RHOA

General Information

Gene Name       : RHOA
Gene ID             : ENSG00000067560.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: RHOA)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RHOAENSG00000067560.10425.53386.44405.99ENCSR000AEF
HepG2RHOAENSG00000067560.10181.55232.79207.17ENCSR985KAT
K562RHOAENSG00000067560.10194.64224.73209.69ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RHOA is not avaliable on ENCORE database.



Proteins bound to RNA
  • RHOA RNA is bound by 26 proteins.  







eCLIP assay for RHOA is not avaliable on ENCORE database.





26 proteins are bound to RHOA RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr34939718949397221-3'-UTR,intron-Distal3.0857811.17110K562FAM120A
chr34939767649397711-3'-UTR,CDS,intron-Distal3.345745.55036HepG2LARP4
chr34939668049396716-3'-UTR,intron-Distal4.7732138.29784K562IGF2BP2
chr34939759249397604-3'-UTR,intron-Distal3.482099.90371K562PABPC4
chr34939681949396888-3'-UTR,intron-Distal3.194515.45510HepG2FAM120A
chr34939680049396854-3'-UTR,intron-Distal3.4693117.10514K562IGF2BP2
chr34939741949397485-3'-UTR,intron-Distal,intron-Proximal4.1965114.21660HepG2IGF2BP1
chr34939745349397482-3'-UTR,intron-Distal,intron-Proximal4.9790650.31940K562IGF2BP2
chr34939727349397351-3'-UTR,intron-Distal,intron-Proximal3.617387.96472K562NOLC1
chr34941299949413025-3'-UTR,CDS,intron-Distal,intron-Proximal4.0493316.91650K562DDX3X
chr34939766949397716-3'-UTR,CDS,intron-Distal3.863645.71420K562RBM15
chr34939663549396686-3'-UTR,intron-Distal4.534548.16120HepG2IGF2BP3
chr34939741749397453-3'-UTR,intron-Distal4.7090968.76751K562IGF2BP2
chr34939761849397655-3'-UTR,CDS,intron-Distal3.822667.42445K562RPS3
chr34939753749397546-3'-UTR,intron-Distal,intron-Proximal3.7970733.99038K562PABPC4
chr34939748749397543-3'-UTR,intron-Distal,intron-Proximal5.1525023.85706K562IGF2BP1
chr34939732249397367-3'-UTR,intron-Distal,intron-Proximal4.6668113.58172K562IGF2BP1
chr34939669049396784-3'-UTR,intron-Distal3.514056.15198HepG2UPF1
chr34939672249396743-3'-UTR,intron-Distal3.202098.23356K562IGF2BP1
chr34939749749397558-3'-UTR,intron-Distal,intron-Proximal3.845033.35109HepG2TIAL1
chr34939673949396778-3'-UTR,intron-Distal3.1413822.57362K562FAM120A
chr34939766949397709-3'-UTR,CDS,intron-Distal3.2355913.12372HepG2SUB1
chr34939728649397308-3'-UTR,intron-Distal,intron-Proximal3.2811810.98201K562UPF1
chr34939701949397064-3'-UTR,intron-Distal4.7706017.68710HepG2SUB1
chr34939671649396730-3'-UTR,intron-Distal3.203766.04900K562IGF2BP2
chr34939682649396885-3'-UTR,intron-Distal3.96772400.00000K562FAM120A
chr34939988149399936-3'-UTR,CDS,intron-Distal,intron-Proximal4.140146.80869K562AQR
chr34939737249397417-3'-UTR,intron-Distal3.8242434.42327K562IGF2BP2
chr34939702749397155-3'-UTR,intron-Distal4.0546515.42531K562NOLC1
chr34939702749397058-3'-UTR,intron-Distal3.2425815.45467K562FAM120A
chr34939688549396926-3'-UTR,intron-Distal3.8194048.00521K562FAM120A
chr34939745949397481-3'-UTR,intron-Distal,intron-Proximal3.6654610.09891HepG2SUB1
chr34939724549397303-3'-UTR,intron-Distal,intron-Proximal4.651184.78313HepG2UPF1
chr34939662949396658-3'-UTR,intron-Distal3.8044413.04606K562UPF1
chr34939680049396824-3'-UTR,intron-Distal3.7604956.25112K562FAM120A
chr34939663749396680-3'-UTR,intron-Distal4.2813249.24904K562IGF2BP2
chr34939772849397776-3'-UTR,CDS,intron-Distal3.399663.79741HepG2GRWD1
chr34939741449397476-3'-UTR,intron-Distal,intron-Proximal4.023013.45012HepG2UPF1
chr34939702549397066-3'-UTR,intron-Distal3.0890717.78455K562UPF1
chr34939674349396780-3'-UTR,intron-Distal3.086497.41561K562IGF2BP1
chr34939724449397343-3'-UTR,intron-Distal,intron-Proximal4.4696927.97786HepG2SUB1
chr34939754649397604-3'-UTR,intron-Distal,intron-Proximal3.675068.28333K562NOLC1
chr34939992749400028-3'-UTR,CDS,intron-Distal,intron-Proximal3.018866.63579K562ZNF800
chr34939748949397538-3'-UTR,intron-Distal,intron-Proximal3.011795.74103K562TIA1
