SETD1B

General Information

Gene Name       : SETD1B
Gene ID             : ENSG00000139718.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: SETD1B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SETD1BENSG00000139718.101.102.421.76ENCSR000AEF
HepG2SETD1BENSG00000139718.106.582.604.59ENCSR985KAT
K562SETD1BENSG00000139718.107.634.085.86ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SETD1B is not avaliable on ENCORE database.



Proteins bound to RNA
  • SETD1B RNA is bound by 24 proteins.  







eCLIP assay for SETD1B is not avaliable on ENCORE database.





24 proteins are bound to SETD1B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12122269699122269748+3'-UTR5.6714515.74283K562PUM2
chr12122269597122269670+3'-UTR3.836585.48036K562PUM1
chr12122268408122268500+3'-UTR3.497384.12870K562PTBP1
chr12122268418122268499+3'-UTR3.148634.55951HepG2PCBP2
chr12122269817122269862+3'-UTR4.3441812.04150K562TIA1
chr12122269549122269570+3'-UTR5.693768.15847K562PUM2
chr12122269813122269866+3'-UTR4.6292817.41829K562PUM2
chr12122269416122269465+3'-UTR5.1726714.69153K562PUM2
chr12122270425122270476+3'-UTR7.8942329.20897K562PUM2
chr12122270481122270528+3'-UTR7.2637211.45561K562PUM2
chr12122269593122269648+3'-UTR6.7980521.32157K562PUM2
chr12122242097122242205+5'-UTR,intron-Proximal3.938246.03429HepG2CSTF2T
chr12122247883122247944+CDS5.002796.54449K562RBM15
chr12122260703122260823+CDS4.621239.20373HepG2DDX59
chr12122260877122260975+CDS5.864129.83211HepG2PCBP2
chr12122247839122247921+CDS3.981573.65594HepG2EIF3H
chr12122248127122248154+CDS3.508199.03323K562RBM15
chr12122260727122260792+CDS4.711215.17013K562RBM15
chr12122242742122242815+CDS4.688315.50697K562UCHL5
chr12122252285122252351+CDS4.362665.47084HepG2DDX59
chr12122260934122261021+CDS3.343573.34034HepG2HLTF
chr12122265546122265601+CDS,intron-Proximal5.243035.68502HepG2PRPF8
chr12122252523122252631+CDS4.272628.37444K562RBM15
chr12122247983122248032+CDS3.830223.52163HepG2IGF2BP1
chr12122242720122242818+CDS,intron-Proximal3.098703.80349K562ZNF622
chr12122247983122248029+CDS4.418508.71170K562RBM15
chr12122247848122247883+CDS3.144083.34231K562RBM15
chr12122260715122260838+CDS4.401794.57222K562HNRNPK
chr12122248109122248117+CDS4.212118.38961K562RBM15
chr12122243062122243109+CDS3.522403.90826K562ZNF622
chr12122248038122248078+CDS3.477654.22460K562RBM15
chr12122260990122261072+CDS4.956478.06993HepG2DDX59
chr12122252270122252454+CDS4.042876.90820K562HNRNPK
chr12122257444122257510+CDS4.804753.81516HepG2EIF3H
chr12122260886122260942+CDS4.390553.94601K562PCBP1
chr12122255151122255191+CDS4.062483.49332HepG2PPIG
chr12122252275122252355+CDS4.455803.39700HepG2PCBP2
chr12122261152122261207+CDS4.525086.92189HepG2PCBP2
chr12122248612122248668+CDS3.620816.49817K562RBM15
chr12122257510122257573+CDS3.456763.15756HepG2EIF3H
chr12122260722122260830+CDS4.426765.43223K562PCBP1
chr12122261072122261178+CDS4.949409.58366HepG2DDX59
chr12122248668122248725+CDS3.682673.93112K562RBM15
chr12122261110122261213+CDS3.012193.00437HepG2HNRNPK
chr12122263264122263315+CDS,intron-Proximal4.186183.95187HepG2AQR
chr12122260547122260622+CDS5.297087.93248K562RBM15
chr12122252255122252368+CDS3.914235.09665HepG2HNRNPK
chr12122261075122261147+CDS4.174166.37184K562RBM15
chr12122248682122248742+CDS,intron-Proximal4.267184.38106HepG2PPIG
chr12122243746122243888+CDS3.526885.97823HepG2BCLAF1
chr12122252292122252468+CDS3.627186.52856K562FXR2
chr12122248488122248529+CDS4.080966.37184K562RBM15
chr12122248568122248633+CDS4.042723.56076K562BUD13
chr12122260878122261023+CDS3.707335.82160HepG2HNRNPK
chr12122250635122250730+intron-Distal4.532495.29390K562TARDBP
chr12122266987122267067+intron-Distal4.213813.48173K562GTF2F1
chr12122255873122255949+intron-Distal,intron-Proximal4.252913.12843K562PRPF8
chr12122242562122242615+intron-Proximal4.115755.68247K562SF3B4
chr12122242555122242622+intron-Proximal3.238304.01547K562TIA1
chr12122242565122242606+intron-Proximal4.160703.49003K562PRPF8
chr12122242569122242615+intron-Proximal3.511034.05505HepG2SF3B4
chr12122252842122252903+intron-Proximal4.895794.65563K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SETD1B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SETD1B is not available on ENCORE database.

