TMEM175

General Information

Gene Name       : TMEM175
Gene ID             : ENSG00000127419.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMEM175)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TMEM175ENSG00000127419.162.386.804.59ENCSR000AEF
HepG2TMEM175ENSG00000127419.166.461.784.12ENCSR985KAT
K562TMEM175ENSG00000127419.1615.565.7110.63ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMEM175 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMEM175 RNA is bound by 5 proteins.  







eCLIP assay for TMEM175 is not avaliable on ENCORE database.





5 proteins are bound to TMEM175 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr4941888941952+3'-UTR,CDS,intron-Distal,intron-Proximal3.362894.35314HepG2U2AF2
chr4946216946280+3'-UTR,CDS,intron-Proximal4.318174.84106K562EIF4G2
chr4941635941738+CDS,intron-Distal,intron-Proximal3.442918.43093HepG2PRPF8
chr4941671941735+CDS,intron-Distal,intron-Proximal5.5381411.11361K562PRPF8
chr4946395946425+intron-Distal4.601694.19739K562EIF4G2
chr4946667946710+intron-Distal5.373037.26071K562EIF4G2
chr4946771946836+intron-Distal4.377967.62986K562EIF4G2
chr4946455946513+intron-Distal5.170446.58769K562EIF4G2
chr4946560946628+intron-Distal3.389614.41411K562TARDBP
chr4946304946357+intron-Distal,intron-Proximal5.488698.53131K562EIF4G2
chr4949995950116+intron-Distal,intron-Proximal4.561965.59072HepG2HNRNPK
chr4946594946654+intron-Distal6.0415510.98400K562EIF4G2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMEM175 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMEM175 is not available on ENCORE database.

  • 112 RBPs can affect the levels of TMEM175.  








The Knockdown/knockout RNA-Seq assay for TMEM175 is not available on ENCORE database.





