POLRMT

General Information

Gene Name       : POLRMT
Gene ID             : ENSG00000099821.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: POLRMT)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878POLRMTENSG00000099821.134.6120.9612.79ENCSR000AEF
HepG2POLRMTENSG00000099821.13113.2945.8679.58ENCSR985KAT
K562POLRMTENSG00000099821.1371.9148.3060.10ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for POLRMT is not avaliable on ENCORE database.



Proteins bound to RNA
  • POLRMT RNA is bound by 24 proteins.  







eCLIP assay for POLRMT is not avaliable on ENCORE database.





24 proteins are bound to POLRMT RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr19617234617273-3'-UTR,intron-Distal,intron-Proximal4.838517.06234K562PUM2
chr19630063630108-3'-UTR,CDS,intron-Distal,intron-Proximal3.974463.03355K562METAP2
chr19630106630169-3'-UTR,CDS,intron-Distal,intron-Proximal4.280963.96931HepG2G3BP1
chr19632800632858-5'-UTR,CDS,intron-Distal,intron-Proximal4.145218.98325HepG2PPIG
chr19633453633520-5'-UTR,CDS,intron-Distal,intron-Proximal3.726905.08370HepG2DDX3X
chr19617858617988-CDS,intron-Distal,intron-Proximal3.138906.85237K562RBFOX2
chr19622949623053-CDS,intron-Distal,intron-Proximal4.108678.48964K562SF3B4
chr19618441618519-CDS,intron-Distal,intron-Proximal4.5305916.25866HepG2PRPF8
chr19621184621236-CDS,intron-Distal4.549934.41602K562FXR2
chr19619918619960-CDS,intron-Distal,intron-Proximal3.244555.24055HepG2PRPF8
chr19617601617667-CDS,intron-Distal,intron-Proximal3.203567.21322K562AQR
chr19622825622871-CDS,intron-Distal,intron-Proximal5.515525.93845K562DDX24
chr19617639617696-CDS,intron-Distal,intron-Proximal5.4558211.57871K562BUD13
chr19617863617951-CDS,intron-Distal,intron-Proximal3.966016.57821HepG2AQR
chr19622819622868-CDS,intron-Distal,intron-Proximal3.129418.52439HepG2PPIG
chr19618395618494-CDS,intron-Distal,intron-Proximal4.2987016.05612K562AQR
chr19621057621095-CDS,intron-Distal,intron-Proximal4.116745.24452HepG2PPIG
chr19617856617904-CDS,intron-Distal,intron-Proximal4.067143.98315HepG2SF3B4
chr19623368623459-CDS,intron-Distal,intron-Proximal4.964706.80961HepG2EFTUD2
chr19620077620203-CDS,intron-Distal,intron-Proximal3.220383.23179HepG2RBFOX2
chr19622583622600-CDS,intron-Distal3.620223.32039HepG2PPIG
chr19617437617473-CDS,intron-Distal,intron-Proximal3.625574.44431K562BUD13
chr19623416623458-CDS,intron-Distal,intron-Proximal3.633026.46344HepG2PRPF8
chr19617868617912-CDS,intron-Distal,intron-Proximal3.611519.39957HepG2PRPF8
chr19617568617615-CDS,intron-Distal,intron-Proximal4.3844111.01413HepG2PPIG
chr19617829617920-CDS,intron-Distal,intron-Proximal4.0644218.55857K562AQR
chr19621314621377-CDS,intron-Distal4.741595.42280K562FXR2
chr19617636617682-CDS,intron-Distal,intron-Proximal4.084079.31583K562SF3B4
chr19617419617470-CDS,intron-Distal4.6584910.14097HepG2PPIG
chr19621060621148-CDS,intron-Distal4.243205.66107K562FXR2
chr19619569619587-CDS,intron-Distal,intron-Proximal3.619066.65114HepG2PRPF8
chr19617859617924-CDS,intron-Distal,intron-Proximal4.689359.04180K562SF3B4
chr19633424633513-CDS,intron-Distal,intron-Proximal5.678716.26070K562DDX3X
chr19629503629543-CDS,intron-Distal,intron-Proximal5.101967.70650HepG2PRPF8
chr19622056622151-CDS,intron-Distal,intron-Proximal4.8811420.50766HepG2PRPF8
chr19617470617481-CDS,intron-Distal,intron-Proximal5.698998.85296HepG2PPIG
chr19630307630382-intron-Distal3.300403.57928K562GTF2F1
chr19625350625411-intron-Distal,intron-Proximal5.757238.11845HepG2SF3A3
chr19622506622559-intron-Distal,intron-Proximal5.208177.29007HepG2RBM22
chr19620097620156-intron-Distal,intron-Proximal4.103813.01266HepG2SF3B4
