PREP

General Information

Gene Name       : PREP
Gene ID             : ENSG00000085377.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PREP)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PREPENSG00000085377.1317.5516.1916.87ENCSR000AEF
HepG2PREPENSG00000085377.1327.7330.6029.16ENCSR985KAT
K562PREPENSG00000085377.1340.9540.9140.93ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PREP is not avaliable on ENCORE database.



Proteins bound to RNA
  • PREP RNA is bound by 11 proteins.  







eCLIP assay for PREP is not avaliable on ENCORE database.





11 proteins are bound to PREP RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6105725679105725773-3'-UTR,intron-Distal5.2026123.66195K562PUM2
chr6105725620105725669-3'-UTR,intron-Distal6.007267.49093K562PABPC4
chr6105725780105725850-3'-UTR,intron-Distal3.454784.46957K562TIA1
chr6105850787105850953-5'-UTR,intron-Distal3.855885.82148K562DDX3X
chr6105776803105776856-CDS,intron-Distal3.012753.50044K562YBX3
chr6105821275105821365-CDS,intron-Distal4.339694.55369K562LIN28B
chr6105816776105816860-CDS,intron-Distal,intron-Proximal4.755517.60539K562LIN28B
chr6105771499105771562-CDS,intron-Distal,intron-Proximal4.956164.75655HepG2PRPF8
chr6105821243105821311-CDS,intron-Distal,intron-Proximal4.248794.48692K562YBX3
chr6105733363105733436-CDS,intron-Distal3.045076.48212K562TIA1
chr6105771459105771554-CDS,intron-Distal,intron-Proximal3.097705.17453K562PRPF8
chr6105756849105756923-intron-Distal5.238327.48549HepG2RBFOX2
chr6105744876105744937-intron-Distal3.572793.60408HepG2XPO5
chr6105764404105764519-intron-Distal3.701343.16095HepG2U2AF2
chr6105777849105777908-intron-Distal3.972103.03891HepG2PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PREP is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PREP is not available on ENCORE database.

  • 107 RBPs can affect the levels of PREP.  








The Knockdown/knockout RNA-Seq assay for PREP is not available on ENCORE database.





