SDE2

General Information

Gene Name       : SDE2
Gene ID             : ENSG00000143751.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: SDE2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SDE2ENSG00000143751.910.258.299.27ENCSR000AEF
HepG2SDE2ENSG00000143751.97.2713.0110.14ENCSR985KAT
K562SDE2ENSG00000143751.925.7626.8726.32ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SDE2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SDE2 RNA is bound by 19 proteins.  







eCLIP assay for SDE2 is not avaliable on ENCORE database.





19 proteins are bound to SDE2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1226171261226171302-3'-UTR,intron-Distal3.124837.55057K562PUM2
chr1226171157226171226-3'-UTR,intron-Distal3.4350013.24427K562KHSRP
chr1226170597226170626-3'-UTR,intron-Distal3.401584.35650K562KHSRP
chr1226172831226172877-3'-UTR,intron-Distal4.112537.00860K562TIA1
chr1226171901226171942-3'-UTR,intron-Distal4.639626.75148K562TIA1
chr1226170850226170881-3'-UTR,intron-Distal4.752597.01471K562TIA1
chr1226171163226171228-3'-UTR,intron-Distal5.103056.15718HepG2FUBP3
chr1226170913226171001-3'-UTR,intron-Distal4.3987735.35569K562PUM2
chr1226171014226171094-3'-UTR,intron-Distal3.1248910.24861K562KHSRP
chr1226170599226170648-3'-UTR,intron-Distal4.027275.05351HepG2FUBP3
chr1226171094226171157-3'-UTR,intron-Distal3.1451410.13102K562KHSRP
chr1226170966226170997-3'-UTR,intron-Distal3.073895.25167K562TIA1
chr1226171362226171417-3'-UTR,intron-Distal3.071405.98267K562FAM120A
chr1226171169226171225-3'-UTR,intron-Distal3.413858.81237K562UPF1
chr1226170590226170630-3'-UTR,intron-Distal4.139037.39881K562TIA1
chr1226170801226170810-3'-UTR,intron-Distal4.182623.98488K562TIA1
chr1226171598226171645-3'-UTR,intron-Distal4.433879.86765K562TIA1
chr1226171226226171244-3'-UTR,intron-Distal3.444276.67026K562KHSRP
chr1226170648226170714-3'-UTR,intron-Distal4.038283.68079HepG2FUBP3
chr1226171118226171137-3'-UTR,intron-Distal4.362925.23751K562TIA1
chr1226171357226171404-3'-UTR,intron-Distal3.285667.19663K562TIA1
chr1226170712226170768-3'-UTR,intron-Distal5.636477.04933K562CPEB4
chr1226171023226171183-3'-UTR,intron-Distal3.411973.29213HepG2KHSRP
chr1226170541226170591-3'-UTR,intron-Distal4.0124715.23786K562PUM2
chr1226170663226170704-3'-UTR,intron-Distal5.108849.56097K562TIA1
chr1226171629226171656-3'-UTR,intron-Distal3.3955910.10499K562UPF1
chr1226170591226170656-3'-UTR,intron-Distal4.1147820.42490K562PUM2
chr1226170506226170581-3'-UTR,intron-Distal3.924463.97692K562IGF2BP1
chr1226170778226170834-3'-UTR,intron-Distal3.195667.33493K562KHSRP
chr1226171353226171420-3'-UTR,intron-Distal4.553975.35992HepG2UPF1
chr1226171250226171349-3'-UTR,intron-Distal4.9563724.59114K562UPF1
chr1226172726226172796-3'-UTR,intron-Distal3.919765.51967HepG2FUBP3
chr1226172061226172138-3'-UTR,intron-Distal5.0553730.18795K562TIA1
chr1226171607226171629-3'-UTR,intron-Distal3.243169.11693K562UPF1
chr1226172911226172985-3'-UTR,intron-Distal3.8120314.77584K562PUM2
