PRPF31

General Information

Gene Name       : PRPF31
Gene ID             : ENSG00000105618.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PRPF31)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PRPF31ENSG00000105618.1335.0445.2140.12ENCSR000AEF
HepG2PRPF31ENSG00000105618.1378.2039.4558.83ENCSR985KAT
K562PRPF31ENSG00000105618.1378.9556.8567.90ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PRPF31 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PRPF31 RNA is bound by 21 proteins.  







eCLIP assay for PRPF31 is not avaliable on ENCORE database.





21 proteins are bound to PRPF31 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr195463484054635041+3'-UTR,CDS3.299783.44854HepG2LARP4
chr195463488554635059+3'-UTR4.552965.93974HepG2UPF1
chr195462164554621813+5'-UTR,CDS,intron-Proximal4.163309.34199K562SRSF1
chr195462165654621827+5'-UTR,CDS5.0913230.63258K562UCHL5
chr195463236654632457+CDS,intron-Proximal6.3474713.61356HepG2EFTUD2
chr195463150054631561+CDS3.420054.41784HepG2GRWD1
chr195462172354621805+CDS3.2956415.60651K562ZNF622
chr195463242154632463+CDS,intron-Proximal3.306515.12722K562BUD13
chr195462526254625319+CDS3.772786.15459HepG2GRWD1
chr195462523854625315+CDS,intron-Proximal3.003585.35460K562GRWD1
chr195463259854632650+CDS,intron-Proximal4.289939.18646HepG2SF3A3
chr195463259254632659+CDS,intron-Proximal5.3288814.54650K562SF3B4
chr195462595954626062+CDS,intron-Proximal3.295496.49827K562PRPF8
chr195463242754632494+CDS,intron-Proximal3.730167.67169K562SF3B4
chr195462167254621815+CDS3.228284.58091HepG2GRWD1
chr195462170754621812+CDS3.467594.46749K562RBM15
chr195462523854625251+CDS,intron-Proximal3.171625.41277K562UCHL5
chr195462172354621808+CDS4.010673.11282HepG2G3BP1
chr195462597154625990+CDS,intron-Proximal3.653076.87160K562AQR
chr195463257654632662+CDS,intron-Proximal5.214109.24251HepG2EFTUD2
chr195462587754625894+CDS3.619916.84505K562ZNF622
chr195463269054632768+CDS,intron-Proximal3.310037.97261K562PRPF8
chr195463260454632685+CDS,intron-Proximal3.166369.43119K562PRPF8
chr195462525154625320+CDS3.4968510.33108K562UCHL5
chr195462689054626915+CDS3.608735.10442K562YBX3
chr195463251454632575+CDS,intron-Proximal4.135688.79725K562PRPF8
chr195463249854632612+CDS,intron-Proximal5.0088034.76432HepG2PRPF8
chr195462196954622015+CDS,intron-Proximal4.208558.98140K562DDX24
chr195462200054622012+CDS3.568746.77066K562UCHL5
chr195463243154632515+CDS,intron-Proximal3.094013.61795HepG2SRSF1
chr195462527854625322+CDS3.3783810.78542K562ZNF622
chr195462197254622000+CDS3.142074.80218K562UCHL5
chr195462523854625312+CDS,intron-Proximal4.0980511.82968K562DDX24
chr195462590654625953+CDS3.057853.68829K562YBX3
chr195462195654622015+CDS,intron-Proximal3.938374.12796K562LIN28B
chr195462173754621825+CDS3.050703.34010HepG2PPIG
chr195463258154632677+CDS,intron-Proximal5.9171427.81249K562EFTUD2
chr195463273354632783+CDS,intron-Proximal4.532878.11807HepG2PRPF8
chr195462646054626508+intron-Distal3.110696.13643K562AQR
