SLK

General Information

Gene Name       : SLK
Gene ID             : ENSG00000065613.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SLK)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SLKENSG00000065613.1313.1511.4512.30ENCSR000AEF
HepG2SLKENSG00000065613.137.5113.5610.54ENCSR985KAT
K562SLKENSG00000065613.1315.4117.7616.59ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SLK is not avaliable on ENCORE database.



Proteins bound to RNA
  • SLK RNA is bound by 24 proteins.  







eCLIP assay for SLK is not avaliable on ENCORE database.





24 proteins are bound to SLK RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr10105788464105788560+3'-UTR4.124704.48529K562TIA1
chr10105787373105787415+3'-UTR3.491283.37207K562FAM120A
chr10105785453105785554+3'-UTR,CDS3.223013.39306HepG2GRWD1
chr10105786719105786798+3'-UTR3.946873.46958K562YBX3
chr10105787159105787212+3'-UTR4.447834.57464K562PUM2
chr10105727147105727261+5'-UTR4.350148.20156K562FMR1
chr10105727070105727125+5'-UTR4.545384.79919K562GEMIN5
chr10105727466105727509+5'-UTR,CDS3.671884.20387K562ZNF622
chr10105727058105727119+5'-UTR3.625125.73936K562FMR1
chr10105727057105727270+5'-UTR3.6968514.37721K562FXR2
chr10105726994105727051+5'-UTR4.696148.20930HepG2DDX3X
chr10105726985105727057+5'-UTR3.002403.72338K562FXR2
chr10105726968105727050+5'-UTR3.083464.63906HepG2NCBP2
chr10105727355105727434+5'-UTR5.3511911.78230HepG2DDX3X
chr10105727187105727300+5'-UTR4.0089510.86334HepG2DDX3X
chr10105727478105727600+5'-UTR,CDS3.443305.11891HepG2GRWD1
chr10105727117105727240+5'-UTR3.332225.54182K562DHX30
chr10105727344105727430+5'-UTR5.140227.12197K562FXR2
chr10105727054105727141+5'-UTR5.7196813.24386HepG2DDX3X
chr10105778541105778583+CDS,intron-Proximal3.516625.76403K562UCHL5
chr10105763267105763364+CDS,intron-Proximal4.837773.70131HepG2PRPF8
chr10105762023105762036+CDS4.268424.07272K562AGGF1
chr10105759665105759686+CDS4.359824.34038HepG2BCLAF1
chr10105761240105761283+CDS4.938446.58593HepG2BCLAF1
chr10105762572105762660+CDS3.2173113.23603K562UCHL5
chr10105785332105785365+CDS3.789334.76274K562UCHL5
chr10105762692105762738+CDS3.982146.47664K562ZNF622
chr10105752365105752403+CDS4.229627.09561HepG2BCLAF1
chr10105762686105762753+CDS4.085339.09836HepG2BCLAF1
chr10105762811105762915+CDS6.0994114.96864HepG2BCLAF1
chr10105765671105765704+CDS3.715074.46864HepG2BCLAF1
chr10105763117105763192+CDS4.246449.80976HepG2BCLAF1
chr10105752741105752751+CDS,intron-Proximal3.754074.76554HepG2BCLAF1
chr10105765671105765681+CDS4.366974.42734K562UCHL5
chr10105779522105779662+CDS4.4281010.57284K562UCHL5
chr10105761939105762036+CDS5.1357213.49474HepG2BCLAF1
chr10105765277105765366+CDS,intron-Proximal5.1338413.53654K562SF3B4