chr1226171349226171423-3'-UTR,intron-Distal5.3849142.16864K562UPF1
chr1226171656226171686-3'-UTR,intron-Distal3.913854.50550K562UPF1
chr1226172761226172774-3'-UTR,intron-Distal4.146094.23094K562TIA1
chr1226186976226187026-5'-UTR,CDS,intron-Distal3.115706.05661K562DDX3X
chr1226175834226176092-CDS,intron-Distal,intron-Proximal3.019033.15057HepG2G3BP1
chr1226175696226175781-CDS,intron-Distal3.592393.06344K562TRA2A
chr1226180599226180700-CDS,intron-Distal3.302118.68700K562ZNF622
chr1226175602226175708-CDS,intron-Distal5.3053215.40437K562ZNF622
chr1226180664226180718-CDS,intron-Distal,intron-Proximal3.556755.28960K562AQR
chr1226175708226175796-CDS,intron-Distal3.236228.14373K562ZNF622
chr1226173068226173207-CDS,intron-Distal4.111823.80193HepG2GRWD1
chr1226173140226173189-CDS,intron-Distal4.039843.65778K562GRWD1
chr1226180664226180756-CDS,intron-Distal,intron-Proximal4.269679.23765K562SF3B4
chr1226186923226186976-CDS,intron-Distal4.047197.62404K562DDX3X
chr1226173059226173115-CDS,intron-Distal3.504104.89070K562UCHL5
chr1226178905226178961-CDS,intron-Distal,intron-Proximal3.870313.86479HepG2PRPF8
chr1226180226226180300-CDS,intron-Distal,intron-Proximal5.1626319.91334K562AQR
chr1226180586226180682-CDS,intron-Distal,intron-Proximal3.076283.17744HepG2GRWD1
chr1226180105226180150-CDS,intron-Distal3.436844.17944K562BUD13
chr1226175592226175711-CDS,intron-Distal,intron-Proximal4.1677719.18150K562UCHL5
chr1226175711226175785-CDS,intron-Distal3.6723611.06562K562UCHL5
chr1226180149226180231-CDS,intron-Distal3.366366.02234K562UCHL5
chr1226180597226180645-CDS,intron-Distal3.844554.06757K562UCHL5
chr1226179024226179079-CDS,intron-Distal,intron-Proximal3.243365.11990K562AQR
chr1226186851226186894-intron-Distal3.636865.83621K562AQR
chr1226173360226173383-intron-Distal4.231484.72162K562KHSRP
chr1226186754226186851-intron-Distal3.587105.35619K562AQR
chr1226178876226178934-intron-Distal,intron-Proximal5.045396.83278K562PRPF8
chr1226178799226178852-intron-Distal,intron-Proximal3.238343.18246K562PRPF8
chr1226185982226186070-intron-Distal3.012784.35941K562KHSRP
chr1226182891226182961-intron-Distal,intron-Proximal5.9244111.56697K562AQR
chr1226180524226180582-intron-Distal,intron-Proximal3.395795.46476K562AQR
chr1226182961226182966-intron-Distal,intron-Proximal5.253897.28294K562AQR
chr1226178809226178915-intron-Distal,intron-Proximal4.142785.35561K562RBM22
chr1226180505226180558-intron-Distal,intron-Proximal4.324934.22101K562PRPF8
chr1226173409226173474-intron-Distal4.3278011.24944K562KHSRP
chr1226180051226180089-intron-Distal,intron-Proximal6.4043217.53326K562AQR
chr1226180089226180099-intron-Distal,intron-Proximal5.2119214.81877K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SDE2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SDE2 is not available on ENCORE database.

  • 93 RBPs can affect the levels of SDE2.  








The Knockdown/knockout RNA-Seq assay for SDE2 is not available on ENCORE database.