chr195462635954626537+intron-Distal3.356933.29499HepG2PRPF4
chr195463002854630097+intron-Distal,intron-Proximal5.382137.81704HepG2RBM22
chr195463206354632141+intron-Distal3.266654.13050K562HNRNPK
chr195463227854632316+intron-Distal4.232095.42080K562EFTUD2
chr195463257554632604+intron-Proximal4.524809.53843K562PRPF8
chr195463002554630081+intron-Proximal4.594547.04874K562EFTUD2
chr195463001554630075+intron-Proximal5.675357.41664HepG2EFTUD2
chr195463136654631413+intron-Proximal3.041755.12902K562SF3B4
chr195462600954626042+intron-Proximal4.722426.08900K562BUD13
chr195463256454632646+intron-Proximal4.560986.32943HepG2SF3B4
chr195463274554632755+intron-Proximal5.284594.65563K562AQR
chr195463235154632431+intron-Proximal4.4805416.14779HepG2SF3B4
chr195463275554632785+intron-Proximal5.360594.65563K562AQR
chr195462601154626058+intron-Proximal5.158315.43043K562EFTUD2
chr195463236354632427+intron-Proximal4.6359016.21903K562SF3B4
chr195462599054626035+intron-Proximal6.2481214.09387K562AQR
chr195463237354632421+intron-Proximal3.980816.34541K562BUD13
chr195463003654630072+intron-Proximal4.470405.02679K562BUD13
chr195462999754630071+intron-Proximal6.0069813.28065K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PRPF31 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PRPF31 is not available on ENCORE database.

  • 87 RBPs can affect the levels of PRPF31.  








The Knockdown/knockout RNA-Seq assay for PRPF31 is not available on ENCORE database.





87 RBPs can affect the gene expression of PRPF31 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PRPF31ENSG00000105618.91331.18140866.802100.618805.003204.31390HepG2AKAP1
PRPF31ENSG00000105618.9888.84210572.667100.634104.314003.14160HepG2BCCIP
PRPF31ENSG00000105618.91291.28370886.964200.541805.520604.71030HepG2BOP1
PRPF31ENSG00000105618.9667.30410388.498000.780304.717803.71350HepG2CNOT7
PRPF31ENSG00000105618.9460.14290814.24540-0.823405.735104.77800HepG2CPSF6
PRPF31ENSG00000105618.9402.07620542.37270-0.431802.263701.44740HepG2DDX24
PRPF31ENSG00000105618.9536.85100396.025900.438804.175503.40560HepG2DNAJC2
PRPF31ENSG00000105618.9535.52160847.25490-0.661908.590607.26800HepG2EIF4G1
PRPF31ENSG00000105618.91017.663701403.04460-0.463307.101706.21360HepG2ETF1
PRPF31ENSG00000105618.9389.38350527.97320-0.439302.842501.68370HepG2FASTKD2
PRPF31ENSG00000105618.91124.14520764.707800.555704.758703.86710HepG2FXR1
PRPF31ENSG00000105618.9608.63530922.91200-0.600603.022302.35670HepG2GPKOW
PRPF31ENSG00000105618.9599.46780789.20140-0.396702.746301.81420HepG2HNRNPA2B1
PRPF31ENSG00000105618.9472.80920320.748700.559703.074201.59880HepG2HNRNPAB
PRPF31ENSG00000105618.91121.17820718.602500.641606.090405.08410HepG2HNRNPK
PRPF31ENSG00000105618.9979.22980782.102800.324203.939103.14570HepG2HNRNPL
PRPF31ENSG00000105618.9673.55220880.76080-0.387002.182601.61700HepG2HNRNPLL
PRPF31ENSG00000105618.9730.52020445.703000.712708.948907.90700HepG2HNRNPU
PRPF31ENSG00000105618.9697.33900504.210700.467702.457901.32020HepG2LIN28B