  • 110 RBPs can affect the levels of SETD1B.  








The Knockdown/knockout RNA-Seq assay for SETD1B is not available on ENCORE database.





110 RBPs can affect the gene expression of SETD1B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SETD1BENSG00000139718.6823.94680631.473500.383704.153703.43710HepG2ACO1
SETD1BENSG00000139718.6837.22230634.424400.400104.154503.22810HepG2AKAP8L
SETD1BENSG00000139718.6945.83400766.742100.302701.958801.36370HepG2AUH
SETD1BENSG00000139718.61572.48970942.954500.7377010.218409.16310HepG2BOP1
SETD1BENSG00000139718.6341.81770541.89570-0.664805.587704.54050HepG2CALR
SETD1BENSG00000139718.6873.07460631.317000.467606.284105.35450HepG2CKAP4
SETD1BENSG00000139718.61093.15670801.294600.448004.036902.71020HepG2CPSF7
SETD1BENSG00000139718.61001.225501403.00110-0.486704.933103.23090HepG2DDX47
SETD1BENSG00000139718.6456.77220280.012500.705908.120107.07560HepG2DNAJC2
SETD1BENSG00000139718.6672.24750408.567300.718304.955303.75430HepG2EEF2
SETD1BENSG00000139718.6549.82550368.279800.578102.579202.00650HepG2EIF2S1
SETD1BENSG00000139718.61030.75220738.121900.481704.711503.20790HepG2EIF2S2
SETD1BENSG00000139718.6779.12280396.375900.974907.911206.77800HepG2EIF4B
SETD1BENSG00000139718.6553.84840440.885600.329002.101601.35590HepG2EIF4G1
SETD1BENSG00000139718.6410.59750296.484100.469702.941801.73380HepG2FAM120A
SETD1BENSG00000139718.6629.16430410.879100.614602.972102.25390HepG2FXR1
SETD1BENSG00000139718.6825.31130380.960601.1152013.3242011.92440HepG2G3BP1
SETD1BENSG00000139718.6639.18110404.686800.659303.331202.34610HepG2G3BP2
SETD1BENSG00000139718.6750.47580602.864800.315902.782401.80300HepG2HDGF
SETD1BENSG00000139718.6716.75390393.256700.865905.623603.59460HepG2HNRNPA0
SETD1BENSG00000139718.6476.19170317.229700.585903.904703.09160HepG2HNRNPC
SETD1BENSG00000139718.6839.86720647.513500.375202.175401.53420HepG2HNRNPF
SETD1BENSG00000139718.6723.13080386.200700.904806.800805.74300HepG2HNRNPK
SETD1BENSG00000139718.6522.15780315.131800.728408.744907.71320HepG2HNRNPU
SETD1BENSG00000139718.6783.72530637.613000.297601.968301.34940HepG2IGF2BP1
SETD1BENSG00000139718.61562.87940872.925300.840208.533307.06850HepG2LARP4
SETD1BENSG00000139718.6597.85270411.024100.540502.241701.64930HepG2MAGOH
SETD1BENSG00000139718.6872.67970413.265801.0783011.147809.94360HepG2MATR3
SETD1BENSG00000139718.6974.78300422.952801.2045014.7324013.34880HepG2NCBP2
SETD1BENSG00000139718.6607.93520443.170100.456003.610102.73960HepG2NOL12
SETD1BENSG00000139718.6718.70700374.259100.941306.848504.59790HepG2NOLC1
SETD1BENSG00000139718.6823.76270346.448201.249503.165901.99270HepG2NONO
SETD1BENSG00000139718.61183.54040424.627901.4787012.5871010.65990HepG2PABPC1
SETD1BENSG00000139718.6543.22840376.447600.529002.271701.61240HepG2PABPC4
SETD1BENSG00000139718.6452.10860311.917200.535404.450303.40640HepG2PARN
SETD1BENSG00000139718.6737.51820389.075600.922508.327707.36760HepG2PCBP1
SETD1BENSG00000139718.6410.07530274.245000.580304.107902.60100HepG2PKM
SETD1BENSG00000139718.6505.45610281.071100.8466010.088408.72880HepG2PPIL4
SETD1BENSG00000139718.6755.03070395.950700.9311016.0745014.96570HepG2PTBP1
SETD1BENSG00000139718.6582.25990423.033100.460803.120302.49330HepG2PUF60
SETD1BENSG00000139718.6815.28320449.054800.8603013.6263012.52090HepG2PUM1