93 RBPs can affect the gene expression of SDE2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SDE2ENSG00000143751.9444.30560595.85350-0.423402.256601.40070HepG2ABCF1
SDE2ENSG00000143751.9320.47980469.13250-0.549803.559802.44500HepG2ADAR
SDE2ENSG00000143751.9644.35810870.43470-0.433902.913802.10960HepG2ASCC1
SDE2ENSG00000143751.9722.89720878.82580-0.281802.501301.84280HepG2AUH
SDE2ENSG00000143751.9338.06740549.79190-0.701603.977402.85390HepG2BCCIP
SDE2ENSG00000143751.9681.35500498.259100.451403.226302.58630HepG2BOP1
SDE2ENSG00000143751.9666.79870466.778500.514403.072102.26260HepG2CALR
SDE2ENSG00000143751.9597.71920865.86910-0.534703.688802.98380HepG2DDX6
SDE2ENSG00000143751.9374.85490468.22220-0.320902.245201.64550HepG2DNAJC2
SDE2ENSG00000143751.9379.13030832.13090-1.1341014.2802013.00290HepG2EIF2S1
SDE2ENSG00000143751.91177.937901009.018900.223201.920301.40000HepG2ETF1
SDE2ENSG00000143751.9695.97150928.08430-0.415202.757302.06680HepG2FXR1
SDE2ENSG00000143751.9597.13730860.74180-0.527503.845403.06610HepG2G3BP1
SDE2ENSG00000143751.9237.41960336.81330-0.504502.283901.47730HepG2GEMIN5
SDE2ENSG00000143751.9532.16560654.94850-0.299502.178801.33910HepG2HNRNPA2B1
SDE2ENSG00000143751.9641.78630872.02850-0.442303.240602.48560HepG2HNRNPK
SDE2ENSG00000143751.9609.30550874.85670-0.521904.014503.21470HepG2IGF2BP2
SDE2ENSG00000143751.9653.21230880.08440-0.430102.317801.41250HepG2KHSRP
SDE2ENSG00000143751.9712.47590928.40990-0.381902.335701.73160HepG2MAGOH
SDE2ENSG00000143751.9293.49710504.65490-0.782004.184502.97810HepG2MTPAP
SDE2ENSG00000143751.9527.60300706.67740-0.421603.012502.21730HepG2NOL12
SDE2ENSG00000143751.9746.77270443.954600.750204.242903.12790HepG2PABPC1
SDE2ENSG00000143751.9385.08030521.61760-0.437803.510502.56750HepG2PARN
SDE2ENSG00000143751.9226.63630312.82640-0.465002.461701.30660HepG2PKM
SDE2ENSG00000143751.9323.21760483.55740-0.581205.362604.32060HepG2PRPF4
SDE2ENSG00000143751.9899.71750715.568300.330302.510101.87100HepG2PUM2
SDE2ENSG00000143751.9715.97800506.794500.498402.071301.45340HepG2RAVER1
SDE2ENSG00000143751.9493.87950863.54790-0.8061012.6809011.67880HepG2NELFE
SDE2ENSG00000143751.9569.25260804.29360-0.498705.553604.71800HepG2RECQL
SDE2ENSG00000143751.9257.95140369.43480-0.518202.721401.79060HepG2SERBP1
SDE2ENSG00000143751.9615.29720807.84400-0.392803.726103.05470HepG2SF3B4
SDE2ENSG00000143751.9795.41970646.798000.298302.689501.99560HepG2SLBP
SDE2ENSG00000143751.9422.48400547.27940-0.373403.269902.58010HepG2SMN1
SDE2ENSG00000143751.9842.85190545.029800.628803.624902.72630HepG2SNRNP70
SDE2ENSG00000143751.91167.99540952.530700.294103.276002.74520HepG2SRFBP1
SDE2ENSG00000143751.9822.30640666.037600.304002.567001.95980HepG2SRSF5
SDE2ENSG00000143751.9458.18780757.94250-0.726109.616208.67250HepG2TAF15
SDE2ENSG00000143751.9700.44500514.635900.444602.345101.76230HepG2U2AF1
SDE2ENSG00000143751.9146.62260317.92490-1.116608.426507.10420HepG2UCHL5