112 RBPs can affect the gene expression of TMEM175 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMEM175ENSG00000127419.12243.34620148.134500.716002.894501.93140HepG2ABCF1
TMEM175ENSG00000127419.12242.2222073.332401.7237010.171009.21720HepG2AKAP1
TMEM175ENSG00000127419.12201.31720102.480500.974004.792103.43420HepG2AKAP8
TMEM175ENSG00000127419.12201.28800142.198000.501302.212601.51850HepG2AKAP8L
TMEM175ENSG00000127419.12253.74850156.225000.699704.454003.61920HepG2AUH
TMEM175ENSG00000127419.12124.5061060.376101.044102.893101.93180HepG2BCCIP
TMEM175ENSG00000127419.12188.6867073.136101.367208.202607.23790HepG2BOP1
TMEM175ENSG00000127419.12245.95420141.724500.795203.591202.46550HepG2CCAR1
TMEM175ENSG00000127419.12101.4063057.643200.814802.207201.51200HepG2CIRBP
TMEM175ENSG00000127419.12247.36170141.503000.805705.724604.83070HepG2CKAP4
TMEM175ENSG00000127419.12128.8605056.463101.190304.066903.13290HepG2CNOT7
TMEM175ENSG00000127419.12108.7595067.285500.692702.453501.84090HepG2CELF1
TMEM175ENSG00000127419.12157.5102072.318701.122907.214006.09820HepG2DAZAP1
TMEM175ENSG00000127419.12200.3462070.234601.512109.000907.92800HepG2DDX3X
TMEM175ENSG00000127419.12147.1157059.367101.309104.689303.71010HepG2DDX55
TMEM175ENSG00000127419.12160.98050102.926300.645202.359801.42720HepG2DDX5
TMEM175ENSG00000127419.12144.1222060.362001.255505.275304.44780HepG2DDX6
TMEM175ENSG00000127419.12105.1789042.132301.319705.569404.60160HepG2DNAJC21
TMEM175ENSG00000127419.12117.8518041.759701.496708.156307.10960HepG2DNAJC2
TMEM175ENSG00000127419.12247.7343057.998602.0946017.6622016.25670HepG2EIF2S1
TMEM175ENSG00000127419.12221.6177064.081401.7900012.6816011.34050HepG2EIF4A3
TMEM175ENSG00000127419.12114.5484062.418800.875802.131601.52520HepG2EIF4B
TMEM175ENSG00000127419.12289.32610179.369900.689703.830103.14300HepG2ETF1
TMEM175ENSG00000127419.12107.1182054.346300.978803.083701.90490HepG2FUS
TMEM175ENSG00000127419.12168.7606064.697601.383107.169806.09150HepG2FXR1
TMEM175ENSG00000127419.12190.8459059.994301.6694010.847909.57350HepG2G3BP1
TMEM175ENSG00000127419.12143.1558076.099800.911503.192802.51000HepG2GPKOW
TMEM175ENSG00000127419.12107.8259052.288001.044103.287102.06700HepG2GRSF1
TMEM175ENSG00000127419.12113.2268042.535901.412405.466104.60170HepG2HNRNPA1
TMEM175ENSG00000127419.12146.0922047.313201.626504.299903.44950HepG2HNRNPC
TMEM175ENSG00000127419.12159.4100093.130500.775303.730002.90720HepG2HNRNPF
TMEM175ENSG00000127419.12197.7277060.801501.7012010.886709.58130HepG2HNRNPK
TMEM175ENSG00000127419.12121.7132065.867800.885704.013003.21310HepG2HNRNPL
TMEM175ENSG00000127419.12153.7570072.624201.082004.520103.73470HepG2HNRNPLL
TMEM175ENSG00000127419.12134.9040047.000401.521108.850907.81360HepG2HNRNPU
TMEM175ENSG00000127419.12161.7746091.707200.818803.874003.02880HepG2IGF2BP1
TMEM175ENSG00000127419.12148.2780060.975001.281905.850104.90550HepG2IGF2BP2
TMEM175ENSG00000127419.12103.9792048.009401.114804.921303.96530HepG2ILF2
TMEM175ENSG00000127419.12284.45530149.770200.925405.024503.89180HepG2LARP4
TMEM175ENSG00000127419.12187.3145064.720401.533109.010307.84080HepG2MAGOH
TMEM175ENSG00000127419.12169.1048065.075701.377606.522505.58550HepG2MATR3
TMEM175ENSG00000127419.12242.57890121.021701.003106.035504.88270HepG2MSI2
TMEM175ENSG00000127419.12260.1268066.603101.9655016.0813014.63820HepG2NCBP2
TMEM175ENSG00000127419.12139.7115071.712700.962004.748203.74990HepG2NOL12
TMEM175ENSG00000127419.12122.6433054.538601.169003.062201.90800HepG2NONO
TMEM175ENSG00000127419.12135.1777059.288801.188905.048604.08390HepG2PABPC4
TMEM175ENSG00000127419.1285.3028041.920601.024803.339402.53580HepG2PPIL4
TMEM175ENSG00000127419.12118.8458045.771101.376504.757303.72980HepG2PRPF8
TMEM175ENSG00000127419.12186.6737083.208001.165607.356806.54940HepG2PTBP1
TMEM175ENSG00000127419.12116.4793068.464300.766502.032401.50910HepG2PUF60
TMEM175ENSG00000127419.12171.7276072.687501.240208.899507.96450HepG2PUM1
TMEM175ENSG00000127419.12157.8316072.628401.119702.978402.28230HepG2PUM2
TMEM175ENSG00000127419.12293.47450144.157701.025509.486008.45930HepG2PUS1
TMEM175ENSG00000127419.12173.3184090.082700.944004.760503.97450HepG2QKI
TMEM175ENSG00000127419.12138.7555060.051101.208203.301402.21230HepG2RBM27
TMEM175ENSG00000127419.12177.9719092.589400.942604.844904.16440HepG2NELFE
TMEM175ENSG00000127419.12127.7393066.429800.943203.547702.86040HepG2RPS19
TMEM175ENSG00000127419.12141.3781055.366501.352404.832403.79290HepG2RPS2
TMEM175ENSG00000127419.12117.3812056.798401.047203.045902.20840HepG2RPS3A
TMEM175ENSG00000127419.12155.4537086.602000.843903.817003.14040HepG2SF3B4
TMEM175ENSG00000127419.12116.9649065.666400.832703.435802.66860HepG2SLBP
TMEM175ENSG00000127419.1288.8152048.811400.863502.572001.94830HepG2SMN1
TMEM175ENSG00000127419.12119.2747050.755701.232505.124603.79320HepG2SMNDC1
