RPP21

General Information

Gene Name       : RPP21
Gene ID             : ENSG00000241370.5
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: RPP21)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RPP21ENSG00000241370.51.659.725.69ENCSR000AEF
HepG2RPP21ENSG00000241370.581.4718.6150.04ENCSR985KAT
K562RPP21ENSG00000241370.5169.6756.41113.04ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RPP21 is not avaliable on ENCORE database.



Proteins bound to RNA
  • RPP21 RNA is bound by 8 proteins.  







eCLIP assay for RPP21 is not avaliable on ENCORE database.





8 proteins are bound to RPP21 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr63031448930314607+3'-UTR,CDS,intron-Proximal5.4007010.28790HepG2LARP4
chr63031451430314616+3'-UTR,CDS3.907429.96973K562PABPC4
chr63031294330312990+5'-UTR,CDS,intron-Distal,intron-Proximal4.1773410.05151K562DDX3X
chr63031307430313078+CDS,intron-Proximal3.463184.91258K562YBX3
chr63031299030313005+CDS,intron-Proximal4.0428911.03951K562DDX3X
chr63031313530313171+CDS,intron-Distal,intron-Proximal3.726908.28216K562DDX3X
chr63031308030313135+CDS,intron-Distal,intron-Proximal4.1859624.47255K562DDX3X
chr63031315730313224+CDS,intron-Distal,intron-Proximal3.133946.87008HepG2PRPF8
chr63031325330313300+CDS,intron-Distal,intron-Proximal3.369843.34848HepG2PPIG
chr63031449930314536+CDS3.382604.94406K562YBX3
chr63031313230313141+CDS,intron-Distal3.293126.20049K562YBX3
chr63031329830313350+CDS,intron-Distal3.234285.74118K562YBX3
chr63031419730314266+CDS,intron-Proximal3.153494.05798K562U2AF2
chr63031323130313279+CDS,intron-Distal,intron-Proximal3.232676.41344HepG2PRPF8
chr63031428330314326+CDS3.1496110.46994K562YBX3
chr63031423830314274+CDS4.882608.30668K562YBX3
chr63031419530314243+CDS,intron-Proximal3.040603.41438K562BUD13
chr63031297830313045+CDS,intron-Proximal4.632109.76577HepG2PRPF8
chr63031314830313165+CDS,intron-Distal4.147443.49332HepG2PPIG
chr63031319930313288+CDS,intron-Distal,intron-Proximal3.972254.86518HepG2BUD13
chr63031307330313080+CDS,intron-Proximal3.9397310.26816K562DDX3X
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RPP21 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RPP21 is not available on ENCORE database.

  • 89 RBPs can affect the levels of RPP21.  








The Knockdown/knockout RNA-Seq assay for RPP21 is not available on ENCORE database.





