PNO1

General Information

Gene Name       : PNO1
Gene ID             : ENSG00000115946.7
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PNO1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PNO1ENSG00000115946.721.5622.7022.13ENCSR000AEF
HepG2PNO1ENSG00000115946.725.8234.2530.04ENCSR985KAT
K562PNO1ENSG00000115946.738.3732.6135.49ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PNO1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PNO1 RNA is bound by 11 proteins.  







eCLIP assay for PNO1 is not avaliable on ENCORE database.





11 proteins are bound to PNO1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr26840268468402795+3'-UTR4.9012711.42666K562PUM2
chr26840202668402079+3'-UTR4.387463.97692K562IGF2BP1
chr26838504768385100+5'-UTR,CDS4.178718.47516K562DDX3X
chr26838500468385047+5'-UTR3.463864.32502K562DDX3X
chr26838551768385573+CDS4.568365.44793K562ZNF622
chr26838961668389732+CDS,intron-Proximal4.168939.40826K562AQR
chr26838516268385268+CDS3.382923.60157HepG2GRWD1
chr26838518068385254+CDS3.638324.24220K562ZNF622
chr26838942768389514+CDS,intron-Proximal4.590318.30573K562AQR
chr26838506668385155+CDS4.158814.01763HepG2GRWD1
chr26838962768389758+CDS,intron-Proximal4.670665.02679K562BUD13
chr26838555968385660+CDS3.235134.59873K562UCHL5
chr26838525168385314+CDS,intron-Proximal3.763825.13777HepG2PRPF8
chr26838986168389916+intron-Distal,intron-Proximal3.884433.02181K562PRPF8
chr26839068568390792+intron-Distal3.600963.51804HepG2HNRNPL
chr26839363668393711+intron-Distal4.127733.79098HepG2SUGP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PNO1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PNO1 is not available on ENCORE database.

  • 97 RBPs can affect the levels of PNO1.  








The Knockdown/knockout RNA-Seq assay for PNO1 is not available on ENCORE database.