SETD1BENSG00000139718.6831.78780448.735200.890309.979308.74800HepG2PUM2
SETD1BENSG00000139718.6773.16620643.193900.265402.180201.61800HepG2PUS1
SETD1BENSG00000139718.6564.45180428.714200.396702.627402.01590HepG2QKI
SETD1BENSG00000139718.6533.84590326.215800.710503.304102.53660HepG2RAVER1
SETD1BENSG00000139718.6668.95780389.127300.781609.031807.86910HepG2RBM25
SETD1BENSG00000139718.6677.13800386.793900.807806.573005.03890HepG2RBM27
SETD1BENSG00000139718.6717.08420440.612100.702508.548507.69380HepG2NELFE
SETD1BENSG00000139718.6560.17520410.448200.448602.941702.30810HepG2RECQL
SETD1BENSG00000139718.6511.58010697.57540-0.447403.243802.51330HepG2RPLP0
SETD1BENSG00000139718.6577.09100322.726700.838406.067405.19770HepG2RPS19
SETD1BENSG00000139718.6496.05990356.689700.475702.270801.54070HepG2RPS2
SETD1BENSG00000139718.6453.24920280.634400.691507.195406.22670HepG2SAFB2
SETD1BENSG00000139718.6857.23070412.143101.0564021.2171019.83430HepG2SF3B4
SETD1BENSG00000139718.6635.81540405.595100.648508.262007.14840HepG2SLBP
SETD1BENSG00000139718.6492.72740327.259700.590306.016905.12520HepG2SMN1
SETD1BENSG00000139718.6834.23820427.465400.964603.046601.65420HepG2SNRNP200
SETD1BENSG00000139718.61474.139401031.201700.515402.854902.06130HepG2SNRNP70
SETD1BENSG00000139718.61010.29660831.074000.281602.354001.87990HepG2SRFBP1
SETD1BENSG00000139718.61341.85000997.360200.427902.666401.68580HepG2SRSF3
SETD1BENSG00000139718.6938.62520417.667401.1681027.4457025.75900HepG2SRSF5
SETD1BENSG00000139718.6769.50590475.016800.6959010.444609.36710HepG2SUCLG1
SETD1BENSG00000139718.6417.18450306.181300.446202.803002.30010HepG2TIAL1
SETD1BENSG00000139718.6563.35400308.948500.8666012.1331011.07400HepG2TRIM56
SETD1BENSG00000139718.6797.03540413.263400.947504.514103.36490HepG2TUFM
SETD1BENSG00000139718.61969.38140840.492301.2283024.9832023.03640HepG2U2AF1
SETD1BENSG00000139718.61618.89470496.966101.703707.854206.10910HepG2U2AF2
SETD1BENSG00000139718.6369.44210221.753700.736304.629403.64290HepG2UCHL5
SETD1BENSG00000139718.61281.480601060.517900.272902.965402.24630HepG2UPF1
SETD1BENSG00000139718.61491.686101023.888900.542809.422208.42400HepG2UTP3
SETD1BENSG00000139718.6828.032801344.96180-0.6998013.7010012.54080K562AGGF1
SETD1BENSG00000139718.61085.288501399.49140-0.366803.046702.36060K562AKAP8L
SETD1BENSG00000139718.62323.745001188.737500.9669018.1600016.82320K562AQR
SETD1BENSG00000139718.61226.972001468.39910-0.259102.156501.35710K562ATP5C1
SETD1BENSG00000139718.6801.54450596.016000.427303.336301.86840K562BCCIP
SETD1BENSG00000139718.61257.90600732.728000.779605.516503.90510K562CCAR1
SETD1BENSG00000139718.61619.824801968.75340-0.281402.262801.38040K562CELF1
SETD1BENSG00000139718.6406.86900556.05360-0.450703.720401.61220K562DDX24
SETD1BENSG00000139718.62353.155101810.005300.378506.084505.17070K562DDX47
SETD1BENSG00000139718.61295.47600820.385700.659004.756502.91370K562DHX30
SETD1BENSG00000139718.61162.736901505.96720-0.373204.603903.43190K562DKC1
SETD1BENSG00000139718.6868.45800569.650200.608305.455704.14650K562EFTUD2
SETD1BENSG00000139718.61412.321401189.711500.247402.292201.62850K562EIF2S2
SETD1BENSG00000139718.61432.01020745.271600.942104.953603.56500K562EIF3A
SETD1BENSG00000139718.6851.95610609.829500.482303.056601.96810K562EIF3D
SETD1BENSG00000139718.6583.22680374.251900.639906.748405.51810K562EIF3G