89 RBPs can affect the gene expression of RPP21 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RPP21ENSG00000241370.1414.56210174.659201.246904.675303.45720HepG2BCCIP
RPP21ENSG00000241370.1336.30110245.724100.452602.827602.17910HepG2CELF1
RPP21ENSG00000241370.1314.09730171.761400.870702.025801.35350HepG2DDX55
RPP21ENSG00000241370.1250.92300143.943700.801603.906503.08270HepG2DNAJC21
RPP21ENSG00000241370.1231.51950142.700700.698004.625903.81880HepG2DNAJC2
RPP21ENSG00000241370.1249.97020368.14590-0.558502.630802.00390HepG2GPKOW
RPP21ENSG00000241370.1254.62750160.139800.669002.921701.51220HepG2HNRNPA0
RPP21ENSG00000241370.1232.47050145.323100.677703.191402.50410HepG2HNRNPA1
RPP21ENSG00000241370.1261.26750161.654300.692502.303601.66560HepG2HNRNPC
RPP21ENSG00000241370.1338.38180240.641300.491703.554002.79720HepG2HNRNPL
RPP21ENSG00000241370.1281.67470160.584900.810606.459705.56520HepG2HNRNPU
RPP21ENSG00000241370.1238.68760164.030600.541103.341102.54130HepG2ILF2
RPP21ENSG00000241370.1273.50840180.425800.600102.699501.52450HepG2KHDRBS1
RPP21ENSG00000241370.1260.95120167.916600.635902.968401.79380HepG2LARP7
RPP21ENSG00000241370.1366.34410261.965100.483703.167402.35350HepG2NOL12
RPP21ENSG00000241370.1241.68500138.237800.805903.063601.53400HepG2NOLC1
RPP21ENSG00000241370.1261.19230172.926400.594902.085801.33150HepG2PABPC1
RPP21ENSG00000241370.1301.76310143.227301.0750010.180108.81530HepG2PPIL4
RPP21ENSG00000241370.1326.13640250.077100.383001.818301.32180HepG2PUF60
RPP21ENSG00000241370.1396.90010265.477800.580105.380204.60930HepG2PUM1
RPP21ENSG00000241370.1377.57280265.277700.509203.259902.53170HepG2PUM2
RPP21ENSG00000241370.1336.18970202.486400.731403.806402.63090HepG2RBM27
RPP21ENSG00000241370.1291.60070164.428500.826403.934702.66700HepG2RCC2
RPP21ENSG00000241370.1252.38140180.562700.483002.033201.49900HepG2RPS19
RPP21ENSG00000241370.1292.62740190.627900.618202.748201.67760HepG2RPS5
RPP21ENSG00000241370.1276.12010143.002500.949208.015307.00470HepG2SAFB2
RPP21ENSG00000241370.1751.85780384.714900.966608.617407.37560HepG2SF3A3
RPP21ENSG00000241370.1342.02200239.805400.512103.698002.90620HepG2SLBP
RPP21ENSG00000241370.1275.72160166.755800.725405.286404.44580HepG2SMN1
RPP21ENSG00000241370.1253.46560165.956500.610902.307501.44170HepG2SMNDC1
RPP21ENSG00000241370.1205.71130285.46990-0.472702.278801.83890HepG2SRSF1
RPP21ENSG00000241370.1401.88020246.926600.702603.932803.20930HepG2SRSF5
RPP21ENSG00000241370.1394.56390280.813400.490503.734803.03150HepG2SUCLG1
RPP21ENSG00000241370.1176.37630256.61430-0.540902.753302.19420HepG2TAF15
RPP21ENSG00000241370.1275.28090156.003400.819203.869203.29910HepG2TIAL1
RPP21ENSG00000241370.1301.31540157.435400.936407.201206.36560HepG2TRIM56
RPP21ENSG00000241370.1361.65810244.331000.565703.577302.57070HepG2TUFM
RPP21ENSG00000241370.1555.40410370.030700.585803.352502.66650HepG2U2AF1
RPP21ENSG00000241370.1585.28090329.398900.829207.639906.72550HepG2UTP3
RPP21ENSG00000241370.1270.82980170.300600.669202.928201.79400HepG2XPO5
RPP21ENSG00000241370.1364.75680168.264501.116104.154703.27400HepG2XRN2
RPP21ENSG00000241370.1590.53010375.236200.654108.543107.71820HepG2ZNF622
RPP21ENSG00000241370.11614.61000768.034101.0718033.4853031.59190K562AGGF1
RPP21ENSG00000241370.11119.01500843.963300.406903.559902.40980K562AKAP8
RPP21ENSG00000241370.11418.43800799.176700.8276012.8728011.31740K562AKAP8L
RPP21ENSG00000241370.11136.43770838.533400.438505.212803.91590K562ATP5C1
RPP21ENSG00000241370.1703.52050531.528600.404303.415701.92330K562BCCIP