chr19617934618001-intron-Distal,intron-Proximal4.661966.10679HepG2RBFOX2
chr19618620618698-intron-Distal,intron-Proximal4.671314.97857HepG2AQR
chr19619549619569-intron-Distal,intron-Proximal4.033405.64484HepG2PRPF8
chr19622987623033-intron-Distal,intron-Proximal4.801747.19196HepG2SF3B4
chr19618354618441-intron-Distal,intron-Proximal3.291716.25850HepG2PRPF8
chr19627877627928-intron-Distal3.750883.24590HepG2ILF3
chr19618031618083-intron-Distal,intron-Proximal5.157637.81156K562BUD13
chr19622515622575-intron-Distal,intron-Proximal4.147717.87148HepG2PRPF8
chr19617664617743-intron-Distal,intron-Proximal3.956983.20724K562SMNDC1
chr19622992623044-intron-Distal,intron-Proximal5.849368.30797HepG2SF3A3
chr19617662617718-intron-Distal,intron-Proximal3.232436.09777K562PRPF8
chr19617943617976-intron-Distal,intron-Proximal3.763828.17589HepG2PRPF8
chr19630465630557-intron-Distal,intron-Proximal4.364484.57620HepG2PRPF4
chr19617906617983-intron-Distal,intron-Proximal4.446779.73538K562DDX24
chr19617909617978-intron-Distal,intron-Proximal3.604248.44995K562PRPF8
chr19618302618363-intron-Distal4.4011110.93035K562AQR
chr19620761620872-intron-Distal4.683225.31936HepG2HNRNPK
chr19621849621908-intron-Distal,intron-Proximal4.066828.03271HepG2SF3A3
chr19617656617714-intron-Distal,intron-Proximal4.809374.62947HepG2AQR
chr19618026618133-intron-Distal,intron-Proximal4.5650113.33851K562DDX24
chr19617682617712-intron-Distal,intron-Proximal3.700717.52070K562SF3B4
chr19618263618341-intron-Distal3.7060510.41546K562BUD13
chr19617667617739-intron-Distal,intron-Proximal4.6996324.22695K562AQR
chr19632260632351-intron-Distal3.870683.57432K562NONO
chr19618101618125-intron-Distal3.844675.34978HepG2PRPF8
chr19617663617715-intron-Distal,intron-Proximal5.345625.58036HepG2EFTUD2
chr19617920617967-intron-Distal,intron-Proximal3.358188.69914K562AQR
chr19622503622556-intron-Distal,intron-Proximal5.738115.99517HepG2EFTUD2
chr19625348625403-intron-Distal,intron-Proximal5.254759.67053HepG2SF3B4
chr19618376618400-intron-Distal,intron-Proximal5.494735.10740K562DDX24
chr19618083618151-intron-Distal,intron-Proximal3.246436.76988K562BUD13
chr19618278618329-intron-Distal4.033413.91585HepG2PRPF4
chr19617696617764-intron-Distal,intron-Proximal3.254407.34413K562BUD13
chr19618341618433-intron-Distal,intron-Proximal5.0818315.20849K562BUD13
chr19630266630369-intron-Distal,intron-Proximal4.310894.72743K562NONO
chr19630284630366-intron-Distal3.200273.15535K562EWSR1
chr19617901617978-intron-Distal,intron-Proximal3.074696.72480K562BUD13
chr19617878617928-intron-Distal,intron-Proximal3.808094.83721K562EFTUD2
chr19623051623113-intron-Distal,intron-Proximal3.318674.29246HepG2SF3B4
chr19620316620365-intron-Distal,intron-Proximal5.688278.88118K562AQR
chr19617903618000-intron-Distal,intron-Proximal3.615383.85148K562GTF2F1
chr19617943617973-intron-Distal,intron-Proximal4.656367.37772HepG2EFTUD2
chr19618353618395-intron-Distal,intron-Proximal3.423434.98422K562PRPF8
chr19620658620846-intron-Distal4.5701812.68579HepG2DDX59
chr19617697617777-intron-Distal,intron-Proximal3.403999.25476HepG2PRPF8
chr19620321620364-intron-Distal,intron-Proximal4.8342913.44390HepG2PRPF8
chr19617688617720-intron-Distal,intron-Proximal3.117363.12941K562UCHL5
chr19620687620761-intron-Distal3.941803.06084HepG2HNRNPK
chr19617907617987-intron-Distal,intron-Proximal3.859703.03048HepG2GTF2F1
chr19618271618365-intron-Distal3.570384.39249K562RBFOX2
chr19618090618159-intron-Distal3.180695.62051HepG2PRPF4
chr19619914619952-intron-Distal,intron-Proximal4.992115.65342K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for POLRMT is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for POLRMT is not available on ENCORE database.