107 RBPs can affect the gene expression of PREP :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PREPENSG00000085377.9728.79170982.66850-0.431202.351501.48140HepG2ABCF1
PREPENSG00000085377.9560.18750865.45880-0.627605.852704.47440HepG2ADAR
PREPENSG00000085377.91703.036301088.582900.645605.860005.11910HepG2AKAP1
PREPENSG00000085377.9555.58950900.71600-0.697106.452205.27570HepG2ASCC1
PREPENSG00000085377.9592.87200773.49750-0.383702.360201.53230HepG2BCLAF1
PREPENSG00000085377.9617.50650855.74060-0.470703.344602.49980HepG2CIRBP
PREPENSG00000085377.9708.26160871.49750-0.299203.072102.19610HepG2DDX19B
PREPENSG00000085377.9564.02370872.03830-0.628605.930104.50400HepG2DDX5
PREPENSG00000085377.9535.11060901.54200-0.7526012.3539011.13520HepG2DKC1
PREPENSG00000085377.9723.38070871.46490-0.268702.059101.44260HepG2DNAJC21
PREPENSG00000085377.9555.60950863.79300-0.6366010.980509.77840HepG2DNAJC2
PREPENSG00000085377.9568.01510748.78740-0.398602.337001.48770HepG2EEF2
PREPENSG00000085377.9560.75420861.13480-0.618905.078604.28890HepG2EIF2S1
PREPENSG00000085377.9735.88640951.66750-0.371002.117301.55520HepG2EIF4A3
PREPENSG00000085377.91199.905301474.26240-0.297103.216902.32850HepG2EIF4G1
PREPENSG00000085377.91038.084901412.23610-0.444103.884302.92920HepG2EIF4G2
PREPENSG00000085377.91115.437401554.96570-0.479308.414807.46480HepG2ETF1
PREPENSG00000085377.9378.49620543.27570-0.521404.232902.75960HepG2FAM120A
PREPENSG00000085377.9374.89620758.13000-1.0160014.4742012.24520HepG2FASTKD2
PREPENSG00000085377.9656.01920890.70450-0.441202.839802.16620HepG2G3BP1
PREPENSG00000085377.9653.57490945.57150-0.532804.298003.17670HepG2G3BP2
PREPENSG00000085377.9572.93900841.81280-0.555104.041603.28060HepG2GPKOW
PREPENSG00000085377.9555.04410879.81400-0.664606.956206.00100HepG2HNRNPA1
PREPENSG00000085377.9762.15480978.63820-0.360702.564301.89480HepG2HNRNPC
PREPENSG00000085377.9690.993201037.87410-0.586908.977207.77920HepG2HNRNPF
PREPENSG00000085377.9679.91130901.87350-0.407602.830902.12330HepG2HNRNPK
PREPENSG00000085377.9961.380401361.14180-0.501606.992005.96550HepG2HNRNPL
PREPENSG00000085377.9602.16950803.36360-0.415902.598701.98520HepG2HNRNPLL
PREPENSG00000085377.9706.79120972.16740-0.459906.100005.23000HepG2HNRNPU
PREPENSG00000085377.9655.494801022.01050-0.640808.240507.05240HepG2IGF2BP1
PREPENSG00000085377.9601.59320905.38860-0.589704.889304.01500HepG2IGF2BP2
PREPENSG00000085377.9765.93490993.03550-0.374604.819503.87450HepG2ILF2
PREPENSG00000085377.9699.95780861.37680-0.299403.034001.96990HepG2KIF1C
PREPENSG00000085377.9739.44950960.49050-0.377302.341301.73600HepG2MAGOH
PREPENSG00000085377.9563.49010819.47460-0.540302.737701.77500HepG2MTPAP
PREPENSG00000085377.91077.273601481.72110-0.459905.798004.69980HepG2NOL12
PREPENSG00000085377.9537.59000712.38470-0.406202.565101.84320HepG2NSUN2
PREPENSG00000085377.9810.01470962.26960-0.248502.058501.31870HepG2PARN
PREPENSG00000085377.9639.79900867.09430-0.438604.597403.67040HepG2PPIL4
PREPENSG00000085377.9659.93770930.70810-0.496002.558001.38200HepG2PRPF6
PREPENSG00000085377.9850.747101414.45550-0.7334010.571709.50720HepG2PUF60
PREPENSG00000085377.91126.769301501.53390-0.414207.324506.45500HepG2PUM1
PREPENSG00000085377.9854.957601500.42040-0.8114014.9233013.44310HepG2PUM2
PREPENSG00000085377.9757.15080959.81760-0.342203.809103.10990HepG2PUS1
PREPENSG00000085377.9730.673001104.86070-0.596607.688306.36100HepG2RBM15
PREPENSG00000085377.9779.599201022.08510-0.390702.982201.95060HepG2RBM27
PREPENSG00000085377.9559.677201118.03180-0.9983015.4238014.06250HepG2RPLP0
PREPENSG00000085377.9443.72950839.38780-0.919707.151205.68600HepG2RPS10
PREPENSG00000085377.9422.94720591.46570-0.483803.645002.94910HepG2RPS19
PREPENSG00000085377.9680.86370942.60330-0.469303.859202.91890HepG2RPS2
PREPENSG00000085377.9680.15070865.75350-0.348103.623802.90360HepG2SAFB2
PREPENSG00000085377.9596.23110795.13210-0.415302.985402.25260HepG2SF3B1
PREPENSG00000085377.91029.828701356.29770-0.397306.002505.03130HepG2SLBP
PREPENSG00000085377.9588.35940884.73790-0.588603.330802.46980HepG2SNRNP70
PREPENSG00000085377.9662.374601467.89120-1.1480038.9331037.62200HepG2SRFBP1
PREPENSG00000085377.91462.98650980.729700.5769010.625709.83120HepG2SRSF1
PREPENSG00000085377.91061.282101396.60110-0.396105.313204.48670HepG2SRSF5
PREPENSG00000085377.9700.407201019.67400-0.541807.698806.63300HepG2SRSF7
PREPENSG00000085377.9535.98560797.88290-0.574007.693206.85740HepG2SRSF9
PREPENSG00000085377.9791.708401274.44410-0.6868014.1884013.20790HepG2SSB
PREPENSG00000085377.9463.71520662.88780-0.515502.977701.70020HepG2STAU1
PREPENSG00000085377.9315.03140453.89720-0.526902.806401.69720HepG2STIP1
PREPENSG00000085377.91313.108601588.29250-0.274503.275102.61010HepG2SUCLG1
PREPENSG00000085377.9403.13980871.33170-1.1119013.4164012.11170HepG2SUPV3L1
PREPENSG00000085377.9602.81590783.21050-0.377702.473301.78200HepG2TARDBP
PREPENSG00000085377.9302.32790944.61310-1.6436040.8870039.38250HepG2TIAL1