SDE2ENSG00000143751.9519.05170665.76980-0.359103.092702.36330HepG2UPF1
SDE2ENSG00000143751.9264.34890492.88910-0.898804.127402.89140HepG2UPF2
SDE2ENSG00000143751.9248.91240529.73430-1.089609.469608.14710HepG2XRN2
SDE2ENSG00000143751.9363.87290477.20910-0.391202.954702.26460HepG2ZC3H8
SDE2ENSG00000143751.92411.617501662.013000.537004.513702.96540K562AARS
SDE2ENSG00000143751.92233.068702689.14020-0.268103.507602.88100K562AGGF1
SDE2ENSG00000143751.92388.185202955.02450-0.307302.606301.65900K562AKAP8
SDE2ENSG00000143751.97200.547603439.775601.0657028.2988026.62440K562AQR
SDE2ENSG00000143751.91534.442501904.72620-0.311904.386103.15970K562BCLAF1
SDE2ENSG00000143751.91320.029601634.98430-0.308702.171301.40490K562BOP1
SDE2ENSG00000143751.9643.61570934.62330-0.538204.615903.17870K562CCAR1
SDE2ENSG00000143751.92667.280803213.61750-0.268802.603501.47100K562CCDC124
SDE2ENSG00000143751.91823.596702304.77020-0.337802.958101.63060K562CIRBP
SDE2ENSG00000143751.92391.581203153.22720-0.398906.844005.07180K562CPEB4
SDE2ENSG00000143751.91217.699901738.48080-0.513706.706005.47720K562CPSF6
SDE2ENSG00000143751.92741.184003262.74450-0.251303.426602.71230K562DDX47
SDE2ENSG00000143751.9777.746301046.28690-0.427903.210301.76900K562DHX30
SDE2ENSG00000143751.92102.910001599.178500.395002.539001.31980K562EEF2
SDE2ENSG00000143751.91291.347001695.94800-0.393205.545603.80050K562EIF2S1
SDE2ENSG00000143751.91561.303202450.83980-0.6505015.0740013.59920K562EIF2S2
SDE2ENSG00000143751.91273.909801654.29720-0.377002.365501.41780K562EIF3D
SDE2ENSG00000143751.93350.854804110.42760-0.294804.539603.34840K562EIF4G2
SDE2ENSG00000143751.91819.408002275.43810-0.322702.781801.93100K562FIP1L1
SDE2ENSG00000143751.91236.949001768.81770-0.516005.349104.15440K562FMR1
SDE2ENSG00000143751.91064.963801499.21290-0.493404.449503.26650K562FTO
SDE2ENSG00000143751.92220.309901677.505700.404306.401605.53690K562FXR1
SDE2ENSG00000143751.91184.706701549.06900-0.386902.816301.38000K562GEMIN5
SDE2ENSG00000143751.91271.429301659.84010-0.384603.522902.63100K562GPKOW
SDE2ENSG00000143751.92088.470103266.12460-0.6451010.587409.08170K562GRSF1
SDE2ENSG00000143751.91116.405601818.90140-0.7042011.1384010.00880K562HNRNPC
SDE2ENSG00000143751.9811.881701624.13790-1.0003019.3854016.48260K562HNRNPF
SDE2ENSG00000143751.92049.287802948.65290-0.524907.600605.76470K562HNRNPL
SDE2ENSG00000143751.92260.403303085.09720-0.448705.041203.98010K562HSPD1
SDE2ENSG00000143751.91667.053402150.50850-0.367402.397101.46200K562IGF2BP2
SDE2ENSG00000143751.91839.109702260.03780-0.297302.593901.77860K562MAGOH
SDE2ENSG00000143751.92761.982102255.443400.292202.816701.88530K562MATR3
SDE2ENSG00000143751.92620.059803326.62110-0.344503.678102.60480K562MBNL1
SDE2ENSG00000143751.91293.321501620.18120-0.325102.808101.92490K562METAP2
SDE2ENSG00000143751.91732.949302521.95500-0.5413013.3734011.75820K562MTPAP
SDE2ENSG00000143751.92046.242502802.09850-0.4535013.7808012.29400K562NSUN2
SDE2ENSG00000143751.91246.496201790.66200-0.522605.302703.08920K562NUSAP1