chr10105763026105763091+CDS5.8981312.56307HepG2BCLAF1
chr10105765362105765408+CDS4.570613.71570HepG2BCLAF1
chr10105780244105780291+CDS,intron-Proximal3.005944.14020K562BUD13
chr10105762208105762267+CDS4.455748.35706K562UCHL5
chr10105762503105762604+CDS3.517963.81194K562TRA2A
chr10105727588105727651+CDS3.135627.74926K562UCHL5
chr10105779593105779652+CDS3.564425.56491HepG2BCLAF1
chr10105762333105762412+CDS4.3668910.98590HepG2BCLAF1
chr10105785374105785424+CDS3.284956.50677K562UCHL5
chr10105779521105779593+CDS3.181166.91872HepG2BCLAF1
chr10105762761105762813+CDS4.5130610.01989K562UCHL5
chr10105750440105750543+CDS5.0738714.51064HepG2BCLAF1
chr10105762824105762916+CDS4.138943.75533K562TRA2A
chr10105765690105765732+CDS3.725084.49347K562UCHL5
chr10105762258105762299+CDS4.891896.13315HepG2BCLAF1
chr10105762666105762746+CDS3.070553.81025K562AGGF1
chr10105762332105762410+CDS3.889425.33504HepG2HLTF
chr10105762673105762757+CDS3.7557813.36249K562UCHL5
chr10105758886105758928+CDS5.422598.40988HepG2BCLAF1
chr10105762575105762632+CDS3.848536.14048K562ZNF622
chr10105768006105768065+CDS3.149575.26696K562UCHL5
chr10105750456105750516+CDS4.111823.31827HepG2GRWD1
chr10105750435105750524+CDS3.365208.01687K562UCHL5
chr10105763141105763192+CDS3.767147.79455K562UCHL5
chr10105762840105762940+CDS4.6370318.02599K562UCHL5
chr10105762557105762619+CDS5.7765010.24913HepG2BCLAF1
chr10105762490105762545+CDS3.409847.85262K562UCHL5
chr10105762324105762395+CDS3.209124.13927K562HLTF
chr10105761950105762026+CDS3.619903.93112K562RBM15
chr10105727595105727654+CDS,intron-Proximal3.319353.92909K562GRWD1
chr10105761234105761293+CDS3.764008.06634K562UCHL5
chr10105762821105762903+CDS3.397988.71976K562ZNF622
chr10105762992105763079+CDS3.436078.60702K562UCHL5
chr10105785380105785421+CDS3.257164.34695HepG2BCLAF1
chr10105750553105750649+CDS,intron-Proximal4.706364.96013K562PRPF8
chr10105731580105731692+intron-Distal4.216573.80778HepG2QKI
chr10105770428105770478+intron-Distal,intron-Proximal4.899105.31925HepG2QKI
chr10105764495105764584+intron-Distal4.586204.07352K562KHSRP
chr10105770384105770464+intron-Distal4.263894.79321K562RBFOX2
chr10105770464105770544+intron-Distal,intron-Proximal5.230338.57143K562RBFOX2
chr10105770401105770560+intron-Distal,intron-Proximal3.996839.64911K562QKI
chr10105768171105768286+intron-Distal,intron-Proximal4.337874.21433K562PRPF8
chr10105770478105770571+intron-Distal,intron-Proximal4.604129.78867HepG2QKI
chr10105765183105765236+intron-Distal,intron-Proximal3.239363.28806K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SLK is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SLK is not available on ENCORE database.

