294.11chr22-269434652694358426940569269406412698601626986089-0.250000.002490.07490excludedK562TARDBP
A3SSTPST2ENSG00000128294.11chr22-2693225326932470269322532693245226936754269376840.104000.000000.00002longerK562AQR
MXETPST2ENSG00000128294.11chr22-26932253269324522694056926940641269286602692871126986016269861270.303000.000010.000451includedK562SRSF1
MXETPST2ENSG00000128294.11chr22-2693225326932452269405692694064126928660269287112698601626986127-0.139000.002860.061442includedK562SBDS
MXETPST2ENSG00000128294.11chr22-26932253269324522694056926940641269286602692871126986016269861270.202000.000980.061421includedK562RBM22

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TPST2 is not avaliable on ENCORE database.