RPP21ENSG00000241370.1796.84430513.639000.633408.665006.93590K562BCLAF1
RPP21ENSG00000241370.1554.02990314.298200.817707.967205.91600K562CIRBP
RPP21ENSG00000241370.11211.793901000.539400.276302.621401.54570K562CPEB4
RPP21ENSG00000241370.1580.46360389.671700.574804.933403.46410K562CSTF2
RPP21ENSG00000241370.11029.31900778.587100.402703.492202.12920K562DDX21
RPP21ENSG00000241370.1572.98540450.382600.347202.671801.37800K562DDX27
RPP21ENSG00000241370.11445.684801035.050300.482007.766606.75070K562DDX47
RPP21ENSG00000241370.11107.55600859.956100.364902.904302.00540K562DKC1
RPP21ENSG00000241370.1654.67420382.521000.775104.056802.47570K562EEF2
RPP21ENSG00000241370.1603.93530369.500900.708705.743304.39890K562EFTUD2
RPP21ENSG00000241370.1345.84230206.528000.743705.650804.52810K562EIF3G
RPP21ENSG00000241370.1992.61440585.041400.762609.291507.63830K562FIP1L1
RPP21ENSG00000241370.1101.92250194.67660-0.933604.323403.39580K562G3BP2
RPP21ENSG00000241370.11650.050501103.679900.580103.351902.52280K562GRSF1
RPP21ENSG00000241370.1732.58910481.225100.606204.561503.34260K562HNRNPM
RPP21ENSG00000241370.1715.53720293.404501.286004.472103.03880K562IGF2BP2
RPP21ENSG00000241370.1470.08620298.369800.655705.430803.65950K562IGF2BP3
RPP21ENSG00000241370.11139.21100848.117700.425604.081703.05290K562KIF1C
RPP21ENSG00000241370.1447.42020308.202500.537703.851702.85220K562MAGOH
RPP21ENSG00000241370.11109.76200811.864300.450803.779402.45780K562MAK16
RPP21ENSG00000241370.1499.92150307.553900.700806.564005.06120K562MATR3
RPP21ENSG00000241370.11168.86450950.107200.298802.214701.41640K562MBNL1
RPP21ENSG00000241370.1947.94670665.957100.509302.257501.48030K562NAA15
RPP21ENSG00000241370.1633.14570364.448200.796705.520803.54550K562NONO
RPP21ENSG00000241370.11269.33670592.912201.098106.814905.04820K562PABPN1
RPP21ENSG00000241370.1476.69950301.339800.661605.789103.76020K562PCBP1
RPP21ENSG00000241370.1476.82110274.195800.798106.965005.39100K562PCBP2
RPP21ENSG00000241370.11077.79880664.166900.698408.114706.53720K562PPIG
RPP21ENSG00000241370.11154.70010704.959200.711802.956701.43990K562PPP1R8
RPP21ENSG00000241370.1799.43710359.570701.152608.069806.78300K562PRPF8
RPP21ENSG00000241370.1582.37090299.449600.9595012.4007011.04520K562PTBP1
RPP21ENSG00000241370.11978.70110792.546601.3199029.7965027.99270K562PUS1
RPP21ENSG00000241370.11289.13690772.231700.7392013.0929011.79910K562RBM15
RPP21ENSG00000241370.1518.59120287.052200.853208.536906.94070K562RBM22
RPP21ENSG00000241370.1569.49860366.153700.637103.799502.83890K562RPS19
RPP21ENSG00000241370.1341.15680202.375200.753305.981304.69000K562SF3B4
RPP21ENSG00000241370.1544.36330359.200600.599704.105302.06350K562SRP68
RPP21ENSG00000241370.1718.14300293.577701.2904021.1704019.22970K562SRSF1
RPP21ENSG00000241370.1463.61170346.288400.420802.322701.37250K562SRSF4
RPP21ENSG00000241370.1513.79860277.304800.889608.813706.84430K562SRSF5
RPP21ENSG00000241370.1530.62740347.946300.608703.187402.09490K562SUPV3L1
RPP21ENSG00000241370.1588.32830297.082500.985708.510107.18250K562TARDBP
RPP21ENSG00000241370.1541.39830286.579400.917706.036504.75760K562TIA1
RPP21ENSG00000241370.1588.40580281.307901.0646012.504409.61330K562TRA2A
RPP21ENSG00000241370.11509.868601262.458500.258102.801201.52260K562TROVE2
RPP21ENSG00000241370.1854.841001043.45980-0.287602.812102.08820K562UPF1
RPP21ENSG00000241370.1609.33310375.244300.699305.493203.57470K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RPP21 is not available on ENCORE database.