SETD1BENSG00000139718.6737.35230476.751000.629005.193702.52760K562EIF3H
SETD1BENSG00000139718.62487.717801601.378700.6354012.1991010.30210K562EIF4G2
SETD1BENSG00000139718.61079.92620570.163600.9214018.3022016.85480K562FXR1
SETD1BENSG00000139718.61213.03550625.706700.9550015.8981014.54770K562HNRNPC
SETD1BENSG00000139718.6840.44610558.924800.588405.637003.92600K562HNRNPF
SETD1BENSG00000139718.61127.431401748.62110-0.633202.809202.00800K562HSPD1
SETD1BENSG00000139718.6530.17800387.098500.453702.281401.37430K562IGF2BP2
SETD1BENSG00000139718.6992.535901485.21810-0.581503.381102.45860K562KIF1C
SETD1BENSG00000139718.6745.88780558.319200.417803.034201.41910K562LSM11
SETD1BENSG00000139718.6674.74730406.694900.730308.070806.59960K562MAGOH
SETD1BENSG00000139718.6712.69580405.850000.8122010.257308.37720K562MATR3
SETD1BENSG00000139718.6748.383901166.21540-0.640004.791103.52720K562NAA15
SETD1BENSG00000139718.6727.96010361.834001.0084010.937608.91280K562PCBP2
SETD1BENSG00000139718.62159.569901365.011600.661702.053701.33770K562PCBP3
SETD1BENSG00000139718.62083.419801645.450700.340403.389001.80420K562PNPT1
SETD1BENSG00000139718.61599.216001046.969000.611008.940007.53180K562POLR2G
SETD1BENSG00000139718.61051.259001463.81200-0.477602.135001.41880K562PPIG
SETD1BENSG00000139718.6932.64720554.337600.750507.691506.43370K562PRPF8
SETD1BENSG00000139718.6750.39950561.058300.419402.180301.38590K562PSIP1
SETD1BENSG00000139718.6839.56870395.139301.087209.654508.46820K562PTBP1
SETD1BENSG00000139718.62764.050001747.259300.661607.623306.26350K562PUF60
SETD1BENSG00000139718.6884.482401387.92780-0.650006.829206.02040K562PUS1
SETD1BENSG00000139718.61060.576701352.31300-0.350603.559202.90050K562RBM15
SETD1BENSG00000139718.6798.69700378.820201.0760015.8328013.62520K562RBM22
SETD1BENSG00000139718.6611.84040369.331900.728106.363504.07690K562RBM34
SETD1BENSG00000139718.6680.05440512.118000.409102.890901.87700K562RCC2
SETD1BENSG00000139718.6596.72010398.664300.581804.475503.04910K562NELFE
SETD1BENSG00000139718.6788.68760438.152400.847908.191206.35980K562RPS3
SETD1BENSG00000139718.61555.17940933.004900.737004.400303.02360K562SAFB
SETD1BENSG00000139718.6419.45230205.737901.0276011.536909.71520K562SF3B4
SETD1BENSG00000139718.6820.62320485.450900.757306.439304.69480K562SRFBP1
SETD1BENSG00000139718.6715.37830387.382900.8848011.128909.72380K562SRSF1
SETD1BENSG00000139718.61034.99700422.886401.2912023.8097020.56290K562SRSF4
SETD1BENSG00000139718.6549.95830365.890200.587804.643203.21920K562SRSF5
SETD1BENSG00000139718.61203.35490392.025201.6179031.3302028.38000K562TARDBP
SETD1BENSG00000139718.6753.22620378.160900.9940014.5591012.56470K562TIA1
SETD1BENSG00000139718.6557.40960371.163000.586604.447403.00550K562TRA2A
SETD1BENSG00000139718.6813.81380573.524400.504704.193802.97770K562TRIM56
SETD1BENSG00000139718.61457.08050992.391100.554004.865702.44740K562TRNAU1AP
SETD1BENSG00000139718.6332.00690198.082800.745005.649504.50150K562U2AF2
SETD1BENSG00000139718.61987.352701568.040200.341805.541404.38630K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SETD1B is not available on ENCORE database.






No RBPs affect the alternative splcing events of SETD1B on ENCORE database.





The Knockdown/knockout RNA-Seq assay for SETD1B is not avaliable on ENCORE database.