PRPF31ENSG00000105618.91038.31420769.189700.432702.674602.05380HepG2MATR3
PRPF31ENSG00000105618.9643.71850898.47720-0.481102.425801.52330HepG2MTPAP
PRPF31ENSG00000105618.9553.59960781.03460-0.496502.972502.19770HepG2NSUN2
PRPF31ENSG00000105618.9489.66730700.84460-0.517302.990202.24130HepG2PABPC4
PRPF31ENSG00000105618.9598.19800397.530200.589506.141905.07680HepG2PPIL4
PRPF31ENSG00000105618.9444.18090761.39930-0.777506.118605.36800HepG2PTBP1
PRPF31ENSG00000105618.9635.50470862.23540-0.440202.439701.81040HepG2PUM2
PRPF31ENSG00000105618.9384.80660780.16650-1.0196021.1542019.74260HepG2PUS1
PRPF31ENSG00000105618.9448.74860824.45200-0.877505.510304.67350HepG2QKI
PRPF31ENSG00000105618.9824.713701172.67890-0.507806.576705.85950HepG2RBM22
PRPF31ENSG00000105618.9574.13170748.30450-0.382202.207401.59950HepG2RBM25
PRPF31ENSG00000105618.9819.12940579.359500.499502.593001.63380HepG2RBM27
PRPF31ENSG00000105618.9688.29670490.211700.489503.796303.08680HepG2RPS19
PRPF31ENSG00000105618.9711.94620534.270100.414102.039501.34620HepG2RPS2
PRPF31ENSG00000105618.9539.81380390.055200.468702.254401.53110HepG2RPS3A
PRPF31ENSG00000105618.9764.25480545.430800.486602.885501.78570HepG2RPS5
PRPF31ENSG00000105618.9588.35050396.913800.567806.330505.41600HepG2SAFB2
PRPF31ENSG00000105618.9779.197401088.12030-0.481802.804902.12680HepG2SF3A3
PRPF31ENSG00000105618.9558.65390871.72230-0.641904.576503.68600HepG2SF3B1
PRPF31ENSG00000105618.9662.37520462.861100.517006.255505.34900HepG2SMN1
PRPF31ENSG00000105618.9948.014401324.48580-0.482507.714706.99450HepG2SRFBP1
PRPF31ENSG00000105618.91148.79510802.609900.517308.427007.40970HepG2SRSF5
PRPF31ENSG00000105618.9747.184101149.94640-0.6220011.2203010.32210HepG2SSB
PRPF31ENSG00000105618.9546.99270339.286100.688904.651903.18800HepG2STIP1
PRPF31ENSG00000105618.91251.72120912.729600.455607.903806.94180HepG2SUCLG1
PRPF31ENSG00000105618.9447.76970743.79650-0.732205.483004.73970HepG2TAF15
PRPF31ENSG00000105618.9636.01990858.73070-0.433102.367701.68980HepG2TARDBP
PRPF31ENSG00000105618.9650.94140433.055500.587905.693805.02670HepG2TIAL1
PRPF31ENSG00000105618.9710.13600436.957100.7005010.248709.26830HepG2TRIM56
PRPF31ENSG00000105618.91007.77410794.184300.343502.963602.05580HepG2TUFM
PRPF31ENSG00000105618.9462.90260331.104000.483302.778202.01660HepG2UCHL5
PRPF31ENSG00000105618.9841.79770551.757100.609304.745503.80430HepG2XRN2
PRPF31ENSG00000105618.9612.44220779.23000-0.347503.391002.65920HepG2ZC3H8
PRPF31ENSG00000105618.9723.226001061.31160-0.553309.989509.11220HepG2ZNF622
PRPF31ENSG00000105618.91505.500101233.489200.287403.452002.83080K562AGGF1
PRPF31ENSG00000105618.91267.77230935.794400.437903.430001.93260K562BCCIP
PRPF31ENSG00000105618.9819.422801057.68820-0.368203.103502.27210K562CPSF6
PRPF31ENSG00000105618.9861.23140686.115300.327802.468001.47690K562CSTF2
PRPF31ENSG00000105618.92704.999603279.88670-0.278002.692401.73110K562CELF1
PRPF31ENSG00000105618.92448.196302104.069000.218402.509001.88410K562DDX47