48 RBPs can affect the splicing of RPP21 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERPP21ENSG00000241370.1chr6+303130743031317530312910303130053031326730313706-0.079000.000010.00013excludedK562AQR
SERPP21ENSG00000241370.1chr6+303132673031370630313074303131753031420830314270-0.121000.002930.07024excludedHepG2SF3A3
SERPP21ENSG00000241370.1chr6+303130983031317530312931303130053031326730313350-0.103000.006470.08492excludedK562HNRNPC
A5SSRPP21ENSG00000241370.1chr6+303130743031335030313074303131753031420830314334-0.323000.000000.00004shorterHepG2U2AF2
A5SSRPP21ENSG00000241370.1chr6+303130743031335030313074303131753031420830314334-0.252000.000000.00000shorterHepG2U2AF1
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.094000.000160.01067includedHepG2AKAP1
RIRPP21ENSG00000241370.1chr6+303130743031433430313074303133503031420830314334-0.116000.000000.00019excludedK562NONO
RIRPP21ENSG00000241370.1chr6+3031307430313350303130743031317530313267303133500.110000.000800.05580includedHepG2DDX6
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.104000.000140.01351includedHepG2DDX6
RIRPP21ENSG00000241370.1chr6+3031293130313164303129313031300530313074303131640.089000.001780.09750includedHepG2HNRNPL
RIRPP21ENSG00000241370.1chr6+303130743031433430313074303133503031420830314334-0.161000.000050.00723excludedHepG2HNRNPL
RIRPP21ENSG00000241370.1chr6+3031307430313350303130743031317530313267303133500.066000.000900.00676includedK562PUS1
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.078000.000160.00143includedK562PUS1
RIRPP21ENSG00000241370.1chr6+3031307430314334303130743031335030314208303143340.074000.000000.00000includedK562PUS1
RIRPP21ENSG00000241370.1chr6+3031307430313350303130743031317530313267303133500.150000.000010.00022includedHepG2SF3A3
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.155000.000000.00000includedK562HNRNPC
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.141000.000000.00005includedHepG2DDX3X
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.105000.000620.02638includedK562SF3B1
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.099000.003270.02442includedHepG2U2AF2
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.071000.003250.06161includedK562SRSF1
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.141000.000340.06328includedHepG2XPO5
RIRPP21ENSG00000241370.1chr6+303129353031317530312935303130053031307430313175-0.061000.001080.05166excludedK562NCBP2
RIRPP21ENSG00000241370.1chr6+3031307430314334303130743031335030314208303143340.066000.000040.01430includedK562LARP7
RIRPP21ENSG00000241370.1chr6+3031307430314334303130743031335030314208303143340.067000.000020.00303includedK562PHF6
RIRPP21ENSG00000241370.1chr6+303130743031433430313074303133503031420830314334-0.113000.000010.00187excludedK562UCHL5
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.128000.000000.00008includedK562PRPF8
RIRPP21ENSG00000241370.1chr6+3031307430313350303130743031317530313267303133500.098000.005830.08553includedHepG2IGF2BP3
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.163000.000010.00065includedHepG2IGF2BP3
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.079000.001340.04340includedHepG2MATR3
RIRPP21ENSG00000241370.1chr6+3031307430313350303130743031317530313267303133500.154000.004440.05015includedHepG2PCBP1
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.125000.001020.02572includedHepG2SRSF1
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.116000.001010.01346includedHepG2QKI
RIRPP21ENSG00000241370.1chr6+303130743031433430313074303133503031420830314334-0.108000.000000.00169excludedK562XRN2
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.119000.000910.04937includedHepG2HNRNPA1
RIRPP21ENSG00000241370.1chr6+3031307430313350303130743031317530313267303133500.337000.000000.00028includedK562RBM22
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.157000.000000.00001includedK562BUD13
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.052000.005110.04485includedK562AKAP8L
RIRPP21ENSG00000241370.1chr6+3031307430314334303130743031335030314208303143340.080000.002870.02799includedHepG2TAF15