PREPENSG00000085377.9599.70410857.98350-0.516702.780401.30780HepG2TRA2A
PREPENSG00000085377.9934.250601381.90710-0.564806.914105.43490HepG2TUFM
PREPENSG00000085377.9588.13130847.73750-0.527507.019705.99130HepG2UPF1
PREPENSG00000085377.9556.18620857.73200-0.625005.584504.56650HepG2XRN2
PREPENSG00000085377.9419.78390763.44030-0.8629015.7309014.34440HepG2ZC3H8
PREPENSG00000085377.92068.272501501.581300.461808.720107.78760K562AGGF1
PREPENSG00000085377.91883.314801562.467800.269302.098801.52720K562AKAP8L
PREPENSG00000085377.91193.722302390.98810-1.0021018.6303017.27510K562AQR
PREPENSG00000085377.91996.864001639.413200.284503.201402.21370K562ATP5C1
PREPENSG00000085377.91176.497301497.68650-0.348204.604403.34850K562BCLAF1
PREPENSG00000085377.9756.677701095.89710-0.534404.740203.58530K562BOP1
PREPENSG00000085377.9629.30300827.97930-0.395802.741201.69420K562CCAR1
PREPENSG00000085377.91387.652301794.45770-0.370903.887002.45960K562CCDC124
PREPENSG00000085377.91415.013802111.57800-0.577503.269202.09830K562CNOT7
PREPENSG00000085377.9776.988701165.29030-0.584705.921604.77820K562CPSF6
PREPENSG00000085377.92966.786803780.87720-0.349804.533103.27520K562CELF1
PREPENSG00000085377.91888.967002210.72510-0.226902.547601.91910K562DDX47
PREPENSG00000085377.91106.960201395.58110-0.334303.574702.03590K562DDX6
PREPENSG00000085377.92300.169001681.299600.452107.766706.16570K562DKC1
PREPENSG00000085377.9945.729901321.63560-0.482803.198001.81340K562EEF2
PREPENSG00000085377.9962.967801276.98260-0.407203.147902.17030K562EFTUD2
PREPENSG00000085377.91161.358401511.96460-0.380605.115803.44270K562EIF2S1
PREPENSG00000085377.91397.201201865.59920-0.417106.166905.15650K562EIF2S2
PREPENSG00000085377.9539.92790842.22170-0.641403.052001.99010K562EIF3A
PREPENSG00000085377.92332.911903074.94060-0.398406.400404.99300K562EIF4G2
PREPENSG00000085377.91015.508601284.84950-0.339402.947001.63770K562EXOSC5
PREPENSG00000085377.9889.977701217.92620-0.452604.455302.38260K562FASTKD2
PREPENSG00000085377.9764.304501185.58310-0.633406.781305.42010K562FMR1
PREPENSG00000085377.9713.576201004.85730-0.493903.744502.66690K562FTO
PREPENSG00000085377.9686.528501112.59530-0.696507.390006.09050K562GPKOW
PREPENSG00000085377.91743.450502486.11130-0.511906.985505.77640K562GRSF1
PREPENSG00000085377.91470.666501835.13800-0.319403.031701.90550K562HNRNPA1
PREPENSG00000085377.9729.948401394.24160-0.9336016.5308015.14970K562HNRNPC
PREPENSG00000085377.91232.429001626.26810-0.400103.210901.86980K562HNRNPK
PREPENSG00000085377.91527.673502032.16990-0.411705.850204.53860K562HNRNPU
PREPENSG00000085377.91774.520002196.96270-0.308102.413301.66660K562HSPD1
PREPENSG00000085377.92076.847301658.153400.324702.898702.05180K562KIF1C
PREPENSG00000085377.9623.93540949.93950-0.606404.023302.88070K562KRR1
PREPENSG00000085377.91412.999001707.79800-0.273402.319901.48130K562MATR3
PREPENSG00000085377.92683.905501857.552800.530807.987006.27980K562MBNL1
PREPENSG00000085377.9783.667701086.00460-0.470704.219003.12280K562METAP2
PREPENSG00000085377.92420.630403277.57950-0.437204.544303.09370K562MSI2
PREPENSG00000085377.91291.642801750.64760-0.438707.563206.28350K562MTPAP
PREPENSG00000085377.91983.709701302.011300.607403.728802.66640K562NAA15
PREPENSG00000085377.91408.249701945.03570-0.4659011.365409.99480K562NSUN2
PREPENSG00000085377.91429.827502028.60720-0.504602.961201.67940K562PABPC1
PREPENSG00000085377.92278.773503354.99120-0.558107.999006.60370K562PUF60
PREPENSG00000085377.92553.805003496.48150-0.453308.534506.82100K562PUM2
PREPENSG00000085377.92428.400201549.507900.648108.690207.77700K562PUS1
PREPENSG00000085377.91929.320201509.788100.353604.373003.64540K562RBM15
PREPENSG00000085377.91275.072001594.23970-0.322302.545101.74260K562RBM22
PREPENSG00000085377.91370.226601919.38920-0.486208.120506.78140K562SF3A3
PREPENSG00000085377.9707.176401058.00900-0.581204.650003.36860K562SF3B1
PREPENSG00000085377.91096.354601421.51920-0.374704.011502.97460K562SF3B4
PREPENSG00000085377.92131.506401629.908300.387004.340903.45910K562SRSF1
PREPENSG00000085377.9784.78310982.11450-0.323602.300501.35650K562SRSF4
PREPENSG00000085377.9707.841201203.20440-0.765407.984706.20410K562SUPV3L1
PREPENSG00000085377.91155.959401649.57320-0.513005.173104.19030K562TARDBP
PREPENSG00000085377.9561.058001202.37230-1.0997016.0784013.67580K562TIAL1
PREPENSG00000085377.91834.286302193.07630-0.257703.395901.97910K562TROVE2
PREPENSG00000085377.91067.140901368.55990-0.358903.567702.65490K562U2AF2
PREPENSG00000085377.9883.824001273.41840-0.526904.746603.37270K562UCHL5
PREPENSG00000085377.91493.732002062.36980-0.465409.171307.95780K562UPF1
PREPENSG00000085377.91315.227401764.69290-0.424104.706303.55140K562WDR3
PREPENSG00000085377.91414.407201835.15670-0.375706.372705.13900K562WDR43
PREPENSG00000085377.9974.375601296.65610-0.412203.147101.82760K562XRN2
PREPENSG00000085377.91782.581402693.47420-0.595508.580906.93560K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PREP is not available on ENCORE database.