chr34939753849397578-3'-UTR,intron-Distal,intron-Proximal3.390148.36475K562TIA1
chr34939748849397537-3'-UTR,intron-Distal,intron-Proximal3.3574839.45993K562PABPC4
chr34939707149397146-3'-UTR,intron-Distal3.7703935.11331K562UPF1
chr34939724449397250-3'-UTR,intron-Distal,intron-Proximal3.2641120.55170K562YBX3
chr34939764549397761-3'-UTR,CDS,intron-Distal3.193178.72097HepG2G3BP1
chr34939754649397592-3'-UTR,intron-Distal,intron-Proximal5.88722400.00000K562PABPC4
chr34939699149397031-3'-UTR,intron-Distal3.2965823.30401K562PABPC4
chr34939730849397340-3'-UTR,intron-Distal,intron-Proximal4.0802720.87520K562UPF1
chr34939749949397579-3'-UTR,intron-Distal,intron-Proximal3.783037.41528K562APOBEC3C
chr34939708549397128-3'-UTR,intron-Distal5.6422418.07637K562RPS3
chr34939723849397290-3'-UTR,intron-Distal,intron-Proximal3.4773730.27148K562FAM120A
chr34939754349397659-3'-UTR,CDS,intron-Distal,intron-Proximal3.4904916.37340HepG2LARP4
chr34939761649397657-3'-UTR,CDS,intron-Distal4.3720514.39260HepG2SUB1
chr34939754549397607-3'-UTR,intron-Distal,intron-Proximal6.0964733.02200HepG2SUB1
chr34939677849396800-3'-UTR,intron-Distal3.7514347.60967K562FAM120A
chr34939767249397698-3'-UTR,CDS,intron-Distal3.279797.83335K562RPS3
chr34939736949397435-3'-UTR,intron-Distal5.6632912.48224HepG2IGF2BP3
chr34939743549397480-3'-UTR,intron-Distal,intron-Proximal5.1780310.31763HepG2IGF2BP3
chr34939658349396634-3'-UTR,intron-Distal5.0369225.35727K562IGF2BP1
chr34939706449397124-3'-UTR,intron-Distal8.1092146.99163HepG2SUB1
chr34939730549397357-3'-UTR,intron-Distal,intron-Proximal3.8889421.07265K562FAM120A
chr34939992849399990-3'-UTR,CDS,intron-Distal,intron-Proximal3.574599.28648HepG2G3BP1
chr34939698549397027-3'-UTR,intron-Distal3.1725723.56049K562FAM120A
chr34944931249449351-5'-UTR,intron-Distal,intron-Proximal3.554268.58246HepG2SUB1
chr34944926249449357-5'-UTR,intron-Distal,intron-Proximal3.2507514.20912K562GEMIN5
chr34944925049449409-5'-UTR,intron-Distal,intron-Proximal3.5230314.90309HepG2DDX3X
chr34944931949449401-5'-UTR,intron-Distal,intron-Proximal3.1427816.91201K562DDX3X
chr34944927749449327-5'-UTR,intron-Distal,intron-Proximal3.3295616.11531K562RPS3
chr34944926049449343-5'-UTR,intron-Distal,intron-Proximal3.145237.32105HepG2RPS3
chr34944925149449319-5'-UTR,intron-Distal,intron-Proximal3.1660729.66865K562DDX3X
chr34944920749449256-5'-UTR,intron-Distal3.874884.98250K562AQR
chr34941295849413018-CDS,intron-Distal3.109164.56061K562BUD13
chr34941287249412969-CDS,intron-Distal3.3026730.76447K562DDX3X
chr34940584149405862-CDS,intron-Distal,intron-Proximal3.427894.88100K562AQR
chr34941290849412987-CDS,intron-Distal3.685877.30054HepG2RPS3
chr34940590249405943-CDS,intron-Distal3.6487927.84266K562YBX3
chr34940581849405887-CDS,intron-Distal,intron-Proximal3.995806.82513HepG2PRPF8
chr34941286549412909-CDS,intron-Distal,intron-Proximal4.005409.47617K562RPS3
chr34940589849405902-CDS,intron-Distal3.006659.08817K562YBX3
chr34940590949405980-CDS,intron-Distal3.568228.79196HepG2G3BP1
chr34941286649412905-CDS,intron-Distal,intron-Proximal3.878156.53930HepG2G3BP1
chr34941296949412999-CDS,intron-Distal3.9177121.59623K562DDX3X
chr34941293849413012-CDS,intron-Distal4.606228.65034K562DROSHA
chr34940586549405889-CDS,intron-Distal3.2536220.33418K562YBX3
chr34941297749413012-CDS,intron-Distal4.990827.56262K562RPS3
chr34944789849447953-intron-Distal3.512224.08493K562HNRNPM
chr34944790949447966-intron-Distal3.659237.24726HepG2HNRNPM
chr34944800749448096-intron-Distal3.979065.62053HepG2HNRNPM
chr34944773949447775-intron-Distal4.021413.62366HepG2HNRNPM
chr34940579849405841-intron-Distal,intron-Proximal5.473858.88118K562AQR
chr34940599049406039-intron-Distal,intron-Proximal5.193166.02529K562SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RHOA is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RHOA is not available on ENCORE database.