97 RBPs can affect the gene expression of PNO1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PNO1ENSG00000115946.3703.40280527.498100.415104.237003.51490HepG2ACO1
PNO1ENSG00000115946.31640.36120670.150801.2914019.5732018.29240HepG2AKAP1
PNO1ENSG00000115946.3767.69430958.43610-0.320203.203902.47410HepG2AUH
PNO1ENSG00000115946.31074.75120763.289500.493604.532503.78800HepG2BOP1
PNO1ENSG00000115946.3388.62940538.29760-0.470003.578302.71700HepG2CALR
PNO1ENSG00000115946.3378.48380700.74820-0.888709.208908.02460HepG2CPSF6
PNO1ENSG00000115946.31016.47570732.247200.473105.654204.79760HepG2CELF1
PNO1ENSG00000115946.3408.36030795.74880-0.962506.148504.71960HepG2DDX59
PNO1ENSG00000115946.3399.52240504.66860-0.337102.187301.57400HepG2DKC1
PNO1ENSG00000115946.3236.49080530.13640-1.1646011.8413010.66810HepG2EIF2S1
PNO1ENSG00000115946.3582.88000359.007500.699105.121103.91840HepG2EIF3D
PNO1ENSG00000115946.3937.72700570.405000.717105.083204.16940HepG2EIF4B
PNO1ENSG00000115946.3979.82430776.775800.334903.023602.15540HepG2EIF4G1
PNO1ENSG00000115946.3459.89710744.11520-0.694206.854605.59990HepG2EIF4G2
PNO1ENSG00000115946.3831.90230515.445700.690508.042006.63140HepG2EWSR1
PNO1ENSG00000115946.3888.06670631.727300.491303.324002.48800HepG2FIP1L1
PNO1ENSG00000115946.3368.55230794.37140-1.1079012.5071011.23750HepG2GPKOW
PNO1ENSG00000115946.3594.04010910.41430-0.616009.351008.12890HepG2HNRNPF
PNO1ENSG00000115946.3496.82420717.31930-0.529906.895505.87520HepG2HNRNPL
PNO1ENSG00000115946.3370.91430758.08160-1.0313011.9127010.72310HepG2HNRNPLL
PNO1ENSG00000115946.3553.80840435.925400.345202.198401.34980HepG2HNRNPM
PNO1ENSG00000115946.3488.18650896.49400-0.8769011.9940010.59270HepG2IGF2BP1
PNO1ENSG00000115946.3761.52200557.382500.450102.998002.29950HepG2IGF2BP2
PNO1ENSG00000115946.3866.66810523.043200.728402.326801.43250HepG2IGF2BP3
PNO1ENSG00000115946.3378.09560482.18940-0.350802.621601.62740HepG2KIF1C
PNO1ENSG00000115946.3997.15710717.494500.474802.886802.03860HepG2LARP4
PNO1ENSG00000115946.31592.10370594.602501.4208011.6948010.46080HepG2MATR3
PNO1ENSG00000115946.3702.32350375.727700.902305.511204.06560HepG2METAP2
PNO1ENSG00000115946.3660.78890511.375100.369702.551301.77270HepG2MSI2
PNO1ENSG00000115946.3292.12500773.10360-1.4041013.4602011.32890HepG2MTPAP
PNO1ENSG00000115946.3298.59110429.38050-0.524103.262101.94030HepG2NAA15
PNO1ENSG00000115946.3898.63310608.615100.562103.316502.62540HepG2NCBP2
PNO1ENSG00000115946.3418.07490672.17070-0.685105.731304.67530HepG2NSUN2
PNO1ENSG00000115946.3613.96060474.480500.371703.001602.12310HepG2PARN
PNO1ENSG00000115946.3925.04740579.390300.6749010.823009.74940HepG2PCBP1
PNO1ENSG00000115946.3786.69400589.558500.416103.927703.30130HepG2PTBP1
PNO1ENSG00000115946.3609.59210745.33010-0.290001.854501.35290HepG2PUF60
PNO1ENSG00000115946.31139.15930791.172000.525809.238608.28770HepG2PUM1
PNO1ENSG00000115946.31217.57330489.600901.3142011.9664010.57700HepG2RAVER1
PNO1ENSG00000115946.31747.26450919.730600.9257023.4383022.22740HepG2RBM22
PNO1ENSG00000115946.3856.56830527.672600.698806.151004.66160HepG2RBM27
PNO1ENSG00000115946.3601.14030428.494600.488302.693601.65000HepG2RCC2
PNO1ENSG00000115946.3636.55480349.339700.865609.794408.72490HepG2RPS19
PNO1ENSG00000115946.3749.84690486.633100.623704.886403.84070HepG2RPS2
PNO1ENSG00000115946.3878.04160496.769300.821608.462806.58220HepG2RPS5
PNO1ENSG00000115946.3689.85420483.320800.513203.086002.26220HepG2RRP9
PNO1ENSG00000115946.3621.51150434.202500.517302.953001.59990HepG2SART3
PNO1ENSG00000115946.3488.46600350.601600.478302.770501.83050HepG2SERBP1
PNO1ENSG00000115946.3983.85000589.042800.740006.010404.99250HepG2SF3A3
PNO1ENSG00000115946.3698.03650497.824800.487605.805504.92870HepG2SMN1
PNO1ENSG00000115946.3729.04000499.505300.545403.246202.19880HepG2SMNDC1
PNO1ENSG00000115946.31239.50310640.672900.9520022.7292021.65540HepG2SRSF1
PNO1ENSG00000115946.31037.88460735.870300.496002.734202.11080HepG2SRSF5
PNO1ENSG00000115946.3591.83460894.46650-0.595808.652207.53810HepG2SRSF7
PNO1ENSG00000115946.3545.34140901.94280-0.7259012.3857011.45290HepG2SSB
PNO1ENSG00000115946.3649.07840462.973500.487402.972801.64420HepG2SSRP1
PNO1ENSG00000115946.31220.35740836.916900.544009.250408.22690HepG2SUCLG1
