SEC22B

General Information

Gene Name       : SEC22B
Gene ID             : ENSG00000265808.3
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SEC22B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SEC22BENSG00000265808.321.4520.4320.94ENCSR000AEF
HepG2SEC22BENSG00000265808.311.6919.9515.82ENCSR985KAT
K562SEC22BENSG00000265808.315.1315.3315.23ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SEC22B is not avaliable on ENCORE database.



Proteins bound to RNA
  • SEC22B RNA is bound by 15 proteins.  







eCLIP assay for SEC22B is not avaliable on ENCORE database.





15 proteins are bound to SEC22B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1145096695145096748+intron-Distal,intron-Proximal3.472925.17815K562RBM15
chr1145096762145096802+intron-Distal3.867624.21358HepG2U2AF2
chr1145096758145096833+intron-Distal4.291353.25843K562SRSF1
chr1145096768145096803+intron-Distal3.193853.04831K562RBM15
chr1145106444145106509+intron-Distal3.132323.68431K562TARDBP
chr1145101423145101505+intron-Distal3.9018214.05428K562RBFOX2
chr1145114877145114959+intron-Distal3.636744.52210K562KHSRP
chr1145108207145108290+intron-Distal3.355113.85034K562ILF3
chr1145097207145097252+intron-Distal4.341705.60471HepG2U2AF2
chr1145097111145097161+intron-Distal3.129613.05068HepG2U2AF2
chr1145096909145096996+intron-Distal3.6306610.10979HepG2U2AF2
chr1145096827145096901+intron-Distal3.834176.33374K562TIA1
chr1145096751145096809+intron-Distal3.728564.45024K562U2AF2
chr1145104116145104277+intron-Distal,intron-Proximal3.771139.89511K562KHSRP
chr1145096558145096624+intron-Proximal3.624269.72918K562UCHL5
chr1145112515145112535+intron-Proximal3.088438.34591K562AQR
chr1145096524145096624+intron-Proximal3.2710314.24707HepG2GRWD1
chr1145115707145115760+intron-Proximal4.9141732.68152K562GPKOW
chr1145112544145112569+intron-Proximal3.4466210.21503K562AQR
chr1145115734145115748+intron-Proximal3.389774.02291HepG2GRWD1
chr1145112494145112556+intron-Proximal4.525968.44604HepG2PRPF8
chr1145103897145103949+intron-Proximal4.042726.60968K562BUD13
chr1145115716145115754+intron-Proximal3.8148813.49949K562BUD13
chr1145103980145104041+intron-Proximal4.6745819.60859HepG2PRPF8
chr1145115673145115709+intron-Proximal4.882428.05832K562SF3B4
chr1145115734145115781+intron-Proximal3.402904.58459K562GRWD1
chr1145115709145115762+intron-Proximal5.1803918.60679K562SF3B4
chr1145096625145096679+intron-Proximal3.908275.36986K562RBM15
chr1145115720145115790+intron-Proximal4.210984.47532K562U2AF2
chr1145096612145096662+intron-Proximal3.063107.66017HepG2PRPF8
chr1145096552145096625+intron-Proximal3.316418.86652K562RBM15
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SEC22B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SEC22B is not available on ENCORE database.

  • 86 RBPs can affect the levels of SEC22B.  








The Knockdown/knockout RNA-Seq assay for SEC22B is not available on ENCORE database.