SDE2ENSG00000143751.91373.567601775.70230-0.370503.237201.67370K562PHF6
SDE2ENSG00000143751.91892.168902632.66570-0.476504.378402.34100K562PKM
SDE2ENSG00000143751.91902.631201562.710800.283802.222601.50440K562POLR2G
SDE2ENSG00000143751.92062.916102582.98350-0.324402.761901.94200K562PPIG
SDE2ENSG00000143751.92088.254201503.560300.473804.732003.75380K562PRPF8
SDE2ENSG00000143751.9900.214101630.79580-0.8572014.0441011.68350K562PSIP1
SDE2ENSG00000143751.93351.577002195.772900.610005.356104.45860K562PTBP1
SDE2ENSG00000143751.95372.832604484.752500.260602.231501.50000K562PUF60
SDE2ENSG00000143751.93476.291304673.87880-0.427107.828506.18740K562PUM2
SDE2ENSG00000143751.91196.052601487.69770-0.314802.791801.79690K562RCC2
SDE2ENSG00000143751.91868.039102764.98590-0.5657012.2885010.67180K562SF3A3
SDE2ENSG00000143751.91929.344401581.720800.286502.773501.91730K562SF3B4
SDE2ENSG00000143751.91736.771702732.47480-0.653802.745901.45390K562SFPQ
SDE2ENSG00000143751.91067.553401410.31750-0.401703.464202.28260K562SRFBP1
SDE2ENSG00000143751.92475.700902832.79040-0.194402.639201.72110K562SRPK2
SDE2ENSG00000143751.91633.875302032.98250-0.315302.503101.51160K562SRSF5
SDE2ENSG00000143751.91142.204201455.72470-0.349902.237401.32940K562SUPV3L1
SDE2ENSG00000143751.91595.640902178.55300-0.449204.356903.46220K562TARDBP
SDE2ENSG00000143751.91729.201802101.46430-0.281302.595001.80520K562TIA1
SDE2ENSG00000143751.91058.014901568.57610-0.568105.486704.12510K562TIAL1
SDE2ENSG00000143751.91289.975901666.19480-0.369203.235302.19380K562TRIM56
SDE2ENSG00000143751.92354.899202747.78720-0.222602.780101.50550K562TROVE2
SDE2ENSG00000143751.91872.970101474.514200.345002.298001.31340K562U2AF1
SDE2ENSG00000143751.9995.713301540.72860-0.629806.917505.22190K562UCHL5
SDE2ENSG00000143751.91975.938602971.12610-0.5885016.9751015.36330K562UPF1
SDE2ENSG00000143751.91571.286602285.57660-0.540603.665502.27320K562UTP3
SDE2ENSG00000143751.92098.139402542.29620-0.277002.542301.69970K562WDR3
SDE2ENSG00000143751.93338.146104075.64010-0.288002.849501.53680K562WRN
SDE2ENSG00000143751.91117.355901568.92920-0.489704.499102.81820K562XRN2
SDE2ENSG00000143751.93054.982403874.95260-0.343003.472802.48740K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SDE2 is not available on ENCORE database.





2 RBPs can affect the splicing of SDE2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESDE2ENSG00000143751.9chr1-226182966226183111226180591226180703226186893226187032-0.066000.000020.00044excludedK562AQR
SESDE2ENSG00000143751.9chr1-226182966226183074226180591226180703226186893226187032-0.061000.000980.01671excludedK562PUS1
A3SSSDE2ENSG00000143751.9chr1-2261800982261803192261800982261802682261805912261807030.198000.000000.00000longerK562AQR
A3SSSDE2ENSG00000143751.9chr1-2261829662261831602261829662261830842261868932261870320.081000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SDE2 is not avaliable on ENCORE database.