PRPF31ENSG00000105618.91386.179001706.60950-0.300003.395702.61150K562EIF2S2
PRPF31ENSG00000105618.9807.45160538.392000.584607.023605.76660K562EIF3G
PRPF31ENSG00000105618.91161.26770799.977400.537605.620104.45440K562EIF4A3
PRPF31ENSG00000105618.9420.27610575.98610-0.454703.031801.35300K562FASTKD2
PRPF31ENSG00000105618.9648.34170896.84740-0.468103.334702.07700K562FKBP4
PRPF31ENSG00000105618.9795.338401076.20500-0.436303.550502.57750K562FMR1
PRPF31ENSG00000105618.91459.10920831.945300.8104017.8365016.40990K562FXR1
PRPF31ENSG00000105618.9184.18450409.34580-1.152209.174507.73580K562G3BP2
PRPF31ENSG00000105618.9801.835601009.81860-0.332702.316301.58940K562GPKOW
PRPF31ENSG00000105618.91588.491101962.59000-0.305102.312101.58050K562HSPD1
PRPF31ENSG00000105618.9593.10820862.29420-0.539903.311602.28100K562KRR1
PRPF31ENSG00000105618.91111.76150654.693500.7639010.833009.10230K562MAGOH
PRPF31ENSG00000105618.91888.026701525.882300.307103.107602.13470K562MBNL1
PRPF31ENSG00000105618.91673.439101987.92120-0.248403.986703.10990K562NSUN2
PRPF31ENSG00000105618.91337.473501888.46210-0.497702.457501.31260K562PABPC1
PRPF31ENSG00000105618.91199.736201648.24880-0.458202.648801.83690K562PCBP3
PRPF31ENSG00000105618.91029.394801264.24060-0.296502.410901.66500K562POLR2G
PRPF31ENSG00000105618.92377.072103095.76820-0.381104.706903.28200K562PUM1
PRPF31ENSG00000105618.91466.911201240.230000.242102.209501.66960K562RBM15
PRPF31ENSG00000105618.9798.22830594.539800.424902.818201.42750K562RBM34
PRPF31ENSG00000105618.9902.35350641.706800.491703.983402.63800K562NELFE
PRPF31ENSG00000105618.9814.34870561.070800.537402.632401.65760K562RPS3
PRPF31ENSG00000105618.91227.089201961.41440-0.6767015.1904013.39410K562SF3A3
PRPF31ENSG00000105618.9700.72150960.42200-0.454802.993901.98100K562SF3B1
PRPF31ENSG00000105618.9562.11970425.435600.401802.857201.98830K562SF3B4
PRPF31ENSG00000105618.91432.657302009.49730-0.4881011.157809.42920K562SRPK2
PRPF31ENSG00000105618.91498.89510623.634701.2650030.5788028.23380K562SRSF1
PRPF31ENSG00000105618.9729.86420541.612600.430303.115401.98130K562SRSF4
PRPF31ENSG00000105618.9423.35030555.37210-0.391602.575301.34580K562SSB
PRPF31ENSG00000105618.91472.137401899.29410-0.367603.054401.61730K562SSRP1
PRPF31ENSG00000105618.91312.283101737.13210-0.404603.198001.83510K562STAU1
PRPF31ENSG00000105618.91556.210901268.097200.295302.634001.83550K562SYNCRIP
PRPF31ENSG00000105618.9972.16960631.069800.623305.119004.14200K562TARDBP
PRPF31ENSG00000105618.9907.17650608.761500.575405.420904.21610K562TIA1
PRPF31ENSG00000105618.9875.70610597.587300.551203.196202.00980K562TRA2A
PRPF31ENSG00000105618.92657.229103281.59580-0.304502.799501.38990K562UBE2L3
PRPF31ENSG00000105618.91856.626302107.82660-0.183101.968101.35540K562UPF1
PRPF31ENSG00000105618.91363.241101803.61430-0.403904.434203.31580K562WDR3
PRPF31ENSG00000105618.91665.535102124.29020-0.351003.334402.37580K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PRPF31 is not available on ENCORE database.