2 RBPs can affect the splicing of PREP :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPREPENSG00000085377.9chr6-1057708801057709861057366321057367691057715391057716430.203000.000010.00014includedK562AQR
SEPREPENSG00000085377.9chr6-105733360105733455105730325105730457105736632105736769-0.154000.000000.00000excludedK562AQR
SEPREPENSG00000085377.9chr6-105781188105781380105776703105776901105800846105800952-0.052000.000630.05745excludedHepG2SRSF7
A3SSPREPENSG00000085377.9chr6-1057767031057769261057767031057769011057811881057813800.175000.000000.00000longerK562AQR
A3SSPREPENSG00000085377.9chr6-1057811881057814341057811881057813801058008461058009520.052000.000000.00000longerK562AQR
A3SSPREPENSG00000085377.9chr6-1057708801057710421057708801057709861057715391057716430.121000.010600.05553longerK562AQR
A3SSPREPENSG00000085377.9chr6-1057296201057298261057296201057297771057303251057305140.072000.000000.00001longerK562AQR
A3SSPREPENSG00000085377.9chr6-1058239991058242271058239991058241301058252601058253940.053000.000000.00002longerK562AQR
A3SSPREPENSG00000085377.9chr6-1057333601057334801057333601057334551057366321057367690.064000.000170.00139longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PREP is not avaliable on ENCORE database.