  • 82 RBPs can affect the levels of RHOA.  








The Knockdown/knockout RNA-Seq assay for RHOA is not available on ENCORE database.





82 RBPs can affect the gene expression of RHOA :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RHOAENSG00000067560.65442.025404802.001900.180402.684702.08530HepG2ACO1
RHOAENSG00000067560.66612.673308117.38970-0.295801.938901.48450HepG2AKAP1
RHOAENSG00000067560.63791.700104824.36540-0.347506.848205.69830HepG2AKAP8L
RHOAENSG00000067560.66959.430607818.50220-0.167902.242001.61230HepG2AUH
RHOAENSG00000067560.63220.688304108.51330-0.351202.719301.82740HepG2BCLAF1
RHOAENSG00000067560.64491.327505873.68090-0.387103.912403.21350HepG2BOP1
RHOAENSG00000067560.64851.313106380.98500-0.395403.835402.93310HepG2CIRBP
RHOAENSG00000067560.66741.565907490.15130-0.151902.319001.63240HepG2DAZAP1
RHOAENSG00000067560.63799.202804441.05450-0.225203.784602.82800HepG2DDX19B
RHOAENSG00000067560.63612.862004648.91800-0.363802.655101.89460HepG2DDX55
RHOAENSG00000067560.63596.719504594.15310-0.353107.057006.07120HepG2DKC1
RHOAENSG00000067560.63882.147904771.69390-0.297607.110506.13360HepG2DNAJC2
RHOAENSG00000067560.65311.889207095.44050-0.417703.393302.68720HepG2EIF4A3
RHOAENSG00000067560.65759.207907078.95720-0.297702.590901.80160HepG2EIF4G2
RHOAENSG00000067560.67922.730608976.74740-0.180202.667602.07530HepG2ETF1
RHOAENSG00000067560.65711.054007051.77090-0.304202.462601.62420HepG2G3BP2
RHOAENSG00000067560.63470.931506113.13990-0.816608.350607.28190HepG2GPKOW
RHOAENSG00000067560.63878.075804860.33960-0.325703.560302.83990HepG2HNRNPA1
RHOAENSG00000067560.64137.548805406.22490-0.385804.504003.63310HepG2HNRNPC
RHOAENSG00000067560.65408.805606425.66620-0.248504.164303.30320HepG2HNRNPF
RHOAENSG00000067560.64839.522606726.80000-0.475105.996904.99770HepG2HNRNPK
RHOAENSG00000067560.64048.864904800.27050-0.245602.257301.39780HepG2HNRNPM
RHOAENSG00000067560.63440.005605370.48250-0.6426023.2723021.64840HepG2HNRNPU
RHOAENSG00000067560.62834.698506750.74820-1.2519029.7375027.81660HepG2IGF2BP2
RHOAENSG00000067560.65255.510106790.56180-0.369702.361501.44620HepG2KHSRP
RHOAENSG00000067560.65628.325107162.82980-0.347802.872102.20460HepG2MAGOH
RHOAENSG00000067560.65293.958607202.70430-0.444203.927803.18780HepG2MATR3
RHOAENSG00000067560.65876.426507372.19350-0.327202.518701.91300HepG2NCBP2
RHOAENSG00000067560.64252.946905813.24430-0.450903.015701.52020HepG2NKRF
RHOAENSG00000067560.64238.722505172.57790-0.287302.441701.73850HepG2NSUN2
RHOAENSG00000067560.63805.987205389.99530-0.502006.701904.33130HepG2NUP35
RHOAENSG00000067560.64975.180506564.61590-0.400003.557502.74470HepG2PABPC4
RHOAENSG00000067560.65225.824806635.24140-0.344507.518906.59680HepG2PCBP1
RHOAENSG00000067560.63539.972305301.66470-0.582704.248002.97780HepG2PCBP2
RHOAENSG00000067560.63829.781704790.04200-0.322804.954003.99700HepG2PPIL4
RHOAENSG00000067560.64916.348606751.66210-0.4577012.2259011.23760HepG2PTBP1
RHOAENSG00000067560.66371.864007526.56930-0.240305.569204.78900HepG2PUM1
RHOAENSG00000067560.64165.546904891.11570-0.231703.940103.22980HepG2PUS1
RHOAENSG00000067560.65225.647707312.09760-0.4847010.185909.09430HepG2QKI
RHOAENSG00000067560.65561.044506636.24360-0.255002.553601.90260HepG2RBM25
RHOAENSG00000067560.65593.570607513.90520-0.4258011.1197010.17170HepG2NELFE
RHOAENSG00000067560.65478.160206998.26580-0.353308.140307.16690HepG2RECQL
RHOAENSG00000067560.65123.771806922.29890-0.434005.898004.95520HepG2RPLP0
RHOAENSG00000067560.63082.029903779.40160-0.294303.003202.36640HepG2RPS19
RHOAENSG00000067560.63816.393105530.09970-0.535104.194303.20850HepG2RPS3A