15 RBPs can affect the splicing of PRPF31 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPRPF31ENSG00000105618.9chr19+5462565654625717546252385462532254625875546259730.130000.000080.00264includedK562SF3B4
SEPRPF31ENSG00000105618.9chr19+5462554054625717546252385462532254625875546259730.116000.000000.00004includedK562AKAP8L
SEPRPF31ENSG00000105618.9chr19+5462563854625717546252385462532254625875546259730.054000.000280.00935includedHepG2HNRNPK
SEPRPF31ENSG00000105618.9chr19+5462561054625717546252385462532254625875546259730.139000.000000.00001includedK562PUS1
SEPRPF31ENSG00000105618.9chr19+546316795463175254631447546315755463243154632483-0.105000.000000.00004excludedHepG2SF3A3
SEPRPF31ENSG00000105618.9chr19+5462554054625717546252385462532254625875546259730.084000.000000.00035includedK562HNRNPUL1
SEPRPF31ENSG00000105618.9chr19+5462554054625717546252385462532254625875546259730.087000.000010.00086includedK562UTP18
SEPRPF31ENSG00000105618.9chr19+5462565654625717546252385462532254625875546259730.084000.000010.00063includedK562AGGF1
SEPRPF31ENSG00000105618.9chr19+5462554054625717546252385462532254625875546259730.078000.000080.00619includedK562HNRNPK
A3SSPRPF31ENSG00000105618.9chr19+5463164354631752546316795463175254631447546315750.077000.000060.00923longerHepG2RBM22
RIPRPF31ENSG00000105618.9chr19+5463243154632745546324315463256054632646546327450.307000.000000.00000includedK562PUS1
RIPRPF31ENSG00000105618.9chr19+5463243154632745546324315463256054632646546327450.129000.006300.05984includedHepG2SF3A3
RIPRPF31ENSG00000105618.9chr19+5463144754631752546314475463157554631679546317520.075000.000010.00027includedHepG2SF3A3
RIPRPF31ENSG00000105618.9chr19+5463243154632745546324315463256054632646546327450.160000.000480.01412includedK562HNRNPC
RIPRPF31ENSG00000105618.9chr19+5463243154632745546324315463256054632646546327450.318000.001300.01118includedHepG2U2AF2
RIPRPF31ENSG00000105618.9chr19+5463243154632745546324315463256054632646546327450.160000.000350.00550includedHepG2QKI
RIPRPF31ENSG00000105618.9chr19+5463243154632745546324315463256054632646546327450.122000.003500.03594includedK562RBM15
RIPRPF31ENSG00000105618.9chr19+5463243154632745546324315463256054632646546327450.131000.001490.03172includedHepG2KHSRP
RIPRPF31ENSG00000105618.9chr19+5463243154632745546324315463256054632646546327450.127000.001630.01388includedHepG2SF3B4
RIPRPF31ENSG00000105618.9chr19+5463144754631752546314475463157554631679546317520.078000.000290.00465includedHepG2RBM22
RIPRPF31ENSG00000105618.9chr19+5463243154632745546324315463256054632646546327450.165000.000030.00060includedHepG2HNRNPK
RIPRPF31ENSG00000105618.9chr19+5463243154632745546324315463256054632646546327450.149000.010250.09071includedK562UTP18
RIPRPF31ENSG00000105618.9chr19+5463243154632745546324315463256054632646546327450.179000.000000.00001includedK562AQR
RIPRPF31ENSG00000105618.9chr19+5463144754631752546314475463157554631679546317520.151000.000000.00000includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PRPF31 is not avaliable on ENCORE database.