86 RBPs can affect the gene expression of SEC22B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SEC22BENSG00000223380.3742.968901021.71720-0.459606.458405.60910HepG2ACO1
SEC22BENSG00000223380.3699.48960936.44600-0.420902.448801.46660HepG2AKAP8
SEC22BENSG00000223380.31045.658101371.88240-0.391702.803702.01510HepG2ASCC1
SEC22BENSG00000223380.31471.924301148.976500.357303.122801.62710HepG2ATP5C1
SEC22BENSG00000223380.3914.836401561.69170-0.7715018.1233016.65350HepG2AUH
SEC22BENSG00000223380.31292.30590883.664700.548304.841203.68160HepG2BCLAF1
SEC22BENSG00000223380.31025.269001376.06610-0.424503.715003.03230HepG2BOP1
SEC22BENSG00000223380.31738.502701303.378300.415503.476802.61640HepG2CIRBP
SEC22BENSG00000223380.31130.83970810.599700.480202.381601.67540HepG2CNOT7
SEC22BENSG00000223380.31590.226901263.335900.331902.556601.89130HepG2CPSF6
SEC22BENSG00000223380.31614.075001318.107000.292103.071002.40070HepG2CELF1
SEC22BENSG00000223380.3507.63220944.96510-0.8965021.0128019.22870HepG2DDX19B
SEC22BENSG00000223380.31169.44490893.382400.388404.293502.87400HepG2DDX1
SEC22BENSG00000223380.31468.26710815.876700.8476013.1819011.83960HepG2DDX21
SEC22BENSG00000223380.31155.03310884.831500.384403.052301.69460HepG2DDX47
SEC22BENSG00000223380.31415.624601060.395500.416703.485602.35950HepG2DDX5
SEC22BENSG00000223380.3929.315701364.29790-0.553904.346003.58640HepG2DDX6
SEC22BENSG00000223380.3573.74480876.02390-0.610608.141806.98800HepG2DNAJC21
SEC22BENSG00000223380.31267.91610909.684500.478903.988602.90190HepG2EEF2
SEC22BENSG00000223380.3960.845201449.50840-0.593205.083004.21890HepG2EIF4A3
SEC22BENSG00000223380.3392.950701411.23560-1.8445029.3577027.31220HepG2EIF4B
SEC22BENSG00000223380.3654.945201398.26190-1.0942031.7417029.58000HepG2EIF4G1
SEC22BENSG00000223380.31503.711901793.09810-0.253902.774902.17330HepG2ETF1
SEC22BENSG00000223380.31041.88370777.379000.422403.636202.34960HepG2FASTKD2
SEC22BENSG00000223380.3803.538001285.46590-0.677905.827004.75070HepG2FIP1L1
SEC22BENSG00000223380.31146.195101462.39140-0.351502.416901.76840HepG2FXR1
SEC22BENSG00000223380.3967.994901356.63600-0.487003.757902.98620HepG2G3BP1
SEC22BENSG00000223380.3430.20650685.03100-0.671104.376602.62020HepG2HNRNPA0
SEC22BENSG00000223380.3772.11690983.73090-0.349402.454301.79810HepG2HNRNPC
SEC22BENSG00000223380.31115.571501373.59180-0.300202.005201.40380HepG2HNRNPK
SEC22BENSG00000223380.31088.06150886.997500.294702.230501.37600HepG2HNRNPM
SEC22BENSG00000223380.3624.21570977.22840-0.6467010.814109.68230HepG2HNRNPU
SEC22BENSG00000223380.31376.436401018.958400.433702.602101.39850HepG2KRR1
SEC22BENSG00000223380.31326.262101040.501000.350003.091302.23870HepG2MSI2
SEC22BENSG00000223380.3803.569001405.52790-0.8066015.9918014.24230HepG2NOL12
SEC22BENSG00000223380.31166.17120967.311500.269602.572401.75310HepG2PARN
SEC22BENSG00000223380.31635.832001331.787600.296603.445902.84980HepG2PTBP1
SEC22BENSG00000223380.31693.196401424.175700.249503.093702.47530HepG2PUM1
SEC22BENSG00000223380.3997.821901423.16720-0.512306.854505.81580HepG2PUM2
SEC22BENSG00000223380.31552.779901040.692600.5772012.3526011.21020HepG2PUS1
SEC22BENSG00000223380.3956.197501442.36520-0.593108.992007.96280HepG2QKI
SEC22BENSG00000223380.3485.42560973.30960-1.003607.071305.97180HepG2RAVER1
SEC22BENSG00000223380.3997.019901251.79850-0.328303.032502.13720HepG2RBM15
SEC22BENSG00000223380.31161.557501482.15420-0.351604.313803.66530HepG2NELFE
SEC22BENSG00000223380.31138.664301380.42070-0.277802.936802.30340HepG2RECQL
SEC22BENSG00000223380.3632.28240870.27580-0.460905.855004.97270HepG2SAFB2
SEC22BENSG00000223380.31693.647501270.285500.414902.318401.70120HepG2SF3A3
SEC22BENSG00000223380.31076.264001352.85970-0.330002.377401.72130HepG2SF3B1
SEC22BENSG00000223380.31340.71380992.190900.434202.506301.59840HepG2SMNDC1
SEC22BENSG00000223380.31105.457401692.68400-0.6147014.0169013.12090HepG2SRFBP1
SEC22BENSG00000223380.32222.378001447.274800.6187015.2715014.35200HepG2SRSF1
SEC22BENSG00000223380.3888.588501324.62840-0.5760010.481109.36680HepG2SRSF5