RHOAENSG00000067560.64269.223304782.65470-0.163802.329501.73020HepG2SAFB2
RHOAENSG00000067560.63106.179003792.90430-0.288202.284201.42700HepG2SERBP1
RHOAENSG00000067560.67302.506805800.498200.332102.133201.53990HepG2SF3A3
RHOAENSG00000067560.64219.934705774.55660-0.452504.920804.00230HepG2SF3B1
RHOAENSG00000067560.65375.127707029.25150-0.387109.513708.51650HepG2SF3B4
RHOAENSG00000067560.64916.175705577.38790-0.182103.397702.69690HepG2SMN1
RHOAENSG00000067560.65992.890407337.05760-0.291906.525505.87340HepG2SRSF1
RHOAENSG00000067560.65119.574806313.06980-0.302306.032305.06730HepG2SRSF7
RHOAENSG00000067560.65837.940907357.58370-0.333807.883507.10360HepG2SSB
RHOAENSG00000067560.63934.419805685.29710-0.531106.072905.05750HepG2TARDBP
RHOAENSG00000067560.62844.450805218.44340-0.8755026.2521025.00660HepG2TIAL1
RHOAENSG00000067560.63645.204805144.15770-0.4969015.3212013.93280HepG2UPF1
RHOAENSG00000067560.65512.392204966.478100.150402.018901.49100HepG2UTP3
RHOAENSG00000067560.66871.042505657.585000.280207.537106.74930HepG2ZNF622
RHOAENSG00000067560.614577.575908932.968400.7064034.3118032.38470K562AGGF1
RHOAENSG00000067560.613254.656309816.137800.433205.860804.30020K562AKAP8
RHOAENSG00000067560.611811.140009295.196900.345504.010503.22220K562AKAP8L
RHOAENSG00000067560.612174.124509752.971500.319805.447304.11300K562ATP5C1
RHOAENSG00000067560.612414.5457010675.262700.217702.447701.35370K562CCDC124
RHOAENSG00000067560.67837.619509619.30320-0.295505.795504.90300K562DDX47
RHOAENSG00000067560.612480.8875010002.057300.319305.955404.60040K562DKC1
RHOAENSG00000067560.62594.703803732.16700-0.524403.175902.09110K562EIF3A
RHOAENSG00000067560.64129.382904750.66970-0.202202.276301.54980K562EIF3G
RHOAENSG00000067560.64472.663206110.79990-0.450205.685104.51280K562EIF4A3
RHOAENSG00000067560.68883.381107247.806200.293502.755301.90890K562FIP1L1
RHOAENSG00000067560.65515.330406355.00100-0.204402.457801.88090K562FXR1
RHOAENSG00000067560.64064.906706561.66910-0.6908015.0519013.74490K562HNRNPC
RHOAENSG00000067560.66731.459408048.37630-0.257803.505302.50070K562HNRNPU
RHOAENSG00000067560.613949.080609864.392700.499808.623706.95830K562KIF1C
RHOAENSG00000067560.613020.540509442.760100.463405.660803.93590K562MAK16
RHOAENSG00000067560.65999.840707056.15120-0.234002.196501.38370K562MATR3
RHOAENSG00000067560.64307.011306620.48530-0.6202011.489009.62430K562METAP2
RHOAENSG00000067560.612282.423707745.703300.665007.017605.36770K562NAA15
RHOAENSG00000067560.64336.947605691.32330-0.392105.809204.65200K562POLR2G
RHOAENSG00000067560.64654.753905883.39920-0.337903.631102.57560K562PSIP1
RHOAENSG00000067560.619214.186809218.011401.0595015.5866014.33720K562PUS1
RHOAENSG00000067560.614960.230708981.789900.7360025.1430023.27580K562RBM15
RHOAENSG00000067560.64280.175605368.68490-0.326904.070702.86460K562RCC2
RHOAENSG00000067560.64085.458405014.19280-0.295502.013501.32200K562RPS19
RHOAENSG00000067560.64758.721806923.48770-0.540906.895405.22440K562RPS3
RHOAENSG00000067560.64171.619305071.10960-0.281702.820001.72680K562SAFB
RHOAENSG00000067560.65407.908906733.90280-0.316403.830803.00610K562SRSF1
RHOAENSG00000067560.64846.485006683.93560-0.463807.334105.49500K562SRSF4
RHOAENSG00000067560.63801.836004765.74320-0.326002.467501.51380K562SUPV3L1
RHOAENSG00000067560.63750.319605658.74350-0.593507.458505.86300K562TIAL1
RHOAENSG00000067560.613990.608809346.379400.581902.808901.50250K562UTP18
RHOAENSG00000067560.66615.656007391.38200-0.160002.507001.69940K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RHOA is not available on ENCORE database.