TMEM175ENSG00000127419.1288.7334030.797201.526603.201201.77020HepG2SNRNP200
TMEM175ENSG00000127419.12110.05990169.32760-0.621502.679402.18320HepG2SRFBP1
TMEM175ENSG00000127419.12122.4273067.610100.856503.638202.93830HepG2SRSF5
TMEM175ENSG00000127419.12202.00180147.014600.458301.956601.50630HepG2SSB
TMEM175ENSG00000127419.12200.3845076.881401.3820011.053009.95020HepG2SUCLG1
TMEM175ENSG00000127419.12109.5739059.091500.890801.998001.40940HepG2SUPV3L1
TMEM175ENSG00000127419.1240.7746081.29190-0.995402.419201.88940HepG2TAF15
TMEM175ENSG00000127419.12123.0236070.808500.796802.510101.81480HepG2TARDBP
TMEM175ENSG00000127419.12199.2629045.670302.125209.475408.64720HepG2TIAL1
TMEM175ENSG00000127419.12152.9987046.077901.7313012.1303011.07160HepG2TRIM56
TMEM175ENSG00000127419.12143.7650066.902501.103503.718402.69110HepG2TUFM
TMEM175ENSG00000127419.12227.5369070.825601.6837010.498208.82980HepG2UBE2L3
TMEM175ENSG00000127419.12120.0136034.902101.781708.737907.38520HepG2UCHL5
TMEM175ENSG00000127419.12221.03790144.323700.614903.330002.57570HepG2UPF1
TMEM175ENSG00000127419.12106.9297050.880101.071402.655301.58510HepG2XPO5
TMEM175ENSG00000127419.12138.5454058.169301.251904.268403.37420HepG2XRN2
TMEM175ENSG00000127419.12438.77560158.727901.4668024.7010023.47580HepG2ZNF622
TMEM175ENSG00000127419.12328.33430509.50210-0.633906.074905.28540K562AGGF1
TMEM175ENSG00000127419.12342.93660530.15060-0.628505.111104.21160K562AKAP8L
TMEM175ENSG00000127419.12228.49370377.09590-0.722804.119903.43180K562AQR
TMEM175ENSG00000127419.12396.41360556.23790-0.488704.250703.09310K562ATP5C1
TMEM175ENSG00000127419.12222.47240131.149200.762304.424103.19220K562BCLAF1
TMEM175ENSG00000127419.12353.43250501.23470-0.504103.274502.21380K562CELF1
TMEM175ENSG00000127419.12194.02620115.006400.754404.294202.62900K562DDX27
TMEM175ENSG00000127419.12446.29540338.997400.396602.610701.97520K562DDX47
TMEM175ENSG00000127419.12330.60430570.53900-0.787206.104904.72470K562DKC1
TMEM175ENSG00000127419.12290.03140123.327701.233602.576801.34550K562EEF2
TMEM175ENSG00000127419.12210.97950119.112400.824702.394601.54710K562EFTUD2
TMEM175ENSG00000127419.12458.63960238.011800.9462010.934809.65040K562EIF2S2
TMEM175ENSG00000127419.12320.48910195.669000.711802.839601.82130K562EIF3A
TMEM175ENSG00000127419.12195.18660135.403700.527502.384801.33590K562EIF4B
TMEM175ENSG00000127419.1287.19250137.87420-0.661102.156401.39810K562FMR1
TMEM175ENSG00000127419.1216.0291036.93320-1.204201.873501.30400K562G3BP2
TMEM175ENSG00000127419.12321.23290165.748200.954506.877305.97600K562HNRNPC
TMEM175ENSG00000127419.12359.52670562.65530-0.646206.026804.70370K562KIF1C
TMEM175ENSG00000127419.12237.15920147.924300.680903.488401.70840K562LSM11
TMEM175ENSG00000127419.12128.4357079.749000.687402.509601.70730K562MAGOH
TMEM175ENSG00000127419.12409.54180538.57280-0.395102.245801.30980K562MAK16
TMEM175ENSG00000127419.12168.1208079.578001.079006.154504.70190K562MATR3
TMEM175ENSG00000127419.12398.66250630.31150-0.660905.107003.79430K562MBNL1
TMEM175ENSG00000127419.12193.23540441.79980-1.193009.246907.26320K562NAA15
TMEM175ENSG00000127419.12265.37010163.281200.700503.178601.61610K562NUSAP1
TMEM175ENSG00000127419.12568.32100263.404101.109303.367102.45000K562PCBP3
TMEM175ENSG00000127419.12460.04850202.041101.1870013.9568012.22150K562POLR2G
TMEM175ENSG00000127419.12224.92260148.626200.597602.485501.63390K562PSIP1
TMEM175ENSG00000127419.12124.9950077.485600.689802.515301.87810K562PTBP1
TMEM175ENSG00000127419.12346.78410473.05950-0.448002.797001.72240K562PUM1
TMEM175ENSG00000127419.12248.13140525.83130-1.0835010.561109.54650K562PUS1
TMEM175ENSG00000127419.12326.03860512.28760-0.651905.998105.15130K562RBM15
TMEM175ENSG00000127419.12264.66040135.677500.963906.436804.92560K562RCC2
TMEM175ENSG00000127419.12139.9839078.161300.840603.460902.21830K562NELFE
TMEM175ENSG00000127419.12282.81790118.012601.260804.975803.87950K562RPS19
TMEM175ENSG00000127419.12181.2905094.743700.936103.501602.36360K562RPS3
TMEM175ENSG00000127419.12275.82270357.90820-0.375802.053301.34370K562SF3A3
TMEM175ENSG00000127419.12395.30070218.100900.857903.360001.86870K562SFPQ
TMEM175ENSG00000127419.12228.57940128.610800.829604.294102.93620K562SRFBP1
TMEM175ENSG00000127419.12167.3459091.433200.871903.448102.25520K562SRSF4
TMEM175ENSG00000127419.12157.9533071.763401.138104.726503.28520K562SRSF5
TMEM175ENSG00000127419.12167.90380258.20680-0.620903.036801.60150K562SSRP1
TMEM175ENSG00000127419.12181.3415076.870501.238107.387606.17140K562TARDBP
TMEM175ENSG00000127419.12203.0552074.154101.4532010.430508.72040K562TIA1
TMEM175ENSG00000127419.12128.6384072.801900.821202.908301.78260K562TRA2A
TMEM175ENSG00000127419.12485.73610384.530500.337002.292301.63460K562UPF1
TMEM175ENSG00000127419.12288.45370533.07000-0.886004.697802.85110K562UTP18
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMEM175 is not available on ENCORE database.