SEC22BENSG00000223380.3834.713501177.43320-0.496307.881807.03510HepG2SRSF9
SEC22BENSG00000223380.31973.588101469.607300.425307.579406.81220HepG2SSB
SEC22BENSG00000223380.3744.108001015.87800-0.449102.800201.51240HepG2SSRP1
SEC22BENSG00000223380.3431.39180707.57650-0.713905.347103.77190HepG2STIP1
SEC22BENSG00000223380.31111.54730868.118800.356503.176402.17470HepG2SUPT6H
SEC22BENSG00000223380.3664.385101300.86090-0.9694021.7355020.37320HepG2TAF15
SEC22BENSG00000223380.3427.28750588.00150-0.460602.757201.99830HepG2UCHL5
SEC22BENSG00000223380.31353.271501126.545500.264402.867202.15760HepG2UPF1
SEC22BENSG00000223380.31827.673901238.989300.5607014.5819013.57060HepG2ZNF622
SEC22BENSG00000223380.32142.871802594.03830-0.275703.768303.12430K562AGGF1
SEC22BENSG00000223380.33415.340002832.122500.270003.342602.33050K562ATP5C1
SEC22BENSG00000223380.3850.247601151.41850-0.437505.158303.26010K562BCCIP
SEC22BENSG00000223380.31989.535001316.433100.595703.075802.15350K562BOP1
SEC22BENSG00000223380.32699.490602054.124200.394103.937702.39980K562CIRBP
SEC22BENSG00000223380.31546.628701894.75960-0.292902.534101.47730K562CPEB4
SEC22BENSG00000223380.31906.059403043.51690-0.675109.868207.19140K562DDX19B
SEC22BENSG00000223380.31651.959601960.18480-0.246802.197001.60570K562DDX47
SEC22BENSG00000223380.32055.706801706.384300.268603.117601.82110K562EIF2S1
SEC22BENSG00000223380.3975.764101228.82290-0.332703.554202.65840K562EIF3G
SEC22BENSG00000223380.31110.087601622.92460-0.547906.172304.95540K562EIF4A3
SEC22BENSG00000223380.3828.029001461.59210-0.8198010.973808.53290K562EIF4B
SEC22BENSG00000223380.31802.220701314.635400.455004.883702.69970K562FASTKD2
SEC22BENSG00000223380.31728.944401086.324700.670305.663903.65450K562FUS
SEC22BENSG00000223380.31019.966701687.78410-0.726609.842508.78320K562FXR1
SEC22BENSG00000223380.32676.023301692.448300.660905.937604.81440K562G3BP2
SEC22BENSG00000223380.32452.424801336.493000.8757016.8364014.81310K562GPKOW
SEC22BENSG00000223380.31160.301801452.99520-0.324502.895401.79640K562HNRNPA1
SEC22BENSG00000223380.31295.37900996.373500.378502.469201.59260K562HNRNPM
SEC22BENSG00000223380.32128.977101642.448900.374203.286802.42240K562HSPD1
SEC22BENSG00000223380.3860.849601175.12010-0.449003.512401.80620K562LIN28B
SEC22BENSG00000223380.31192.819802014.24540-0.7559013.1093011.17190K562MAGOH
SEC22BENSG00000223380.33637.463202616.465600.475202.535101.45670K562MSI2
SEC22BENSG00000223380.31698.752801447.684800.230602.406801.65140K562MTPAP
SEC22BENSG00000223380.3923.234401970.95240-1.094107.448205.55620K562PABPN1
SEC22BENSG00000223380.31017.828201792.23550-0.8163013.5751011.29320K562PCBP2
SEC22BENSG00000223380.31655.860301956.94260-0.241001.972501.39480K562PTBP1
SEC22BENSG00000223380.31520.826001893.80480-0.316403.370101.36950K562QKI
SEC22BENSG00000223380.31273.843101876.64160-0.559006.757005.37620K562RBM22
SEC22BENSG00000223380.31400.331501974.82600-0.496005.009503.49240K562NELFE
SEC22BENSG00000223380.31262.78510960.794200.394202.517401.73980K562RPS19
SEC22BENSG00000223380.31246.859101760.15370-0.497404.517203.19940K562RPS3
SEC22BENSG00000223380.32157.234301587.186200.442607.406906.12220K562SF3A3
SEC22BENSG00000223380.31268.455501918.42190-0.596808.920707.66080K562SRSF1
SEC22BENSG00000223380.31454.129701138.532300.352904.413102.91430K562SRSF7
SEC22BENSG00000223380.31937.563901453.812700.414303.402401.98600K562STAU1
SEC22BENSG00000223380.31556.470801941.64220-0.319002.415401.75180K562TARDBP
SEC22BENSG00000223380.31533.025901872.91370-0.288902.676101.87300K562TIA1
SEC22BENSG00000223380.31995.436701488.158100.423107.110005.04660K562TROVE2
SEC22BENSG00000223380.31354.83060966.571300.487104.383403.07300K562UCHL5
SEC22BENSG00000223380.32139.796501705.536100.327105.061904.12090K562UPF1
SEC22BENSG00000223380.33116.783602555.775400.286202.761101.47330K562WRN
SEC22BENSG00000223380.33085.001602429.102700.344703.479102.49320K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SEC22B is not available on ENCORE database.