  • 101 RBPs can affect the levels of POLRMT.  








The Knockdown/knockout RNA-Seq assay for POLRMT is not available on ENCORE database.





101 RBPs can affect the gene expression of POLRMT :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
POLRMTENSG00000099821.9361.68280523.54180-0.533602.800902.02490HepG2CALR
POLRMTENSG00000099821.9406.11840585.32960-0.527301.896801.31600HepG2CPSF6
POLRMTENSG00000099821.91127.62520878.869000.359502.517201.46240HepG2CPSF7
POLRMTENSG00000099821.9461.78670315.867200.547804.457003.16460HepG2YBX3
POLRMTENSG00000099821.9868.72220573.719600.598407.931906.94930HepG2CELF1
POLRMTENSG00000099821.9267.83250427.84100-0.675703.260102.26550HepG2DDX24
POLRMTENSG00000099821.9523.94430310.139500.756402.165401.53470HepG2DNAJC21
POLRMTENSG00000099821.9522.22080307.427600.7643010.333709.16970HepG2DNAJC2
POLRMTENSG00000099821.9722.36340506.923000.510903.345702.33950HepG2EEF2
POLRMTENSG00000099821.91513.256601824.75140-0.270002.277901.72380HepG2ETF1
POLRMTENSG00000099821.9491.63240367.837900.418402.761001.59560HepG2FAM120A
POLRMTENSG00000099821.9591.20470900.18930-0.606606.502205.32630HepG2FUBP3
POLRMTENSG00000099821.9691.90130375.414100.882002.884401.48210HepG2HNRNPA0
POLRMTENSG00000099821.9954.75660685.511600.477906.337505.31310HepG2HNRNPF
POLRMTENSG00000099821.91487.89310942.096300.659202.757702.06210HepG2HNRNPK
POLRMTENSG00000099821.9756.84960561.952100.429504.776103.90810HepG2HNRNPL
POLRMTENSG00000099821.9618.13970345.983700.837105.420004.59320HepG2HNRNPU
POLRMTENSG00000099821.9898.78930675.037900.412902.799702.07150HepG2IGF2BP1
POLRMTENSG00000099821.91960.857701008.038300.959805.011504.18470HepG2MATR3
POLRMTENSG00000099821.9560.67370732.40360-0.385502.999601.73570HepG2NAA15
POLRMTENSG00000099821.9825.82320492.728900.744902.841701.73400HepG2NONO
POLRMTENSG00000099821.9884.15390405.143701.125803.948302.87510HepG2PABPC1
POLRMTENSG00000099821.9574.76600308.588200.8972012.1523010.67550HepG2PPIL4
POLRMTENSG00000099821.91304.15110583.933801.1591023.1647021.66360HepG2PUF60
POLRMTENSG00000099821.91171.90610619.868000.9187025.3014023.87540HepG2PUM1
POLRMTENSG00000099821.9977.57920619.417400.658202.222401.61870HepG2PUM2
POLRMTENSG00000099821.9898.371501525.12350-0.7635012.4525011.51410HepG2RBM22
POLRMTENSG00000099821.9784.20310495.524600.662203.438202.32750HepG2RBM27
POLRMTENSG00000099821.9667.61320402.391100.730302.608001.58040HepG2RCC2
POLRMTENSG00000099821.9715.00160456.946600.645803.393802.50820HepG2RPS2
POLRMTENSG00000099821.9681.46210308.108501.145106.732405.79350HepG2SAFB2
POLRMTENSG00000099821.91682.701401101.859500.610704.792303.88990HepG2SF3A3
POLRMTENSG00000099821.9951.87560559.894300.7655015.1982013.79270HepG2SLBP
POLRMTENSG00000099821.9579.60060359.297700.689809.108808.04940HepG2SMN1
POLRMTENSG00000099821.9403.13060697.24000-0.790403.708202.79880HepG2SNRNP70
POLRMTENSG00000099821.91424.096301722.51600-0.274502.300501.83020HepG2SRFBP1
POLRMTENSG00000099821.9734.150101059.01780-0.528607.219606.53920HepG2SRSF1
POLRMTENSG00000099821.91125.31590576.545400.9647022.6200021.06990HepG2SRSF5