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.118000.000540.00683includedHepG2U2AF1
RIRPP21ENSG00000241370.1chr6+303130743031433430313074303133503031420830314334-0.086000.001220.04994excludedK562SUPV3L1
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.051000.009290.07926includedK562RBM15
RIRPP21ENSG00000241370.1chr6+3031307430313350303130743031317530313267303133500.090000.006540.07975includedHepG2G3BP1
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.180000.000000.00000includedHepG2G3BP1
RIRPP21ENSG00000241370.1chr6+3031307430314334303130743031335030314208303143340.084000.000070.00264includedHepG2G3BP1
RIRPP21ENSG00000241370.1chr6+303130743031335030313074303131753031326730313350-0.249000.000090.00925excludedK562EIF3G
RIRPP21ENSG00000241370.1chr6+3031307430313350303130743031317530313267303133500.118000.005920.09059includedHepG2KHSRP
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.101000.000220.00742includedHepG2KHSRP
RIRPP21ENSG00000241370.1chr6+3031307430314334303130743031335030314208303143340.056000.000160.02216includedK562XRCC6
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.162000.000030.00311includedHepG2HNRNPC
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.178000.000010.00043includedHepG2TIAL1
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.184000.000000.00000includedHepG2NCBP2
RIRPP21ENSG00000241370.1chr6+3031307430314334303130743031335030314208303143340.066000.000560.00896includedHepG2NCBP2
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.133000.000180.01617includedHepG2HNRNPU
RIRPP21ENSG00000241370.1chr6+303130743031433430313074303133503031420830314334-0.092000.000010.00132excludedK562CPSF6
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.220000.000000.00000includedHepG2SF3B4
RIRPP21ENSG00000241370.1chr6+3031307430314334303130743031335030314208303143340.063000.004690.03340includedHepG2SF3B4
RIRPP21ENSG00000241370.1chr6+3031307430314334303130743031335030314208303143340.061000.000550.01324includedHepG2FUBP3
RIRPP21ENSG00000241370.1chr6+3031307430313350303130743031317530313267303133500.092000.003460.05211includedHepG2FUBP3
RIRPP21ENSG00000241370.1chr6+3031307430313350303130743031317530313267303133500.252000.000000.00000includedHepG2RBM22
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.146000.000010.00020includedHepG2RBM22
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.111000.000030.00071includedHepG2HNRNPK
RIRPP21ENSG00000241370.1chr6+3031307430314334303130743031335030314208303143340.051000.007620.06902includedHepG2HNRNPK
RIRPP21ENSG00000241370.1chr6+3031307430314334303130743031335030314208303143340.068000.004430.07713includedHepG2PTBP1
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.129000.000010.00020includedK562EFTUD2
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.088000.000010.00240includedK562SAFB
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.120000.000840.06412includedK562FMR1
RIRPP21ENSG00000241370.1chr6+303130743031433430313074303133503031420830314334-0.083000.000040.01193excludedK562METAP2
RIRPP21ENSG00000241370.1chr6+3031307430314334303130743031335030314208303143340.094000.000000.00000includedK562AQR
RIRPP21ENSG00000241370.1chr6+3031307430313350303130743031317530313267303133500.185000.000000.00000includedK562AQR
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.359000.000000.00000includedK562AQR
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.145000.000000.00042includedHepG2LARP4
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.095000.000180.01068includedK562TARDBP
RIRPP21ENSG00000241370.1chr6+3031293530313175303129353031300530313074303131750.088000.000490.01222includedK562PTBP1
MXERPP21ENSG00000241370.1chr6+3031307430313350303142083031433430312931303130053031448930314634-0.096000.000290.007602includedK562PUS1
MXERPP21ENSG00000241370.1chr6+3031307430313175303132433031335030312907303130053031420830314334-0.100000.001440.012522includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RPP21 is not avaliable on ENCORE database.