9 RBPs can affect the splicing of TMEM175 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETMEM175ENSG00000127419.12chr4+9438209439219419039419429442089443060.218000.002390.06099includedK562AKAP8L
SETMEM175ENSG00000127419.12chr4+941496941680926174926328944208944306-0.493000.002990.05988excludedHepG2SRSF1
SETMEM175ENSG00000127419.12chr4+9414969419429262629263289442089442790.552000.000180.06580includedHepG2BCCIP
A3SSTMEM175ENSG00000127419.12chr4+9454339455059454699455059449949450460.725000.000050.00211longerHepG2U2AF2
A3SSTMEM175ENSG00000127419.12chr4+9454339455059454699455059449949450460.321000.000390.04966longerK562HNRNPC
A5SSTMEM175ENSG00000127419.12chr4+9419039424039419039419429442089443060.380000.001320.02363longerK562AQR
MXETMEM175ENSG00000127419.12chr4+945469945505946154946238944994945046946977947142-0.416000.001590.074232includedHepG2XPO5
MXETMEM175ENSG00000127419.12chr4+9454339455059461549462389449949450469469779471420.261000.001650.052161includedHepG2SF3A3
MXETMEM175ENSG00000127419.12chr4+9454339455059461549462389449949450469469779471420.234000.004920.068921includedK562HNRNPC
MXETMEM175ENSG00000127419.12chr4+945469945505946154946238944994945046946977947142-0.291000.005050.091972includedHepG2TIAL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMEM175 is not avaliable on ENCORE database.