  • 85 RBPs can affect the levels of SLK.  








The Knockdown/knockout RNA-Seq assay for SLK is not available on ENCORE database.





85 RBPs can affect the gene expression of SLK :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SLKENSG00000065613.91213.979801634.44440-0.429103.201402.18590HepG2ABCF1
SLKENSG00000065613.91649.976101199.774800.459608.567307.61740HepG2ACO1
SLKENSG00000065613.9767.405401037.40630-0.434903.368202.27490HepG2ADAR
SLKENSG00000065613.92160.084501659.806700.380002.525602.01530HepG2AKAP1
SLKENSG00000065613.91008.968201503.02310-0.575008.108906.88710HepG2CALR
SLKENSG00000065613.9914.436901199.50550-0.391505.747804.85240HepG2CKAP4
SLKENSG00000065613.9949.265401282.35080-0.433902.064201.40860HepG2CNOT7
SLKENSG00000065613.9789.895201063.85020-0.429604.904403.55140HepG2YBX3
SLKENSG00000065613.91337.632501539.58350-0.202902.281601.59950HepG2DAZAP1
SLKENSG00000065613.9714.049401065.32830-0.577207.757105.96030HepG2DDX1
SLKENSG00000065613.91298.939001049.216100.307901.993901.32620HepG2DDX55
SLKENSG00000065613.9876.543801044.61230-0.253102.054101.43800HepG2DNAJC21
SLKENSG00000065613.9679.730401035.40090-0.6072011.5135010.28320HepG2DNAJC2
SLKENSG00000065613.91802.561801518.861000.247002.712201.88170HepG2EIF4G1
SLKENSG00000065613.9714.58050917.26050-0.360202.944401.73570HepG2FAM120A
SLKENSG00000065613.92540.055201650.455100.621906.226105.11680HepG2FIP1L1
SLKENSG00000065613.91831.637201441.730200.345202.548901.69620HepG2G3BP2
SLKENSG00000065613.91394.334001915.31840-0.458003.664802.93720HepG2GPKOW
SLKENSG00000065613.9752.019801054.62010-0.487904.627203.82060HepG2HNRNPA1
SLKENSG00000065613.91190.891101435.25730-0.269302.339501.67660HepG2HNRNPF
SLKENSG00000065613.9890.561901402.45420-0.6552015.8439014.34630HepG2HNRNPL
SLKENSG00000065613.9940.019101165.31820-0.310003.384102.71950HepG2HNRNPU
SLKENSG00000065613.91115.971201413.33390-0.340802.940702.19600HepG2IGF2BP1
SLKENSG00000065613.91626.489202556.28080-0.652303.273202.36760HepG2LARP4
SLKENSG00000065613.9988.142201472.69560-0.575704.846504.02980HepG2MATR3
SLKENSG00000065613.91769.124601336.028300.405004.397503.39180HepG2MSI2
SLKENSG00000065613.91662.451101171.979000.504302.486001.65380HepG2PABPC1
SLKENSG00000065613.91404.261201173.110300.259402.614801.86060HepG2PRPF4
SLKENSG00000065613.91556.604301284.414300.277203.167102.58940HepG2PTBP1
SLKENSG00000065613.91205.110301457.30650-0.274102.049801.52480HepG2PUF60
SLKENSG00000065613.91808.859001546.982800.225502.958102.34980HepG2PUM1
SLKENSG00000065613.92124.740101545.860500.458806.275305.27940HepG2PUM2
SLKENSG00000065613.94327.188101296.549001.7387023.6983021.84030HepG2RAVER1
SLKENSG00000065613.91874.840001618.671700.211901.774801.33600HepG2RBM22
SLKENSG00000065613.9680.887102035.06720-1.579607.156104.41580HepG2RBM39
SLKENSG00000065613.91680.398001331.346500.335804.519203.75670HepG2RECQL
SLKENSG00000065613.91387.52120801.161300.792209.559608.22400HepG2RRP9
SLKENSG00000065613.9883.072801037.76480-0.232902.111701.53610HepG2SAFB2
SLKENSG00000065613.93366.801901828.225400.8808037.8001036.50350HepG2SRFBP1
SLKENSG00000065613.92294.409701395.748400.7170020.6082019.56990HepG2SRSF1
SLKENSG00000065613.91785.393601135.538800.6528010.778509.81380HepG2SRSF9
SLKENSG00000065613.92038.132301587.324200.360605.880105.18610HepG2SSB
SLKENSG00000065613.91560.004201044.614900.578505.217604.33490HepG2SUPV3L1
SLKENSG00000065613.91644.626101254.627500.390404.940104.22500HepG2TAF15
SLKENSG00000065613.91245.651601781.44710-0.516105.470204.50200HepG2TARDBP
SLKENSG00000065613.91472.566001152.752800.353103.513202.57550HepG2TIA1
SLKENSG00000065613.9746.448501142.44750-0.6140011.2946010.26920HepG2TRIM56
SLKENSG00000065613.91764.975601274.675200.469402.770701.50330HepG2XRCC5