9 RBPs can affect the splicing of SEC22B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESEC22BENSG00000223380.3chr1+145103907145104017145096219145096621145109523145109684-0.133000.000000.00000excludedK562SRSF1
SESEC22BENSG00000223380.3chr1+1451039341451040171450965301450966211451095231451096840.080000.000020.00451includedHepG2DDX59
SESEC22BENSG00000223380.3chr1+145103907145104017145096219145096621145109523145109684-0.056000.004260.04078excludedK562AQR
SESEC22BENSG00000223380.3chr1+145103907145104017145096219145096621145109523145109684-0.065000.000920.03683excludedK562FXR1
SESEC22BENSG00000223380.3chr1+145103907145104017145096219145096621145109523145109684-0.093000.000100.02174excludedK562HNRNPM
SESEC22BENSG00000223380.3chr1+1451038661451040171450965301450966211451095231451096840.055000.001360.03532includedK562AGGF1
SESEC22BENSG00000223380.3chr1+145103907145104017145096219145096621145109523145109684-0.063000.000970.04389excludedK562HNRNPK
SESEC22BENSG00000223380.3chr1+1451038931451040171450965301450966211451095231451096840.052000.000310.07869includedHepG2DROSHA
MXESEC22BENSG00000223380.3chr1+1451039071451040171451095231451096841450962191450966211451123721451125190.153000.000910.029881includedHepG2TIAL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SEC22B is not avaliable on ENCORE database.