PNO1ENSG00000115946.3444.63220630.56320-0.504002.930302.23700HepG2SUPV3L1
PNO1ENSG00000115946.3479.63980738.84500-0.623305.372504.41080HepG2TARDBP
PNO1ENSG00000115946.3604.45030422.636200.516103.074102.02580HepG2TFIP11
PNO1ENSG00000115946.3254.42240465.79370-0.872509.330308.50740HepG2TIAL1
PNO1ENSG00000115946.3679.02560540.456500.329201.903701.37230HepG2U2AF1
PNO1ENSG00000115946.31043.51540770.660700.437202.505501.71130HepG2UBE2L3
PNO1ENSG00000115946.3610.82060372.483900.713505.987104.86010HepG2UCHL5
PNO1ENSG00000115946.3398.29550577.36720-0.535702.613501.63860HepG2UPF2
PNO1ENSG00000115946.3329.58050536.95340-0.704207.613705.98270HepG2UTP18
PNO1ENSG00000115946.31232.81010504.348701.2894039.2847037.39990HepG2UTP3
PNO1ENSG00000115946.3479.38400620.72080-0.372801.988401.36590HepG2XRN2
PNO1ENSG00000115946.3388.35640530.78890-0.450804.017803.23270HepG2ZC3H8
PNO1ENSG00000115946.3707.82870477.136100.568905.010103.36280K562AARS
PNO1ENSG00000115946.3746.17600574.160200.378002.406801.79700K562AKAP8L
PNO1ENSG00000115946.3566.26230753.99190-0.413102.684301.82490K562BOP1
PNO1ENSG00000115946.3640.427301020.64470-0.672403.119101.98080K562CNOT7
PNO1ENSG00000115946.3482.16980801.70630-0.733509.072007.63330K562CPSF6
PNO1ENSG00000115946.3980.15160695.355700.495206.607204.56550K562DDX27
PNO1ENSG00000115946.32738.187101158.063601.2414036.2015034.11060K562DDX47
PNO1ENSG00000115946.3877.78290617.927600.506305.603104.30280K562DKC1
PNO1ENSG00000115946.3822.417301346.73030-0.711509.831808.60110K562EIF2S2
PNO1ENSG00000115946.3946.76690407.589201.215808.744106.91980K562EIF3A
PNO1ENSG00000115946.31221.04560533.273101.195109.080807.64200K562EIF3G
PNO1ENSG00000115946.3521.30870815.72370-0.645905.995104.72660K562FMR1
PNO1ENSG00000115946.3440.60830691.40220-0.650005.320104.00850K562FTO
PNO1ENSG00000115946.31284.74660456.536201.4926046.0831043.79170K562FXR1
PNO1ENSG00000115946.3548.97540765.42950-0.479503.782002.85930K562GPKOW
PNO1ENSG00000115946.3930.26890520.431000.837807.326805.23310K562HNRNPK
PNO1ENSG00000115946.31185.86120902.019200.394602.633401.72740K562HNRNPM
PNO1ENSG00000115946.3405.47420653.58840-0.688804.475303.25390K562KRR1
PNO1ENSG00000115946.3953.44270547.553800.800008.163106.68330K562MAGOH
PNO1ENSG00000115946.3811.98490546.484300.571205.973604.54560K562MATR3
PNO1ENSG00000115946.3731.14780960.35700-0.393402.393301.69480K562NSUN2
PNO1ENSG00000115946.3749.84510487.236900.621905.819604.38870K562PCBP2
PNO1ENSG00000115946.3705.88830962.01140-0.446603.062402.18790K562PCBP3
PNO1ENSG00000115946.3731.536601008.24930-0.462903.430501.66590K562PKM
PNO1ENSG00000115946.31386.96570649.918401.0935018.2497016.30450K562PRPF8
PNO1ENSG00000115946.31214.85070531.962501.1913026.4647024.51380K562PTBP1
PNO1ENSG00000115946.32448.461801812.779900.433604.172903.17780K562PUF60
PNO1ENSG00000115946.3682.29220510.236900.419102.980302.10520K562RBM22
PNO1ENSG00000115946.3739.32410536.908000.461402.495101.46480K562NELFE
PNO1ENSG00000115946.31553.04080662.094601.2299019.5703017.41950K562RPS19
PNO1ENSG00000115946.3617.43900314.252700.974305.038903.63240K562RPS3
PNO1ENSG00000115946.31133.05380657.546900.7850011.074309.00910K562SAFB
PNO1ENSG00000115946.3894.27360679.787300.395502.821901.36470K562SDAD1
PNO1ENSG00000115946.3804.79890521.470100.625906.773005.67710K562SRSF1
PNO1ENSG00000115946.3429.03520701.42180-0.709202.758201.33820K562SUPT6H
PNO1ENSG00000115946.31277.25300740.139300.7871013.2377011.43640K562SYNCRIP
PNO1ENSG00000115946.3282.31150450.48340-0.674203.116402.11800K562TIAL1
PNO1ENSG00000115946.3595.652701018.27860-0.773605.885104.88150K562UPF1
PNO1ENSG00000115946.3462.43810871.32240-0.913906.268504.91960K562WDR3
PNO1ENSG00000115946.31166.91360905.980800.365003.890002.89730K562WDR43
PNO1ENSG00000115946.31020.43240543.114800.909804.327802.21960K562XRCC6
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PNO1 is not available on ENCORE database.





1 RBPs can affect the splicing of PNO1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPNO1ENSG00000115946.3chr2+6840047868400549683896776838979568401866684033700.052000.000770.03667includedK562HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PNO1 is not avaliable on ENCORE database.