SLKENSG00000065613.9662.288501028.30470-0.634702.223201.56750HepG2XRN2
SLKENSG00000065613.91364.555101157.739700.237002.539601.89140HepG2ZC3H8
SLKENSG00000065613.91961.419401736.073000.176001.811601.34360HepG2ZNF622
SLKENSG00000065613.92247.951302840.81300-0.337705.417404.66570K562AGGF1
SLKENSG00000065613.92415.439302956.01330-0.291402.407601.79770K562AKAP8L
SLKENSG00000065613.92624.292503412.21680-0.378803.987303.30760K562AQR
SLKENSG00000065613.93561.227704205.01930-0.239703.003901.84840K562CPEB4
SLKENSG00000065613.92491.476002947.82170-0.242602.170901.46780K562CPSF6
SLKENSG00000065613.91287.347301541.52510-0.260002.267901.32990K562CSTF2
SLKENSG00000065613.91582.675401938.25290-0.292402.567501.56450K562DDX3X
SLKENSG00000065613.95145.307104350.938800.241803.578502.84950K562DDX47
SLKENSG00000065613.91455.574401986.11830-0.448403.564701.63320K562DDX51
SLKENSG00000065613.91855.419402754.75260-0.5702012.3202010.95990K562EIF2S2
SLKENSG00000065613.91363.10770944.484200.529202.769001.76520K562EIF3A
SLKENSG00000065613.92596.493901969.352000.398702.975301.89950K562EIF3D
SLKENSG00000065613.92303.895301946.931700.242802.502801.74570K562EIF3G
SLKENSG00000065613.91656.050902025.01570-0.290202.309801.55780K562EIF4A3
SLKENSG00000065613.92343.615403284.33660-0.486905.959704.68070K562FIP1L1
SLKENSG00000065613.93559.126202297.061100.631605.695004.59760K562G3BP2
SLKENSG00000065613.92062.958602814.44040-0.448105.395004.29230K562GPKOW
SLKENSG00000065613.92368.019403671.17710-0.6326011.020709.48450K562GRSF1
SLKENSG00000065613.91181.089001734.15990-0.554106.966705.07640K562HNRNPF
SLKENSG00000065613.93167.825403932.12600-0.311803.233102.08120K562HNRNPL
SLKENSG00000065613.91944.647302701.35100-0.474204.243603.07440K562HNRNPM
SLKENSG00000065613.93289.066004452.95120-0.437105.041403.98020K562HSPD1
SLKENSG00000065613.92088.931902651.18810-0.343903.244801.92680K562IGF2BP3
SLKENSG00000065613.91856.823202403.19140-0.372102.163501.34930K562KRR1
SLKENSG00000065613.92184.771502739.86290-0.326603.171202.26880K562MAGOH
SLKENSG00000065613.91975.742602734.43740-0.468806.225304.76180K562MATR3
SLKENSG00000065613.91968.192302747.20960-0.481106.229204.88840K562METAP2
SLKENSG00000065613.92498.977702977.41770-0.252703.706502.78110K562MTPAP
SLKENSG00000065613.91479.837901911.93890-0.369602.712601.31190K562NUSAP1
SLKENSG00000065613.91386.068401896.01070-0.452004.154302.35250K562PHF6
SLKENSG00000065613.92414.763703728.28120-0.626609.149407.42880K562PPIG
SLKENSG00000065613.91085.692601741.31170-0.681609.257907.39970K562PSIP1
SLKENSG00000065613.96702.693505442.202600.300504.159502.83340K562PUM1
SLKENSG00000065613.93573.487902931.421600.285602.145401.65510K562PUS1
SLKENSG00000065613.91939.520902552.90510-0.396403.956102.93540K562RBM22
SLKENSG00000065613.92255.920903640.18380-0.690303.072901.42990K562RBM39
SLKENSG00000065613.91202.341701588.43690-0.401804.155402.93810K562RCC2
SLKENSG00000065613.91539.932402706.34240-0.813503.481502.08950K562SF1
SLKENSG00000065613.91599.049302389.54480-0.579506.160404.84780K562SF3B4
SLKENSG00000065613.92007.830303300.03700-0.716803.270401.80850K562SFPQ
SLKENSG00000065613.91094.356601505.82520-0.460504.447603.06040K562SRFBP1
SLKENSG00000065613.91654.491502641.12960-0.674806.250005.14880K562TARDBP
SLKENSG00000065613.91947.775102547.61230-0.387304.588503.49450K562TIA1
SLKENSG00000065613.91204.658301779.03140-0.562506.550204.95020K562TRIM56
SLKENSG00000065613.91728.653902227.72920-0.365902.543401.50130K562U2AF1
SLKENSG00000065613.91785.522802300.38950-0.365504.258803.26660K562U2AF2
SLKENSG00000065613.93897.425003121.166900.320306.668105.40760K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SLK is not available on ENCORE database.