POLRMTENSG00000099821.9884.74930673.476300.393504.274903.43830HepG2SRSF7
POLRMTENSG00000099821.9691.46320861.58580-0.317303.020402.44910HepG2SRSF9
POLRMTENSG00000099821.91194.995301495.45590-0.323602.371101.88870HepG2SSB
POLRMTENSG00000099821.9756.42270387.914800.963403.876702.55150HepG2STIP1
POLRMTENSG00000099821.91053.76110655.694500.6844013.0842011.89760HepG2SUCLG1
POLRMTENSG00000099821.9374.03890951.94570-1.3477018.5697017.30330HepG2TAF15
POLRMTENSG00000099821.9621.40010874.64560-0.493203.900802.91720HepG2TIA1
POLRMTENSG00000099821.9566.86710336.154400.753807.932407.16520HepG2TIAL1
POLRMTENSG00000099821.9675.66300339.195200.9941017.4884016.23050HepG2TRIM56
POLRMTENSG00000099821.9907.21350570.472900.669206.348104.93820HepG2TUFM
POLRMTENSG00000099821.91102.30780603.832800.868202.300501.54290HepG2UBE2L3
POLRMTENSG00000099821.9504.27510315.170300.678002.724901.97070HepG2UCHL5
POLRMTENSG00000099821.91334.61810943.430100.500303.737703.05790HepG2UTP3
POLRMTENSG00000099821.9729.20620399.187200.869202.920801.78830HepG2XPO5
POLRMTENSG00000099821.9809.72830525.330300.624102.061001.42700HepG2XRN2
POLRMTENSG00000099821.9527.61930771.75280-0.548607.301506.29600HepG2ZC3H8
POLRMTENSG00000099821.92584.319701518.742500.7668024.2751022.70890K562AGGF1
POLRMTENSG00000099821.91633.324901276.107100.356004.511802.54750K562AKAP1
POLRMTENSG00000099821.92211.554801668.928900.406003.663002.49480K562AKAP8
POLRMTENSG00000099821.92518.071601580.335300.672008.610707.39390K562AKAP8L
POLRMTENSG00000099821.91234.624002063.65280-0.7411010.682409.64100K562AQR
POLRMTENSG00000099821.92444.893601658.180200.5601011.152309.15130K562ATP5C1
POLRMTENSG00000099821.91084.53500860.861200.333102.976701.60590K562BCCIP
POLRMTENSG00000099821.91356.94510831.972900.7057011.125609.19490K562BCLAF1
POLRMTENSG00000099821.92100.934301595.815900.396603.813202.50650K562CPEB4
POLRMTENSG00000099821.91159.17130631.175600.876905.748304.14240K562CSTF2
POLRMTENSG00000099821.91024.95210729.375300.490705.144403.33050K562DDX27
POLRMTENSG00000099821.91664.453701292.985900.364202.966901.88590K562DDX3X
POLRMTENSG00000099821.91963.033901650.919200.249702.907602.23970K562DDX47
POLRMTENSG00000099821.91756.944001310.904300.422403.144701.72580K562DDX6
POLRMTENSG00000099821.92316.743601700.460600.446107.788206.18510K562DKC1
POLRMTENSG00000099821.9511.88060320.953300.673304.049003.09610K562EIF3G
POLRMTENSG00000099821.91495.751001216.477900.298102.943301.74200K562EIF4B
POLRMTENSG00000099821.91056.11280845.874700.320102.254301.48840K562FIP1L1
POLRMTENSG00000099821.9410.72380538.62430-0.391102.240701.46810K562FMR1
POLRMTENSG00000099821.934.97870210.38610-2.588506.280905.11800K562G3BP2
POLRMTENSG00000099821.9697.41830897.61190-0.364102.257201.71030K562HNRNPC
POLRMTENSG00000099821.91326.35500515.303801.363904.033102.69670K562IGF2BP2
POLRMTENSG00000099821.9871.36200523.970400.733703.499602.12010K562IGF2BP3
POLRMTENSG00000099821.9295.67030431.56130-0.545602.304901.46130K562KRR1
POLRMTENSG00000099821.91063.73530541.159900.974908.917707.36150K562MAGOH
POLRMTENSG00000099821.92017.861501605.419100.329803.127101.96600K562MAK16