5 RBPs can affect the splicing of RHOA :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERHOAENSG00000067560.6chr3-4940586049406031493965774939781549412866494130240.404000.000860.01081includedK562AQR
SERHOAENSG00000067560.6chr3-493999284940005949397324493978154941286649413049-0.115000.000000.00000excludedK562SUPV3L1
SERHOAENSG00000067560.6chr3-493999164940005949396577493978154941286649413024-0.447000.000160.00368excludedK562PUS1
A3SSRHOAENSG00000067560.6chr3-4939836049398584493983604939849949399928494001690.271000.006060.03423longerK562AQR
A3SSRHOAENSG00000067560.6chr3-4941286649413094494128664941302449449252494495300.064000.000000.00000longerK562AQR
MXERHOAENSG00000067560.6chr3-4940586049405981494128664941302449397554493978154944925249449403-0.052000.000870.017782includedK562U2AF1
MXERHOAENSG00000067560.6chr3-49399834494000594940586049405948493975544939781549412866494130240.349000.006520.044801includedK562AQR
MXERHOAENSG00000067560.6chr3-49399834494000594940586049406049493975544939781549412866494130240.334000.010190.064341includedK562AQR
MXERHOAENSG00000067560.6chr3-49399834494000594940586049406031493975544939781549412866494130240.416000.000710.006731includedK562AQR
MXERHOAENSG00000067560.6chr3-49399834494000594940586049406096493975544939781549412866494130240.359000.004790.034641includedK562AQR
MXERHOAENSG00000067560.6chr3-49399916494000594940586049405948493975544939781549412866494130240.390000.002260.018461includedK562AQR
MXERHOAENSG00000067560.6chr3-49399916494000594940586049406049493975544939781549412866494130240.376000.003180.024601includedK562AQR
MXERHOAENSG00000067560.6chr3-49399916494000594940586049406031493975544939781549412866494130240.453000.000220.002411includedK562AQR
MXERHOAENSG00000067560.6chr3-49399916494000594940586049406096493975544939781549412866494130240.399000.001560.013411includedK562AQR
MXERHOAENSG00000067560.6chr3-4940586049405981494128664941302449397554493978154944925249449403-0.051000.000010.000102includedHepG2U2AF2
MXERHOAENSG00000067560.6chr3-49399928494000594941286649413024493973244939781549449252494493610.097000.000640.017341includedK562SUPV3L1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RHOA is not avaliable on ENCORE database.