18 RBPs can affect the splicing of SLK :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESLKENSG00000065613.9chr10+105770573105770666105767934105768114105777917105778047-0.179000.000000.00001excludedHepG2U2AF1
SESLKENSG00000065613.9chr10+105765669105765793105761201105761330105767934105768114-0.055000.001650.04652excludedK562AKAP8L
SESLKENSG00000065613.9chr10+1057705731057706661057679341057681141057779171057780470.355000.000000.00000includedHepG2TBRG4
SESLKENSG00000065613.9chr10+105770573105770666105767934105768114105777917105778047-0.067000.010140.09239excludedHepG2U2AF2
SESLKENSG00000065613.9chr10+105778541105778666105777917105778047105779491105779680-0.058000.000670.00866excludedK562AQR
SESLKENSG00000065613.9chr10+1057705731057706661057679341057681141057779171057780470.437000.000000.00000includedHepG2DDX3X
SESLKENSG00000065613.9chr10+1057619291057632851057612011057613301057653181057654490.172000.000460.04083includedK562SUPV3L1
SESLKENSG00000065613.9chr10+105778541105778666105777917105778047105779491105779680-0.060000.000040.00112excludedK562PUS1
SESLKENSG00000065613.9chr10+105765669105765793105761201105761330105767934105768114-0.109000.000000.00001excludedK562PUS1
SESLKENSG00000065613.9chr10+1057705731057706661057679341057681141057779171057780470.246000.000010.00152includedHepG2NCBP2
SESLKENSG00000065613.9chr10+105770573105770666105767934105768114105777917105778047-0.084000.000510.02982excludedHepG2PTBP1
SESLKENSG00000065613.9chr10+1057705731057706661057679341057681141057779171057780470.391000.000000.00000includedHepG2FTO
SESLKENSG00000065613.9chr10+105778541105778666105777917105778047105779491105779680-0.058000.005390.08606excludedK562U2AF1
SESLKENSG00000065613.9chr10+1057705731057706661057679341057681141057779171057780470.074000.000100.02138includedK562HNRNPM
SESLKENSG00000065613.9chr10+1057705731057706661057679341057681141057779171057780470.314000.000000.00014includedHepG2HNRNPUL1
SESLKENSG00000065613.9chr10+1057705731057706661057679341057681141057779171057780470.163000.000110.04723includedHepG2XPO5
SESLKENSG00000065613.9chr10+1057705731057706661057679341057681141057779171057780470.280000.000000.00008includedHepG2SUPV3L1
SESLKENSG00000065613.9chr10+105765669105765793105761201105761330105767934105768114-0.056000.000500.02014excludedK562UTP18
SESLKENSG00000065613.9chr10+1057619291057632851057612011057613301057653181057654490.165000.002410.04056includedK562U2AF2
SESLKENSG00000065613.9chr10+105758656105758729105752741105752891105758876105759071-0.066000.001810.03229excludedK562U2AF2
SESLKENSG00000065613.9chr10+1057619291057632851057612011057613301057653181057654490.115000.000800.03175includedK562HNRNPU
SESLKENSG00000065613.9chr10+105765669105765793105761201105761330105767934105768114-0.078000.000030.00149excludedK562RBM15
SESLKENSG00000065613.9chr10+105778541105778666105777917105778047105779491105779680-0.064000.000020.00127excludedK562AGGF1
SESLKENSG00000065613.9chr10+105761929105763285105761201105761330105765318105765449-0.149000.000120.00517excludedK562AGGF1
A3SSSLKENSG00000065613.9chr10+1057527141057528911057527411057528911057523551057524040.087000.017730.08603longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SLK is not avaliable on ENCORE database.