POLRMTENSG00000099821.9838.62160540.000600.635003.613602.54740K562MATR3
POLRMTENSG00000099821.9998.659801348.91330-0.433702.788901.55450K562NCBP2
POLRMTENSG00000099821.91191.05000884.214800.429703.049701.53240K562NUSAP1
POLRMTENSG00000099821.9974.374401356.67410-0.477502.485901.33080K562PABPC1
POLRMTENSG00000099821.9734.21650529.172900.472402.816601.45450K562PCBP1
POLRMTENSG00000099821.9684.31340481.424500.507202.163701.30290K562PCBP2
POLRMTENSG00000099821.9982.871901613.79580-0.715402.956402.09680K562PCBP3
POLRMTENSG00000099821.9850.360401237.78040-0.541606.834605.58550K562POLR2G
POLRMTENSG00000099821.91416.91400960.327900.561106.135904.83350K562PPIG
POLRMTENSG00000099821.91074.93970804.881000.417303.353402.34420K562PSIP1
POLRMTENSG00000099821.91200.69720525.800901.1912015.1574013.66690K562PTBP1
POLRMTENSG00000099821.92011.577102743.28950-0.447603.682902.43940K562PUM1
POLRMTENSG00000099821.92033.996401567.152600.376103.412602.81880K562PUS1
POLRMTENSG00000099821.92257.352501527.042300.5638010.557709.42420K562RBM15
POLRMTENSG00000099821.9927.57350734.724600.336202.187101.30970K562RCC2
POLRMTENSG00000099821.9746.265101259.43950-0.755005.369103.06030K562RPS3A
POLRMTENSG00000099821.9793.991201140.36610-0.522304.914702.97070K562SDAD1
POLRMTENSG00000099821.9453.37840218.400101.053606.772605.39800K562SF3B4
POLRMTENSG00000099821.9991.90380515.505600.9441015.0065013.35470K562SRSF1
POLRMTENSG00000099821.9968.47370554.887100.8034010.272808.12040K562SRSF4
POLRMTENSG00000099821.91016.99400486.968501.062306.815205.05820K562SRSF5
POLRMTENSG00000099821.91054.58900521.627501.015508.266206.95840K562TARDBP
POLRMTENSG00000099821.91235.15500503.194301.2954027.7194024.92820K562TIA1
POLRMTENSG00000099821.91080.44860494.014701.128903.659802.37180K562TRA2A
POLRMTENSG00000099821.91089.40670822.816000.404802.202701.37320K562TRIM56
POLRMTENSG00000099821.9104.08840210.32870-1.014802.478601.71750K562U2AF2
POLRMTENSG00000099821.91542.199902001.05910-0.375806.148905.12750K562UPF1
POLRMTENSG00000099821.91385.451901780.62220-0.362005.906104.71910K562WDR43
POLRMTENSG00000099821.91903.731002444.85200-0.360903.853902.32070K562WRN
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for POLRMT is not available on ENCORE database.





6 RBPs can affect the splicing of POLRMT :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPOLRMTENSG00000099821.9chr19-633199633310632833632938633424633597-0.373000.000260.02154excludedHepG2AKAP1
A3SSPOLRMTENSG00000099821.9chr19-6184876186306184876185866187046187530.051000.000490.02944longerK562SF3B4
A3SSPOLRMTENSG00000099821.9chr19-6174186175086174186174806175696176550.081000.000050.00810longerHepG2RBM22
A3SSPOLRMTENSG00000099821.9chr19-6199576201126199576200806203646204870.059000.000190.00154longerK562AQR
A3SSPOLRMTENSG00000099821.9chr19-6184876186306184876185866187046187530.060000.000000.00000longerK562PUS1
RIPOLRMTENSG00000099821.9chr19-6174186176406174186174806175696176400.186000.000040.00091includedHepG2SF3A3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for POLRMT is not avaliable on ENCORE database.